Search Results - (Author, Cooperation:K. C. Lloyd)
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1K. C. Lloyd ; T. Meehan ; A. Beaudet ; S. Murray ; K. Svenson ; C. McKerlie ; D. West ; I. Morse ; H. Parkinson ; S. Brown ; A. M. Mallon ; M. Moore
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-07-25Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animal Experimentation/*standards ; Animals ; Electronic Health Records ; Female ; Genomics ; Humans ; Male ; Metabolomics ; Mice ; Mice, Knockout ; National Institutes of Health (U.S.) ; Precision Medicine/*economics/*trends ; United StatesPublished by: -
2Staff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
3Battey, James F ; Bradley, Allan ; Bucan, Maja ; Capecchi, Mario ; Collins, Francis S ; Dove, William F ; Duyk, Geoffrey ; Dymecki, Susan ; Eppig, Janan T ; Grieder, Franziska B ; Heintz, Nathaniel ; Hicks, Geoff ; Insel, Thomas R ; Joyner, Alexandra ; Koller, Beverly H ; Lloyd, K C Kent ; Magnuson, Terry ; Moore, Mark W ; Nagy, Andras ; Pollock, Jonathan D ; Roses, Allen D ; Sands, Arthur T ; Seed, Brian ; Skarnes, William C ; Snoddy, Jay
[s.l.] : Nature Publishing Group
Published 2004Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] Now that the human and mouse genome sequences are known, attention has turned to elucidating gene function and identifying gene products that might have therapeutic value. The laboratory mouse (Mus musculus) has had a prominent role in the study of human disease mechanisms throughout the rich, ...Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1432-0878Keywords: Enteric nervous system ; Stomach ; Vasoactive intestinal peptide ; Galanin ; Gastrin-releasing peptide ; Substance P-DogSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary The distribution of nerve cell bodies and fibres in the canine stomach was investigated using antibodies to the general neuronal marker, neuron-specific enolase. Prominent ganglia containing many reactive nerve cells were found in the myenteric plexus of the gastric corpus and antrum. Nerve cells were absent from the submucosa of the corpus and were extremely rare in the antrum. Renoval of areas of longitudinal muscle and myenteric plexus from the corpus (myectomy), with 7 days allowed for axon degeneration, resulted in the loss of fibres reactive for galanin, gastrin-releasing peptide, substance P and vasoactive intestinal peptide from both the circular muscle and mucosa in the area covered by the lesion. Combined vagotomy and sympathetic denervation did not significantly affect these fibres, but did cause fibres reactive for calcitonin gene-related peptide to degenerate. It is concluded that the myenteric plexus of the gastric corpus, like the myenteric plexus of the small intestine and colon, is the source of nerve fibres innervating the circular muscle, but, in contrast to other regions of the gastrointestinal tract, myenteric ganglia, not submucous ganglia, are the major, or sole, source of the intrinsic innervation of the mucosa.Type of Medium: Electronic ResourceURL: -
5Raybould, Helen E. ; Zittel, Tilman T. ; Holzer, Helge H. ; Kent Lloyd, K. C. ; Meyer, James H.
Springer
Published 1994Staff ViewISSN: 1573-2568Keywords: CCK ; sensory ; nutrients ; intestinal feedback inhibition ; capsaicinSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The ability of nutrients in the intestinal lumen to exert feedback control over the proximal gastrointestinal tract function is well recognized, yet the control mechanisms are poorly defined. There is evidence that extrinsic sensory pathways from the intestine are required to initiate this regulatory process. Furthermore, CCK appears to be involved in the gastric response to several intestinal stimuli, such as fat, carbohydrate and protein. Our hypothesis is that nutrients release CCK from the intestine, which then stimulates intestinal mucosal afferents to signal reflex changes in gastric motor function and thus inhibit gastric emptying.Type of Medium: Electronic ResourceURL: