Search Results - (Author, Cooperation:K. Bergsteinsdottir)
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1Latest Papers from Table of Contents or Articles in PressU. Styrkarsdottir ; G. Thorleifsson ; P. Sulem ; D. F. Gudbjartsson ; A. Sigurdsson ; A. Jonasdottir ; A. Oddsson ; A. Helgason ; O. T. Magnusson ; G. B. Walters ; M. L. Frigge ; H. T. Helgadottir ; H. Johannsdottir ; K. Bergsteinsdottir ; M. H. Ogmundsdottir ; J. R. Center ; T. V. Nguyen ; J. A. Eisman ; C. Christiansen ; E. Steingrimsson ; J. G. Jonasson ; L. Tryggvadottir ; G. I. Eyjolfsson ; A. Theodors ; T. Jonsson ; T. Ingvarsson ; I. Olafsson ; T. Rafnar ; A. Kong ; G. Sigurdsson ; G. Masson ; U. Thorsteinsdottir ; K. Stefansson
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-05-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Australia ; Biliary Tract Neoplasms/*genetics ; Bone Density/*genetics ; Carcinoma, Squamous Cell/*genetics ; Codon, Nonsense/*genetics ; Denmark ; Down-Regulation/genetics ; Female ; Heterozygote ; Humans ; Iceland ; Male ; Menarche/genetics ; Mice ; Mice, Knockout ; Osteoporotic Fractures/*genetics ; Phenotype ; Receptors, G-Protein-Coupled/chemistry/deficiency/*genetics/metabolism ; Skin Neoplasms/*genetics ; Testosterone/analysis ; Water-Electrolyte Imbalance/*geneticsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1573-7381Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Previous studies, showing that cultured rat Schwann cells could be induced to express MHC class II molecules, raised the possibility that Schwann cells in living nerves might, under some conditions, express MHC class II molecules and take part in activation of T lymphocytes. In the present work, the ability of myelin- and non-myelin-forming Schwann cellsin vivo to express MHC class II molecules was investigated. Lymphokines or bacterial antigens were injected into the living sciatic nerve of adult rats. Examination of the nerves three days after injection of interferon-γ or six days after injection of either tumour necrosis factor, antigens from mycobacterium leprae or whole mycobacteria leprae, revealed strong MHC class II immunostaining on some myelin-forming Schwann cells in the vicinity of the injection site. Very few non-myelin-forming cells expressed MHC class II molecules. MHC class II positive mononuclear cells were present in the injected nerves and endothelial cells of capillaries expressed high levels of MHC class II antigens. Crushing the sciatic nerve without injection of factors also induced MHC class II molecules on a few Schwann cells. Thus rat Schwann cells can be induced to express MHC class II moleculesin vivo asin vitro. This strengthens the possibility that in living nerves Schwann cells are able to function as accessory cells in the initiation or augmentation of T cell-mediated immune responses.Type of Medium: Electronic ResourceURL: