Search Results - (Author, Cooperation:J. Wilkinson)
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1Hanif Esmail, Rachel P. Lai, Maia Lesosky, Katalin A. Wilkinson, Christine M. Graham, Stuart Horswell, Anna K. Coussens, Clifton E. Barry III, Anne O’Garra, Robert J. Wilkinson
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-01-31Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
2Staff View
Publication Date: 2018-01-07Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Smoking and tobaccoPublished by: -
3Hong, W. C., Wasko, M. J., Wilkinson, D. S., Hiranita, T., Li, L., Hayashi, S., Snell, D. B., Madura, J. D., Surratt, C. K., Katz, J. L.
The American Society for Pharmacology and Experimental Therapeutics
Published 2018Staff ViewPublication Date: 2018-08-18Publisher: The American Society for Pharmacology and Experimental TherapeuticsPrint ISSN: 0022-3565Electronic ISSN: 1521-0103Topics: MedicinePublished by: -
4Akul Singhania; Raman Verma; Christine M. Graham; Jo Lee; Trang Tran; Matthew Richardson; Patrick Lecine; Philippe Leissner; Matthew P. R. Berry; Robert J. Wilkinson; Karine Kaiser; Marc Rodrigue; Gerrit Woltmann; Pranabashis Haldar; Anne O’Garra
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-06-20Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
5M. F. Berger ; M. S. Lawrence ; F. Demichelis ; Y. Drier ; K. Cibulskis ; A. Y. Sivachenko ; A. Sboner ; R. Esgueva ; D. Pflueger ; C. Sougnez ; R. Onofrio ; S. L. Carter ; K. Park ; L. Habegger ; L. Ambrogio ; T. Fennell ; M. Parkin ; G. Saksena ; D. Voet ; A. H. Ramos ; T. J. Pugh ; J. Wilkinson ; S. Fisher ; W. Winckler ; S. Mahan ; K. Ardlie ; J. Baldwin ; J. W. Simons ; N. Kitabayashi ; T. Y. MacDonald ; P. W. Kantoff ; L. Chin ; S. B. Gabriel ; M. B. Gerstein ; T. R. Golub ; M. Meyerson ; A. Tewari ; E. S. Lander ; G. Getz ; M. A. Rubin ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Carrier Proteins/genetics ; Case-Control Studies ; Cell Adhesion Molecules/genetics ; Chromatin/genetics/metabolism ; Chromosome Aberrations ; Chromosome Breakpoints ; Epigenesis, Genetic/genetics ; Gene Expression Regulation, Neoplastic ; Genome, Human/*genetics ; Humans ; Male ; PTEN Phosphohydrolase/genetics/metabolism ; Prostatic Neoplasms/*genetics ; Recombination, Genetic/genetics ; Signal Transduction/genetics ; Transcription, GeneticPublished by: -
6Semchenko, M., Leff, J. W., Lozano, Y. M., Saar, S., Davison, J., Wilkinson, A., Jackson, B. G., Pritchard, W. J., De Long, J. R., Oakley, S., Mason, K. E., Ostle, N. J., Baggs, E. M., Johnson, D., Fierer, N., Bardgett, R. D.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-29Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
7P. Nicolas ; U. Mader ; E. Dervyn ; T. Rochat ; A. Leduc ; N. Pigeonneau ; E. Bidnenko ; E. Marchadier ; M. Hoebeke ; S. Aymerich ; D. Becher ; P. Bisicchia ; E. Botella ; O. Delumeau ; G. Doherty ; E. L. Denham ; M. J. Fogg ; V. Fromion ; A. Goelzer ; A. Hansen ; E. Hartig ; C. R. Harwood ; G. Homuth ; H. Jarmer ; M. Jules ; E. Klipp ; L. Le Chat ; F. Lecointe ; P. Lewis ; W. Liebermeister ; A. March ; R. A. Mars ; P. Nannapaneni ; D. Noone ; S. Pohl ; B. Rinn ; F. Rugheimer ; P. K. Sappa ; F. Samson ; M. Schaffer ; B. Schwikowski ; L. Steil ; J. Stulke ; T. Wiegert ; K. M. Devine ; A. J. Wilkinson ; J. M. van Dijl ; M. Hecker ; U. Volker ; P. Bessieres ; P. Noirot
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-03-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological ; Algorithms ; Bacillus subtilis/*genetics/*physiology ; Binding Sites ; Gene Expression Profiling ; *Gene Expression Regulation, Bacterial ; Gene Regulatory Networks ; Oligonucleotide Array Sequence Analysis ; *Promoter Regions, Genetic ; RNA, Antisense/genetics/metabolism ; RNA, Bacterial/genetics/metabolism ; RNA, Messenger/genetics/metabolism ; Regulon ; Sigma Factor/metabolism ; Terminator Regions, Genetic ; *Transcription, Genetic ; *TranscriptomePublished by: -
8K. Lindblad-Toh ; M. Garber ; O. Zuk ; M. F. Lin ; B. J. Parker ; S. Washietl ; P. Kheradpour ; J. Ernst ; G. Jordan ; E. Mauceli ; L. D. Ward ; C. B. Lowe ; A. K. Holloway ; M. Clamp ; S. Gnerre ; J. Alfoldi ; K. Beal ; J. Chang ; H. Clawson ; J. Cuff ; F. Di Palma ; S. Fitzgerald ; P. Flicek ; M. Guttman ; M. J. Hubisz ; D. B. Jaffe ; I. Jungreis ; W. J. Kent ; D. Kostka ; M. Lara ; A. L. Martins ; T. Massingham ; I. Moltke ; B. J. Raney ; M. D. Rasmussen ; J. Robinson ; A. Stark ; A. J. Vilella ; J. Wen ; X. Xie ; M. C. Zody ; J. Baldwin ; T. Bloom ; C. W. Chin ; D. Heiman ; R. Nicol ; C. Nusbaum ; S. Young ; J. Wilkinson ; K. C. Worley ; C. L. Kovar ; D. M. Muzny ; R. A. Gibbs ; A. Cree ; H. H. Dihn ; G. Fowler ; S. Jhangiani ; V. Joshi ; S. Lee ; L. R. Lewis ; L. V. Nazareth ; G. Okwuonu ; J. Santibanez ; W. C. Warren ; E. R. Mardis ; G. M. Weinstock ; R. K. Wilson ; K. Delehaunty ; D. Dooling ; C. Fronik ; L. Fulton ; B. Fulton ; T. Graves ; P. Minx ; E. Sodergren ; E. Birney ; E. H. Margulies ; J. Herrero ; E. D. Green ; D. Haussler ; A. Siepel ; N. Goldman ; K. S. Pollard ; J. S. Pedersen ; E. S. Lander ; M. Kellis
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-10-14Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Disease ; *Evolution, Molecular ; Exons/genetics ; Genome/*genetics ; Genome, Human/*genetics ; Genomics ; Health ; Humans ; Mammals/*genetics ; Molecular Sequence Annotation ; Phylogeny ; RNA/classification/genetics ; Selection, Genetic/genetics ; Sequence Alignment ; Sequence Analysis, DNAPublished by: -
9F. C. Jones ; M. G. Grabherr ; Y. F. Chan ; P. Russell ; E. Mauceli ; J. Johnson ; R. Swofford ; M. Pirun ; M. C. Zody ; S. White ; E. Birney ; S. Searle ; J. Schmutz ; J. Grimwood ; M. C. Dickson ; R. M. Myers ; C. T. Miller ; B. R. Summers ; A. K. Knecht ; S. D. Brady ; H. Zhang ; A. A. Pollen ; T. Howes ; C. Amemiya ; J. Baldwin ; T. Bloom ; D. B. Jaffe ; R. Nicol ; J. Wilkinson ; E. S. Lander ; F. Di Palma ; K. Lindblad-Toh ; D. M. Kingsley
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-04-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological/*genetics ; Alaska ; Animals ; Aquatic Organisms/genetics ; *Biological Evolution ; Chromosome Inversion/genetics ; Chromosomes/genetics ; Conserved Sequence/genetics ; Ecotype ; Female ; Fresh Water ; Genetic Variation/genetics ; Genome/*genetics ; Genomics ; Molecular Sequence Data ; Seawater ; Sequence Analysis, DNA ; Smegmamorpha/*geneticsPublished by: -
10A. Alici, P. Antonioli, S. Arcelli, M. Basile, F. Bellini, F. Carnesecchi, D. Cavazza, L. Cifarelli, F. Cindolo, M. Colocci, A. De Caro, D. De Gruttola, S. De Pasquale, M. Fusco Girard, D. Hatzifotiadou, N. Jacazio, Z.Liu, O. Maragoto Rodriguez, A. Margotti, E. Meninno, R. Nania, F. Noferini, O. Pinazza, R. Preghenella, E. Scapparone, G. Scioli, J. Wilkinson, M.C.S. Williams, C. Zampolli, A. Zichichi and R. Zuyeuski
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-09-15Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
11Ashley J. Winter, Christopher Williams, Michail N. Isupov, Hannah Crocker, Mariya Gromova, Philip Marsh, Oliver J. Wilkinson, Mark S. Dillingham, Nicholas J. Harmer, Richard W. Titball, Matthew P. Crump
The American Society for Biochemistry and Molecular Biology (ASBMB)
Published 2018Staff ViewPublication Date: 2018-12-15Publisher: The American Society for Biochemistry and Molecular Biology (ASBMB)Print ISSN: 0021-9258Electronic ISSN: 1083-351XTopics: BiologyChemistry and PharmacologyPublished by: -
12J. M. Buescher ; W. Liebermeister ; M. Jules ; M. Uhr ; J. Muntel ; E. Botella ; B. Hessling ; R. J. Kleijn ; L. Le Chat ; F. Lecointe ; U. Mader ; P. Nicolas ; S. Piersma ; F. Rugheimer ; D. Becher ; P. Bessieres ; E. Bidnenko ; E. L. Denham ; E. Dervyn ; K. M. Devine ; G. Doherty ; S. Drulhe ; L. Felicori ; M. J. Fogg ; A. Goelzer ; A. Hansen ; C. R. Harwood ; M. Hecker ; S. Hubner ; C. Hultschig ; H. Jarmer ; E. Klipp ; A. Leduc ; P. Lewis ; F. Molina ; P. Noirot ; S. Peres ; N. Pigeonneau ; S. Pohl ; S. Rasmussen ; B. Rinn ; M. Schaffer ; J. Schnidder ; B. Schwikowski ; J. M. Van Dijl ; P. Veiga ; S. Walsh ; A. J. Wilkinson ; J. Stelling ; S. Aymerich ; U. Sauer
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-03-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Adaptation, Physiological ; Algorithms ; Bacillus subtilis/*genetics/*metabolism ; Bacterial Proteins/metabolism ; Computer Simulation ; Data Interpretation, Statistical ; Gene Expression Regulation, Bacterial ; *Gene Regulatory Networks ; Genome, Bacterial ; Glucose/*metabolism ; Malates/*metabolism ; Metabolic Networks and Pathways/*genetics ; Metabolome ; Metabolomics ; Models, Biological ; Operon ; Promoter Regions, Genetic ; Transcription Factors/metabolism ; Transcription, GeneticPublished by: -
13Adam D. Piascik, Ruohao Li, Harry J. Wilkinson, Jennifer C. Green, Andrew E. Ashley
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-08-21Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
14Staff View
Type of Medium: bookPublication Date: 1987Keywords: Führung ; Organisationssoziologie ; Schule ; Schulleitung ; Sekundarschule ; GroßbritannienLanguage: EnglishNote: Literaturangaben 100 -
15Staff View
Type of Medium: bookPublication Date: 2003Keywords: SchottlandLanguage: English -
16POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer [Research Papers]Huang, Y.-H., Klingbeil, O., He, X.-Y., Wu, X. S., Arun, G., Lu, B., Somerville, T. D. D., Milazzo, J. P., Wilkinson, J. E., Demerdash, O. E., Spector, D. L., Egeblad, M., Shi, J., Vakoc, C. R.
Cold Spring Harbor Laboratory Press
Published 2018Staff ViewPublication Date: 2018-07-03Publisher: Cold Spring Harbor Laboratory PressPrint ISSN: 0890-9369Topics: BiologyPublished by: -
17WILKINSON, J. M. ; LE DU, Y. L. P. ; COOK, J. E. ; BAKER, R. D.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1365-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Two experiments were carried out to determine whether the differences in intake and feeding value previously shown between two grass cultivars when offered to ruminants as chopped artificially dehydrated (dried) material could also be demonstrated when the grasses were offered in other forms. Two cultivars of tetraploid Italian ryegrass (Lolium multiflorum), Sabalan and Tetila, were established in the same field in 1975. In 1976 they were grazed and conserved (two cuts of primary growth) as dried material or as silage.The composition of the herbage selected at pasture and conserved showed higher concentrations of normal detergent fibre and acid detergent fibre in the dry matter for Tetila than for Sabalan, but differences between cultivars in digestibility were small. In both grazing and winter feeding trials differences in voluntary intake between the two cultivars were not significant, but at pasture young beef cattle spent less time grazing and tended to spend more time ruminating on Tetila than Sabalan. There was no measure of animal performance at pasture but liveweight gain was 15% higher for Sabalan than Tetila when both were offered to young beef cattle as the sole feed of dried grass or of silage. The voluntary intakes of the three forms of feed were very similar, which in part reflected a similarity in digestibility. However, gains were lower for calves given silage than those given dried grass. This may have been due to a lower efficiency in the utilization of the nitrogeneous components of silage for tissue growth than those of dried grass.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1365-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: To test whether or not the ‘stay-green’ (SG) characteristic confers benefits in terms of crop yield or distribution of dry matter (DM) in selected forage maize cultivars, an experiment was conducted in 1998 and 1999 at two sites in England: Writtle College, Essex and the University of Leeds, West Yorkshire. Five SG and five conventional (C) cultivars of forage maize were grown in replicated field-scale plots at each site in both years. One-metre lengths of single rows in each plot were harvested by hand, leaving a 20-cm stubble, on four occasions each year over 3-week periods (harvest 1 to harvest 4), prior to the harvest of the remainder of the fields. Plants were chopped, mixed and a subsample taken for determination of DM content by oven-drying. Mean yields of whole plant DM were similar between SG and C cultivars. Both yield of DM and proportion of ear in the total plant DM increased from harvest 1 to harvest 4 (P 〈 0·01). The increase in DM yield between harvest 1 and harvest 4 was greater for C than for SG cultivars (P 〈 0·05). Within sites there were no differences in the concentration of whole plant DM between SG and C cultivars, which increased from harvest 1 to harvest 4 (P 〈 0·001). The proportion of ear DM in the whole plant DM tended to be higher for C than for SG cultivars in both years and increased (P 〈 0·001) from harvest 1 to harvest 4. The concentration of DM in the ear fraction was higher (P 〈 0·05) for C than for SG cultivars. We conclude that differences between SG and C cultivars of forage maize are likely to be relatively small when grown in the English climate and harvested after the same growing period.Type of Medium: Electronic ResourceURL: -
19Hillman, J. P. ; Hill, J. ; Morgan, J. E. ; Wilkinson, J. M.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The recycling of sewage sludge or biosolids to grassland is strategically important in the European Union (EU) and its use is tightly regulated to control the risk of pathogen transfer to animals and the food chain. Sewage sludges not only contain valuable concentrations of beneficial nutrients, but also elevated concentrations of potentially toxic metals (PTM) compared with average background concentrations in the soil. The EC and UK regulations refer to six PTM, Cd, Pb, Cu, Zn, Ni and Hg, with provisional regulations for Cr, that have to be controlled to prevent detrimental effects on soil and animal health. Despite these regulations, there is still a danger that grazing animals may ingest elevated concentrations of PTM. Biosolids may adhere to herbage after the surface application of sewage sludge to grassland. The repeated surface application of sewage sludge to grassland can lead to elevated concentrations of PTM at the soil surface that may be ingested, together with soil and herbage, by grazing ruminants. This may lead to accumulation of Cd or Pb in liver or kidney. The risk to the human food chain is considered to be low, but the impact on the environment is still unknown. There is little information, for example, on the amount of soil and PTMs that may become incorporated into conserved grass. At present EU and UK legislation and voluntary codes of practice have been developed to protect animal from pathogens in sewage sludge and to minimize any potential risks from accumulation of PTM. The background and implementation of the legislation are examined in this review, and the source and mechanisms of accumulation of PTM by the grazing animal are evaluated.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1365-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Two studies are described in which the behaviour of 24 seven-month-old Friesian steer calves was observed. The first study (G1) was undertaken at the time of turnout to pasture, and the second (G2) 5 days later. The calves appeared to adapt rapidly to the change in environment, though in study G1 grazing was frequently interrupted. In study G2 the calves showed normal behaviour patterns and spent a total of 4.25 hours grazing.There was a positive correlation between age and weight at turnout and time spent grazing in study G1. However, this relationship was not apparent in G2, and there was no relationship between time spent grazing in G1 and G2.Mean weight loss upon turnout was 7.44% of live weight, in spite of the feeding of hay and barley at grass. There was no relationship between weight at turnout and subsequent weight loss.The results confirmed other experimental findings which suggest that weight loss at turnout is largely a reflection of changes in the weight of alimentary tract contents, rather than an inability to adapt to the change in environment.The calves were grazed at two intensities (‘low’ and ‘standard’) during the grazing season. Growth rate in winter and weight at turnout were negatively correlated with growth rate in the first month of the grazing season. This relationship was more apparent in the ‘low’ intensity group which received a liberal daily herbage allowance at this stage of the season. Partial correlation analysis, in which pre-grazing growth rate was held constant, indicated that weight and age had little independent influence on growth rate at grass, though there was a positive relationship between weight for age at turnout and gain during the grazing season.The importance of a target weight at turnout is discussed in relation to the 18-month beef production system. It is concluded that younger, lighter, cattle at turnout may not be at a disadvantage when adequate amounts of herbage are on offer early in the grazing season.Type of Medium: Electronic ResourceURL: