Search Results - (Author, Cooperation:J. Wakefield)
-
1Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-09-29Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressB. Vernot ; S. Tucci ; J. Kelso ; J. G. Schraiber ; A. B. Wolf ; R. M. Gittelman ; M. Dannemann ; S. Grote ; R. C. McCoy ; H. Norton ; L. B. Scheinfeldt ; D. A. Merriwether ; G. Koki ; J. S. Friedlaender ; J. Wakefield ; S. Paabo ; J. M. Akey
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; DNA/*genetics ; Genetic Variation ; Genome, Human/*genetics ; Humans ; Melanesia ; Neanderthals/*genetics ; Oceanic Ancestry Group/*genetics ; Sequence Analysis, DNAPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 0020-7381Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
6Latest Papers from Table of Contents or Articles in PressCohen-Cline, H., Beresford, S. A. A., Barrington, W. E., Matsueda, R. L., Wakefield, J., Duncan, G. E.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-02-13Publisher: BMJ Publishing GroupPrint ISSN: 0143-005XElectronic ISSN: 1470-2738Topics: MedicinePublished by: -
7Latest Papers from Table of Contents or Articles in PressTobin, J. V., Zimmer, D. P., Shea, C., Germano, P., Bernier, S. G., Liu, G., Long, K., Miyashiro, J., Ranganath, S., Jacobson, S., Tang, K., Im, G.-Y. J., Sheppeck, J., Moore, J. D., Sykes, K., Wakefield, J., Sarno, R., Banijamali, A. R., Profy, A. T., Milne, G. T., Currie, M. G., Masferrer, J. L.
The American Society for Pharmacology and Experimental Therapeutics
Published 2018Staff ViewPublication Date: 2018-05-09Publisher: The American Society for Pharmacology and Experimental TherapeuticsPrint ISSN: 0022-3565Electronic ISSN: 1521-0103Topics: MedicinePublished by: -
8Articles: DFG German National LicensesScott, J. R. ; Wakefield, J. C. ; Russell, P. W. ; Orndorff, P. E. ; Froehlich, B. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: CS1 pili are filamentous proteinaceous appendages found on many enterotoxigenic Escherichia coli (ETEC) strains isolated from human diarrhoeal disease. They are thought to effect colonization of the upper intestine by facilitating binding to human ileal epithelial cells. We have identified a gene, cooB, which lies directly upstream of cooA, the gene that encodes the major structural CS1 protein. When translated in vitro, the protein product of cooB migrates in sodium dodecyl sulphate/polyacrylamide gel with an apparent molecular mass of 26 kDa, which is consistent with that predicted from its DNA sequence. We constructed a mutant allele (cooB-1) by insertion of the omega fragment, which inhibits transcription and translation, into the cooB gene in vitro. In a derivative of an ETEC strain with the cooB-1 mutation (JEF100) and a plasmid that encodes Rns (pEU2030), the positive regulator required for CS1 expression, no cooB and a greatly reduced level of cooA product was detectable in total cell extracts. The reduction of cooA in this strain appears to result from polarity of the cooB mutation because introduction of the wild-type cooA gene in trans causes production of CooA protein, which is found in cell pellet extracts, in extracts containing only surface proteins and in the culture supernatant. Therefore, in the absence of CooB, CooA is stable and it is transported through both inner and outer membranes. However, the cooB-1 strain with cooA in trans does not cause haemagglutination of bovine erythrocytes (the model system used to assay adherence mediated by coli surface antigen 1 (CS1) pili). Electron microscopy reveals that there are no pili present on the cell surface or in the culture medium in which this strain was grown. Thus, although it is not required for stability or transport of the major CS1 pilin protein, CooB is needed for assembly of CooA into pili. The relationship of these gene products to those of other pili is discussed.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesHirsch, V.M. ; Sharkey, M.E. ; Brown, C.R. ; Brichacek, B. ; Goldstein, S. ; Wakefield, J. ; Byrum, R. ; Elkins, W.R. ; Hahn, B.H. ; Lifson, J.D. ; Stevenson, M.
[s.l.] : Nature America Inc.
Published 1998Staff ViewISSN: 1546-170XSource: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] The viral accessory protein Vpx is required for productive in vitro infection of macrophages by simian immunodeficiency virus from sooty mangabey monkeys (SIVSM). To evaluate the roles of Vpx and macrophage infection in vivo, we inoculated pigtailed macaques intravenously or intrarectally with ...Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Saccharin manufactured by the same process as that used in the WARF studies, namely by the Remson-Fahlberg process, in which 0-toluene sulphonamide is the starting material, is known to contain this compound as an impurity. A very recent analysis of the saccharin used in our experiment showed it ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] This communication reports on pulse-height spectra obtained from lithium-drifted p-i-n junctions in germanium, for which the atomic number is 32 compared with 14 for silicon. Lithium-drifted p-i-n junctions were prepared in germanium using a technique similar to that used by other workers2 in ...Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesBULLOUGH, R. ; NEWMAN, R. C. ; WAKEFIELD, J. ; WILLIS, J. B.
[s.l.] : Nature Publishing Group
Published 1959Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A possible mechanism for the growth of the precipitates is suggested by the observation that these are discrete and lie along the dislocation lines, that is, the impurities migrate to the dislocation and then flow rapidly down the core to sites where precipitates have nucleated. Such a possibility ...Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0022-3697Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0038-1101Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0378-4363Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0250-6874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesMurphy, D. V. ; Macdonald, A. J. ; Stockdale, E. A. ; Goulding, K. W. T. ; Fortune, S. ; Gaunt, J. L. ; Poulton, P. R. ; Wakefield, J. A. ; Webster, C. P. ; Wilmer, W. S.
Springer
Published 2000Staff ViewISSN: 1432-0789Keywords: Key words Dissolved organic nitrogen ; Soluble organic nitrogen ; Nitrogen transformations ; Nitrogen loss ; LeachingSource: Springer Online Journal Archives 1860-2000Topics: BiologyGeosciencesAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract The existence of soluble organic forms of N in rain and drainage waters has been known for many years, but these have not been generally regarded as significant pools of N in agricultural soils. We review the size and function of both soluble organic N extracted from soils (SON) and dissolved organic N present in soil solution and drainage waters (DON) in arable agricultural soils. SON is of the same order of magnitude as mineral N and of equal size in many cases; 20–30 kg SON-N ha–1 is present in a wide range of arable agricultural soils from England. Its dynamics are affected by mineralisation, immobilisation, leaching and plant uptake in the same way as those of mineral N, but its pool size is more constant than that of mineral N. DON can be sampled from soil solution using suction cups and collected in drainage waters. Significant amounts of DON are leached, but this comprises only about one-tenth of the SON extracted from the same soil. Leached DON may take with it nutrients, chelated or complexed metals and pesticides. SON/DON is clearly an important pool in N transformations and plant uptake, but there are still many gaps in our understanding.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesSchoenthaler, S.J. ; Amos, S.P. ; Doraz, W.E. ; Kelly, M.A. ; Muedeking, G.D. ; Pinto, J. ; Wakefield, J.
Amsterdam : ElsevierStaff ViewISSN: 0191-8869Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 0191-8869Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesSchoenthaler, S.J. ; Amos, S.P. ; Doraz, W.E. ; Kelly, M.A. ; Pinto, J. ; Wakefield, J.
Amsterdam : ElsevierStaff ViewISSN: 0191-8869Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: