Search Results - (Author, Cooperation:J. Trappe)
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1C. W. McNamara ; M. C. Lee ; C. S. Lim ; S. H. Lim ; J. Roland ; A. Nagle ; O. Simon ; B. K. Yeung ; A. K. Chatterjee ; S. L. McCormack ; M. J. Manary ; A. M. Zeeman ; K. J. Dechering ; T. R. Kumar ; P. P. Henrich ; K. Gagaring ; M. Ibanez ; N. Kato ; K. L. Kuhen ; C. Fischli ; M. Rottmann ; D. M. Plouffe ; B. Bursulaya ; S. Meister ; L. Rameh ; J. Trappe ; D. Haasen ; M. Timmerman ; R. W. Sauerwein ; R. Suwanarusk ; B. Russell ; L. Renia ; F. Nosten ; D. C. Tully ; C. H. Kocken ; R. J. Glynne ; C. Bodenreider ; D. A. Fidock ; T. T. Diagana ; E. A. Winzeler
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 1-Phosphatidylinositol 4-Kinase/*antagonists & ; inhibitors/chemistry/genetics/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Binding Sites ; Cytokinesis/drug effects ; Drug Resistance/drug effects/genetics ; Fatty Acids/metabolism ; Female ; Hepatocytes/parasitology ; Humans ; Imidazoles/metabolism/pharmacology ; Life Cycle Stages/drug effects ; Macaca mulatta ; Malaria/*drug therapy/*parasitology ; Male ; Models, Biological ; Models, Molecular ; Phosphatidylinositol Phosphates/metabolism ; Plasmodium/classification/*drug effects/*enzymology/growth & development ; Pyrazoles/metabolism/pharmacology ; Quinoxalines/metabolism/pharmacology ; Reproducibility of Results ; Schizonts/cytology/drug effects ; rab GTP-Binding Proteins/genetics/metabolismPublished by: -
2LI, C. Y. ; Lu, K. C. ; TRAPPE, J. M. ; BOLLEN, W. B.
[s.l.] : Nature Publishing Group
Published 1967Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Many fungi, including Basidiomycetes such as Collybia tuberosct (Fr.) Quel. and Lentinus tigrinus Fr., can use \ nitrate nitrogen2'3 and therefore presumably produce nitrat reductase, the enzyme required for reduction of nitrate to usable ammonium. Other fungi, however, cannot use nitrate nitrogen, ...Type of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 1432-1890Keywords: Vesicular-arbuscular mycorrhizae ; Abies lasiocarpa ; Pseudotsuga menziesii ; Tsuga heterophylla ; Tsuga mertensianaSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Vesicles and hyphae typical of vesicular-arbuscular mycorrhizae (VAM) were common in seedlings of Pseudotsuga menziesii, Abies lasiocarpa and Tsuga mertensiana growing in openings where herbaceous hosts of these fungi were common. Seedlings of A. lasiocarpa, Tsuga heterophylla, and T. mertensiana growing under closed forest canopies also had vesicles but at a much lower incidence than seedlings in the openings. The Pinaceae are generally assumed to be ectomycorrhizal, but Glomus-type colonizations occurred on the same seedlings as the ectomycorrhizae. The ecological significance of abundant VAM-type endophytes in otherwise ectomycorrhizal hosts deserves comprehensive study.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1432-1890Keywords: Key words Ectomycorrhizae ; Glacier ; Succession ; Chronosequence ; Alnus ; Populus ; PiceaSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Ectomycorrhiza (EM) formation on plant roots in successional communities may vary with plant species, plant age, and age of vegetation after disturbance. To evaluate differences in mycorrhizal fungus communities on roots of same-aged seedlings across a deglaciated chronosequence, indoor-grown bioassay plants of four dominant species Epilobium latifolium L. (dwarf fireweed), Populus balsamifera ssp. trichocarpa (Torr.&Gray) Hult. (black cottonwood), Alnus sinuata (Regel) Rydb. (Sitka alder), and Picea sitchensis (Bong.) Carr. (Sitka spruce) were transplanted into five successional stages (Barren, Isolated Plant, Patchy, Alder, and Cottonwood) following deglaciation near Exit Glacier, Alaska. The species were selected for their successional status and mycorrhiza formation potential [EM or arbuscular mycorrhiza (AM) or both]. Seedlings were transplanted in June 1992, and half were harvested at the ends of the two subsequent growing seasons. The EM communities on P. balsamifera differed across the chronosequence while those of the other species did not. Morphotype B dominated the EM on P. balsamifera after the Barren stage, and the greatest EM colonization was in the Isolated Plant and Patchy stages. No AM were found. The EM observed on even-aged seedlings in this study were a subset of the EM found on naturally occurring plants (seedlings to mature trees) in a prior study, and some were common to multiple plant species. Most plant growth responses were not significant across stages or were inconsistent among plant species.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1573-5036Source: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Summary Nitrate-reducing capability was demonstrated for root segments of red alder and, at more than twice that rate, for alder nodules. Root segments of Douglas-fir failed to reduce nitrate despite various treatments designed to induce such activity. The reported response of Douglas-fir to nitrate fertilizer may be ascribed either to microbial assimilation of nitrate ions with subsequent liberation of ammonium in the soil or to nitrate assimilation by fungi that form mycorrhizae with Douglas-fir roots.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1432-136XKeywords: Key words Nutrition ; Mycophagy ; Fungi ; Voles ; SquirrelsSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract We evaluated the nutritional value of sporocarps of Rhizopogon vinicolor, a common hypogeous fungus in the coniferous forests of North America, for two small mammal species: the Californian red-backed vole (Clethrionomys californicus) and the northern flying squirrel (Glaucomys sabrinus). Although the nitrogen concentration of sporocarps was high, much of it was in non-protein form or associated with cell walls, suggesting that it may be of low nutritional value or protected from mammalian digestive enzymes. Sporocarps also had high concentrations of cell wall constituents, indicating low availability of digestible energy. When fed a diet of this fungus alone in a controlled feeding experiment both mammal species lost a small amount of body mass. Digestibilities of dry matter, nitrogen, cell wall constituents and energy from sporocarps by both species were lower than the digestibilities of other food types by other similarly sized small mammals. Red-backed voles digested the various components of sporocarps at least as well as the flying squirrels, even though they were almost six-fold smaller in body mass. This observation supports the notion that red-backed voles, like other microtine rodents, have morphological and physiological adaptations of the digestive system that are postulated to permit greater digestion of fibrous diets than predicted on the basis of body size. Despite this, our results re-affirm previous conclusions that hypogeous fungi are only of moderate nutritional value for most small, hindgut-fermenting mammals. Future studies should focus on the importance of mixed-species of fungi in the diet of small mammalian mycophagists.Type of Medium: Electronic ResourceURL: