Search Results - (Author, Cooperation:J. Shorter)
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1H. J. Kim ; N. C. Kim ; Y. D. Wang ; E. A. Scarborough ; J. Moore ; Z. Diaz ; K. S. MacLea ; B. Freibaum ; S. Li ; A. Molliex ; A. P. Kanagaraj ; R. Carter ; K. B. Boylan ; A. M. Wojtas ; R. Rademakers ; J. L. Pinkus ; S. A. Greenberg ; J. Q. Trojanowski ; B. J. Traynor ; B. N. Smith ; S. Topp ; A. S. Gkazi ; J. Miller ; C. E. Shaw ; M. Kottlors ; J. Kirschner ; A. Pestronk ; Y. R. Li ; A. F. Ford ; A. D. Gitler ; M. Benatar ; O. D. King ; V. E. Kimonis ; E. D. Ross ; C. C. Weihl ; J. Shorter ; J. P. Taylor
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-03-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Amyotrophic Lateral Sclerosis/*genetics/metabolism/*pathology ; Animals ; Drosophila melanogaster/cytology/genetics/metabolism ; Female ; Frontotemporal Dementia/*genetics/metabolism/pathology ; HeLa Cells ; Heterogeneous-Nuclear Ribonucleoprotein Group A-B/*chemistry/genetics/*metabolism ; Humans ; Inclusion Bodies/genetics/metabolism/pathology ; Male ; Mice ; Molecular Sequence Data ; Muscular Dystrophies, Limb-Girdle/*genetics/metabolism/pathology ; Mutant Proteins/chemistry/*genetics/metabolism ; Mutation/*genetics ; Myositis, Inclusion Body/*genetics/metabolism/pathology ; Osteitis Deformans/*genetics/metabolism/pathology ; Peptide Termination Factors/chemistry/genetics/metabolism ; Prions/*chemistry/genetics/metabolism ; Protein Structure, Tertiary/genetics ; RNA/metabolism ; Saccharomyces cerevisiae Proteins/chemistry/genetics/metabolismPublished by: -
2Shorter, J. H. ; Kolb, C. E. ; Crill, P. M. ; Kerwin, R. A. ; Talbot, R. W. ; Hines, M. E. ; Harriss, R. C.
[s.l.] : Nature Publishing Group
Published 1995Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Methyl bromide is the most abundant gaseous bromine species in the atmosphere, with an average atmospheric mixing ratio in the Northern Hemisphere of 10-15 parts per trillion by volume (p.p.t.v.), with values in the Southern Hemisphere 15-30% lower1 5. Important atmospheric sources for ...Type of Medium: Electronic ResourceURL: -
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ISSN: 0004-8402Topics: PhilosophyNotes: DISCUSSIONURL: -
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ISSN: 0004-8402Topics: PhilosophyURL: -
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ISSN: 0004-8402Topics: PhilosophyNotes: DISCUSSIONURL: -
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ISSN: 0004-8402Topics: PhilosophyNotes: REVIEWSURL: -
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ISSN: 0307-4412Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0307-4412Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0169-7439Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0169-7439Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0169-7439Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0160-9327Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
14Robbins, T. W. ; Semple, J. ; Kumar, R. ; Truman, M. I. ; Shorter, J. ; Ferraro, A. ; Fox, B. ; McKay, G. ; Matthews, K.
Springer
Published 1997Staff ViewISSN: 1432-2072Keywords: Key words Scopolamine ; Diazepam ; Memory ; Learning ; Benzodiazepine ; Acetylcholine ; Arousal ; Attention ; DementiaSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Two experiments examined dose-related effects of 200, 400 and 600 μg scopolamine (n = 24, SC) and 5 and 10 mg diazepam (n = 6, PO) on parallel tests of visual memory and learning taken from the CANTAB battery. Scopolamine significantly impaired accuracy of performance on a delayed matching to sample test of visual recognition memory in a dose-and delay-dependent manner, but had only marginal decremental effects on a test of visuospatial paired associates learning. Scopolamine significantly lengthened decision times in a visual search matching to sample task at the 400 and 600 μg doses, without significantly affecting accuracy. The drug also impaired performance on tests of spatial (on accuracy and response time measures) and pattern (on response time only) memory. Most of the deleterious effects on scopolamine were removed by covariance analyses with indices of subjective sedation, but the effects of delayed matching accuracy and latency remained. By contrast, diazepam significantly impaired paired associates learning but affected delayed matching to sample in a delay-independent manner. These results suggest that scopolamine can produce selective deficits in tests of short-term visual recognition memory which do not depend on overall impairments in arousal and which contrast with deficits in visual associative learning produced by diazepam. They have implications for the pharmacological modelling of dementia and memory disorders in man and for the neurochemical substrates of the short-term recognition memory and associative learning for visual stimuli.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1574-9274Source: Springer Online Journal Archives 1860-2000Topics: PhilosophyType of Medium: Electronic ResourceURL: