Search Results - (Author, Cooperation:J. Schulz)
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1Amy J. Schulz; Graciela B. Mentz; Natalie Sampson; Melanie Ward; J. Timothy Dvonch; Ricardo de Majo; Barbara A. Israel; Angela G. Reyes; Donele Wilkins
MDPI Publishing
Published 2018Staff ViewPublication Date: 2018-06-09Publisher: MDPI PublishingPrint ISSN: 1661-7827Electronic ISSN: 1660-4601Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicinePublished by: -
2Staff View
Publication Date: 2018-05-10Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
3Staff View
Publication Date: 2018-03-27Publisher: American Heart Association (AHA)Print ISSN: 0039-2499Electronic ISSN: 1524-4628Topics: MedicineKeywords: Cerebrovascular Disease/Stroke, Transient Ischemic Attack (TIA)Published by: -
4Staff View
Publication Date: 2018-09-11Publisher: MDPI PublishingPrint ISSN: 1661-7827Electronic ISSN: 1660-4601Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicinePublished by: -
5Staff View
Publication Date: 2018-03-07Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
6M. Canedo-Arguelles ; C. P. Hawkins ; B. J. Kefford ; R. B. Schafer ; B. J. Dyack ; S. Brucet ; D. Buchwalter ; J. Dunlop ; O. Fror ; J. Lazorchak ; E. Coring ; H. R. Fernandez ; W. Goodfellow ; A. L. Achem ; S. Hatfield-Dodds ; B. K. Karimov ; P. Mensah ; J. R. Olson ; C. Piscart ; N. Prat ; S. Ponsa ; C. J. Schulz ; A. J. Timpano
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-02-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
7Staff View
Publication Date: 2018-10-03Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
8Nevo, O., Razafimandimby, D., Jeffrey, J. A. J., Schulz, S., Ayasse, M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-10-04Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
9T. J. Schulz ; P. Huang ; T. L. Huang ; R. Xue ; L. E. McDougall ; K. L. Townsend ; A. M. Cypess ; Y. Mishina ; E. Gussoni ; Y. H. Tseng
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-03-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adipose Tissue, Brown/*cytology/innervation/metabolism ; Adipose Tissue, White/*cytology/metabolism ; Animals ; Body Temperature ; Body Temperature Regulation ; Bone Morphogenetic Protein Receptors, Type I/genetics/metabolism ; Bone Morphogenetic Proteins/genetics/*metabolism ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Energy Metabolism ; Mice ; *Signal Transduction ; Stem Cells/cytologyPublished by: -
10Staff View
Publication Date: 2018-07-24Publisher: MDPI PublishingPrint ISSN: 1661-7827Electronic ISSN: 1660-4601Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicinePublished by: -
11Verena Coleman; Piangkwan Sa-Nguanmoo; Jeannette Koenig; Tim J. Schulz; Tilman Grune; Susanne Klaus; Anna P. Kipp; Mario Ost
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-07-24Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2045-2322Topics: Natural Sciences in GeneralPublished by: -
12H. N. Chapman ; P. Fromme ; A. Barty ; T. A. White ; R. A. Kirian ; A. Aquila ; M. S. Hunter ; J. Schulz ; D. P. DePonte ; U. Weierstall ; R. B. Doak ; F. R. Maia ; A. V. Martin ; I. Schlichting ; L. Lomb ; N. Coppola ; R. L. Shoeman ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; P. Holl ; M. Liang ; M. Barthelmess ; C. Caleman ; S. Boutet ; M. J. Bogan ; J. Krzywinski ; C. Bostedt ; S. Bajt ; L. Gumprecht ; B. Rudek ; B. Erk ; C. Schmidt ; A. Homke ; C. Reich ; D. Pietschner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; M. Messerschmidt ; J. D. Bozek ; S. P. Hau-Riege ; M. Frank ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; G. J. Williams ; J. Hajdu ; N. Timneanu ; M. M. Seibert ; J. Andreasson ; A. Rocker ; O. Jonsson ; M. Svenda ; S. Stern ; K. Nass ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; K. E. Schmidt ; X. Wang ; I. Grotjohann ; J. M. Holton ; T. R. Barends ; R. Neutze ; S. Marchesini ; R. Fromme ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; I. Andersson ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; J. C. Spence
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Crystallography, X-Ray/instrumentation/*methods ; Lasers ; Models, Molecular ; Nanoparticles/*chemistry ; Nanotechnology/instrumentation/*methods ; Photosystem I Protein Complex/*chemistry ; Protein Conformation ; Time Factors ; X-RaysPublished by: -
13M. M. Seibert ; T. Ekeberg ; F. R. Maia ; M. Svenda ; J. Andreasson ; O. Jonsson ; D. Odic ; B. Iwan ; A. Rocker ; D. Westphal ; M. Hantke ; D. P. DePonte ; A. Barty ; J. Schulz ; L. Gumprecht ; N. Coppola ; A. Aquila ; M. Liang ; T. A. White ; A. Martin ; C. Caleman ; S. Stern ; C. Abergel ; V. Seltzer ; J. M. Claverie ; C. Bostedt ; J. D. Bozek ; S. Boutet ; A. A. Miahnahri ; M. Messerschmidt ; J. Krzywinski ; G. Williams ; K. O. Hodgson ; M. J. Bogan ; C. Y. Hampton ; R. G. Sierra ; D. Starodub ; I. Andersson ; S. Bajt ; M. Barthelmess ; J. C. Spence ; P. Fromme ; U. Weierstall ; R. Kirian ; M. Hunter ; R. B. Doak ; S. Marchesini ; S. P. Hau-Riege ; M. Frank ; R. L. Shoeman ; L. Lomb ; S. W. Epp ; R. Hartmann ; D. Rolles ; A. Rudenko ; C. Schmidt ; L. Foucar ; N. Kimmel ; P. Holl ; B. Rudek ; B. Erk ; A. Homke ; C. Reich ; D. Pietschner ; G. Weidenspointner ; L. Struder ; G. Hauser ; H. Gorke ; J. Ullrich ; I. Schlichting ; S. Herrmann ; G. Schaller ; F. Schopper ; H. Soltau ; K. U. Kuhnel ; R. Andritschke ; C. D. Schroter ; F. Krasniqi ; M. Bott ; S. Schorb ; D. Rupp ; M. Adolph ; T. Gorkhover ; H. Hirsemann ; G. Potdevin ; H. Graafsma ; B. Nilsson ; H. N. Chapman ; J. Hajdu
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Electrons ; Hot Temperature ; Lasers ; Mimiviridae/*chemistry ; Photons ; Time Factors ; X-Ray Diffraction/*instrumentation/*methods ; X-RaysPublished by: -
14N. D. Loh ; C. Y. Hampton ; A. V. Martin ; D. Starodub ; R. G. Sierra ; A. Barty ; A. Aquila ; J. Schulz ; L. Lomb ; J. Steinbrener ; R. L. Shoeman ; S. Kassemeyer ; C. Bostedt ; J. Bozek ; S. W. Epp ; B. Erk ; R. Hartmann ; D. Rolles ; A. Rudenko ; B. Rudek ; L. Foucar ; N. Kimmel ; G. Weidenspointner ; G. Hauser ; P. Holl ; E. Pedersoli ; M. Liang ; M. S. Hunter ; L. Gumprecht ; N. Coppola ; C. Wunderer ; H. Graafsma ; F. R. Maia ; T. Ekeberg ; M. Hantke ; H. Fleckenstein ; H. Hirsemann ; K. Nass ; T. A. White ; H. J. Tobias ; G. R. Farquar ; W. H. Benner ; S. P. Hau-Riege ; C. Reich ; A. Hartmann ; H. Soltau ; S. Marchesini ; S. Bajt ; M. Barthelmess ; P. Bucksbaum ; K. O. Hodgson ; L. Struder ; J. Ullrich ; M. Frank ; I. Schlichting ; H. N. Chapman ; M. J. Bogan
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aerosols/*analysis/*chemistry ; Amino Acids/chemistry ; Electrons ; *Fractals ; Lasers ; *Mass Spectrometry ; *Motion ; Nanoparticles ; Particle Size ; Proteins/chemistry ; Solvents/chemistry ; Soot/*analysis/*chemistry ; Vibration ; X-Ray DiffractionPublished by: -
15Staff View
Type of Medium: OnlinePublication Date: 2015Keywords: Kompetenz ; Unsicherheit ; Test ; Strukturmodell ; Messung ; MessfehlerIn: Bernholt, Sascha (Hrsg.), Heterogenität und Diversität-Vielfalt der Voraussetzungen im naturwissenschaftlichen Unterricht., Kiel: IPN (2015), S. 669-671, 978-3-89088-362-5Language: German -
16Simons, M. ; Beinroth, S. ; Gleichmann, M. ; Liston, P. ; Korneluk, R. G. ; MacKenzie, A. E. ; Bähr, M. ; Klockgether, T. ; Robertson, G. S. ; Weller, M. ; Schulz, J. B.
Oxford UK : Blackwell Science Ltd.
Published 1999Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract : The inhibitor of apoptosis (IAP) family of anti-apoptoticgenes, originally discovered in baculovirus, exists in animals ranging frominsects to humans. Here, we investigated the ability of IAPs to suppress celldeath in both a neuronal model of apoptosis and excitotoxicity. Cerebellargranule neurons undergo apoptosis when switched from 25 to 5 mMpotassium, and excitotoxic cell death in response to glutamate. We examinedthe endogenous expression of four members of the IAP family, Xchromosome-linked IAP (XIAP), rat IAP1 (RIAP1), RIAP2, and neuronal apoptosisinhibitory protein (NAIP), by semiquantitative reverse PCR and immunoblotanalysis in cultured cerebellar granule neurons. Cerebellar granule neuronsexpress significant levels of RIAP2 mRNA and protein, but expression of RIAP1,NAIP, and XIAP was not detected. RIAP2 mRNA content and protein levels did notchange when cells were switched from 25 to 5 mM potassium. Todetermine whether ectopic expression of IAP influenced neuronal survival afterpotassium withdrawal or glutamate exposure, we used recombinant adenoviralvectors to target XIAP, human IAP1 (HIAP1), HIAP2, and NAIP into cerebellargranule neurons. We demonstrate that forced expression of IAPs efficientlyblocked potassium withdrawal-inducedN-acetly-Asp-Glu-Val-Asp-specific caspase activity and reduced DNAfragmentation. However, neurons were only protected from apoptosis up to 24 hafter potassium withdrawal, not at later time points suggesting that IAPSdelay but do not block apoptosis in cerebellar granule neurons. In contrast,treatment with 100 μM or 1 mM glutamate did not induce caspase activity and adenoviral-mediated expression of IAPs had no influence on subsequent excitotoxic cell death.Type of Medium: Electronic ResourceURL: -
17Foister, J. ; Tacke, U. ; Krebs, H. ; Streckert, H. J. ; Werchau, H. ; Bergmann, R. L ; Schulz, J. ; Lau, S. ; Wahn, U.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1399-3038Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Our aim was to study the influence of infection with the respiratory syncytial virus (RSV) in non-hospitalized infants on sensitization to aeroallergens and the early manifestation of atopy. Six hundert and nine infants from the prospective German Multicenter Cohort Study on Atopy were included, 38% of whom had an elevated atopic risk. RSV IgG and IgM antibodies were tested by ELISA with gradient purified RSV antigen. Specific IgE against mites, cat dandruff, birch and grass pollens and relevant nutritional antigens were tested with CAP-RAST-FEIA (Pharmacia, Sweden). Of the cord sera 99% were positive for RSV-IgG, 44. 7% at one year and 64. 2% (n=265) at two years of age. The positivity rate after 12 months varied with the season of birth, the number of siblings and the degree of exposure to tobacco smoke; and correlated closely with attacks of wheezing during infancy. Twenty (2. 8%) children were found to be sensitized against at least one aeroallergen at one year, and 28 (10. 5%) at two years. By the first birthday, mite sensitization (n=3) could only be seen in the RSV-infected children; grass pollen sensitization (n=9) was associated with RSV seropositivity (logistic regression model including the confounders mentioned above: with RSV IgG p=0.04 〉 and IgM p=0.0006), as was birch sensitization (n=5) with RSV IgM (p=0.009). No such differences could be detected at two years. No correlation of RSV seropositivity to any allergic manifestation could be found. We conclude, that it is only in the first year of life, that RSV infection plays a significant role in promoting sensitization against aeroallergens, which do not at this time produce allergic symptoms.Type of Medium: Electronic ResourceURL: -
18Breit, S. ; Lessmann, L. ; Benazzouz, A. ; Schulz, J. B.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Recent data suggest a role for the pedunculopontine nucleus (PPN) in the pathophysiology of Parkinson's disease. Although there is anatomical evidence that the PPN and the basal ganglia are reciprocally connected, the functional importance of these connections is poorly understood. Lesioning of the PPN was shown to induce akinesia in primates, whereas in the 6-hydroxydopamine rat model the PPN was found to be hyperactive. As both nigrostriatal dopamine depletion and lesioning of the PPN were shown to induce akinesia and parkinsonism, the present study was performed in order to investigate the changes in neuronal activity of the subthalamic nucleus (STN) and the substantia nigra pars reticulata (SNr) after unilateral ibotenic acid lesioning of the PPN and after unilateral 6-hydroxydopamine lesioning of the substantia nigra pars compacta (SNc). The firing rate of STN neurones significantly increased from 10.2 ± 6.2 (mean ± SD) to 14.6 ± 11.7 spikes/s after lesion of the PPN and to 18.6 ± 14.5 spikes/s after lesion of the SNc. The activity of the SNr significantly increased from 19.6 ± 10.5 to 28.7 ± 13.4 spikes/s after PPN lesioning and to 23.5 ± 10.8 spikes/s after SNc lesioning. Furthermore, PPN lesion decreased the number of spontaneously firing dopaminergic SNc cells, while having no effect on their firing rate. The results of our study show that lesion of the PPN leads to hyperactivity of the STN and SNr, similar to the changes induced by lesion of the SNc. Moreover, the decreased activity of SNc cells observed after PPN lesion might be at the origin of activity changes in the STN and SNr.Type of Medium: Electronic ResourceURL: -
19Gleichmann, M. ; Buchheim, G. ; El-Bizri, H. ; Yokota, Y. ; Klockgether, T. ; Kügler, S. ; Bähr, M. ; Weller, M. ; Schulz, J. B.
Oxford, UK : Blackwell Science, Ltd
Published 2002Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Inhibitor-of-differentiation 2 (Id2) belongs to a family of transcriptional modulators that are characterized by a helix loop helix region but lack the basic amino acid domain. During development, Id2 antagonizes differentiation mediated by the retinoblastoma protein, probably by scavenging downstream E-box basic helix-loop-helix proteins. Here, using differential display RT-PCR, we identify Id2 as an induced gene during serum and potassium deprivation-induced apoptosis of cerebellar granule neurons. Consistent with a biological role for induced Id2 messenger RNA and protein expression in neuronal cell death, expression of Id2 antisense RNA, or targeted deletion of the Id2 gene in neurons from Id2 knock-out mice, protect from apoptosis. Further, gene transfer- mediated overexpression of Id2 induces neuronal cell death both in high potassium and low potassium conditions. Thus, the present study defines a role for Id2 in the modulation of neuronal apoptosis.Type of Medium: Electronic ResourceURL: -
20Bergmann, R. L. ; Forster, J. ; Schulz, J. ; Bergmann, K. E. ; Bauer, C. P. ; Wahn, U.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1399-3038Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In order to identify newborns at risk for atopic diseases, we developed a family questionnaire and selected specific answers which were suitable to identify atopic family members. The validity of the questionnaire was evaluated by the Phadiatop lest results of 793 mothers and 353 fathers. As both screening instruments do not measure the same, the Phadiatop test identifies scnsitization to inhalant allergens and the history reflects the clinical manifestation of atopic disease, the agreement between sensitization and manifestation is incomplete. Sensitivity and specificity of the questionnaire screening conditions to reproduce the Phadiotop lest result was 64% and 84% for mothers, and 58% and 88% for fathers, respectively. The relative risk for lifetime prevalence of atopic manifestations in Phadiatop positive over negative mothers was calculated to be 3. 88 (95% confidence interval = 3. 12 to 4. 81), and for Phadiatop positive over negative fathers to amount 4. 84 (95% confidence interval 3. 25 to 7. 23). A few relevant answers of 20 were identified by logistic regression analysis to predict the Phadiatop test result nearly, as well as the total questionnaire.Type of Medium: Electronic ResourceURL: