Search Results - (Author, Cooperation:J. S. Arthur)
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1Z. Zhou ; A. T. Tang ; W. Y. Wong ; S. Bamezai ; L. M. Goddard ; R. Shenkar ; S. Zhou ; J. Yang ; A. C. Wright ; M. Foley ; J. S. Arthur ; K. J. Whitehead ; I. A. Awad ; D. Y. Li ; X. Zheng ; M. L. Kahn
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: ADAM Proteins/metabolism ; Animals ; Animals, Newborn ; Carrier Proteins/genetics/metabolism ; Disease Models, Animal ; Endothelial Cells/enzymology/*metabolism ; Female ; Hemangioma, Cavernous, Central Nervous System/etiology/*metabolism/pathology ; Humans ; Kruppel-Like Transcription Factors/deficiency/*metabolism ; MAP Kinase Kinase Kinase 3/deficiency/*metabolism ; *MAP Kinase Signaling System ; Male ; Mice ; Protein Binding ; rho GTP-Binding Proteins/metabolismPublished by: -
2J. Park ; I. Al-Ramahi ; Q. Tan ; N. Mollema ; J. R. Diaz-Garcia ; T. Gallego-Flores ; H. C. Lu ; S. Lagalwar ; L. Duvick ; H. Kang ; Y. Lee ; P. Jafar-Nejad ; L. S. Sayegh ; R. Richman ; X. Liu ; Y. Gao ; C. A. Shaw ; J. S. Arthur ; H. T. Orr ; T. F. Westbrook ; J. Botas ; H. Y. Zoghbi
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-05-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Animals ; Animals, Genetically Modified ; Ataxin-1 ; Ataxins ; Cell Line, Tumor ; Disease Models, Animal ; Down-Regulation/drug effects ; Drosophila melanogaster/genetics/*metabolism ; Female ; Humans ; MAP Kinase Signaling System/drug effects ; Male ; Mice ; Mitogen-Activated Protein Kinases/*metabolism ; Molecular Sequence Data ; Molecular Targeted Therapy ; Nerve Tissue Proteins/chemistry/genetics/*metabolism/*toxicity ; Nuclear Proteins/chemistry/genetics/*metabolism/*toxicity ; Phosphorylation ; Protein Stability/drug effects ; Ribosomal Protein S6 Kinases, 90-kDa/deficiency/genetics/*metabolism ; Spinocerebellar Ataxias/*metabolism/*pathology ; Transgenes ; ras Proteins/*metabolismPublished by: -
3Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P., Cohen, P.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-11-20Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
4Staff View
ISSN: 1600-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract Many distributions of dental variables exhibit positive skew and variance heterogeneity. Although the use of parametric tests on data with these disturbances usually does not pose a problem with respect to alpha error level, transformation of data sometimes increases power. Occasionally one or both of these expectations do not hold and it becomes problematic as to whether data should be transformed and which analyses should be considered valid. Simulated dental trials were conducted on independent samples (n= 25 per group) drawn from exponential distributions with the same or different population means. t-tests on raw, log, and square root transformed data; the Mann-Whitney-Wilcoxon ranking test; and a randomization test, all exhibited satisfactory levels of alpha error but the randomization test exhibited the greatest power followed closely by the t-test on raw scores. The present results demonstrate that the log transformation does not increase power for all forms of positively skewed data. Randomization tests, not being subject to normality and variance homogeneity assumptions, may yield greater confidence in validity in these cases. Some implications for analytical strategy are discussed.Type of Medium: Electronic ResourceURL: