Search Results - (Author, Cooperation:J. Ruel)
-
1M. McDonald ; M. Bayliss ; B. A. Benson ; R. J. Foley ; J. Ruel ; P. Sullivan ; S. Veilleux ; K. A. Aird ; M. L. Ashby ; M. Bautz ; G. Bazin ; L. E. Bleem ; M. Brodwin ; J. E. Carlstrom ; C. L. Chang ; H. M. Cho ; A. Clocchiatti ; T. M. Crawford ; A. T. Crites ; T. de Haan ; S. Desai ; M. A. Dobbs ; J. P. Dudley ; E. Egami ; W. R. Forman ; G. P. Garmire ; E. M. George ; M. D. Gladders ; A. H. Gonzalez ; N. W. Halverson ; N. L. Harrington ; F. W. High ; G. P. Holder ; W. L. Holzapfel ; S. Hoover ; J. D. Hrubes ; C. Jones ; M. Joy ; R. Keisler ; L. Knox ; A. T. Lee ; E. M. Leitch ; J. Liu ; M. Lueker ; D. Luong-Van ; A. Mantz ; D. P. Marrone ; J. J. McMahon ; J. Mehl ; S. S. Meyer ; E. D. Miller ; L. Mocanu ; J. J. Mohr ; T. E. Montroy ; S. S. Murray ; T. Natoli ; S. Padin ; T. Plagge ; C. Pryke ; T. D. Rawle ; C. L. Reichardt ; A. Rest ; M. Rex ; J. E. Ruhl ; B. R. Saliwanchik ; A. Saro ; J. T. Sayre ; K. K. Schaffer ; L. Shaw ; E. Shirokoff ; R. Simcoe ; J. Song ; H. G. Spieler ; B. Stalder ; Z. Staniszewski ; A. A. Stark ; K. Story ; C. W. Stubbs ; R. Suhada ; A. van Engelen ; K. Vanderlinde ; J. D. Vieira ; A. Vikhlinin ; R. Williamson ; O. Zahn ; A. Zenteno
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-08-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2J. D. Vieira ; D. P. Marrone ; S. C. Chapman ; C. De Breuck ; Y. D. Hezaveh ; A. Weibeta ; J. E. Aguirre ; K. A. Aird ; M. Aravena ; M. L. Ashby ; M. Bayliss ; B. A. Benson ; A. D. Biggs ; L. E. Bleem ; J. J. Bock ; M. Bothwell ; C. M. Bradford ; M. Brodwin ; J. E. Carlstrom ; C. L. Chang ; T. M. Crawford ; A. T. Crites ; T. de Haan ; M. A. Dobbs ; E. B. Fomalont ; C. D. Fassnacht ; E. M. George ; M. D. Gladders ; A. H. Gonzalez ; T. R. Greve ; B. Gullberg ; N. W. Halverson ; F. W. High ; G. P. Holder ; W. L. Holzapfel ; S. Hoover ; J. D. Hrubes ; T. R. Hunter ; R. Keisler ; A. T. Lee ; E. M. Leitch ; M. Lueker ; D. Luong-Van ; M. Malkan ; V. McIntyre ; J. J. McMahon ; J. Mehl ; K. M. Menten ; S. S. Meyer ; L. M. Mocanu ; E. J. Murphy ; T. Natoli ; S. Padin ; T. Plagge ; C. L. Reichardt ; A. Rest ; J. Ruel ; J. E. Ruhl ; K. Sharon ; K. K. Schaffer ; L. Shaw ; E. Shirokoff ; J. S. Spilker ; B. Stalder ; Z. Staniszewski ; A. A. Stark ; K. Story ; K. Vanderlinde ; N. Welikala ; R. Williamson
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-03-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Rebillard, G. ; Ruel, J. ; Nouvian, R. ; Saleh, H. ; Pujol, R. ; Dehnes, Y. ; Raymond, J. ; Puel, J. L. ; Devau, G.
Oxford, UK : Blackwell Science, Ltd
Published 2003Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In the cochlea, glutamate plays a major role in synaptic transmission between the inner hair cell and the primary auditory neurons. Extracellular glutamate concentration must be regulated to prevent excitotoxicity. This regulation is mediated by excitatory amino acid transporters, membrane proteins that remove glutamate from the synaptic cleft. In this study, we investigated the distribution and activity of three excitatory amino acid transporters subtypes in the guinea-pig cochlea: glutamate aspartate transporter, glutamate transporter and excitatory amino acid carrier. A partial messenger ribonucleic acid sequence was determined for each of these transporters, by polymerase chain reaction with degenerate primers, using guinea-pig brain complementary deoxyribonucleic acid as the template. Primers specific for each transporter were then designed and used to screen a dissected organ of Corti complementary deoxyribonucleic acid library. The cellular distribution of each transporter was examined by immunocytochemistry. We investigated the functional consequences of inhibiting glutamate uptake by recording cochlear potentials during intracochlear perfusion with either l-trans-pyrrolidine-2,4-dicarboxylic acid or dihydrokainate. At the end of the electrophysiological session, cochleas were processed for electron microscopy. Only the glutamate aspartate transporter messenger ribonucleic acid was detected in the organ of Corti. Consistently, glutamate aspartate transporter protein was detected in the inner hair cell-supporting cells and in the ganglion of Corti satellite cells. Glutamate transporter and excitatory amino acid carrier were found in the afferent auditory neurons. Only intracochlear perfusions with l-trans-pyrrolidine-2,4-dicarboxylic acid resulted in a dose-dependent decrease in the amplitude of the cochlear compound action potential, leaving cochlear microphonic potential unaffected. After l-trans-pyrrolidine-2,4-dicarboxylic acid perfusion, cochleas displayed a swelling of the afferent endings typical of excitotoxicity. [(–)1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-4,5-dihydro-3-methylcarbamyl-2,3-benzodiazepine], a selective α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist protects the cochlea against l-trans-pyrrolidine-2,4-dicarboxylic acid effect.Type of Medium: Electronic ResourceURL: -
4THIVOLET, J. ; MONIER, J. C. ; RUEL, J. P. ; RICHARD, M. H.
[s.l.] : Nature Publishing Group
Published 1967Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Fifty-seven Swiss/Giff mice were operated on within 12 h of birth by Dischlers method2. Just before the birth of the young the mothers received Librium in water. This treatment was continued for 1 week in order to reduce the likelihood of cannibalism. Control mice were subjected to sham-thymectomy. ...Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0911-6044Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesBiologyMedicineType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0911-6044Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesBiologyMedicineType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0028-3932Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0028-3932Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0028-3932Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0303-7207Keywords: brain ; protein phosphorylation ; thyroid hormonesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0303-7207Keywords: brain ; protein phosphorylation ; thyroid hormonesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
12Bandrauk, André D. ; Ruel, J. ; Zuo, Tao ; Yu, Hengtai
New York, NY : Wiley-Blackwell
Published 1997Staff ViewISSN: 0020-7608Keywords: Chemistry ; Theoretical, Physical and Computational ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Combinations of circularly polarized intense laser pulses (I≥1014 W/cm2) and intense magnetic fields (B≃107 gauss) are shown to lead to control of electron orbits in atoms and molecules. In particular, it is proposed to use such intense field experiments to produce high-order harmonic generation into the ultraviolet and X-ray regions. © 1997 John Wiley & Sons, Inc. Int J Quant Chem 64: 613-617, 1997Additional Material: 2 Ill.Type of Medium: Electronic Resource