Search Results - (Author, Cooperation:J. Rosner)

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  1. 1
    Staff View
    Publication Date:
    2012-04-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Breast Neoplasms/diagnosis/*genetics/*pathology ; Clone Cells/metabolism/pathology ; DNA Copy Number Variations/genetics ; DNA Mutational Analysis ; Disease Progression ; *Evolution, Molecular ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/genetics ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; INDEL Mutation/genetics ; Mutation/*genetics ; Point Mutation/genetics ; Precision Medicine ; Reproducibility of Results ; Sequence Analysis, RNA
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-12-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Breast Neoplasms/*genetics/*pathology/secondary ; Clone Cells/*metabolism/*pathology ; DNA Mutational Analysis ; Genome, Human/*genetics ; Genomics ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Mice ; Neoplasm Transplantation ; *Single-Cell Analysis ; Time Factors ; Transplantation, Heterologous ; *Xenograft Model Antitumor Assays/methods
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Cardinali, D. P. ; Rosner, J. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1971
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1971.tb03752.x

    Articles: DFG German National Licenses
  4. 4
    Martin, R. G. ; Gillette, W. K. ; Rosner, J. L.

    Oxford BSL : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    MarA and SoxS are closely related proteins (≈45% identical) that transcriptionally activate a common set of unlinked genes, resulting in multiple antibiotic and superoxide resistance in Escherichia coli. Both proteins bind as monomers to a 20 bp degenerate asymmetric recognition sequence, the ‘marbox’, located upstream of the promoter. However, the proteins differ widely in the extents to which they activate particular promoters, with the consequence that overexpression of SoxS leads to greater superoxide resistance than does overexpression of MarA. This ‘discrimination’ between activators by promoters was demonstrated in vivo, using promoters fused to lacZ, and in vitro, using purified RNA polymerase, promoter DNA and MarA or SoxS. The marbox was found to be a critical element in discrimination by in vivo and in vitro assays of hybrid promoters containing the marbox from one gene and the core promoter from another. Furthermore, by sequential mutation of its marbox, a promoter that discriminated 35-fold in favour of SoxS was converted into one that did not discriminate. The relative activation of a promoter by MarA or SoxS was paralleled by the relative binding of the two activators to the promoter's marbox as assayed by band shift experiments. Thus, differential recognition of closely related marbox sequences by the closely related activators is the primary basis for promoter discrimination. Discrimination enables the cell to customize its response to the stresses that trigger synthesis of the activators.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2958.2000.01732.x

    Articles: DFG German National Licenses
  5. 5
    Franklin, R.M. ; Rosner, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0926-6550
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0926-6550(62)90245-1

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    0022-4731
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-4731(76)90206-5

    Articles: DFG German National Licenses
  7. 7
    Freund, P.G.O. ; Waltz, R. ; Rosner, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(69)90231-4

    Articles: DFG German National Licenses
  8. 8
    Rachmeler, M. ; Gerhart, J. ; Rosner, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-3002
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-3002(61)90888-5

    Articles: DFG German National Licenses
  9. 9
    Franklin, R.M. ; Rosner, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-3002
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-3002(62)90960-5

    Articles: DFG German National Licenses
  10. 10
    Faiman, D. ; Rosner, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0370-2693(73)90054-3

    Articles: DFG German National Licenses
  11. 11
    Cardinali, D. P. ; Nagle, C. A. ; Rosner, J. M.
    Springer
    Published 1974
    Staff View
    ISSN:
    1420-9071
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Résumé Des homogénats de glande pineale de rat mâle métabolisèrent de la testostérone-C14 in vitro en œstradiol-C14 et en œstrone-C14. Les métabolites furent identifiés chiomatographiquement et dans le cas de l'œstradiol par recristallisation à activité spécifique constante. La conversion de la testostérone en œstradiol fut de 0.19–0.27% et en œstrone de 0.02–0.04%. Ces résultatsci indiquent que la pinéale ressemble à d'autres régions du cerveau soumises au contrôle de la sécrétion de gonadotropines.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01923703

    Articles: DFG German National Licenses
  12. 12
    Nagle, C. A. ; Cardinali, D. P. ; Rosner, J. M.
    Springer
    Published 1975
    Staff View
    ISSN:
    1420-9071
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Summary The incorporation of3H-leucine into neurohypophyseal proteins was measured in vitro, 24 h after the administration of a single dose of estradiol (0.3 μg) to castrated female rats. Estradiol treatment caused a significant increase of3H-leucine incoporation into proteins of the posterior lobe. The effects of estradiol depended largely upon time injection. Rats injected at 06.00 h, i.e., at the end of the dark period exhibited at 74% increase in protein synthesis, whereas rat injected at 14.00 h, i.e., at the middle of the light period only showed a 30% of increase.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02358898

    Articles: DFG German National Licenses
  13. 13
    Rosner, J. L. ; Guyer, M. S.
    Springer
    Published 1980
    Staff View
    ISSN:
    1617-4623
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Summary Tn9 is a transposable element in which a gene (cat) determining chloramphenicol resistance is flanked by directly repeated sequences that are homologous to the insertion sequence IS1. We show here that infection of Escherichia coli K12 (under Rec- Red- Int- conditions) with a λbio transducing phage carrying Tn9 results in the formation of λbio transductants as frequently as cat transductants (about 1 per 106 to 107 infected cells). Most of the λbio transductants do not carry cat, just as most of the cat transductants do not carry λbio. In spite of the absence of cat, the λbio prophage can transpose a second time, from the E. coli chromosome to different sites on an F′ gal plasmid. Analysis of the structure of the transposed λbio element, by restriction nuclease digestion and by electron microscopy, demonstrates that the integrated λbio prophage is flanked by directly repeated IS1 elements. We conclude that there is no genetic information for the ability to transpose encoded in the non-repeated portion of Tn9, i.e. that the directly repeated IS1 elements alone are responsible for Tn9 transposition.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00267219

    Articles: DFG German National Licenses
  14. 14
    Marom, G. ; Harel, H. ; Rosner, J.

    New York, NY [u.a.] : Wiley-Blackwell
    Published 1977
    Staff View
    ISSN:
    0021-8995
    Keywords:
    Chemistry ; Polymer and Materials Science
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Notes:
    Three types of fracture energies, i.e., for initiation, propagation, and the work of fracture, were measured for an ammonium perchlorate/polybutadiene composite propellant. The testing employed the “trouser leg” specimen configuration. The effect of an accelerated again process on these energy values was also investigated, showing that such a process ultimately results in a reduction in the fracture energies.
    Additional Material:
    4 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1002/app.1977.070210619

    Articles: DFG German National Licenses