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1H. F. Zheng ; V. Forgetta ; Y. H. Hsu ; K. Estrada ; A. Rosello-Diez ; P. J. Leo ; C. L. Dahia ; K. H. Park-Min ; J. H. Tobias ; C. Kooperberg ; A. Kleinman ; U. Styrkarsdottir ; C. T. Liu ; C. Uggla ; D. S. Evans ; C. M. Nielson ; K. Walter ; U. Pettersson-Kymmer ; S. McCarthy ; J. Eriksson ; T. Kwan ; M. Jhamai ; K. Trajanoska ; Y. Memari ; J. Min ; J. Huang ; P. Danecek ; B. Wilmot ; R. Li ; W. C. Chou ; L. E. Mokry ; A. Moayyeri ; M. Claussnitzer ; C. H. Cheng ; W. Cheung ; C. Medina-Gomez ; B. Ge ; S. H. Chen ; K. Choi ; L. Oei ; J. Fraser ; R. Kraaij ; M. A. Hibbs ; C. L. Gregson ; D. Paquette ; A. Hofman ; C. Wibom ; G. J. Tranah ; M. Marshall ; B. B. Gardiner ; K. Cremin ; P. Auer ; L. Hsu ; S. Ring ; J. Y. Tung ; G. Thorleifsson ; A. W. Enneman ; N. M. van Schoor ; L. C. de Groot ; N. van der Velde ; B. Melin ; J. P. Kemp ; C. Christiansen ; A. Sayers ; Y. Zhou ; S. Calderari ; J. van Rooij ; C. Carlson ; U. Peters ; S. Berlivet ; J. Dostie ; A. G. Uitterlinden ; S. R. Williams ; C. Farber ; D. Grinberg ; A. Z. LaCroix ; J. Haessler ; D. I. Chasman ; F. Giulianini ; L. M. Rose ; P. M. Ridker ; J. A. Eisman ; T. V. Nguyen ; J. R. Center ; X. Nogues ; N. Garcia-Giralt ; L. L. Launer ; V. Gudnason ; D. Mellstrom ; L. Vandenput ; N. Amin ; C. M. van Duijn ; M. K. Karlsson ; O. Ljunggren ; O. Svensson ; G. Hallmans ; F. Rousseau ; S. Giroux ; J. Bussiere ; P. P. Arp ; F. Koromani ; R. L. Prince ; J. R. Lewis ; B. L. Langdahl ; A. P. Hermann ; J. E. Jensen ; S. Kaptoge ; K. T. Khaw ; J. Reeve ; M. M. Formosa ; A. Xuereb-Anastasi ; K. Akesson ; F. E. McGuigan ; G. Garg ; J. M. Olmos ; M. T. Zarrabeitia ; J. A. Riancho ; S. H. Ralston ; N. Alonso ; X. Jiang ; D. Goltzman ; T. Pastinen ; E. Grundberg ; D. Gauguier ; E. S. Orwoll ; D. Karasik ; G. Davey-Smith ; A. V. Smith ; K. Siggeirsdottir ; T. B. Harris ; M. C. Zillikens ; J. B. van Meurs ; U. Thorsteinsdottir ; M. T. Maurano ; N. J. Timpson ; N. Soranzo ; R. Durbin ; S. G. Wilson ; E. E. Ntzani ; M. A. Brown ; K. Stefansson ; D. A. Hinds ; T. Spector ; L. A. Cupples ; C. Ohlsson ; C. M. Greenwood ; R. D. Jackson ; D. W. Rowe ; C. A. Loomis ; D. M. Evans ; C. L. Ackert-Bicknell ; A. L. Joyner ; E. L. Duncan ; D. P. Kiel ; F. Rivadeneira ; J. B. Richards
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-09-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bone Density/*genetics ; Bone and Bones/metabolism ; Disease Models, Animal ; Europe/ethnology ; European Continental Ancestry Group/genetics ; Exome/genetics ; Female ; Fractures, Bone/*genetics ; Gene Frequency/genetics ; Genetic Predisposition to Disease/genetics ; Genetic Variation/genetics ; Genome, Human/*genetics ; Genomics ; Genotype ; Homeodomain Proteins/*genetics ; Humans ; Mice ; Sequence Analysis, DNA ; Wnt Proteins/geneticsPublished by: -
2Erspamer, V. ; Go, V. L. W. ; Battey, J. F. ; Bloom, S. R. ; Mcdonald, T. J. ; Minamino, N. ; Negri, L. ; Reeve, J. R. ; Rivier, J. ; Spindel, E. R. ; Taché, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 0022-4545Topics: PsychologySociologyURL: -
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ISSN: 0005-2736Keywords: (E. coli) ; (Vesicular stomatitis virus) ; Membrane lipid ; Ultraviolet radiation protectionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
5PONTA, H. ; REEVE, J. N. ; PFENNIG-YEH, M. ; HIRSCH-KAUFFMANN, M. ; SCHWEIGER, M. ; HERRLICH, P.
[s.l.] : Nature Publishing Group
Published 1977Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] T7 produces approximately 10,000 times more plaques when plated on an F lawn of E. coli cells compared with F+ lawns. The plaques produced on an F+ lawn are irregular in size and do not contain selected mutant or host-cell-modified phage, as phages isolated from these plaques have no increased ...Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0009-8981Keywords: Calcium balance ; Osteoporosis ; Urinary hydroxyproline ; ^8^5SrSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0378-1119Keywords: T5 and pBR322::T5 recombinantsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0022-5193Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0378-4347Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
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ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
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ISSN: 1572-8838Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyElectrical Engineering, Measurement and Control TechnologyNotes: Abstract Electrochemical measurements were carried out simultaneously with acquisition of in situ STM images of copper electrodeposition at low cathodic overpotentials and subsequent dissolution from the underlying polycrystalline gold surfaces. The morphologies of the copper deposits were examined for correlation with features of the current-voltage diagram. Copper growth is by nucleation and formation of 3D islands. During the initial stages of bulk copper growth the potentials were fixed at selected values and a balance observed between formation of polycrystalline copper nuclei and of copper crystals. After the first cycle of copper deposition and dissolution the morphology of the polycrystalline gold surface had apparently changed into a recrystallized phase of a copper-gold alloy. At a given stage of the cycle the potential of the electrode was found to depend linearly on the tip potential. In a wide range of tip potentials the onset of copper deposition and end of dissolution showed a potential separation of 59 ± 5 mV indicating a single electron process.Type of Medium: Electronic ResourceURL: -
12Hesch, R. D. ; Heck, J. ; Delling, G. ; Keck, E. ; Reeve, J. ; Canzler, H. ; Schober, O. ; Harms, H. ; Rittinghaus, E. F.
Springer
Published 1988Staff ViewISSN: 1432-1440Keywords: Osteoporosis ; Parathyroid hormone ; Bone metabolismSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary In contrast to prevention, the therapy of manifest osteoporosis remains a clinically significant problem. So far all therapeutic attempts have yielded unsatisfying results. For this reason we have tried to achieve a positive bone balance by sequential stimulation and inhibition of the osseous metabolism. The therapy consisted of six 14-day courses with 400 units (1–38)hPTH per day and, in addition, starting with the 2nd week of PTH therapy, EHDP 5 mg per kg body weight per day for a total of 2 weeks. Already the initial therapeutic course resulted in a stimulation of decreased bone metabolism which could be documented by an increase in the calcium-47 accretion rate (six patients). An increase of the alkaline phosphatase could be noted (four patients); this, however, did not correlate with the calcium accretion. A positive calcium balance could, nonetheless, only be attained in four of eight patients within this period, while neither the alkaline phosphatase nor the kinetics would allow a prediction of this effect. Changes of the balance coincided with equal changes in the net calcium absorption. The urinary calcium excretion increased temporarily during the therapeutic phase. We were not able to detect an influence on the vitamin D metabolites. Histomorphometric studies did not demonstrate an increase in bone mass in the iliac creast after six therapeutic courses. Nevertheless, progressive deformations of vertebral bodies did not occur. We conclude that already after 2 weeks this therapeutic concept can lead to a stimulation of bone metabolism.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1432-0827Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1432-0827Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
15Milhaud, G. ; Christiansen, C. ; Gallagher, C. ; Reeve, J. ; Seeman, E. ; Chesnut, C. ; Parfitt, A.
Springer
Published 1983Staff ViewISSN: 1432-0827Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
16Masaryk, P. ; Lunt, M. ; Benevolenskaya, L. ; Cannata, J. ; Dequeker, J. ; Dohenhof, C. ; Falch, J. A. ; Felsenberg, D. ; Pols, H. A. P. ; Poor, G. ; Reid, D. M. ; Scheidt-Nave, C. ; Weber, K. ; O'Neill, T. ; Silman, A. J. ; Reeve, J.
Springer
Published 1998Staff ViewISSN: 1432-0827Keywords: Key words: Bone mineral density — Epidemiology — Osteoporosis — Menopause — Medication use.Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsNotes: Abstract: We have previously shown considerable between-center variation in bone mineral density (BMD) in the 13 EVOS centers that performed bone densitometry on their sex- and age-stratified population samples, after adjusting for weight and age. We have now investigated whether part of the between-center variability may be attributed to between-center variations in the use of medications. Information was collected from 2088 women and 1908 men at baseline on whether the subjects had ever been prescribed calcium, calcitonin, anabolic steroids, fluoride, vitamin D, or glucocorticoids and, for the women, whether they had ever used the oral contraceptive pill (OCP) or hormone replacement therapy (HRT). Each of these variables was fitted into a regression model adjusted for age, height, weight, and center. Only OCP and HRT significantly affected BMD. Those who had ever used OCPs had spinal BMD 0.029 g/cm2 greater than those who had never used them. Users of HRT had higher BMD than nonusers: 0.037 g/cm2 at the spine, 0.018 g/cm2 at the trochanter, and 0.018 g/cm2 at the femoral neck. As expected, there was a great variation between centers in the use of OCP and HRT, but there were no significant correlations between mean BMD at any site in a given center and the prevalence of OCP or HRT use in that center. The between-center variance in BMD at all three sites remained highly significant after adjusting for treatment (P 〈 0.001). We conclude that HRT and OCP use are associated with moderate increases in BMD. The geographical variability of BMD in Europe was not explained by treatment with pharmaceuticals.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0092-6566Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
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ISSN: 0167-0115Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0167-0115Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
20Grandt, D. ; Feth, F. ; Schimiczek, M. ; Michel, M. ; Schlicker, E. ; Rascher, W. ; Goebell, H. ; Eysselein, V. ; Reeve, J.
Amsterdam : ElsevierStaff ViewISSN: 0167-0115Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: