Search Results - (Author, Cooperation:J. R. Carlson)
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1Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2013-06-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Carbon Dioxide ; Drosophila Proteins/*physiology ; Drosophila melanogaster/*physiology ; Escape Reaction/*physiology ; Olfactory Pathways/*physiology ; Olfactory Receptor Neurons/*physiology ; Receptors, Ionotropic Glutamate/*physiology ; Sodium Channels/*physiology ; *Sodium Chloride ; Taste Perception/*physiologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2012-11-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anopheles gambiae/drug effects/physiology ; Carbon Dioxide/pharmacology ; Dose-Response Relationship, Drug ; Drosophila melanogaster/cytology/drug effects/physiology ; Female ; Neural Inhibition/drug effects/*physiology ; Olfactory Pathways/drug effects/*physiology ; Olfactory Receptor Neurons/cytology/drug effects/*metabolism ; Sensilla/cytology/drug effects/innervation/physiology ; Smell/drug effects/physiology ; *Synapses ; Synaptic Transmission/drug effectsPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1432-1351Keywords: Key words Olfaction ; Drosophila ; Antenna ; lozenge ; SensillaSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract The physiology and ultrastructure of the antenna in Drosophila melanogaster have been examined in wild-type and lozenge mutants. Scanning electron microscopy (SEM) of sensilla on the antennal surface has revealed that in the wild-type the basiconic sensilla contain linear arrays of pores connected by longitudinal furrows and transected by shorter furrows. Sensilla trichodea also are shown to have pores, as revealed by examining transverse sections by transmission electron microscopy (TEM); these data directly address a long-standing controversy. Coeloconic sensilla, previously described as “pit sensilla” and as “grooved” sensilla, are shown to rise directly from the antennal surface, as opposed to lying below the antennal surface in pits; the previously observed grooves correspond to the junctions between bundled, finger-like projections. This description of coeloconic sensilla is supported by analysis of lz mutants, in which the projections of coeloconic sensilla splay apart. Coeloconic sensilla are also shown to undergo duplication on the lz 3 antenna. Physiological recordings from the antenna show that responses to all odorants tested are severely decreased in lz mutants. Measurements made from different parts of the antenna show similar defects. Evidence is provided that both the physiological and ultrastructural defects map to the lz locus.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1432-1351Keywords: rdgB ; Maxillary palp ; Drosophila ; Electrophysiology ; OlfactionSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract We describe the kinetics of odorant response in the maxillary palp of Drosophila, and show that the rate of recovery from odorant stimulation is affected by mutation of the rdgB (retinal degeneration B) gene. We use immunocytochemistry to confirm that the rdgB gene product is expressed in the maxillary palp. rdgB has recently been shown to encode a protein with Ca2+-binding sites and sequence similarity to rat brain phosphatidylinositol transfer protein; it is located near the rhabdomeric membranes in photoreceptor cells, where it has been suggested to play a role in membrane transport. The delay in recovery kinetics that we observe in olfactory tissue may reflect a defect in membrane restoration at the conclusion of the olfactory transduction cascade. The use of common molecules in the physiology of two olfactory organs, and in both visual and olfactory physiology, is discussed.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesCarlson, J. R. ; Sullivan, P. S. ; Harry, D. J. ; Stork, M. A. ; Thorton, S. A. ; DuPont, H. L.
Springer
Published 1988Staff ViewISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract An enzyme immunoassay (EIA) was developed for direct detection ofGiardia lamblia antigens in fecal specimens. The EIA was evaluated by testing specimens from 1,331 subjects in the USA and Egypt. For the 353 specimens from human subjects in the USA there was a 97% overall agreement between the results of the EIA and direct microscopic examination, yielding a sensitivity and specificity of 92% and 99% respectively. Due to adverse field conditions the EIA did not perform as well in the specimens collected and tested in Egypt. The sensitivity and specificity for 585 human specimens from Egypt were 74% and 97% respectively.Type of Medium: Electronic ResourceURL: