Search Results - (Author, Cooperation:J. R. Brown)
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1Latest Papers from Table of Contents or Articles in PressPupo, G., Ibba, F., Ascough, D. M. H., Vicini, A. C., Ricci, P., Christensen, K. E., Pfeifer, L., Morphy, J. R., Brown, J. M., Paton, R. S., Gouverneur, V.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-05-11Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: ChemistryPublished by: -
2Latest Papers from Table of Contents or Articles in PressB. Cederwall ; F. G. Moradi ; T. Back ; A. Johnson ; J. Blomqvist ; E. Clement ; G. de France ; R. Wadsworth ; K. Andgren ; K. Lagergren ; A. Dijon ; G. Jaworski ; R. Liotta ; C. Qi ; B. M. Nyako ; J. Nyberg ; M. Palacz ; H. Al-Azri ; A. Algora ; G. de Angelis ; A. Atac ; S. Bhattacharyya ; T. Brock ; J. R. Brown ; P. Davies ; A. Di Nitto ; Z. Dombradi ; A. Gadea ; J. Gal ; B. Hadinia ; F. Johnston-Theasby ; P. Joshi ; K. Juhasz ; R. Julin ; A. Jungclaus ; G. Kalinka ; S. O. Kara ; A. Khaplanov ; J. Kownacki ; G. La Rana ; S. M. Lenzi ; J. Molnar ; R. Moro ; D. R. Napoli ; B. S. Singh ; A. Persson ; F. Recchia ; M. Sandzelius ; J. N. Scheurer ; G. Sletten ; D. Sohler ; P. A. Soderstrom ; M. J. Taylor ; J. Timar ; J. J. Valiente-Dobon ; E. Vardaci ; S. Williams
Nature Publishing Group (NPG)
Published 2010Staff ViewPublication Date: 2010-12-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2014-11-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: *Climate Change ; *El Nino-Southern Oscillation ; *Models, TheoreticalPublished by: -
4Latest Papers from Table of Contents or Articles in PressN. Kwiatkowski ; T. Zhang ; P. B. Rahl ; B. J. Abraham ; J. Reddy ; S. B. Ficarro ; A. Dastur ; A. Amzallag ; S. Ramaswamy ; B. Tesar ; C. E. Jenkins ; N. M. Hannett ; D. McMillin ; T. Sanda ; T. Sim ; N. D. Kim ; T. Look ; C. S. Mitsiades ; A. P. Weng ; J. R. Brown ; C. H. Benes ; J. A. Marto ; R. A. Young ; N. S. Gray
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Core Binding Factor Alpha 2 Subunit/metabolism ; Cyclin-Dependent Kinases/antagonists & inhibitors ; Cysteine/metabolism ; Enzyme Inhibitors/*pharmacology ; Gene Expression Regulation, Neoplastic/*drug effects ; Humans ; Jurkat Cells ; Phenylenediamines/*pharmacology ; Phosphorylation/drug effects ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*enzymology ; Pyrimidines/*pharmacologyPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-04-27Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Free Research ArticlesPublished by: -
6Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-26Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: How I Treat, Free Research Articles, Lymphoid Neoplasia, Clinical Trials and ObservationsPublished by: -
7Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-12-07Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Free Research ArticlesPublished by: -
8Articles: DFG German National LicensesCAMPION, M. J. ; BROWN, J. R. ; MCCANCE, D. J. ; ATIA, W. ; EDWARDS, R. ; CUZICK, J. ; SINGER, A.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. The psychosexual sequelae of diagnosis and treatment of pre-invasive cervical atypia were assessed in three groups of women. The first group included 30 women referred to a colposcopy clinic with an abnormal cervical smear indicating cervical intraepithelial neoplasia (CIN), the second comprised 50 women who were traced as sexual partners of men with penile human papillomavirus (HPV) infection; 26 of them had histologically proven cervical atypia and 24 had no such evidence. The third group included 25 women traced as partners of men with non-specific urethritis and who did not have cervical disease. Before and after questionnaires assessed six aspects of sexual behaviour and responses before diagnosis and 6 months after treatment in women with cervical atypia. These were compared with answers given by women investigated and treated, if necessary, as partners of men with sexually transmitted disease (control group). There were statistically significant adverse psychosexual sequelae associated with diagnosis and treatment of pre-invasive cervical epithelial disease.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesBLUMLER, J. G. ; BROWN, J. R. ; EWBANK, A. J. ; NOSSITER, T. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1971Staff ViewISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesSong, I.-S. ; Bunnett, N. W. ; Olerud, J. E. ; Harten, B. ; Steinhoff, M. ; Brown, J. R. ; Sung, K. J. ; Armstrong, C. A. ; Ansel, J. C.
Copenhagen : Munksgaard International Publishers
Published 2000Staff ViewISSN: 1600-0625Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: The neurological system plays an important role in modulating some inflammatory skin diseases. Neuro-cutaneous interactions may be mediated by the release of neuropeptides such as substance P (SP) which activate immunocompetent cells in the skin by binding to high affinity neurokinin receptors (NKR). Since epidermal keratinocytes produce a variety of cytokines and are intimately associated with cutaneous sensory fibers, we tested the ability of these cells to participate in the cutaneous neuroimmune system by the secretion of potent cytokines such as interleukin 1 (IL-1) in response to released SP. RT-PCR studies demonstrated that cultured PAM 212 murine keratinocytes expressed mRNA for NK-2R but not NK-1R. Correspondingly, the addition of SP to these cells resulted in a rapid increase in intracellular Ca2+ levels that could be specifically blocked by an NK-2R antagonist. NK-2R was also shown in normal mouse epidermis by immunohistochemistry. SP augmented the expression of PAM 212 keratinocyte IL-1α mRNA in a dose and time dependent manner and this induction was inhibited by an NK-2R antagonist. Secretion of bioactive IL-1α by the PAM 212 keratinocytes was likewise stimulated by SP in a dose dependent manner. These data support the hypothesis that SP released from cutaneous sensory nerves contributes to neuroimmune inflammatory responses in the skin by modulating the expression and release of cytokines from epidermal keratinocytes.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1365-2109Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract. A habitat suitability index (HSI) model for suspended tray culture of the Pacific oyster, Crassostrea gigas Thunberg, was constructed from existing information in the literature on oyster-environment relationships. In the model, biophysical data are used to rate aquaculture potential of coastal areas on a scale from 0.0 to 1·0. where 1·0 represents optimal conditions for growth and survival and 0·0 represents totally unsuitable habitat conditions. The model was tested with environmental, growth (increase in shell height) and secondary production (g· 100 oysters−1 day−1) data collected over a 14-month period for two age-classes of oysters transplanted to 10 locations along the coast of British Columbia. Canada. Regressions of HSI values calculated from entire study environmental data against oyster growth and secondary production were highly significant for both age-classes. Environmental data subsets representing short sampling programmers (1–3 months) resulted in HSI values significantly correlated to oyster growth, provided that some sampling occurred during periods of high food availability. HSI modeling techniques have potential application in site selection and coastal management of aquaculture.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0026-7937Topics: Linguistics and Literary StudiesNotes: REVIEWSURL: -
14Articles: DFG German National LicensesWilliamson, J. ; Scott-Finnigan, T. J. ; Hardman, M. A. ; Brown, J. R.
[s.l.] : Nature Publishing Group
Published 1981Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] As none of the daunorubicin analogues tested (see Table 1. and Fig. 1) reproduce the high in vitro trypanocidal activity of daunorubicin, the loss of activity of this drug in vivo must be overcome. We first tested a DNA-daunorubicin complex6 but it was inactive. As this product acts as a ...Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesHARTLEY, B. S. ; BROWN, J. R. ; KAUFFMAN, DOROTHY L. ; SMILLIE, L. B.
[s.l.] : Nature Publishing Group
Published 1965Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] IT is now generally agreed that the amino-acid sequence of a protein is determined by the nucleotide sequence of its parent gene, so that comparison of the sequences of related proteins can provide clues about their genetic origins. If we compare similar proteins from different species we may hope ...Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] In many instances it was not possible to isolate cell lines due to the overwhelming contamination which naturally occurs in these organs. In order to overcome this difficulty., the regular procedures of cell isolation were adapted to the special needs. The tissues from lung cervix and other ...Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0018-2370Topics: HistoryNotes: Book ReviewsURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: