Search Results - (Author, Cooperation:J. Q. Feng)
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1W. Tang ; Y. Lu ; Q. Y. Tian ; Y. Zhang ; F. J. Guo ; G. Y. Liu ; N. M. Syed ; Y. Lai ; E. A. Lin ; L. Kong ; J. Su ; F. Yin ; A. H. Ding ; A. Zanin-Zhorov ; M. L. Dustin ; J. Tao ; J. Craft ; Z. Yin ; J. Q. Feng ; S. B. Abramson ; X. P. Yu ; C. J. Liu
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-03-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adolescent ; Adult ; Aged ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/metabolism/pharmacology/therapeutic use ; Arthritis, Experimental/*drug therapy/*immunology/pathology/physiopathology ; Cartilage, Articular/metabolism/pathology ; Female ; Humans ; Intercellular Signaling Peptides and ; Proteins/chemistry/genetics/*metabolism/therapeutic use ; Ligands ; Male ; Mice ; Mice, Inbred Strains ; Mice, Knockout ; Mice, Transgenic ; Middle Aged ; Protein Interaction Domains and Motifs ; Receptors, Tumor Necrosis Factor, Type I/genetics/*metabolism ; Receptors, Tumor Necrosis Factor, Type II/genetics/*metabolism ; Recombinant Fusion Proteins/metabolism/pharmacology/therapeutic use ; Recombinant Proteins/therapeutic use ; Signal Transduction ; T-Lymphocytes, Regulatory/immunology/physiology ; Tumor Necrosis Factor-alpha/*metabolism ; Young AdultPublished by: -
2DePaoli, D. W. ; Feng, J. Q. ; Basaran, O. A. ; Scott, T. C.
[S.l.] : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7666Source: AIP Digital ArchiveTopics: PhysicsNotes: A hysteresis phenomenon has been revealed through experiments conducted with large-amplitude forced oscillations of pendant drops in air. Under strong excitation, the frequency response of a drop forced at constant amplitude exhibits jump behavior; a larger peak response amplitude ε↓ appears at a lower frequency ω↓ during a downward (↓) variation of forcing frequency than during an upward (↑) variation, viz. ε↓(approximately-greater-than)ε↑ and ω↓〈ω↑. Similar results are obtained when forcing amplitude is varied at constant frequency. This behavior is characteristic of a system with a soft nonlinearity. These findings indicate that oscillating pendant drops constitute a convenient system for studying nonlinear dynamics. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
3Chen, D. ; Harris, M. A. ; Rossini, G. ; Dunstan, C. R. ; Dallas, S. L. ; Feng, J. Q. ; Mundy, G. R. ; Harris, S. E.
Springer
Published 1997Staff ViewISSN: 1432-0827Keywords: Key words: BMP-2 — BMP-3 — BMP-4 — mRNA expression — Paracrine — Bone cell differentiation.Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsNotes: Abstract. Normal bone formation is a prolonged process that is carefully regulated and involves sequential expression of growth regulatory factors by osteoblasts as they proliferate and ultimately differentiate. Since this orderly sequence of gene expression by osteoblasts suggests a cascade effect, and BMP-2 is capable of initiating and maintaining this effect, we examined the effects of BMP-2 on expression of other BMPs and compared these effects with the expression pattern of bone cell differentiation marker genes in primary cultures of fetal rat calvarial (FRC) osteoblasts. To examine the gene expression profile during bone cell differentiation and bone formation, we also examined the effects of rBMP-2 on bone formation in vivo and in vitro. rBMP-2 stimulated bone formation on the periosteal surface of mice when 500 ng/day rBMP-2 was injected subcutaneously. When rBMP-2 was added to primary cultures of FRC osteoblasts, it accelerated mineralized nodule formation in a time and concentration-dependent manner (10–40 ng/ml). rBMP-2 (40 ng/ml) enhanced BMP-3 and -4 mRNA expression during the mineralization phase of primary cultures of FRC osteoblasts. Enhancement of BMP-3 and -4 mRNA expression by rBMP-2 was associated with increased expression of bone cell differentiation marker genes, alkaline phosphatase (ALP), type I collagen, osteocalcin (OC), osteopontin (OP), and bone sialoprotein (BSP). These results suggest that BMP-2 enhances expression of other BMP genes during bone cell differentiation. BMP-2 may act in a paracrine fashion in concert with other BMPs it induces to stimulate bone cell differentiation and bone formation during remodeling.Type of Medium: Electronic ResourceURL: -
4Tsouris, C. ; DePaoli, D. W. ; Feng, J. Q. ; Basaran, O. A. ; Scott, T. C.
Hoboken, NJ : Wiley-Blackwell
Published 1994Staff ViewISSN: 0001-1541Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyProcess Engineering, Biotechnology, Nutrition TechnologyAdditional Material: 4 Ill.Type of Medium: Electronic ResourceURL: