Search Results - (Author, Cooperation:J. Porter)
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1Buultjens, A. H., Vandelannoote, K., Meehan, C. J., Eddyani, M., de Jong, B. C., Fyfe, J. A. M., Globan, M., Tobias, N. J., Porter, J. L., Tomita, T., Tay, E. L., Seemann, T., Howden, B. P., Johnson, P. D. R., Stinear, T. P.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-04-03Publisher: The American Society for Microbiology (ASM)Print ISSN: 0099-2240Electronic ISSN: 1098-5336Topics: BiologyPublished by: -
2Nicholas J. Porter, Florence F. Wagner, David W. Christianson
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-05-19Publisher: American Chemical Society (ACS)Print ISSN: 0006-2960Electronic ISSN: 1520-4995Topics: BiologyChemistry and PharmacologyPublished by: -
3Thibault Gendron, Kerstin Sander, Klaudia Cybulska, Laure Benhamou, Pak Kwan Brian Sin, Aqsa Khan, Michael Wood, Michael J. Porter, Erik Årstad
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-08-23Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
4C. Y. Ewald ; J. N. Landis ; J. Porter Abate ; C. T. Murphy ; T. K. Blackwell
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-12-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/physiology ; Animals ; Caenorhabditis elegans/growth & development/*metabolism ; Caenorhabditis elegans Proteins/*metabolism ; Collagen/biosynthesis/genetics/*metabolism ; DNA-Binding Proteins/*metabolism ; Extracellular Matrix/metabolism ; Forkhead Transcription Factors ; Insulin/*metabolism ; Insulin-Like Growth Factor I/*metabolism ; Larva/growth & development ; Longevity/*physiology ; *Signal Transduction ; Transcription Factors/*metabolismPublished by: -
5Samuel W. Teitelbaum, Taeho Shin, Johanna W. Wolfson, Yu-Hsiang Cheng, Ilana J. Porter, Maria Kandyla, and Keith A. Nelson
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-09-26Publisher: American Physical Society (APS)Electronic ISSN: 2160-3308Topics: PhysicsPublished by: -
6J. Barretina ; G. Caponigro ; N. Stransky ; K. Venkatesan ; A. A. Margolin ; S. Kim ; C. J. Wilson ; J. Lehar ; G. V. Kryukov ; D. Sonkin ; A. Reddy ; M. Liu ; L. Murray ; M. F. Berger ; J. E. Monahan ; P. Morais ; J. Meltzer ; A. Korejwa ; J. Jane-Valbuena ; F. A. Mapa ; J. Thibault ; E. Bric-Furlong ; P. Raman ; A. Shipway ; I. H. Engels ; J. Cheng ; G. K. Yu ; J. Yu ; P. Aspesi, Jr. ; M. de Silva ; K. Jagtap ; M. D. Jones ; L. Wang ; C. Hatton ; E. Palescandolo ; S. Gupta ; S. Mahan ; C. Sougnez ; R. C. Onofrio ; T. Liefeld ; L. MacConaill ; W. Winckler ; M. Reich ; N. Li ; J. P. Mesirov ; S. B. Gabriel ; G. Getz ; K. Ardlie ; V. Chan ; V. E. Myer ; B. L. Weber ; J. Porter ; M. Warmuth ; P. Finan ; J. L. Harris ; M. Meyerson ; T. R. Golub ; M. P. Morrissey ; W. R. Sellers ; R. Schlegel ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Lineage ; Chromosomes, Human/genetics ; Clinical Trials as Topic/methods ; *Databases, Factual ; Drug Screening Assays, Antitumor/*methods ; *Encyclopedias as Topic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, ras/genetics ; Genome, Human/genetics ; Genomics ; Humans ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors/metabolism ; *Models, Biological ; Neoplasms/*drug therapy/genetics/metabolism/*pathology ; Pharmacogenetics ; Plasma Cells/cytology/drug effects/metabolism ; Precision Medicine/methods ; Receptor, IGF Type 1/antagonists & inhibitors/metabolism ; Receptors, Aryl Hydrocarbon/genetics/metabolism ; Sequence Analysis, DNA ; Topoisomerase Inhibitors/pharmacologyPublished by: -
7Nicholas J. Porter, Jeremy D. Osko, Daniela Diedrich, Thomas Kurz, Jacob M. Hooker, Finn K. Hansen, David W. Christianson
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-08-18Publisher: American Chemical Society (ACS)Topics: Chemistry and PharmacologyPublished by: -
8CD271+ Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH MedulloblastomaLisa Liang, Ludivine Coudiere–Morrison, Nazanin Tatari, Margaret Stromecki, Agnes Fresnoza, Christopher J. Porter, Marc R. Del Bigio, Cynthia Hawkins, Jennifer A. Chan, Timothy C. Ryken, Michael D. Taylor, Viȷay Ramaswamy, Tamra E. Werbowetski–Ogilvie
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-08-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 0008-5472Electronic ISSN: 1538-7445Topics: MedicinePublished by: -
9Staff View
ISSN: 0031-9422Keywords: Pinaceae ; Pseudotsuga menziesii ; cell suspension cultures ; dihydroquercetin ; enzymatic reduction ; leucocyanidin ; procyanidin biosynthesis.Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0031-9422Keywords: Hepaticae ; Riccia crystallina ; Ricciocarpus natans ; chemotaxonomy. ; liverworts ; simple flavone glycosidesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
Type of Medium: OnlinePublication Date: 2024Keywords: Bildungspolitik ; Sprache ; Bilingualer Unterricht ; Indigenes Volk ; LateinamerikaIn: International review of education, Bd. 70 (2024) H. 1, S. 11-28, 1573-0638Language: English -
12Habibullah, M., Porter, J. A., Kluger, N., Ranki, A., Krohn, K. J. E., Brandi, M. L., Brown, E. M., Weetman, A. P., Kemp, E. H.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-11-20Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
13Hanson, D. L. ; Porter, J. L. ; Williams, R. R.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Experiments are described in which a high-purity, high-power (0.15 TW, 1 MeV) proton beam is generated from an ion source consisting of H2 gas frozen onto a liquid-helium-cooled copper anode at 4.2 K in a series-field-coil extraction diode on the 0.7 TW HydraMITE-II accelerator. Peak anode proton current densities of 2 kA/cm2 were measured. This current density is a factor of 100 higher than those obtained in previous liquid-helium-cooled cryogenic diode experiments on small accelerators and is in the range required for high-power ion beam applications. Thomson parabola, Faraday cup, and carbon activation measurements indicate an ion beam proton fraction close to 100% for the cryogenic source, compared to 50–70% for the standard hydrocarbon anode tested. The cryogenic proton source is believed to consist of no more than a few monolayers of molecular hydrogen. The hydrogen-coated cryogenic anode shows a faster initial anode turn-on than other materials. However, source-limited emission from the thin hydrogen layer results in a somewhat longer current risetime, reduced ion diode efficiency, lower proton current enhancement over the Child–Langmuir limit, and a proton spectrum of lower average energy than for the hydrocarbon anode. Techniques to overcome these limitations are discussed. Cryogenic ion sources consisting of frozen N2, CH4, and Ne have also been studied. In each case, high intensity beams consisting predominantly of components of the refrigerated gas were produced.Type of Medium: Electronic ResourceURL: -
14Hanson, D. L. ; Williams, R. R. ; Porter, J. L. ; Spielman, R. B. ; Matzen, M. K.
[S.l.] : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Accurate modeling of load behavior in Z-pinch plasma radiation sources driven by high-current generators requires the measurement of fast-rise-time multimegampere currents close to the load. Conventional current diagnostics mounted in inductive cavities (such as B-dot loops and Rogowski coils) fail at small radius because of electrical breakdown produced by high dI/dt. In this paper, we describe the use of large-signal, nanosecond-time-resolution lithium niobate piezoelectric stress gauges to directly measure the magnetic pressure B2/2μ0=μ0I2/8π2r2 generated at radius r by a current I flowing in a radial transmission line. Current measurements have been performed at radius r=2.54×10−2 m on Sandia National Laboratories' Proto-II (10 TW) and SATURN (30 TW) gas puff Z-pinch experiments with maximum currents of 10.1 MA and dI/dt to 2.1×1014 A/s. Comparisons with Faraday rotation and B-dot current diagnostic measurements at large radius are presented. Bremsstrahlung noise problems unique to the SATURN gas puff source are discussed. For a Y-cut lithium niobate stress gauge on a pure tungsten electrode, current densities up to I/2πr=78 MA/m can be measured before the electrode yield strength and the piezoelectric operating stress limit are exceeded. Above the Hugoniot elastic limit of the electrode material, the dynamic range and accuracy of the diagnostic are greatly reduced, but it appears that the technique can be extended to higher current densities using an X-cut quartz piezoelectric element and a tungsten-sapphire electrode impedance stack.Type of Medium: Electronic ResourceURL: -
15Hanson, D. L. ; Vesey, R. A. ; Cuneo, M. E. ; Porter, J. L. ; Chandler, G. A. ; Ruggles, L. E. ; Simpson, W. W. ; Torres, J. ; McGurn, J. ; Hebron, D. ; Dropinski, S. C.
[S.l.] : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The Z-pinch-driven hohlraum (ZPDH) [J. H. Hammer et al., Phys. Plasmas 6, 2129 (1999)] is a promising approach to high yield inertial confinement fusion currently being characterized in experiments on the Sandia Z accelerator [M. E. Cuneo et al., Phys. Plasmas 8, 2257 (2001)]. Simulations show that capsule radiation symmetry, a critical issue in ZPDH design, is governed primarily by hohlraum geometry, dual-pinch power balance, and pinch timing. In initial symmetry studies on Z without the benefit of a laser backlighter, highly-asymmetric pole-hot and equator-hot single Z-pinch hohlraum geometries were diagnosed using solid low density foam burnthrough spheres. These experiments demonstrated effective geometric control and prediction of polar flux symmetry at the level where details of the Z-pinch implosion and other higher order effects are not critical. Radiation flux symmetry achieved in Z double-pinch hohlraum configurations exceeds the measurement sensitivity of this self-backlit foam ball symmetry diagnostic. To diagnose radiation symmetry at the 2%–5% level attainable with present ZPDH designs, high-energy x rays produced by the recently-completed Z-Beamlet laser backlighter are being used for point-projection imaging of thin-wall implosion and symmetry capsules. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
16Baker, K. L. ; Porter, J. L. ; Ruggles, L. E. ; Chandler, G. A. ; Deeney, Chris ; Vargas, M. ; Moats, Ann ; Struve, Ken ; Torres, J. ; McGurn, J. S. ; Simpson, W. W. ; Fehl, D. L. ; Jobe, D. O.
[S.l.] : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: In this article we investigate the partial closure of diagnostic holes in Z-pinch driven hohlraums. These hohlraums differ from current laser-driven hohlraums in a number of ways such as their larger size, greater x-ray drive energy, and lower temperature. Although the diameter of the diagnostic holes on these Z-pinch driven hohlraums can be much greater than their laser-driven counterparts, 4 mm in diameter or larger, radiation impinges on the wall material surrounding the hole for the duration of the Z pinch, nearly 100 ns. This incident radiation causes plasma to ablate from the hohlraum walls surrounding the diagnostic hole and partially obscure this diagnostic hole. This partial obscuration reduces the effective area over which diagnostics view the hohlraum's radiation. This reduction in area can lead to an underestimation of the wall temperature when nonimaging diagnostics such as x-ray diodes and bolometers are used to determine power and later to infer a wall temperature. In this article we describe the techniques used to characterize the hole-closure in these hohlraums and present the experimental measurements of this process. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
17Spielman, R. B. ; Deeney, C. ; Chandler, G. A. ; Douglas, M. R. ; Fehl, D. L. ; Matzen, M. K. ; McDaniel, D. H. ; Nash, T. J. ; Porter, J. L. ; Sanford, T. W. L. ; Seamen, J. F. ; Stygar, W. A. ; Struve, K. W. ; Breeze, S. P. ; McGurn, J. S. ; Torres, J. A. ; Zagar, D. M. ; Gilliland, T. L. ; Jobe, D. O. ; McKenney, J. L. ; Mock, R. C. ; Vargas, M. ; Wagoner, T.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Here Z, a 60 TW/5 MJ electrical accelerator located at Sandia National Laboratories, has been used to implode tungsten wire-array Z pinches. These arrays consisted of large numbers of tungsten wires (120–300) with wire diameters of 7.5 to 15 μm placed in a symmetric cylindrical array. The experiments used array diameters ranging from 1.75 to 4 cm and lengths from 1 to 2 cm. A 2 cm long, 4 cm diam tungsten array consisting of 240, 7.5 μm diam wires (4.1 mg mass) achieved an x-ray power of ∼200 TW and an x-ray energy of nearly 2 MJ. Spectral data suggest an optically thick, Planckian-like radiator below 1000 eV. One surprising experimental result was the observation that the total radiated x-ray energies and x-ray powers were nearly independent of pinch length. These data are compared with two-dimensional radiation magnetohydrodynamic code calculations. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
18Suter, L. J. ; Kauffman, R. L. ; Darrow, C. B. ; Hauer, A. A. ; Kornblum, H. ; Landen, O. L. ; Orzechowski, T. J. ; Phillion, D. W. ; Porter, J. L. ; Powers, L. V. ; Richard, A. ; Rosen, M. D. ; Thiessen, A. R. ; Wallace, R.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Nearly 10 years of Nova [E. M. Campbell, Laser Part. Beams 9, 209 (1991)] experiments and analysis have lead to a relatively detailed quantitative and qualitative understanding of radiation drive in laser-heated hohlraums. Our most successful quantitative modeling tool is two-dimensional (2-D) LASNEX numerical simulations [G. B. Zimmerman and W. L. Kruer, Comments Plasma Phys. Controlled Fusion 2, 51 (1975)]. Analysis of the simulations provides us with insight into the physics of hohlraum drive. In particular we find hohlraum radiation conversion efficiency becomes quite high with longer pulses as the accumulated, high-Z blow-off plasma begins to radiate. Extensive Nova experiments corroborate our quantitative and qualitative understanding. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Olson, R. E. ; Porter, J. L. ; Chandler, G. A. ; Fehl, D. L. ; Jobe, D. O. ; Leeper, R. J. ; Matzen, M. K. ; McGurn, J. S. ; Noack, D. D. ; Ruggles, L. E. ; Sawyer, P. ; Torres, J. A. ; Vargas, M. ; Zagar, D. M.
[S.l.] : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The Saturn pulsed power accelerator [R. B. Spielman et al., in Proceedings of the 2nd International Conference on Dense Z-pinches, Laguna Beach, CA, 1989, edited by N. R. Pereira, J. Davis, and N. Rostoker (American Institute of Physics, New York, 1989), p. 3] at Sandia National Laboratories (SNL) and the Nova laser [J. T. Hunt and D. R. Speck, Opt. Eng. 28, 461 (1989)] at Lawrence Livermore National Laboratory (LLNL) have been used to explore techniques for studying the behavior of ablator material in x-ray radiation environments comparable in magnitude, spectrum, and duration to those that would be experienced in National Ignition Facility (NIF) hohlraums [J. D. Lindl, Phys. Plasmas 2, 3933 (1995)]. The large x-ray outputs available from the Saturn pulsed-power-driven z pinch have enabled us to drive hohlraums of full NIF ignition scale size at radiation temperatures and time scales comparable to those required for the low-power foot pulse of an ignition capsule. The high-intensity drives available in the Nova laser have allowed us to study capsule ablator physics in smaller-scale hohlraums at radiation temperatures and time scales relevant to the peak power pulse for an ignition capsule. Taken together, these experiments have pointed the way to possible techniques for testing radiation-hydrodynamics code predictions of radiation flow, opacity, equation of state, and ablator shock velocity over the range of radiation environments that will be encountered in a NIF hohlraum. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
20Ruggles, L. E. ; Porter, J. L. ; Simpson, W. W. ; Vargas, M. F.
[S.l.] : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: Microchannel plate intensified (MPI) x-ray detectors are commonly used for imaging and spectral measurements in the 100–1500 eV photon energy range. Using a laser-produced plasma x-ray source, we measured the integrated detector response versus incident x-ray intensity and the relative efficiency versus photon energy of a MPI x-ray detector. Two identical 2000 lines/mm transmission grating spectrometers simultaneously record broadband plasma source emission from a tantalum target. The relative efficiency was determined by comparing the spectrum recorded with an absolutely calibrated x-ray CCD reference detector on one spectrometer to the spectrum recorded with a MPI x-ray detector on the other spectrometer. The integrated detector response versus incident x-ray intensity was measured by simultaneously illuminating the CCD reference detector and the MPI detector with step-wedge-filtered magnesium plasma emission. The aluminum step wedge x-ray filters pass the 1s–2p emission lines of H-like Mg at 1470 eV and the 1s2–1s2p emission lines of He-like Mg at 1350 eV, and provide a four order of magnitude range in incident intensity on the detectors.© 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: