Search Results - (Author, Cooperation:J. Paterson)

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  1. 1
    E. Ruark ; K. Snape ; P. Humburg ; C. Loveday ; I. Bajrami ; R. Brough ; D. N. Rodrigues ; A. Renwick ; S. Seal ; E. Ramsay ; V. Duarte Sdel ; M. A. Rivas ; M. Warren-Perry ; A. Zachariou ; A. Campion-Flora ; S. Hanks ; A. Murray ; N. Ansari Pour ; J. Douglas ; L. Gregory ; A. Rimmer ; N. M. Walker ; T. P. Yang ; J. W. Adlard ; J. Barwell ; J. Berg ; A. F. Brady ; C. Brewer ; G. Brice ; C. Chapman ; J. Cook ; R. Davidson ; A. Donaldson ; F. Douglas ; D. Eccles ; D. G. Evans ; L. Greenhalgh ; A. Henderson ; L. Izatt ; A. Kumar ; F. Lalloo ; Z. Miedzybrodzka ; P. J. Morrison ; J. Paterson ; M. Porteous ; M. T. Rogers ; S. Shanley ; L. Walker ; M. Gore ; R. Houlston ; M. A. Brown ; M. J. Caufield ; P. Deloukas ; M. I. McCarthy ; J. A. Todd ; C. Turnbull ; J. S. Reis-Filho ; A. Ashworth ; A. C. Antoniou ; C. J. Lord ; P. Donnelly ; N. Rahman
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-12-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Breast Neoplasms/*genetics ; Cluster Analysis ; Exons ; Female ; Genetic Predisposition to Disease/*genetics ; Humans ; Isoenzymes/genetics ; Lymphocytes/metabolism ; *Mosaicism ; *Mutation ; Ovarian Neoplasms/*genetics ; Phosphoprotein Phosphatases/*genetics ; Sequence Analysis, DNA ; Tumor Suppressor Protein p53/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-10-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Agriculture ; Animals ; *Climate Change ; *Conservation of Natural Resources ; *Decision Support Techniques ; *Ecosystem ; *Models, Economic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2013-07-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Agriculture ; Animals ; Biodiversity ; *Climate Change ; *Conservation of Natural Resources ; Decision Making ; *Decision Support Techniques ; *Ecosystem ; Great Britain ; Marketing ; *Models, Economic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-12-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Geochemistry, Geophysics, Physics, Planetary Science
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Sing L, Metzger M, Paterson J, et al.
    Oxford University Press
    Published 2018
    Staff View
    Publication Date:
    2018-03-09
    Publisher:
    Oxford University Press
    Print ISSN:
    0015-752X
    Electronic ISSN:
    1464-3626
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by:
    http://global.oup.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    McMullan, D. ; Paterson, J.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1989
    Staff View
    ISSN:
    1089-7658
    Source:
    AIP Digital Archive
    Topics:
    Mathematics
    Physics
    Notes:
    The aim of any constraint quantization procedure is to be able to recover the physical content of a system after quantizing on the extended state space (which will include both physical and unphysical configurations). Within the Dirac approach to such problems there is no guarantee that the resulting quantum theory will be equivalent to the quantized physical theory and one has to be content with a case by case analysis of its applicability. In this paper it is shown that for finite-dimensional systems with first class constraints linear in momenta, invariance under constraint rescaling and point transformations is sufficient to ensure a consistent quantization. As discussed in the preceding paper [J. Math. Phys. 30, XXX (1989)], in order to become a manifest symmetry, constraint rescaling requires ghost variables. It is now shown how the associated BRST charge is constructed and how it is used to describe the physical states and observables in the constrained system. The extension of this construction to more general constrained systems is also discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.528415

    Articles: DFG German National Licenses
  7. 7
    McMullan, D. ; Paterson, J.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1989
    Staff View
    ISSN:
    1089-7658
    Source:
    AIP Digital Archive
    Topics:
    Mathematics
    Physics
    Notes:
    A dynamical consequence of local gauge invariance is the existence of first class constraints that are linear in momenta. By studying finite-dimensional systems with this constraint structure one finds that, in order to quantize such theories, it is not enough to find a consistent factor ordering, rather, one must also maintain covariance under rescaling of the constraints, point transformations, and weak changes to the observables. Within the standard Dirac constraint formalism, covariance under these symmetries obstructs a full Hilbert space description. It is shown how this difficulty may be overcome by the use of ghost variables. In the present paper, I, an analysis of the Becchi–Rouet–Stora–Tyutin (BRST) structure of such systems is presented. The constraint rescaling is shown to be implemented by a canonical transformation on the super phase space that can be evaluated to a unitary transformation on a suitably defined state space. In the following paper, II [J. Math. Phys. 30, xxx (1989)] these techniques are used to solve the constraint factor ordering problem.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.528414

    Articles: DFG German National Licenses
  8. 8
    Castleden, L. I. M. ; Hamilton-Paterson, J. L. ; Rosser, E. ap I.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1951
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-0528.1951.tb04908.x

    Articles: DFG German National Licenses
  9. 9
    Pincosy, P. A. ; Ehlers, K. W. ; Lietzke, A. F. ; Owren, H. M. ; Paterson, J. A. ; Pyle, R. V. ; Vella, M. C.

    [S.l.] : American Institute of Physics (AIP)
    Published 1986
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    Users of fusion devices have identified heating requirements for positive ion based neutral beams to include energies of 80 or 120 kV with pulse length up to 30 s. Additional requirements are low beam divergence (0.3°×1.0°; 1/e half angles), low impurity (less than 1%), high species (over 80% atomic), and cathode lifetime exceeding 5 h of beam operation. Accelerator design remains as an engineering problem, whereas most of the performance goals have required development of the plasma generator. Problems of concern which relate to the performance goals are the heat dissipation, magnetic field configuration, and cathode placement. The plasma generator was tested on TS IIA (the plasma generator testing facility) which does not have beam extraction capability but is used to evaluate efficiency, operating conditions, arc notching characteristics, species, plasma uniformity, and cathode conditioning. The source, consisting of the plasma generator mounted on the long pulse accelerator was mounted on NBETF (Neutral Beam Engineering Test Facility) for beam testing. During beam operation the back-streaming electrons add power to the source and affect the arc operation. Source durability and stability were studied at 80 kV and 40 A of accelerator current (deuterium). The arc efficiency was higher than the value used for the design. Power loading from back-streaming electrons was much less than the design level. With feedback control, plasma density and accel current were constant to ±2% during 30-s shots. The beam atomic fraction of 84%–88% (deuterium) was slightly higher than measured on TS IIA. Cathode durability was tested by operating over 500, 30-s full shots at 80 kV and 40 A of deuterium. Arc conditioning was found to be an important phase to avoid filament damage.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1139081

    Articles: DFG German National Licenses
  10. 10
    Weber, P. D. ; Owren, H. M. ; Paterson, J. A. ; Pincosy, P. A. ; Pyle, R. V. ; Wells, R. P. ; Vella, M. C.

    [S.l.] : American Institute of Physics (AIP)
    Published 1986
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    The 10×40-cm long pulse neutral beam source developed at Lawrence Berkeley Laboratory has been selected as the prototype for the design of the U. S. common long pulse source to be used on tokamak fusion test reactor (TFTR), Doublet-III, and mirror fusion test facility (MFTF-B). The long pulse source consists of a magnetic line cusp bucket with an actively cooled backplate electron dump and a four-grid accelerator using slot apertures and water-cooled molybdenum rails. Deuterium testing of the long pulse source at 120 kV and 53 A and with a 2-s pulse length has been completed on the neutral beam engineering test facility, including an 8-h 100-shot test to demonstrate the durability and reliability of the source. Maximum 2-s beam parameters obtained (not simultaneously) are 125 kV, 58 A (deuterium), and 7.1 MW. Beam pulse length has been extended to 5 s at 120 kV. Atomic species fractions in excess of 80% have been obtained, with a beam divergence (full energy, 1/e half-angle) of approximately 0.8×0.4°. Calorimetric measurements on the accelerator grids and backplate electron dump indicate heat loads consistent with predictions and within the design limits of the source. This testing has verified the design of the source and its ability to exceed the basic performance requirements.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.1139082

    Articles: DFG German National Licenses
  11. 11
    Paterson, J. ; Natansohn, A. ; Rochon, P. ; Callender, C. L. ; Robitaille, L.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Surface relief diffraction gratings inscribed on azobenzene-containing polymers are designed to act as light couplers into slab waveguides. The gratings are inscribed both directly in poly{4-[2-(methacryloyloxy)ethyl]azobenzene} (pMEA) waveguide material, and in an azopolymer cladding layer applied to polyimide, silicon nitride, and silicon oxynitride films. Input and output coupling of both 633 and 830 nm light is observed in the waveguides. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.117292

    Articles: DFG German National Licenses
  12. 12
    NORMANDALE, J. P. ; SCHMULIAN, C. ; PATERSON, J. L. ; BURRIN, J. ; MORGAN, M. ; HALL, G. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1985
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The effect of the administration of diamorphine 10 mg epidurally on the metabolic response to cholecystectomy was investigated and compared with a control group of patients given intravenous papaveretum. There were no significant differences in blood glucose, lactate and pyruvate, and plasma nonesterified fatty acid values between the epidural diamorphine group and the control group. Plasma cortisol concentrations were significantly lower in the epidural diamorphine group postoperatively and this was associated with a marked improvement in pain relief. We conclude that epidural opiates do not directly influence the metabolic response to surgery, but decrease the cortisol response postoperatively secondary to improved analgesia.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2044.1985.tb10998.x

    Articles: DFG German National Licenses
  13. 13
    BENT, J. M. ; PATERSON, J. L. ; MASHITER, K. ; HALL, G. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1984
    Staff View
    ISSN:
    1365-2044
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The effect of the administration of fentanyl 50 μg/kg body weight on the established metabolic response to pelvic surgery was investigated. In comparison with a control group of patients in whom anaesthesia was supplemented with halothane, fentanyl was associated with a significant decrease in only blood lactate concentrations and heart rate. There were no significant differences in blood glucose, plasma non-esterified fatty acids, and plasma cortisol values between the two anaesthetic techniques. It is concluded that the administration of high-dose fentanyl has little effect on the established metabolic response to surgery, compared with the marked changes observed when the same dose is given before the onset of surgical stimulation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2044.1984.tb09447.x

    Articles: DFG German National Licenses
  14. 14
    Lulich, K. M. ; Papadimitriou, J. M. ; Paterson, J. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1979
    Staff View
    ISSN:
    1440-1681
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    1. The use of the isolated lung strip and single open tracheal ring for studying Schultz Dale anaphylactic contractions in both the peripheral and central airways is described.2. This method is particularly relevant to studies of anaphylaxis because many preparations may be obtained from a single sensitized animal.3. Isolated preparations from control guinea-pigs did not respond to ovalbumin, whereas the lung strip and trachea taken from guinea-pigs sensitized to ovalbumin, contracted markedly to that antigen.4. The peripheral and central airways from sensitized animals responded in the same way to antigen challenge.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1440-1681.1979.tb00046.x

    Articles: DFG German National Licenses
  15. 15
    PATERSON, J. S. ; DORMAN, R. G. ; DARLOW, H. M. ; COOK, R.

    [s.l.] : Nature Publishing Group
    Published 1970
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] SIB,-We feel it our duty to draw to your attention and to contradict what we consider to be a dangerous statement in the leader on the Pirbright outbreak of foot-and-mouth disease (Nature, 228, 403; 1970) in which the writer states unequivocally, "but it is well known that no biological filter can ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/2281237b0

    Articles: DFG German National Licenses
  16. 16
    PATERSON, H. E. ; PATERSON, J. S. ; VAN EEDEN, G. J.

    [s.l.] : Nature Publishing Group
    Published 1964
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Although some records have been published810 of breeding by members of the A. gambiae complex in saline waters at inland localities, the only one investigated10 seemed, to be due to either species A or species B, though the methods used to decide this are open to some criticism. The purpose of this ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/201524a0

    Articles: DFG German National Licenses
  17. 17
    McMullan, D. ; Paterson, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0370-2693(88)90485-6

    Articles: DFG German National Licenses
  18. 18
    BERRIE, ALEX. M. M. ; PATERSON, J. ; WEST, H. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1974
    Staff View
    ISSN:
    1399-3054
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Lettuce seed (Lactuca sativa L. cv. Grand Rapids) prevented from attaining maximum water content are still able to respond to irradiation if the seed moisture content is above 6%. When the limitation to water uptake is by immersion in a solution of either polyethylene glycol 400 (PEG 400), mannitol, or sucrose, the responsiveness of the seed is lessened.With PEG 400 the molarity which reduces germination by about 50% is 0.03 while mannitol and sucrose must be present at 0.07M and 0.05 M respectively to bring about the same reduction.While red light overcomes any additional effect 0.1 M mannitol and 0.025 M PEG 400 have on lettuce seed at 30°C (at which temperature the sample was positively photoblastic), irradiation did not overcome the effect of 0.1 M sucrose. Gibberellic acid did not have any effect on any of the treated seed.The solutes used cannot be considered as inert. Some chemical activity is associated with them and it is unwise to consider using these molecules to establish a particular level of water potential in the liquid bathing the seed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1399-3054.1974.tb03110.x

    Articles: DFG German National Licenses
  19. 19
    McLachlin, John ; Paterson, J. C.
    Springer
    Published 1958
    Staff View
    ISSN:
    1432-1440
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Zusammenfassung Unsere Beobachtungen über verschiedene Seiten des Problems der Venenthrombose wurden zusammenfassend dargestellt. Der häufigste Ursprungsort der venösen Thromben wurde in den Beckenvenen und weniger in den Wadenvenen gefunden. Die venöse Stase der Venen des Beckens und der unteren Extremitäten ist für die Entstehung der Venenthrombose wichtiger als primäre Veränderungen der Venenwände oder Anomalien der Blutgerinnung. Die auffallende Tendenz der venösen Thromben, besonders der beginnenden, ihren Anfang in der Tiefe der Klappentaschen zu nehmen, spricht weiterhin dafür, daß in der Ätiologie der Venenthrombosis die venöse Stase des Blutes die Hauptrolle spielt. Die chirurgische Unterbindung der oberflächlichen Vena femoralis bei Lungenembolien zu prophylaktischen bzw. therapeutischen Zwecken hat nach unseren Untersuchungen keine ausreichende Grundlage.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01488741

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0168-9002
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0168-9002(94)91878-3

    Articles: DFG German National Licenses