Search Results - (Author, Cooperation:J. Mundy)
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1Kohnken, R., Wen, J., Mundy-Bosse, B., McConnell, K., Keiter, A., Grinshpun, L., Hartlage, A., Yano, M., McNeil, B., Chakravarti, N., William, B., Bradner, J. E., Caligiuri, M. A., Porcu, P., Mishra, A.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-02-16Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid NeoplasiaPublished by: -
2Richard C. Remsing, Timothy T. Duignan, Marcel D. Baer, Gregory K. Schenter, Christopher J. Mundy and John D. Weeks
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-02-10Publisher: American Chemical Society (ACS)Electronic ISSN: 1520-5207Topics: Chemistry and PharmacologyPhysicsPublished by: -
3L. Orlando ; A. Ginolhac ; G. Zhang ; D. Froese ; A. Albrechtsen ; M. Stiller ; M. Schubert ; E. Cappellini ; B. Petersen ; I. Moltke ; P. L. Johnson ; M. Fumagalli ; J. T. Vilstrup ; M. Raghavan ; T. Korneliussen ; A. S. Malaspinas ; J. Vogt ; D. Szklarczyk ; C. D. Kelstrup ; J. Vinther ; A. Dolocan ; J. Stenderup ; A. M. Velazquez ; J. Cahill ; M. Rasmussen ; X. Wang ; J. Min ; G. D. Zazula ; A. Seguin-Orlando ; C. Mortensen ; K. Magnussen ; J. F. Thompson ; J. Weinstock ; K. Gregersen ; K. H. Roed ; V. Eisenmann ; C. J. Rubin ; D. C. Miller ; D. F. Antczak ; M. F. Bertelsen ; S. Brunak ; K. A. Al-Rasheid ; O. Ryder ; L. Andersson ; J. Mundy ; A. Krogh ; M. T. Gilbert ; K. Kjaer ; T. Sicheritz-Ponten ; L. J. Jensen ; J. V. Olsen ; M. Hofreiter ; R. Nielsen ; B. Shapiro ; J. Wang ; E. Willerslev
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-06-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Conservation of Natural Resources ; DNA/analysis/genetics ; Endangered Species ; Equidae/classification/genetics ; *Evolution, Molecular ; Fossils ; Genetic Variation/genetics ; Genome/*genetics ; History, Ancient ; Horses/classification/*genetics ; *Phylogeny ; Proteins/analysis/chemistry/genetics ; Yukon TerritoryPublished by: -
4HAWKINS, R. E. ; ROBERTS, K. ; WILTSHAW, E. ; MUNDY, J. ; FRYATT, I. J. ; McCREADY, V.
Oxford, UK : Blackwell Publishing Ltd
Published 1989Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Various prognostic factors were studied in 29 patients with stage III or IV ovarian cancer who responded to initial chemotherapy after initial diagnostic surgery. The half-life of CA 125 in serum during initial chemotherapy was the most important prognostic indicator for survival (P〈0·001) and the chance of achieving complete remission (P= 0·012). A CA 125 half-life of 〈20 days, 20–40 days and 〉40 days appears to identify patients with a good, intermediate or poor prognosis, the two year actuarial survival being 76%, 48% and 0% respectively. The chance of achieving a complete remission was 15% and 67% respectively for patients with a serum CA 125 half-life of 〉20 or 〈20 days.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: An exercise in quality assurance during neuroanaesthetic procedures identified uncontrolled re-use of armoured latex rubber tracheal tubes as a risk factor associated with equipment failure. We recommend that such lubes should be used once only. Alternatively, tubes made from more stable materials, such as polyvinyl chloride and silicone rubber, are available for clinical evaluation.Type of Medium: Electronic ResourceURL: -
6Logemann, J. ; Jach, G. ; Tommerup, H. ; Mundy, J. ; Schell, J.
[s.l.] : Nature Publishing Company
Published 1992Staff ViewISSN: 1546-1696Source: Nature Archives 1869 - 2009Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: [Auszug] We have obtained transgenic tobacco plants that express a barley ribosome inactivating protein (RIP) under control of the wound-inducible promoter of the potato wun1 gene. R0 transformants selected on kanamycin were tested for growth in soil inoculated with the soil-borne phyto-pathogen Rhizoctonia ...Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0007-490XTopics: HistoryRomance StudiesURL: -
8Staff View
ISSN: 0014-5793Keywords: (Barley) ; Abscisic acid ; Aleurone ; Gibberellic acid ; translatable mRNA ; β-GlucanaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0014-5793Keywords: Bifunctional α-amylase/subtilisin inhibitor ; Enzymne inhibitor homology ; N-terminal amino acid sequence ; Soybean inhibitor (Kunitz) ; Wheat seedSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0732-3123Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MathematicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0168-9452Keywords: barley ; endosperm development ; gene expression ; protease/enzyme inhibitorSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0007-490XTopics: HistoryRomance StudiesURL: -
14Staff View
ISSN: 0942-0940Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Two hydrocephalic Hy 3 mice and an infant with hydrocephalus and the Arnold-Chiari malformation were examined with the scanning electron microscope. Both mice had advanced hydrocephalus but had normal appearances in the basal regions of the ventricles. However, as the ventricular walls were ascended first the cilia gradually disappeared, then the microvilli, and finally on the roof of the ventricle the ependymal cells disappeared leaving the subependymal layers exposed. The infant had mild hydrocephalus and normal ependymal appearances. The most likely explanation of these findings is that they are a consequence of raised intracranial pressure, and are not the cause of hydrocephalus.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1432-2048Keywords: Abscisic acid and mRNA induction ; Aleurone ; Amylase/Protease inhibitor ; Gibberellin and mRNA induction ; Hordeum (aleurone protein)Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract We have cloned and sequenced a 650-nucleotide cDNA from barley (Hordeum vulgare L.) aleurone layers encoding a protein that is closely related to a known α-amylase inhibitor from Indian finger millet (Eleusine coracana Gaertn.), and that has homologies to certain plant trypsin inhibitors. mRNA for this probable amylase/protease inhibitor (PAPI) is expressed primarily in aleurone tissue during late development of the grain, as compared to that for the amylase/subtilisin inhibitor, which is expressed in endosperm during the peak of storage-protein synthesis. PAPI mRNA is present at high levels in aleurone tissue of desiccated, mature grain, and in incubated aleurone layers prepared from rehydrated mature seeds. Its expression in those layers is not affected by either abscisic acid or gibberellic acid, hormones that, respectively, increase and decrease the abundance of mRNA for the amylase/subtilisin inhibitor. PAPI mRNA is almost as abundant in gibberellic acid-treated aleurone layers as that for α-amylase, and PAPI protein is synthesized in that tissue at levels that are comparable to α-amylase. PAPI protein is secreted from aleurone layers into the incubation medium.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Refractive index and density measurements are given for the ternary systemsX M2O :Y Al2O3: (1 -X -Y)GeO2 where M = sodium and rubidium for Na/(Na + Rb) = 0, 0.3, 0.5, 0.7 and 1.0; (1 -X -Y) = 0.7, 0.8 and 0.9 andY/X = 0, 0.3 and 1.0. The values of the molar refractivity,R, are related to the structure of the glass. At low alkali concentrations, the decrease inR with increasingX is related to the closer packing of the network. At high alkali concentrations the changes inR appear to be controlled by the introduction of non-bridging oxygens into the network. Alumina additions to the germania network strongly increaseR and this appears to be related to change in the network packing brought about by the conversion of Ge4+ from octahedral to tetrahedral coordination.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1573-5028Keywords: α-amylase-promoter ; abscisic acid-induced gene expression ; gibberellin-induced gene expression ; intracellular pH ; Rab promoter ; transient expressionSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Intracellular pH (pHi) of barley aleurone cells is known to be affected by hormones and plant growth conditions. The possible mechanisms by which these pHi shifts influence the actions of abscisic acid (ABA) or gibberellin (GA) is being investigated. Here we report an attempt to study the effect of pHi on hormone-induced gene expression. We used weak acids and weak bases to artificially mimic the pHi changes brought about by ABA and GA and found that chloramphenicol acetyltransferase (CAT) expression controlled by the Rab promoter was affected while the α-amylase promoter seemed insensitive. CAT fused to the 35S promoter was used as a control which is not inducible by ABA or GA3. The expression of this construct was not significantly affected by artificial pHi changes.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1432-5225Source: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Summary The development of rheological models to predict creep has led to the derivation of quite complex equations that can predict creep reasonably accurately. However, these models are conceptual and are not based on a fundamental understanding of the actual deformation processes occurring within the material. The concept of modelling creep using a chemical kinetic approach is one that attempts to understand creep in wood at a molecular level and, from this, to develop models that more accurately predict creep deflections. This paper presents two models developed from chemical kinetic theory, that describe the time-dependant deformation of wood. The validity of applying these models to experimental data has been assessed by stress relaxation tests on thin samples of Sequoia sempervirens. Two stages of experimentation were carried out. In stage 1, both models were applied to the results of stress relaxation tests on 6 samples. Similar values of activation energy and activation volume were calculated by both models and a single energy barrier was found to dominate the deformation process. In stage 2, the effect of varying the initial applied stress on activation energy and activation volume was assessed by carrying out stress relaxation tests at stress levels of 25%, 30% and 35% of the short-term strength. Values of activation energy and activation were found to increase as the applied stress level decreased. Both models describe the time-dependent behaviour of wood well, however their ability to predict long-term creep deflections may be limited. Future work will develop these models further in order to improve long-term creep prediction and then apply them to the results of both creep and stress relaxation tests at a variety of stress levels and moisture contents in order to test their validity.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1432-5225Source: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Summary The applicability of models for describing the short-term properties of chipboard were investigated using the results from experiments conducted on samples of a laboratory-made chipboard (comprised of Scots pine chips and urea formaldehyde resin), and sections of urea formaldehyde and Scots pine strips. The “rule of mixtures” equations, modified for short fibre composites, were employed to predict the strength and stiffness of chipboard. They were found to provide a good estimate of both the chipboard strength and modulus of elasticity, with the assumptions being made that the chips were aligned parallel to the direction of applied stress and that the chips could be treated as having cylindrical geometry. The results of this investigation revealed that chipboard is a highly unusual material. Compared to conventional fibre-reinforced composites, chipboard has a very high volume fraction of fibres, and the similar moduli of elasticity of the fibres and matrix can result in the concentration of stress in the matrix rather than in the fibres. However, these factors did not prevent the assessment and development of appropriate short fibre composite models to predict the strength and stiffness of chipboard.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1432-5225Source: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Summary The process of applying the rheological approach to describe creep deformation has been investigated using the 5-parameter model developed by Pierce and Dinwoodie (1977). A method utilising exponential curve fitting techniques was examined by attempting to produce fits to the first 6 months' data from long-term experiments (12 years). The procedure included a means of assessing the variability occurring in the derived model parameters which showed that acceptable fits were obtainable for only 3 out of the 20 data sets available. Further analysis of one of these data sets (that for cement-bonded particleboard, subjected to a stress level of 30% of the short-term ultimate in an environment of 25 °C and 90% relative humidity) revealed that the model attributed most of the creep deformation to the viscous component; resulting in an over-estimate of the deformation at 12 years when the 6-month fit was projected. An alternative approach to deriving the value of the model parameters is proposed, based on the theory underlying the model. The applicability of this approach was investigated using the above mentioned data set. It was found that the model can be constrained to give a more realistic ratio between the time-dependent components of deformation (ie. viscoelastic and viscous creep) for the material considered, thereby improving the accuracy of the projected creep deformation over the 12-year period.Type of Medium: Electronic ResourceURL: