Search Results - (Author, Cooperation:J. Mosley)

Showing 1 - 13 results of 13, query time: 0.20s Refine Results
  1. 1
    Staff View
    Publication Date:
    2014-10-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Enzyme Inhibitors/*pharmacology ; Humans ; Jumonji Domain-Containing Histone Demethylases/*antagonists & inhibitors ; Macrophages/*drug effects/*immunology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-07-31
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Biocatalysis/drug effects ; Catalytic Domain ; Cells, Cultured ; Enzyme Inhibitors/metabolism/*pharmacology ; Evolution, Molecular ; Histones/chemistry/metabolism ; Humans ; Inhibitory Concentration 50 ; Jumonji Domain-Containing Histone Demethylases/*antagonists & ; inhibitors/chemistry/classification/metabolism ; Lysine/metabolism ; Macrophages/*drug effects/enzymology/*immunology/metabolism ; Methylation/drug effects ; Mice ; Models, Molecular ; Substrate Specificity ; Tumor Necrosis Factor-alpha/biosynthesis
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-03-16
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Genetics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-12-15
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Celedón, J. C. ; Soto-Quiros, M. E. ; Palmer, L. J. ; Senter, J. ; Mosley, J. ; Silverman, E. K. ; Weiss, S. T.

    Oxford, UK : Blackwell Science, Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background IL-13 has been implicated in the pathogenesis of asthma and in the regulation of IgE synthesis in humans. Single nucleotide polymorphisms (SNPs) in the IL-13 gene have been associated with asthma and total serum IgE level in Caucasian populations.Objective To test for genetic association between an SNP in exon 4 of the IL-13 gene (IL-13 + 2044 or Arg130Gln) and total serum IgE level and asthma-related phenotypes in a population with high prevalence of asthma living in Costa Rica.Methods Family-based association study.Results Among 83 Costa Rican school children with asthma and their parents (249 individuals), there was no evidence of linkage disequilibrium between the IL-13 + 2044 SNP and any of the outcomes of interest (total serum IgE level on a logarithmic scale, number of positive skin tests to aeroallergens, and asthma). These results were not significantly changed after adjustment for age and gender.Conclusions No significant evidence of linkage disequilibrium between an SNP in exon 4 of the IL-13 gene and total serum IgE level, sensitization to allergens or asthma was found in a family-based association study in Costa Rica.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2222.2002.01348.x

    Articles: DFG German National Licenses
  6. 6
    MOSLEY, J. P.

    Chalfont St. Giles, U.K. : Periodicals Archive Online (PAO)
    Published 1973
    Staff View
    ISSN:
    0047-2441
    Topics:
    General, Interdisciplinary
    Notes:
    REVIEW NOTICES
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:h007-1973-003-01-000006

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0885-2006
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Education
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0885-2006(05)80067-5

    Articles: DFG German National Licenses
  8. 8
    MOSLEY, J. L.

    Sydney, N.S.W. : Periodicals Archive Online (PAO)
    Published 1983
    Staff View
    ISSN:
    0004-8402
    Topics:
    Philosophy
    Notes:
    DISCUSSIONS
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4251-1983-061-00-000027

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    0022-2836
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-2836(72)80042-1

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0885-2006
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Education
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0885-2006(92)90010-V

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0885-2006
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Education
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0885-2006(05)80067-5

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-0827
    Keywords:
    Loading ; Strain ; Modeling ; Rat ; Ulna
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Physics
    Notes:
    Abstract Adaptive changes in bone modeling in response to noninvasive, cyclic axial loading of the rat ulna were compared with those using 4-point bending of the tibia. Twenty cycles daily of 4-point bending for 10 days were applied to rat tibiae through loading points 23 and 11 mm apart. Control bones received nonbending loads through loading points 11 mm apart. As woven bone was produced in both situations, any strain-related response was confounded by the response to direct periosteal pressure. Four-point bending is not, therefore, an ideal mode of loading for the investigation of strain-related adaptive modeling. The ulna's adaptive response to daily axial loading over 9 days was investigated in 30 rats. Groups 1–3 were loaded for 1200 cycles: Group 1 at 10 Hz and 20 N, Group 2 at 10 Hz and 15 N, and Group 3 at 20 Hz and 15 N. Groups 4 and 5 received 12,000 cycles of 20 N and 15 N at 10 Hz. Groups 1 and 4 showed a similar amount of new bone formation. Group 4 showed the same pattern of response but in reduced amount. The responses in Groups 2 and 3 were either small or absent. Strains were measured with single-element, miniature strain gauges bonded around the circumference of dissected bones. The 20 N loading induced peak strains of 3500–4500 μstrain. The width of the periosteal new bone response was proportional to the longitudinal strain at each point around the bone's circumference. It appears that when a bone is loaded in a normal strain distribution, an osteogenic response occurs when peak physiological strains are exceeded. In this situation the amount of new bone formed at each location is proportional to the local surface strain. Cycle numbers between 1200 and 12,000, and cycle frequencies between 10 and 20 Hz have no effect on the bone's adaptive response.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00301686

    Articles: DFG German National Licenses
  13. 13
    Mosley, J. W.
    Springer
    Published 1967
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01240520

    Articles: DFG German National Licenses