Search Results - (Author, Cooperation:J. McNamara)
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1K. A. Oye ; K. Esvelt ; E. Appleton ; F. Catteruccia ; G. Church ; T. Kuiken ; S. B. Lightfoot ; J. McNamara ; A. Smidler ; J. P. Collins
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Animals, Genetically Modified/*genetics ; Caspase 9/genetics ; *Clustered Regularly Interspaced Short Palindromic Repeats ; Communicable Disease Control/*methods ; Culicidae/*genetics ; Dengue/prevention & control ; *Gene Expression Regulation ; Gene Targeting/methods ; Genetic Engineering/*methods ; Humans ; Malaria/parasitology/prevention & control ; Mosquito Control/*methods ; RNA/genetics ; Reproduction/genetics ; Risk ManagementPublished by: -
2Antonova-Koch, Y., Meister, S., Abraham, M., Luth, M. R., Ottilie, S., Lukens, A. K., Sakata-Kato, T., Vanaerschot, M., Owen, E., Jado Rodriguez, J. C., Maher, S. P., Calla, J., Plouffe, D., Zhong, Y., Chen, K., Chaumeau, V., Conway, A. J., McNamara, C. W., Ibanez, M., Gagaring, K., Serrano, F. N., Eribez, K., Taggard, C. M., Cheung, A. L., Lincoln, C., Ambachew, B., Rouillier, M., Siegel, D., Nosten, F., Kyle, D. E., Gamo, F.-J., Zhou, Y., Llinas, M., Fidock, D. A., Wirth, D. F., Burrows, J., Campo, B., Winzeler, E. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-12-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Chemistry, Microbiology, Online OnlyPublished by: -
3Bockmann, F. A., Rodrigues, M. T., Kohsldorf, T., Straker, L. C., Grant, T., de Pinna, M. C. C., Mantelatto, F. L. M., Datovo, A., Pombal, J. P., McNamara, J. C., de Almeida, E. A. B., Klein, W., Hsiou, A. S., Groppo, M., e Castro, R. M. C., de Souza Amorim, D.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-05-25Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Staff View
ISSN: 1471-6402Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: PsychologyNotes: Women are participating in the field of psychology in increasing numbers relative to men. This development has been referred to as the “feminization of psychology,” and it carries with it a number of implications. This article reviews statistical data relating to the changing sex ratio and discusses their implications. Participation rates of women in psychology are examined as they pertain to enrollment in doctoral programs, graduation from baccalaureate programs, and career progress within the profession. Implications of changing sex ratios for occupational prestige, income and economics, work structure, education and training, and theory, research, and practice are then discussed. In conclusion, the concept of “feminization” is challenged as questions are raised about whether the increase in the number of women in psychology is a problem, as has been alleged, or a symptom of other problems within the fieldType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract— Previous work from this and other laboratories has demonstrated phosphorylation of myelin BP in vivo and in vitro. The rapid turnover of BP phosphate has suggested the presence of a phosphatase. The present studies have identified two BP phosphatases. One is present in the cytosol of rat brain homogenate. It has the highest specific activity (37 pmol/min/mg) and total activity of BP phosphatase present in any subcellular fraction. The partially purified cytosol enzyme can readily dephosphorylate soluble 32P-labelled BP but is only half as effective in dephosphorylating membrane-bound BP. Conversely, the phosphatase which remains associated with highly purified myelin is 2.3 times as effective on BP in the membrane (7.2 pmol/min/mg) as on soluble BP (3.2 pmol/min/mg). The myelin phosphatase is tightly bound to the membrane and cannot be removed with concentrated salt solutions. During development the specific activity of the cytosol phosphatase remains constant. The specific activity of the myelin phosphatase, however, is twice as high during the period of maximum myelin formation (6.8 pmol/min/mg at 18 days) as it is in adult myelin (3.2 pmol/min/mg at 12 weeks).In order to compare enzyme effectiveness under the various conditions employed in these studies, we have assumed that both soluble and particulate substrates are phosphorylated at equivalent sites on the polypeptide. We have further assumed that soluble and/or particulate substrates are dephosphorylated at equivalent sites on the polypeptide chain and that the various particulate and soluble enzymes have comparable access to the substrate. Within the limitations of these assumptions, our data suggest myelin phosphatase may play a significant role in phosphate turnover of BP.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1469-7610Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Distorted underestimates (Pawlicki, 1970) of the scientific adequacy of behavior therapy research with children has resulted because appropriate design-criteria relationships were not considered in evaluating studies in this area. Eighty percent of the studies have appropriately incorporated the criteria of control group, baseline, and systematic variation of treatment into their designs. However, even when design-criteria relationships are considered, a number of criteria have been inadequately controlled for in a large percentage of studies. In fact, the criteria of unbiased observer and follow-up have, on the average, been controlled for in only 46 per cent of the studies reviewed. If the scientific merit of research in this area is to be accepted, then more attention to tightening controls on these variables is needed.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
9SHERRY, K. M. ; McNAMARA, J. ; BROWN, J. S. ; DRUMMOND, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A comparison was made of the drug costs and nursing dependency of patients undergoing elective cardiac surgery and routine postoperative recovery for two anaesthetic techniques using either propofol with low dose fentanyl or midazolam with high dose fentanyl. Estimates of resource use were based on a randomised clinical trial undertaken at the Northern General Hospital, Sheffield. Times from entry to the intensive care unit until extubation and discharge were recorded for 70 patients and were transformed to nursing shifts. Nursing dependency was calculated on the basis of one nurse per ventilated patient and 0.5 nurse from the start of the shift after extubation. Nursing costs were allocated on the basis of the patient's status at the beginning of each shift in line with the hospital's staffing policy. All drugs used from the morning of the operation until discharge were recorded. Costs of nursing and drugs were calculated. The total cost of patients in the propofol group was 13.3% less than midazolam patients (p = 0.043, for geometric means Cl 0.4% to 27.8%). The clinical study was not designed for economic endpoints; however, it demonstrated achievable savings in propofol-treated patients.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
11Jeltes, T. ; McNamara, J. M. ; Hogervorst, W. ; Krachmalnicoff, V. ; Schellekens, M. ; Perrin, A. ; Chang, H. ; Boiron, D. ; Aspect, A. ; Vassen, W. ; Westbrook, C. I.
[s.l.] : Nature Publishing Group
Published 2007Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Fifty years ago, Hanbury Brown and Twiss (HBT) discovered photon bunching in light emitted by a chaotic source, highlighting the importance of two-photon correlations and stimulating the development of modern quantum optics. The quantum interpretation of bunching relies on the constructive ...Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] IT is disputed whether the flight of flying-fish is a genuine flight or simply a leap and a glide. The question is referred to in the section devoted to flying-fish in the Natural History Museum, South Kensington. Recently I have had ample opportunity to study these fish in the tropical waters ...Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0005-7894Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0005-7894Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0022-5193Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0003-3472Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0040-5809Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: