Search Results - (Author, Cooperation:J. M. Kremer)
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1Latest Papers from Table of Contents or Articles in PressY. Okada ; D. Wu ; G. Trynka ; T. Raj ; C. Terao ; K. Ikari ; Y. Kochi ; K. Ohmura ; A. Suzuki ; S. Yoshida ; R. R. Graham ; A. Manoharan ; W. Ortmann ; T. Bhangale ; J. C. Denny ; R. J. Carroll ; A. E. Eyler ; J. D. Greenberg ; J. M. Kremer ; D. A. Pappas ; L. Jiang ; J. Yin ; L. Ye ; D. F. Su ; J. Yang ; G. Xie ; E. Keystone ; H. J. Westra ; T. Esko ; A. Metspalu ; X. Zhou ; N. Gupta ; D. Mirel ; E. A. Stahl ; D. Diogo ; J. Cui ; K. Liao ; M. H. Guo ; K. Myouzen ; T. Kawaguchi ; M. J. Coenen ; P. L. van Riel ; M. A. van de Laar ; H. J. Guchelaar ; T. W. Huizinga ; P. Dieude ; X. Mariette ; S. L. Bridges, Jr. ; A. Zhernakova ; R. E. Toes ; P. P. Tak ; C. Miceli-Richard ; S. Y. Bang ; H. S. Lee ; J. Martin ; M. A. Gonzalez-Gay ; L. Rodriguez-Rodriguez ; S. Rantapaa-Dahlqvist ; L. Arlestig ; H. K. Choi ; Y. Kamatani ; P. Galan ; M. Lathrop ; S. Eyre ; J. Bowes ; A. Barton ; N. de Vries ; L. W. Moreland ; L. A. Criswell ; E. W. Karlson ; A. Taniguchi ; R. Yamada ; M. Kubo ; J. S. Liu ; S. C. Bae ; J. Worthington ; L. Padyukov ; L. Klareskog ; P. K. Gregersen ; S. Raychaudhuri ; B. E. Stranger ; P. L. De Jager ; L. Franke ; P. M. Visscher ; M. A. Brown ; H. Yamanaka ; T. Mimori ; A. Takahashi ; H. Xu ; T. W. Behrens ; K. A. Siminovitch ; S. Momohara ; F. Matsuda ; K. Yamamoto ; R. M. Plenge
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-01-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Arthritis, Rheumatoid/*drug therapy/*genetics/metabolism/pathology ; Asian Continental Ancestry Group/genetics ; Case-Control Studies ; Computational Biology ; *Drug Discovery ; Drug Repositioning ; European Continental Ancestry Group/genetics ; Female ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Hematologic Neoplasms/genetics/metabolism ; Humans ; Male ; Mice ; Mice, Knockout ; *Molecular Targeted Therapy ; Polymorphism, Single Nucleotide/geneticsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1573-269XKeywords: Composite plates ; nonlinear vibration ; finite element method ; multibody dynamics ; stress analysis ; and numerical methodsSource: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Abstract The development of a shear-deformable laminated plate element, based on the Mindlin plate theory, for use in large reference displacement analysis is presented. The element is sufficiently general to accept an arbitrary number of layers and an arbitrary number of orthotrophic material property sets. Coordinate mapping is utilized so that non-rectangular elements may be modeled. The Gauss quadrature method of numerical integration is utilized to evaluate volume integrals. A comparative study is done on the use of full Gauss quadrature, reduced Gauss quadrature, mixed Gauss quadrature, and closed form integration techniques for the element. Dynamic analysis is performed on the RSSR (Revolute-Spherical-Spherical-Revolute) mechanism, with the coupler modeled as a flexible plate. The results indicate the differences in the dynamic response of the transverse shear deformable eight-noded element as compared to a four-noded plate element. Dynamically induced stresses are examined, with the results indicating that the primary deformation mode of the eight-noded Mindlin plate model being bending.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesKremer, J. M. ; Shabana, A. A. ; Widera, G. E. O.
Chichester [u.a.] : Wiley-Blackwell
Published 1993Staff ViewISSN: 0029-5981Keywords: Engineering ; Engineering GeneralSource: Wiley InterScience Backfile Collection 1832-2000Topics: MathematicsTechnologyNotes: This investigation concerns itself with the computer implementation of the dynamic formulation of thin laminated composite plates consisting of layers of orthotropic laminae that undergo large arbitrary rigid body displacements and small elastic deformations. A finite element preprocessor computer program is developed to automatically generate the invariants of the laminae, which may have arbitrary orientations. The laminae invariants are then used to obtain the invariants of the elements and the composite laminated plate. The consistent and lumped mass formulations of the invariants of motion of composite plates are compared and it is concluded that the two methods are comparable, if a fine enough finite element mesh is used. The structure of the dynamic equations of motion, based on the formulation presented in Part I of this paper, is examined. Non-linear centrifugal and Coriolis forces arising as the result of the finite rotations of the laminae are defined, and the solution schemes of the resulting non-linear differential equations of motion are discussed. Numerical examples illustrating the differences between homogeneous isotropic and laminated composite plates are presented. An RSSR (Revolute-Spherical-Spherical-Revolute) mechanism is used in the numerical examples, with the coupler modelled as a laminated plate flexible body. It is found that the inertia of the plate contributed greatly to the transverse deformation. The effects of laminae orientation is also investigated.Additional Material: 9 Ill.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesKremer, J. M. ; Shabana, A. A. ; Widera, G. E. O.
Chichester [u.a.] : Wiley-Blackwell
Published 1993Staff ViewISSN: 0029-5981Keywords: Engineering ; Engineering GeneralSource: Wiley InterScience Backfile Collection 1832-2000Topics: MathematicsTechnologyNotes: This investigation concerns itself with the dynamic analysis of thin, laminated composite plates consisting of layers of orthotropic laminae that undergo large arbitrary rigid body displacements and small elastic deformations. A non-linear finite element formulation is developed which utilizes the assumption that the bonds between the laminae are infinitesimally thin and shear non-deformable. Using the expressions for the kinetic and strain energies, the lamina mass and stiffness matrices are identified. The non-linear mass matrix of the lamina is expressed in terms of a set of invariants that depend on the assumed displacement field. By summing the kinetic and strain energies of the laminae of an element, the element mass and stiffness matrix can be defined in terms of the set of element invariants. It is shown that the element invariants can be expressed explicitly in terms of the invariants of its laminae. By assembling the finite elements of the deformable body, the body invariants can be identified and expressed explicitly in terms of the invariants of the laminae of its elements. In the dynamic formulation presented in this paper, the shape functions of the laminae are assumed to have rigid body modes that need to describe only large rigid body translations. The computer implementation and the use of the formulation developed in this investigation in multibody dynamics are discussed in the second part of this paper.Additional Material: 3 Ill.Type of Medium: Electronic ResourceURL: