Search Results - (Author, Cooperation:J. Levine)
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1Janaki Sheth, Sebastiaan W. F. Meenderink, Patricia M. Quiñones, Dolores Bozovic, and Alex J. Levine
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-06-19Publisher: American Physical Society (APS)Print ISSN: 1539-3755Electronic ISSN: 1550-2376Topics: PhysicsKeywords: Biological PhysicsPublished by: -
2Chandra, A., Wang, L., Young, T., Zhong, L., Tseng, W.-J., Levine, M. A., Cengel, K., Liu, X. S., Zhang, Y., Pignolo, R. J., Qin, L.
The Federation of American Societies for Experimental Biology (FASEB)
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: The Federation of American Societies for Experimental Biology (FASEB)Print ISSN: 0892-6638Electronic ISSN: 1530-6860Topics: BiologyPublished by: -
3Califano, J. A., Khan, Z., Noonan, K. A., Rudraraju, L., Zhang, Z., Wang, H., Goodman, S., Gourin, C. G., Ha, P. K., Fakhry, C., Saunders, J., Levine, M., Tang, M., Neuner, G., Richmon, J. D., Blanco, R., Agrawal, N., Koch, W. M., Marur, S., Weed, D. T., Serafini, P., Borrello, I.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-12-04Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4O. Simakov ; T. Kawashima ; F. Marletaz ; J. Jenkins ; R. Koyanagi ; T. Mitros ; K. Hisata ; J. Bredeson ; E. Shoguchi ; F. Gyoja ; J. X. Yue ; Y. C. Chen ; R. M. Freeman, Jr. ; A. Sasaki ; T. Hikosaka-Katayama ; A. Sato ; M. Fujie ; K. W. Baughman ; J. Levine ; P. Gonzalez ; C. Cameron ; J. H. Fritzenwanker ; A. M. Pani ; H. Goto ; M. Kanda ; N. Arakaki ; S. Yamasaki ; J. Qu ; A. Cree ; Y. Ding ; H. H. Dinh ; S. Dugan ; M. Holder ; S. N. Jhangiani ; C. L. Kovar ; S. L. Lee ; L. R. Lewis ; D. Morton ; L. V. Nazareth ; G. Okwuonu ; J. Santibanez ; R. Chen ; S. Richards ; D. M. Muzny ; A. Gillis ; L. Peshkin ; M. Wu ; T. Humphreys ; Y. H. Su ; N. H. Putnam ; J. Schmutz ; A. Fujiyama ; J. K. Yu ; K. Tagawa ; K. C. Worley ; R. A. Gibbs ; M. W. Kirschner ; C. J. Lowe ; N. Satoh ; D. S. Rokhsar ; J. Gerhart
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-11-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Chordata, Nonvertebrate/classification/*genetics ; Conserved Sequence/genetics ; Echinodermata/classification/genetics ; *Evolution, Molecular ; Genome/*genetics ; Multigene Family/genetics ; Phylogeny ; Signal Transduction ; Synteny/genetics ; Transforming Growth Factor betaPublished by: -
5Nahas, M. R., Soiffer, R. J., Kim, H. T., Alyea, E. P., Arnason, J., Joyce, R., Antin, J. H., Ho, V. T., Stroopinsky, D., Li, S., Levine, J. D., McMasters, M., Jain, S., Hamdan, A., Tzachanis, D., Bryant, M. P., Logan, E. K., Bazemore, J., Stewart, J., Joyce, A., Stephenson, S., Washington, A., Cole, L., Pyzer, A., Leaf, R. K., Avigan, D. E., Rosenblatt, J.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-06-22Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Transplantation, Clinical Trials and ObservationsPublished by: -
6Staff View
Publication Date: 2018-06-22Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Transplantation, Free Research Articles, CME article, Clinical Trials and ObservationsPublished by: -
7Staff View
Publication Date: 2018-04-13Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Free Research ArticlesPublished by: -
8Mueller, K. T., Waldron, E., Grupp, S. A., Levine, J. E., Laetsch, T. W., Pulsipher, M. A., Boyer, M. W., August, K. J., Hamilton, J., Awasthi, R., Stein, A. M., Sickert, D., Chakraborty, A., Levine, B. L., June, C. H., Tomassian, L., Shah, S. S., Leung, M., Taran, T., Wood, P. A., Maude, S. L.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-12-15Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
9Levine, J. S. ; Aiello, N. ; Benford, J. ; Harteneck, B.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We have achieved phase-locked operation of a module consisting of up to seven relativistic magnetrons. The magnetrons are connected by waveguide in a peer/peer configuration, with no one magnetron acting as a master oscillator. The signals used for coupling are each a substantial fraction of a magnetron's radiated power. Total extracted power, at 2.8 GHz, was 2.0 GW with four magnetrons and 2.9 GW with seven. Several interconnection geometries were explored. One particular geometry was found to produce qualitatively better phase-locked operation than any other. This was in agreement with the predictions of a numerical model of the magnetrons as coupled van der Pol oscillators.Type of Medium: Electronic ResourceURL: -
10Levine, J. S. ; Coleman, P. L. ; Failor, B. H. ; Riordan, J. C. ; Song, Y. ; Sze, H. M.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Solid-fill nozzles for long-implosion Z-pinch experiments to produce argon K-shell x rays (photon energy 〉3.1 keV) have been developed. With a 7 cm diam nozzle, which is appropriate for a 200 ns driver, stable implosions at 180 ns and 4 MA have produced peak argon K-shell yields exceeding 15 kJ. As previously seen with short (∼100 ns) implosion times, the K-shell yield scales as the fourth power of peak current, I4. Limited testing with a 10 cm nozzle, which is appropriate for a 〉250 ns driver, has also achieved a stable implosion. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11Sze, H. ; Coleman, P. L. ; Failor, B. H. ; Fisher, A. ; Levine, J. S. ; Song, Y. ; Waisman, E. M.
[S.l.] : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Recent observations are given for an argon double-shell gas puff imploded with up to 4 MA in 200 ns on the Double Eagle generator [G. B. Frazier et al., Digest of Technical Papers, Fourth IEEE Pulsed Power Conference (IEEE, Piscataway, NJ, 1983), p. 583]. Good K-shell x-ray output with good pinch quality was observed. A novel experimental procedure was used to selectively seed the inner or outer gas plenums with a chlorine tracer. The tracer data provide the first direct experimental evidence that the mass initially closest to the axis is the dominant contributor to the hot core of the radiating pinch. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Sze, H. ; Coleman, P. L. ; Banister, J. ; Failor, B. H. ; Fisher, A. ; Levine, J. S. ; Song, Y. ; Waisman, E. M.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The first observations of gaseous load implosions with over 15 MA in 〉110 ns on the Z generator [R. B. Spielman et al., Phys. Plasmas 5, 2105 (1998)] are reported. Starting from a diameter of over 8 cm, an argon double-shell Z pinch imploded to under 0.5 cm K-shell emission diameter. With a load mass of 0.8 mg/cm, K-shell x-ray output reached 274±24 kJ in a 15 TW peak power, 12 ns pulse. This record-high yield is consistent with the current-squared scaling predicted for the "efficient" emission regime. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Failor, B. H. ; Coleman, P. A. ; Levine, J. S. ; Song, Y. ; Sze, H. M.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: Timely estimates of z-pinch plasma conditions can aid in the optimization of plasma radiation source K-shell emission. For example, a shell-on-shell argon gas puff has many parameters, such as the axial gas density profile, inner to outer shell mass ratio, total mass, and pinch load length, which can be varied on a shot by shot basis. At the Double-EAGLE facility at Maxwell Physics International, digital cameras have been implemented to routinely record pinhole images, x-ray spectra, and axially resolved streak images. A computer algorithm has been implemented to take as input the data (pinch diameter, Ar Lyα to Heα line ratio, and K-shell power) and output the plasma parameters (density, electron temperature, and K-shell-emitting mass) as a function of z-pinch axial location. We describe the algorithm and present results for three different z-pinch loads. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
14Song, Y. ; Coleman, P. ; Failor, B. H. ; Fisher, A. ; Ingermanson, R. ; Levine, J. S. ; Sze, H. ; Waisman, E.
[S.l.] : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: We have developed a dual-plenum gas valve coupled to a double shell nozzle for the generation of "shell-on-shell" gas loads in z-pinch plasma radiation source experiments. The gas density profiles of the nozzles have been characterized with laser interferometry. This valve/nozzle combination has been successfully fielded on the Double-EAGLE and Saturn pulsed-power generators. The design and characterization of the shell-on-shell valve/nozzle are presented in this article. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
15Wong, S. ; Smiley, P. ; Sheridan, T. ; Levine, J. ; Buck, V.
[S.l.] : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The design of a fast-acting high-pressure puff valve for use in imploding gas-puff experiments is presented. By using a pressure-balanced valve design, the valve can operate at pressures up to 500 psia. Fast opening (≈200 μs) is achieved by using a fast-moving sliding hammer to open the valve. Balanced valves as well as fast-opening valves using sliding hammers are both well-known technologies; however, this design is the first one to incorporate both features in a single design resulting in a fast-acting high-pressure puff valve.Type of Medium: Electronic ResourceURL: -
16Failor, B. H. ; Coleman, P. L. ; Levine, J. S. ; Song, Y. ; Sze, H.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: Hardware and software have been developed for recording and displaying accurate image and spectral data produced by z-pinch plasma radiation sources at the Double-EAGLE facility at Maxwell Physics International. Desktop computers are used to acquire the data, analyze it, and display and print the results. Of the four charge-coupled device (CCD) image recording systems implemented, two record x rays directly and two record optical light emission from electron–excited phosphors. The CCD systems required careful shielding to allow them to operate in the harsh radio frequency noise environment. During a series of shots at the SATURN facility at Sandia National Laboratories, the quality of a keV x-ray spectrum recorded directly with a CCD compared well with an equivalent spectrum recorded with 2497 film. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
17Tambeli, C. H. ; Quang, P. ; Levine, J. D. ; Gear, R. W.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Noxious (i.e. painful) stimulation in the rat induces profound heterosegmental antinociception as demonstrated by the ability of either thermal stimulation (50 °C water) or subdermal capsaicin injection in the hindpaw to attenuate the nociceptive trigeminal jaw-opening reflex. Importantly, noxious stimulus-induced antinociception (NSIA) is mediated by endogenous opioids (as well as other neurotransmitters) in nucleus accumbens, as indicated by the ability of intra-accumbens administration of mu- or delta-opioid receptor antagonists to block NSIA. Although noxious peripheral stimulation is known to release excitatory neurotransmitters such as glutamate at the level of the spinal cord, the present study was designed to test the hypothesis that NSIA depends on further activation of spinal inhibitory receptors. This hypothesis was based on findings that inhibition of spinal processing (e.g. intrathecal local anaesthetic administration) also produces heterosegmental antinociception mediated by endogenous opioids in nucleus accumbens. Thus, to reconcile the paradoxical findings that both spinal excitation and inhibition appear to activate the same nucleus accumbens opioid-mediated antinociceptive mechanism, we investigated whether spinal administration of antagonists for inhibitory receptors would block the antinociceptive effect of subdermal capsaicin. We report that spinal administration of selective antagonists for mu-opioid (Cys2, Tyr3, Orn5, Pen7amide), kappa-opioid (nor-binaltorphimine), GABA-A (bicuculline), GABA-B (CGP 35348) and glycine (strychnine) receptors significantly reduced NSIA. The selective delta-opioid receptor antagonist naltrindole had no significant effect. These results, together with our previous findings, suggest that peripheral noxious stimuli release endogenous opioids, GABA and glycine in the spinal cord which, in turn, inhibit tonic pronociceptive spinal activity to produce heterosegmental antinociception mediated in nucleus accumbens.Type of Medium: Electronic ResourceURL: -
18DYKSTRA, M. J. ; LEVINE, J. F. ; NOGA, E. J. ; HAWKINS, J. H. ; GERDES, P. ; JR, W. J. HARGIS ; GRIER, H. J. ; STRAKE, D. TE
Oxford, UK : Blackwell Publishing Ltd
Published 1989Staff ViewISSN: 1365-2761Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
19Plesh, O. ; Curtis, D. ; Levine, J. ; Mccall Jr, W. D.
Oxford, UK : Blackwell Science Ltd
Published 2000Staff ViewISSN: 1365-2842Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Randomized clinical trials of amitriptyline will require data from pilot studies to be used for sample size estimates, but such data are lacking. This study investigated the 6-week and 1-year effectiveness of low dose amitriptyline (10–30 mg) for the treatment of patients with chronic temporomandibular disorder (TMD) pain. Based on clinical examination, patients were divided into two groups: myofascial and mixed (myofascial and temporomandibular joint disorders). Baseline pain was assessed by a Visual Analogue Scale (VAS) for pain intensity and by the McGill Pain Questionnaire (MPQ). Depression was assessed by the Beck Depression Inventory (BDI) short form. Patient assessment of global treatment effectiveness was obtained after 6 weeks and 1 year of treatment by using a five-point ordinal scale: (1) worse, (2) unchanged, (3) minimally improved, (4) moderately improved, (5) markedly improved. The results showed a significant reduction for all pain scores after 6 weeks and 1 year post-treatment. The depression scores changed in depressed but not in non-depressed patients. Global treatment effectiveness showed significant improvement 6 weeks and 1 year post-treatment. However, pain and global treatment effectiveness were less improved at 1 year than at 6 weeks.Type of Medium: Electronic ResourceURL: -
20Levine, J. E. ; Leontiadis, G. I. ; Sharma, V. K. ; Howden, C. W.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : Although a previous meta-analysis found that intravenous H2-receptor antagonists were only weakly beneficial in bleeding gastric ulcer and of no benefit in bleeding duodenal ulcer, patients with ulcer bleeding continue to receive such treatment.Aim : To re-evaluate the efficacy of intravenous H2-receptor antagonists in ulcer re-bleeding, surgery and mortality by updating the previous meta-analysis.Methods : After two independent literature searches, randomized, placebo-controlled trials of intravenous H2-receptor antagonists in bleeding ulcer published between 1984 and 2000 were added to those from the initial meta-analysis. Pooled rates of re-bleeding, surgery and death were re-calculated, together with the relative risk reduction, absolute risk reduction, number needed to treat and Mantel–Haenszel odds ratio.Results : Intravenous H2-receptor antagonists did not significantly reduce re-bleeding, surgery or death in bleeding duodenal ulcer. There were small but significant reductions in re-bleeding, surgery and death in bleeding gastric ulcer; the absolute risk reductions were 7.2%, 6.7% and 3.2%, respectively.Conclusions : Intravenous H2-receptor antagonists are of no value in bleeding duodenal ulcer, although they may be mildly beneficial in bleeding gastric ulcer. Because proton pump inhibitors have a greater inhibitory effect on gastric acid secretion than H2-receptor antagonists, they may be more effective in ulcer bleeding and should be further evaluated for that indication.Type of Medium: Electronic ResourceURL: