Search Results - (Author, Cooperation:J. L. Fink)

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  1. 1
    A. V. Biankin ; N. Waddell ; K. S. Kassahn ; M. C. Gingras ; L. B. Muthuswamy ; A. L. Johns ; D. K. Miller ; P. J. Wilson ; A. M. Patch ; J. Wu ; D. K. Chang ; M. J. Cowley ; B. B. Gardiner ; S. Song ; I. Harliwong ; S. Idrisoglu ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Wani ; M. Gongora ; M. Pajic ; C. J. Scarlett ; A. J. Gill ; A. V. Pinho ; I. Rooman ; M. Anderson ; O. Holmes ; C. Leonard ; D. Taylor ; S. Wood ; Q. Xu ; K. Nones ; J. L. Fink ; A. Christ ; T. Bruxner ; N. Cloonan ; G. Kolle ; F. Newell ; M. Pinese ; R. S. Mead ; J. L. Humphris ; W. Kaplan ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; A. Chou ; V. T. Chin ; L. A. Chantrill ; A. Mawson ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; R. J. Daly ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. Kakkar ; F. Zhao ; Y. Q. Wu ; M. Wang ; D. M. Muzny ; W. E. Fisher ; F. C. Brunicardi ; S. E. Hodges ; J. G. Reid ; J. Drummond ; K. Chang ; Y. Han ; L. R. Lewis ; H. Dinh ; C. J. Buhay ; T. Beck ; L. Timms ; M. Sam ; K. Begley ; A. Brown ; D. Pai ; A. Panchal ; N. Buchner ; R. De Borja ; R. E. Denroche ; C. K. Yung ; S. Serra ; N. Onetto ; D. Mukhopadhyay ; M. S. Tsao ; P. A. Shaw ; G. M. Petersen ; S. Gallinger ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; R. D. Schulick ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; P. Capelli ; V. Corbo ; M. Scardoni ; G. Tortora ; M. A. Tempero ; K. M. Mann ; N. A. Jenkins ; P. A. Perez-Mancera ; D. J. Adams ; D. A. Largaespada ; L. F. Wessels ; A. G. Rust ; L. D. Stein ; D. A. Tuveson ; N. G. Copeland ; E. A. Musgrove ; A. Scarpa ; J. R. Eshleman ; T. J. Hudson ; R. L. Sutherland ; D. A. Wheeler ; J. V. Pearson ; J. D. McPherson ; R. A. Gibbs ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-10-30
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Axons/*metabolism ; Carcinoma, Pancreatic Ductal/*genetics/*pathology ; Gene Dosage ; Gene Expression Regulation, Neoplastic ; Genome/*genetics ; Humans ; Kaplan-Meier Estimate ; Mice ; Mutation ; Pancreatic Neoplasms/*genetics/*pathology ; Proteins/genetics ; Signal Transduction
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    N. Waddell ; M. Pajic ; A. M. Patch ; D. K. Chang ; K. S. Kassahn ; P. Bailey ; A. L. Johns ; D. Miller ; K. Nones ; K. Quek ; M. C. Quinn ; A. J. Robertson ; M. Z. Fadlullah ; T. J. Bruxner ; A. N. Christ ; I. Harliwong ; S. Idrisoglu ; S. Manning ; C. Nourse ; E. Nourbakhsh ; S. Wani ; P. J. Wilson ; E. Markham ; N. Cloonan ; M. J. Anderson ; J. L. Fink ; O. Holmes ; S. H. Kazakoff ; C. Leonard ; F. Newell ; B. Poudel ; S. Song ; D. Taylor ; S. Wood ; Q. Xu ; J. Wu ; M. Pinese ; M. J. Cowley ; H. C. Lee ; M. D. Jones ; A. M. Nagrial ; J. Humphris ; L. A. Chantrill ; V. Chin ; A. M. Steinmann ; A. Mawson ; E. S. Humphrey ; E. K. Colvin ; A. Chou ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Pettitt ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. B. Jamieson ; J. S. Graham ; S. P. Niclou ; R. Bjerkvig ; R. Grutzmann ; D. Aust ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; M. Falconi ; G. Zamboni ; G. Tortora ; M. A. Tempero ; A. J. Gill ; J. R. Eshleman ; C. Pilarsky ; A. Scarpa ; E. A. Musgrove ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-02-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenocarcinoma/drug therapy/genetics ; Animals ; Carcinoma, Pancreatic Ductal/drug therapy/genetics ; *DNA Mutational Analysis ; DNA Repair/genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Markers/genetics ; Genome, Human/*genetics ; Genomic Instability/genetics ; *Genomics ; Genotype ; Humans ; Mice ; Mutation/*genetics ; Pancreatic Neoplasms/classification/drug therapy/*genetics ; Platinum/pharmacology ; Point Mutation/genetics ; Poly(ADP-ribose) Polymerase Inhibitors ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-05-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cohort Studies ; Cyclin E/genetics ; Cystadenocarcinoma, Serous/drug therapy/genetics ; DNA Methylation ; DNA Mutational Analysis ; DNA-Binding Proteins/genetics ; Drug Resistance, Neoplasm/*drug effects/*genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genes, Neurofibromatosis 1 ; Genome, Human/*genetics ; Germ-Line Mutation/genetics ; Humans ; Mutagenesis/genetics ; Oncogene Proteins/genetics ; Ovarian Neoplasms/drug therapy/*genetics ; P-Glycoprotein/genetics ; PTEN Phosphohydrolase/genetics ; Promoter Regions, Genetic/genetics ; Retinoblastoma Protein/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-04-05
    Publisher:
    Genetics Society of America (GSA)
    Print ISSN:
    0016-6731
    Topics:
    Biology
    Published by:
    http://www.genetics-gsa.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Jiang, J. ; Sharma, S. D. ; Hruby, V. J. ; Fink, J. L. ; Hadley, M. E.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1997
    Staff View
    ISSN:
    1600-0625
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract The objectives of this research were to determine whether melanotropin receptors are characteristic membrane markers of human epidermal melanocytes. Methodologies were developed to visualize these receptors by light microscopy. Multiple copies (up to a thousand) of [Nle4,D-Phe7]α-MSH, a superpotent analog of α-melanocyte stimulating hormone (α-MSH), were conjugated to a macromolecular carrier, large polyamide beads (macrospheres). Incubation in (the presence of the I conjugated macrospheres resulted in binding of human epidermal melanocytes to the macrospheres. Specificity of the binding of melanocytes of the melanotro-pin-conjugated macrospheres was demonstrated by several studies: (i) Binding of melanocytes to the conjugate was specific since it could be blocked by prior incubation of the cells in the presence of (the unconjugated hormone analog: (ii) The macrospheres after removal of the bound ligand did not bind to the melanocytes: (iii) Another peptide hormone ligand (e.g., a substance-P analog) attached to the macrospheres failed to bind to the melanocytes: (iv) BI6/F10 mouse melanoma cells known lo express melanotropin receptors bound to the macrospheres; (v) Cells of nomnelanocyte origin (e.g., mammary cancer cells, lung cancer cells, fibroblasts) did not bind lo the macrospheres. One exception was that human epidermal keratinocytes also expressed melanotropin receptors as determined by all the criteria established for epidermal melanocyles. Thus, cell specific melanotropin receptors appear to be characteristic cell surface markers of epidermal melanocytes and keratinocytes.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0625.1997.tb00139.x

    Articles: DFG German National Licenses