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Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-09-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Africa/ethnology ; Asia/ethnology ; Blood Pressure/*genetics/physiology ; Cardiovascular Diseases/*genetics ; Coronary Artery Disease/genetics ; Europe/ethnology ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Humans ; Hypertension/genetics ; Kidney Diseases/genetics ; Polymorphism, Single Nucleotide/*genetics ; Stroke/geneticsPublished by: -
2Staff View
ISSN: 1365-2095Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Determination of the optimal protein-to-energy ratio of fish feed is used as an example of how to improve the efficiency of experimental designs for feed formulation research. Studying one variable at a time is inefficient and lacks information on interactions between feed components. Even sound designs, such as full factorials, may fail in feed formulation studies because often two or more factors are implicitly confounded. A class of response surface methodology, namely designs for mixture experiments, is well suited for feed formulation problems and ensures that results are readily applicable to the feed industry. Combined with some criteria for searching the optimal runs for the experiment, mixture designs can improve the efficacy of resource use and diminish risks of inference and decision-making in fish feed research and development.Type of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 1434-3916Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We introduce a new method for fixation of a rare, isolated, proximal tibiofibular dislocation. One third of the biceps femoris muscle tendon was used for fixation of the dislocated proximal fibular head. The fixation was achieved by using a soft threaded interference ACL screw.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1432-1939Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary The relationship between the food selection of four leaf beetle species (Phratora vitellinae, Plagiodera versicolora, Lochmaea capreae, Galerucella lineola) and the phenolic glycosides of willow (Salix spp.) leaves was tested in laboratory food choice experiments. Four willow species native to the study area (Eastern Finland) and four introduced, cultivated willows were tested. The willow species exhibited profound differences in their phenolic glycoside composition and total concentration. The food selection patterns of the leaf beetles followed closely the phenolic glycoside spectra of the willow species. Both the total amount and the composition of phenolic glycosides affected the feeding by the beetles. Phenolic glycosides apparently have both stimulatory and inhibitory influences on leaf beetle feeding depending on the degree of adaptation of a particular insect. Very rare glycosides or exceptional combination of several glycoside types seem to provide certain willow species with high level of resistance against most herbivorous insects. Analogously the average absolute amount of leaf beetle feeding was lower on the introduced willows than on the native species to which the local herbivores have a good opportunity to become adapted.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1573-2959Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Abstract The hygienic quality of the water of the Kerava river, southern Finland, deteriorates occasionally. The purpose of the study was to design a real-time monitoring system that would inform the public using the river for recreational purposes about the changes in water quality. The system was constrained to consist of on-line sensing of water quality and quantity, and adjacent forecasting models. Four different system alternatives were analyzed and compared. The first alternative observes river flow in real-time; the second alternative also monitors water temperature, turbidity, pH, conductivity and dissolved oxygen. The data collected in this way are used to forecast Streptococcus and E. coli concentrations, using canonical correlation and regression analysis. The third configuration is a two-step procedure, where river flow is first predicted by an ARMAX model and the hygienic state is then based on the flow estimate, as in the first assemblage. The most expensive monitoring system, which at present is the least well-known, is to apply the Lidar system, where the hygienic status of the river quality is observed directly using laser technology, placing less emphasis on modeling. In this paper, the alternatives are formulated and a preliminary comparison is made, using the criteria of operational feasibility, prediction uncertainty, investment and maintenance costs, and suitability for in-situ monitoring.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1573-5117Keywords: observational design ; modelling ; estimation ; algal competion ; cyanobacteriaSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract An observational design technique supporting water quality modelling was reviewed and evaluated. The practical feasibility and mathematical sensitivity of the method were analysed for Lake Kuortaneenjärvi, Western Finland. A sampling programme to estimate characteristic rate parameters for competition between the nitrogen-fixing cyanobacter Aphanizomenon flos-aquae and eukaryotic phytoplankton was produced and the robustness of the design with respect to parameters and input was studied using the Monte Carlo technique. Optimal timing of observations appeared to be more sensitive to noise in the parameter values than to stochasticity in the model input, which consisted of data on the nutrient loading and climatic conditions of the lake. The perturbated parameter values favoured the weighting of phytoplankton dynamics, whereas the perturbations of the input shifted the design towards cyanobacterial dominance. It was concluded that this was because correct timing of algal succession was the most crucial element in successful estimation. Considerable rationalization of the use of measurement resources can be achieved by adopting the design procedure. This was also demonstrated for Lake Kuortaneenjärvi.Type of Medium: Electronic ResourceURL: