Search Results - (Author, Cooperation:J. Ke)

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  1. 1
    Y. Kang ; X. E. Zhou ; X. Gao ; Y. He ; W. Liu ; A. Ishchenko ; A. Barty ; T. A. White ; O. Yefanov ; G. W. Han ; Q. Xu ; P. W. de Waal ; J. Ke ; M. H. Tan ; C. Zhang ; A. Moeller ; G. M. West ; B. D. Pascal ; N. Van Eps ; L. N. Caro ; S. A. Vishnivetskiy ; R. J. Lee ; K. M. Suino-Powell ; X. Gu ; K. Pal ; J. Ma ; X. Zhi ; S. Boutet ; G. J. Williams ; M. Messerschmidt ; C. Gati ; N. A. Zatsepin ; D. Wang ; D. James ; S. Basu ; S. Roy-Chowdhury ; C. E. Conrad ; J. Coe ; H. Liu ; S. Lisova ; C. Kupitz ; I. Grotjohann ; R. Fromme ; Y. Jiang ; M. Tan ; H. Yang ; J. Li ; M. Wang ; Z. Zheng ; D. Li ; N. Howe ; Y. Zhao ; J. Standfuss ; K. Diederichs ; Y. Dong ; C. S. Potter ; B. Carragher ; M. Caffrey ; H. Jiang ; H. N. Chapman ; J. C. Spence ; P. Fromme ; U. Weierstall ; O. P. Ernst ; V. Katritch ; V. V. Gurevich ; P. R. Griffin ; W. L. Hubbell ; R. C. Stevens ; V. Cherezov ; K. Melcher ; H. E. Xu
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Arrestin/*chemistry/*metabolism ; Binding Sites ; Crystallography, X-Ray ; Disulfides/chemistry/metabolism ; Humans ; Lasers ; Mice ; Models, Molecular ; Multiprotein Complexes/biosynthesis/chemistry/metabolism ; Protein Binding ; Reproducibility of Results ; Rhodopsin/*chemistry/*metabolism ; Signal Transduction ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    F. Zhang ; J. Yao ; J. Ke ; L. Zhang ; V. Q. Lam ; X. F. Xin ; X. E. Zhou ; J. Chen ; J. Brunzelle ; P. R. Griffin ; M. Zhou ; H. E. Xu ; K. Melcher ; S. Y. He
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-08-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Motifs ; Apoproteins/chemistry/metabolism ; *Arabidopsis/chemistry/metabolism ; Arabidopsis Proteins/*antagonists & inhibitors/*chemistry/genetics/*metabolism ; Binding, Competitive/genetics ; Crystallography, X-Ray ; Cyclopentanes/*metabolism ; Models, Molecular ; Nuclear Proteins/metabolism ; Oxylipins/*metabolism ; Plant Growth Regulators/*metabolism ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding/genetics ; Protein Conformation ; Repressor Proteins/*chemistry/genetics/*metabolism ; *Signal Transduction ; Trans-Activators/*antagonists & inhibitors/*chemistry/genetics/metabolism ; Ubiquitination
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    C. Chen ; J. Ke ; X. E. Zhou ; W. Yi ; J. S. Brunzelle ; J. Li ; E. L. Yong ; H. E. Xu ; K. Melcher
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-07-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Binding Sites/genetics ; Crystallography, X-Ray ; Folate Receptor 1/*chemistry/genetics/*metabolism ; Folic Acid/chemistry/*metabolism ; Humans ; Ligands ; Models, Molecular ; Mutation ; Protein Binding ; Structure-Activity Relationship
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Ping, Y. ; Yu, C. X. ; Xie, J. L. ; Ke, J. ; Hu, X. W. ; Li, H. ; Ding, W. X.

    [S.l.] : American Institute of Physics (AIP)
    Published 2001
    Staff View
    ISSN:
    1089-7674
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The role of energetic electrons in periodic self-oscillations of a discharge plasma has been studied by measuring the spatiotemporal evolution of plasma potential, electron density, and electron velocity distribution function. It is found that the self-oscillation involves the instabilities of sheaths, propagation of a double layer and competition between the ionization, thermalization, and diffusion. The energetic electrons are the key factor which links these processes to form the oscillation cycle. The time interval of each phase in the cycle is estimated according to the physical process and the calculations are in agreement with experimental measurements. The study of the probe perturbation effect on the oscillations indicates that the length of the oscillation period is related to the amount of energetic electrons; the more energetic electrons, the shorter the period. © 2001 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0378-4347
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Wang, L. ; Ke, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0143-8166
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1352-8661
    Keywords:
    EPR ; oximetry ; in vivo ; biocompatibility ; ischemia ; MRI
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Physics
    Notes:
    Abstract The development of oxygen-sensitive paramagnetic materials is being actively pursued because of their potential applications forin vivo electron paramagnetic resonance (EPR) oximetry. Among these materials, fusinite is of particular interest because of the high sensitivity of the EPR linewidth to the partial pressure pO2. Although this material has led to a number of very useful results in experimental systems, its potential use in humans is limited by the need to prove that it will not cause deleterious effects. The strategy used in this study to optimize the biocompatibility of the oxygen-sensitive materials was to prepare small silicon implants containing the fusinite. The use of silicon permits the diffusion of oxygen inside the implant while the material does not have contact with the biological environment. Radiosterilization did not affect the pO2 sensitivity of the material. The feasibility of performing pO2 measurement was verifiedin vivo by perodically inducing ischemia in the gastrocnemius muscle of mice over a period of 6 weeks.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Ke, J. S. ; Liu, H. W.
    Springer
    Published 1971
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Gavigan, W. J. ; Ke, J. S. ; Liu, H. W.
    Springer
    Published 1973
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents:
    Résumé Les déformations locales au voisinage de l'extrémité d'une entaille ont été étudiées dans le cas d'éprouvettes fissurées sollicitées au delà de la limite élastique. Les COD et les dilatations près de l'entaille on été mesurées par la technique du Moiré. On a également mesuré les dilatations d'ensemble dans la section fissurée, et l'on a trouvé que ces trois quantités sont liées l'une à l'autre par des relations linéaires. Les distributions des déformations en surface près d'une fissure sont influencées par la striction locale à l'extrémité de la fissure, qui est sous la dépendence de l'épaisseur de la tôle.
    Abstract:
    Zusammenfassung Die lokalen Verformungen in der Umgebung der Spitze eines Kerbes wurden für den Fall einer gerissenen, und Beanspruchungen oberhalb der Elastizitätsgrenze ausgesetzten Probe, untersucht. Die COD und die Dehnungen in der Umgebung des Kerbes wurden nach dem Moiré-Verfahren bestimmt. Außerdem wurden die Gesamtdehnungen in der gerissenen Ebene gemessen. Es ergab sich ein linearer Zusammenhang zwischen diesen drei Größen. Die Verteilung der Verformungen an der Oberfläche in der Nähe eines Risses werden durch die lokale Einschnürung and der Rißspitze beinflußt. Letztere hängt ihrerseits von der Dicke des Bleches ab.
    Notes:
    Abstract The local deformation near a crack tip were investigated when a cracked specimen was stressed beyond general yielding. Crack opening displacements, and near tip strains were measured by the moire technique. The gross elongation in the cracked-section was also measured. These three quantities were found to be linearly related to each other. Surface strain distributions near a crack are influenced by the local necking at the crack tip, which is controlled by the plate thickness.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Liu, H. W. ; Gavigan, William J. ; Ke, J. S.
    Springer
    Published 1970
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents:
    Résumé Comme critère pour la rupture ductile, on suggère d'adopter une déformation critique à une courte distance de la pointe d'une fissure. Les déformations en surface ont été mesurées, à l'aide de la méthode du moiré, sur des éprouvettes fissurées d'alliage d'Aluminium 2024-0 comportant deux entailles latérales. La déformation le long de la ligne de fissuration, et au voisinage de la pointe de la fissure, est proportionnelle á l'allongement de la section droite fissurée, quantité mesurable pour caractériser les ruptures ductiles. On a analysé l'influence des dimensions de l'éprouvette sur la résistance à la rupture et sur l'énergie qu'elle absorbe. L'analyse proposée dans cc mémoire est qualitativement en accord avec résultats d'essais de rupture sur tin acier 4340 normalisé et sur l'alliage d'Aluminium 2024-T351.
    Abstract:
    Zusammenfassung Als Kriterium für das Verformungsverhalten wird die kritische Debuting in der Nähe einer Rissspitze vorgeschlagen. An einer mit zwei seitlichen Kerben gerissenen Probe aus einer Aluminium 2024-0 Legierung wurde die Oberflächen-dehnung nach dem moire Interferenzverfahren gemessen. Die Verformung entlang des Risslinie and in der näheren Umgebung der Rissspitze ist der Verlängerung des gerissenen Querschnitts proportional. Letztere wird als messbare Grösse zur Beschreibung des Verformungsbruchverhaltens herangezogen. Es wurde der Einfluss der Probenabmessungen auf die Zugfestigkeit and die absorbierte Energie ermittelt.
    Notes:
    Abstract A critical strain at a small distance from a crack tip is proposed as a ductile fracture criterion. Surface strain in double edge cracked specimen made of 2024-0 aluminum alloy was measured using the moiré method. The strain along the crack line and near a crack tip is proportional to the cracked-section-elongation, the latter is used as a measurable quantity to characterize ductile fractures. The effect of specimen size on fracture strength and energy absorption by the specimen were analyzed. The proposed ductile fracture analysis agrees qualitatively with fracture tests on fully annealed 4340 steel and 2024-T351 aluminum.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Schaeffer, B. J. ; Liu, H. W. ; Ke, J. S.
    Springer
    Published 1971
    Staff View
    ISSN:
    1741-2765
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract When a tensile stress is applied to a thin cracked plate, a strip necking region results ahead of a crack tip. The relative opening displacement between the crack surfaces and between the upper and lower boundaries of the strip necking region were measured by the moiré method. The strains ahead of the strip necking region and the thickness reduction (therein) were also measured. The measured relative opening displacements were compared with the calculated values using the Dugdale strip necking model. The thickness reduction in the strip necking region is equal to the relative opening displacement.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses