Search Results - (Author, Cooperation:J. K. Lim)
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1W. Shim ; A. B. Braunschweig ; X. Liao ; J. Chai ; J. K. Lim ; G. Zheng ; C. A. Mirkin
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-01-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Staff View
ISSN: 0167-4781Keywords: Interferon receptor ; Protein crosslinking ; cDNA sequence ; α-InterferonSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 0014-5793Keywords: Interferon α ; Interferon α receptor ; Xenopus laevis oocyteSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
4O'Hare, K. ; Tam, J. L. Y. ; Lim, J. K. ; Yurchenko, N. N. ; Zakharov, I. K.
Springer
Published 1998Staff ViewISSN: 1617-4623Keywords: Key wordsDrosophila melanogaster ; singed-49 ; hobo ; Transposable elements ; Chromosome rearrangementsSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The cytological structure of the X chromosome and the DNA organisation of the singed locus were examined in five singed bristle mutants of Drosophila melanogaster. These mutants are all derived from the unstable mutant singed-49, isolated from a wild population in the Russian Far East in 1975. Rearrangements were found at a site within the first intron of the singed gene, where a hobo element is inserted in these mutants. One rearrangement, which is associated with a strong bristle phenotype, has an inversion between 2D and the location of singed at 7D, which separates the singed promoter from the singed coding region. Two phenotypically wild-type derivatives have smaller rearrangements within the first intron which do not appear to interfere with singed expression. Two derivatives with bristle phenotypes have more complex rearrangements, and one of them shows a dominant or antimorphic phenotype. DNA blotting and in situ hybridisation experiments show that, in addition to these rearrangements at a hobo element inserted at singed, other hobo elements in these strains have been mobilised. This system is therefore similar to others in which functional hobo elements continue to transpose, resulting in elevated rates of mutation and chromosome rearrangement.Type of Medium: Electronic ResourceURL: