Search Results - (Author, Cooperation:J. Houck)
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1Latest Papers from Table of Contents or Articles in PressWu, Y., Liu, W., Zhou, Y., Hilton, T., Zhao, Z., Liu, W., Wang, M., Yeon, J., Houck, K., Thiagarajan, P., Zhang, F., Shi, F.-D., Wu, X., Li, M., Dong, J.-f., Zhang, J.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-09-07Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Thrombosis and Hemostasis, Vascular BiologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressQ. D. Wang ; M. A. Nowak ; S. B. Markoff ; F. K. Baganoff ; S. Nayakshin ; F. Yuan ; J. Cuadra ; J. Davis ; J. Dexter ; A. C. Fabian ; N. Grosso ; D. Haggard ; J. Houck ; L. Ji ; Z. Li ; J. Neilsen ; D. Porquet ; F. Ripple ; R. V. Shcherbakov
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-08-31Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The use of controlled-clearance piston gauges as highly accurate primary pressure standards is well established. However, the operation of a controlled-clearance gauge is more complicated than that of the familiar simple or reentrant designs. An investigation has been performed on a modified design of a piston gauge for which the same piston/cylinder can be operated in either the controlled-clearance, simple, or reentrant modes, to determine the degree of degradation in accuracy of measured pressure using the gauge in either the simple or reentrant modes as a standard. How the particular characterization of the standard gauge affects the calibration parameters of a test gauge is also explored. The effective areas of the test gauge are within 4.5 parts per million (ppm) when the standard is used in the simple mode instead of the controlled-clearance mode, up to a pressure of 28 MPa, whereas in the case of the reentrant mode this deviation increases from 2.5 ppm at 7 MPa to 14 ppm at 26 MPa.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesBohac, C. J. ; Hull, C. ; Forrest, William J. ; Furlan, E. ; Najita, J. ; Calvet, Nuria ; d’Alessio, Paola ; Hartmann, Lee ; Sargent, B. ; Green, Joel D. ; Kim, Kyoung Hee ; Houck, J. R. ; Watson, Dan M.
[s.l.] : Nature Publishing Group
Published 2007Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Class 0 protostars, the youngest type of young stellar objects, show many signs of rapid development from their initial, spheroidal configurations, and therefore are studied intensively for details of the formation of protoplanetary disks within protostellar envelopes. At millimetre ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] SINCE the announcement by Hench et al.1 of the dramatic effects of adrenal corticosteroids on. patients with 'collagen diseases', considerable interest has been expressed in the effects of corticosteroids on the collagen composition of the connective tissue.. Chemical studies2 have shown that the ...Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesDermott, S. F. ; Nicholson, P. D. ; Burns, J. A. ; Houck, J. R.
[s.l.] : Nature Publishing Group
Published 1984Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Measurements of longitudinal variations in the brightness and the latitude of the Solar System dust bands observed by the Infrared Astronomical Satellite determine the orbital elements of the particles involved. They may also allow discrimination between cometary and asteroidal models of the origin ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesPIPHER, JUDITH L. ; HOUCK, J. R. ; JONES, BARRIE W. ; HARWIT, MARTIN
[s.l.] : Nature Publishing Group
Published 1971Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Previous measurements in the 0.4-1.3 mm range1'2 yielded the unexpectedly strong submillimetre flux of 5^.5 x 10~9 W cm"2 sr"1. Subsequent detector recalibration3 lowered this value to 2.5!iJxlO-9 W cm-2 sr-1. Even with the recalibration, however, this flux corresponded to an energy density of 6.5 ...Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We have compared the properties of lymph node extracts from rat tissue with the properties of the supernatant obtained from the lectin-transformed rabbit peritoneal exudate lymphocytes in culture. Both extracts possess large amounts of lysosomal hydrolases, including particularly a cathepsin D-like protease. Both extracts are capable of increasing cutaneous permeability in the rat and causing a significant amount of cellular infiltration into the site of injection in the skin of these animals. This permeability-increasing activity and the cellular infiltration response to injection of these materials is completely inhibited by pepstatin and not by a variety of other inhibitors. Both extracts' permeability-increasing activity has a molecular weight range between 50,000 and 100,000 daltons and an isoelectric point of approximately 4.2. The molecular weight, the isoelectric point, and the inhibition by pepstatin are characteristic of cathepsin D from liver or spleen or granulocytes. Like cathepsin D, the permeability factor from LNPF and SRF extracts will release acid kinins from substrates which have been shown by Greenbaum and Houck to exist in the ground substance of rat skin. Finally, the breakdown products of the hydrolytic action of cathepsin D-like enzymes found in both lymph node extracts and supernatant from transformed lymphocytes are chemotactic for white blood cells. Thus, the two properties of cathepsin D described above, namely (a) the release of acid kinins which are capable of increasing the permeability of the microcirculation, and (b) the generation of chemotactic breakdown products via proteolysis could explain the two primary biological effects of both lymph node permeability factor and skin reactive factor.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Evidence is presented to indicate that there exists in lymphoid tissue, as a result of transforming lymphocytes, a new lymphokine which is chemotactically specific for lymphocytes, called ‘lymphotactin’. Lymphotactin has been purified to electrophoretic homogeneity; has a molecular weight of 10,500 D and an isoelectric point of 5.9. Its role in amplifying the immune defense system by recruitment of naive lymphocytes into propinquity with the challenging antigen is suggested. Purification of macrophage migration inhibitory factor from thymus extracts to electrophoretic homogeneity leads to a compound of molecular weight of 36,500 D and an IEP of 6.9. Chemically it contains sialic acid ando-methyl glucopyranoside as its only carbohydrates. Purified MIF activates the macrophage phagocytically. Skin reactive factor and lymph node permeability factor have been isolated and purified and are found to be inhibited by pepstatin and antihistamine and to have an isoelectric point of pH 4.2 and a molecular weight of 50,000–100,000 D. It is believed that this anionic permeability increasing agent actually arises from the lysosomes of macrophages and lymphoblasts (the normal small lymphocyte having essentially no lysosomal organelles). The mononuclear cell infiltration characteristic of crude SRF and LNPF may proceed from their being contaminated with lymphotactin.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesCleve, J. E. ; Hayward, T. L. ; Miles, J. W. ; Gull, G. E. ; Schoenwald, J. ; Houck, J. R.
Springer
Published 1994Staff ViewISSN: 1572-946XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract T Tauri stars are young stars usually surrounded by dusty disks similar to the one from which we believe our own Solar System formed. Most T Tauri stars exhibit a broad emission or absorption band between 7.5 and 13.5µm which is attributed to silicate grains in the circumstellar environment. We imaged three spatially resolved T Tauri binaries through a set of broadband filters which include the spectral region occupied by the silicate band. Two of these objects (T Tauri and Haro 6–10) are “infrared companion” systems in which one component is optically much fainter but contributes strongly in the infrared. Both infrared companions exhibit a deep silicate absorption which is not present in their primaries, indicating that they suffer very strong local extinction which may be due to an edge-on circumstellar disk or to a dense shell. We also took low resolution spectra of the silicate feature of two unresolved T Tauris to look for narrow features in the silicate band which would indicate the presence of specific minerals such as olivine. We observed GK Tau, for which Cohen and Witteborn (1985) reported a narrow emission feature at 9.7µm, but do not find evidence for this feature, and conclude that it is either time-dependent or an artifact of absorption by telluric ozone.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1573-2576Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Both crude and highly purified testicular hyaluronidase preparations have been shown to contain a component which increases the permeability of the microcirculation in rat skin. This permeability activity had an isoelectric point of 7.4 while hyaluronidase was 9.4. It also could be separated from hyaluronidase by acrylamide gel electrophoresis. The permeability factor was not inhibited by serum and may explain previous observations that hyaluronidase preparations decrease the ischemia and necrosis appropriate to experimental myocardial infarction in vivo.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1573-2576Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Pulmonary macrophage growth factor (MGF) can be purified from the “used” serum-free medium of cultures of mouse lung cells by concentration and dialysis over a 30,000-dalton Amicon ultrafilter and subjecting the retentate to isoelectric focusing. This yields a protein fraction with an isoelectric point of pH 4.2, which contains all the MGF activity. Upon electrophoresis of this fraction in analytical gels, one large and four small bands could be visualized. All bands were biologically active. This same “heterogenous” fraction ran as one band (mol wt 68,000) in SDS analytical gel electrophoresis, suggesting the ordered aggregation of this monomer. This was confirmed by reelectrophoresis of the first (and largest) band demonstrating the same 5-banded pattern as the initial material.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1572-9508Keywords: H II regionsSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We discuss preliminary results of an 11.7 μm imaging survey of ultracompact H II regions from the Wood and Churchwell radio survey. We find that that the morphologies of ionized gas and warm dust are often significantly different, indicating that an H II region classification scheme should be based on more than radio data.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1572-9508Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We have produced high-resolution images of the nuclear region of M82 with SpectroCam-10, a mid-infrared instrument at the Palomar 5 m telescope. These images were taken at 11.7 μm and 9.8 μm with a 1μm filter bandpass at the diffraction limit of 0.6 arcsec, making them the highest resolution maps yet available of M82. In addition, we have obtained high-resolution (λ/Δλ=2000) maps of the velocity field of the nuclear disk of M82 in the 12.81 μm line emission of [NeII]. In these proceedings we present the 11.7 μm image, which will appear together with the 9.8 μm map and the [Ne II] spectra in a subsequent paper, now in preparation. This image shows very clearly a bridge structure joining the eastern and western clusters.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0449-2978Keywords: Physics ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyPhysicsNotes: The results of bulk modulus and density measurements on low-density polyethylene to 30 kbar are presented. From these data the pressure coefficient dTt/dp of the glass transition temperature is obtained, and a comparison is made with data calculated from Pastine's theoretical equation of state for polyethylene.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0021-9541Keywords: Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyMedicineNotes: Six diploid human fibroblast strains were grown in confluent monolayers. Holes were scraped in these monolayers and the number of cells proliferating into these “wounds” with time were determined. The migration and mitotic aspects of the proliferation of fibroblasts into these wounds were analyzed separately.Small amounts of undialysed or dialysed serum were essential for cell division but not migration. Saline extracts of skin could not substitute for serum in the medium. Neither zinc nor cupric ion at tolerable concentrations (10-5M) increased the rate of cell proliferation.Normal human fibroblasts did not immediately start to divide from confluency into the “wound” space. Their generation time was about 32-39 hours. Fibroblasts from patients with cystic fibrosis began to divide almost immediately into the “wounded” area. Their generation time was about 48 to 56 hours.Additional Material: 3 Ill.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 0021-9541Keywords: Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyMedicineNotes: We have found that diploid human fibroblasts, but not heteroploid human fibroblasts, stringently required serum for their multiplication. Using Diaflo ultrafiltration membrane units, isoelectric focusing and preparative gel electrophoresis, we have isolated and purified this mitogenic activity from mammalian sera. This electrophoretically homogeneous sialoprotein is 120,000 daltons in size, with an iso-electric point of pH 5.2-5.4; it is made up of two electrophoretically identical dimers weighing 57,000 each; it is thermostable and is inactivated by both trypsin and neuraminidase.Additional Material: 5 Ill.Type of Medium: Electronic ResourceURL: