Search Results - (Author, Cooperation:J. Hayward)
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1Latest Papers from Table of Contents or Articles in PressMohamed M. Aboelnga, John J. Hayward and James W. Gauld
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-01-12Publisher: American Chemical Society (ACS)Electronic ISSN: 1520-5207Topics: Chemistry and PharmacologyPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressCoombs, C. C., Gillis, N. K., Tan, X., Berg, J. S., Ball, M., Balasis, M. E., Montgomery, N. D., Bolton, K. L., Parker, J. S., Mesa, T. E., Yoder, S. J., Hayward, M. C., Patel, N. M., Richards, K. L., Walko, C. M., Knepper, T. C., Soper, J. T., Weiss, J., Grilley-Olson, J. E., Kim, W. Y., Earp, H. S., Levine, R. L., Papaemmanuil, E., Zehir, A., Hayes, D. N., Padron, E.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-12-04Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressA. S. Allen ; S. F. Berkovic ; P. Cossette ; N. Delanty ; D. Dlugos ; E. E. Eichler ; M. P. Epstein ; T. Glauser ; D. B. Goldstein ; Y. Han ; E. L. Heinzen ; Y. Hitomi ; K. B. Howell ; M. R. Johnson ; R. Kuzniecky ; D. H. Lowenstein ; Y. F. Lu ; M. R. Madou ; A. G. Marson ; H. C. Mefford ; S. Esmaeeli Nieh ; T. J. O'Brien ; R. Ottman ; S. Petrovski ; A. Poduri ; E. K. Ruzzo ; I. E. Scheffer ; E. H. Sherr ; C. J. Yuskaitis ; B. Abou-Khalil ; B. K. Alldredge ; J. F. Bautista ; A. Boro ; G. D. Cascino ; D. Consalvo ; P. Crumrine ; O. Devinsky ; M. Fiol ; N. B. Fountain ; J. French ; D. Friedman ; E. B. Geller ; S. Glynn ; S. R. Haut ; J. Hayward ; S. L. Helmers ; S. Joshi ; A. Kanner ; H. E. Kirsch ; R. C. Knowlton ; E. H. Kossoff ; R. Kuperman ; S. M. McGuire ; P. V. Motika ; E. J. Novotny ; J. M. Paolicchi ; J. M. Parent ; K. Park ; R. A. Shellhaas ; J. J. Shih ; R. Singh ; J. Sirven ; M. C. Smith ; J. Sullivan ; L. Lin Thio ; A. Venkat ; E. P. Vining ; G. K. Von Allmen ; J. L. Weisenberg ; P. Widdess-Walsh ; M. R. Winawer
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Child Development Disorders, Pervasive ; Cohort Studies ; Exome/genetics ; Female ; Fragile X Mental Retardation Protein/metabolism ; Genetic Predisposition to Disease/genetics ; Humans ; Infant ; Intellectual Disability/*genetics/physiopathology ; Lennox Gastaut Syndrome ; Male ; Mutation/*genetics ; Mutation Rate ; N-Acetylglucosaminyltransferases/genetics ; Probability ; Receptors, GABA-A/genetics ; Spasms, Infantile/*genetics/physiopathologyPublished by: -
4Articles: DFG German National LicensesUBBINK, JOHAN B. ; VERMAAK, W. J. HAYWARD ; DELPORT, RHENA ; SERFONTEIN, WILLEM J. ; BARTEL, PETER
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesUBBINK, JOHAN B. ; DELPORT, RHENA ; VERMAAK, W. J. HAYWARD
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1477-7053Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1468-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Inflammation and the resulting accumulation of reactive oxygen species (ROS) play an important role in the intrinsic and photoaging of human skin in vivo. Environmental insults such as ultraviolet (UV) rays from sun, cigarette smoke exposure and pollutants, and the natural process of aging contribute to the generation of free radicals and ROS that stimulate the inflammatory process in the skin. UV irradiation initiates and activates a complex cascade of biochemical reactions in human skin. In short, UV causes depletion of cellular antioxidants and antioxidant enzymes (SOD, catalase), initiates DNA damage leading to the formation of thymidine dimmers, activates the neuroendocrine system leading to immunosuppression and release of neuroendocrine mediators, and causes increased synthesis and release of pro-inflammatory mediators from a variety of skin cells. The pro-inflammatory mediators increase the permeability of capillaries leading to infiltration and activation of neutrophils and other phagocytic cells into the skin. The net result of all these effects is inflammation and free radical generation (both reactive oxygen and nitrogen species). Furthermore, elastsases and other proteases (cathepsin G) released from neutrophils cause further inflammation, and activation of matrix metalloproteases. The inflammation further activates the transcription of various matrixes degrading metalloproteases, leading to abnormal matrix degradation and accumulation of non-functional matrix components. In addition, the inflammation and ROS cause oxidative damage to cellular proteins, lipids and carbohydrates, which accumulates in the dermal and epidermal compartments, contributing to the aetiology of photoaging. Strategies to prevent photodamage caused by this cascade of reactions initiated by UV include: prevention of UV penetration into skin by physical and chemical sunscreens, prevention/reduction of inflammation using anti-inflammatory compounds (e.g. cyclooxygenase inhibitors, inhibitors of cytokine generation); scavenging and quenching of ROS by antioxidants; inhibition of neutrophil elastase activity to prevent extracellular matrix damage and activation of matrix metalloproteases (MMPs), and inhibition of MMP expression (e.g. by retinoids) and activity (e.g. by natural and synthetic inhibitors).Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesSwain, Margaret C. ; Bulbrook, R. D. ; Hayward, J. L.
Oxford, UK : Blackwell Publishing Ltd
Published 1974Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The luteal phase plasma progesterone levels of 341 control patients were compared with those in 25 patients with early and 12 patients with advanced breast cancer. There was a significant increase of ovulatory failure and luteal deficiency in patients with advanced breast cancer.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesBULBROOK, R. D. ; MOORE, J. W. ; ALLEN, D. ; THOMAS, B. S. ; GRAVELLE, I. H. ; HAYWARD, J. L. ; WANG, D. Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesKern, S. ; Hayward, J. ; Roberts, S. ; Richardson, J. W. ; Rotella, F. J. ; Soderholm, L. ; Cort, B. ; Tinkle, M. ; West, M. ; Hoisington, D. ; Lander, G. H.
College Park, Md. : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: We have used neutron diffraction on polycrystalline samples of AnF4 (An=Th, U, and Np) to examine the structures. All are isostructural with monoclinic space group C2/c. The structure of UF4 has been examined in some detail as a function of temperature. The volume of the unit cell has a minimum not at lowest temperature (15 K) examined, but rather at ∼350 K. ThF4 also has a larger volume at low rather than room temperature; suggesting that this effect is caused by structural rather than electronic (as ThF4 has no 5f electrons) interactions. An examination of the coordination around the two independent An sites in UF4 shows that the fluorine configuration changes appreciably around An2 as a function of temperature. At low temperatures the distorted cubic antiprism structure is considerably more "puckered'' than at higher temperatures. This puckering requires more volume for the molecule, thus causing the volume to expand as the temperature is lowered. The temperature factors and the interatomic distances vary smoothly with temperature and show no unusual behavior. © 1994 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1467-8292Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: EconomicsType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1467-9248Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Political ScienceType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesHayward, J. A. ; Reimers, J. R.
College Park, Md. : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: A number of periodic lattices have historically been used to represent ice-1h in computer simulations. These vary in size, shape, and method of generation, and while they have served their intended purposes, their properties have rarely been documented in detail and their intercompatibility is unknown. We develop a method for generating sets of internally consistent lattices and apply it to determine eight unit cells containing from 96 to 768 water molecules in both near-cubic and slab arrangements. It can easily be applied to generate additional (larger) cells or representations of specific crystal faces. Each unit cell in this set has zero net dipole moment and minimal net quadrupole moment and is optimized using four different criteria to measure the randomness of the hydrogen bonding; if required, these criteria can easily be modified to suit the intended application and alternate sets thus generated. We find that Cota and Hoover's much used constraint for selecting unit cells with zero dipole moment is too restrictive, not permitting a fully random hydrogen-bonding network; also, unit-cell generation methods based on potential-energy minimization are found to prefer unrepresentative, highly ordered structures. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesMEEKER, R. B. ; GREENWOOD, R. S. ; HAYWARD, J. N.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyType of Medium: Electronic ResourceURL: