Search Results - (Author, Cooperation:J. Han)
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1Latest Papers from Table of Contents or Articles in PressRobert R. J Coebergh van den Braak; Anieta M. Sieuwerts; Zarina S. Lalmahomed; Marcel Smid; Saskia M. Wilting; Sandra I. Bril; Shanshan Xiang; Michelle van der Vlugt-Daane; Vanja de Weerd; Anne van Galen; Katharina Biermann; J. Han J. M van Krieken; Wigard P. Kloosterman; John A. Foekens; John W. M. Martens; Jan N. M. IJzermans
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-03-28Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2045-2322Topics: Natural Sciences in GeneralPublished by: -
2Latest Papers from Table of Contents or Articles in PressHe, J., Li, X., Zhuang, J., Han, J., Luo, G., Yang, F., Sun, Y., Liao, P., Han, Y., He, Y., Shi, H., Sun, E.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-12-11Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
3Articles: DFG German National LicensesGrünberg ; Sharon ; Hiltermann ; Brahim ; Dick ; Sterk ; Van Krieken, J. Han J. M.
Oxford BSL : Blackwell Science Ltd
Published 2000Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Rhinovirus infections in airway epithelial cells in vitro have been shown to upregulate intercellular adhesion molecule-1 (ICAM-1) expression. Epithelial ICAM-1, in its dual role as the major rhinovirus receptor and as adhesion molecule for inflammatory cells may be involved in the pathogenesis of rhinovirus-induced exacerbations of asthma.〈section xml:id="abs1-2"〉〈title type="main"〉ObjectiveWe aimed to investigate the effect of experimental rhinovirus 16 (RV16) infection on ICAM-1 expression in bronchial mucosal biopsies in asthma. In addition, the effect of 2 weeks pretreatment with inhaled budesonide (800 μg b.d.) on RV16-associated changes in ICAM-1 expression was studied.〈section xml:id="abs1-3"〉〈title type="main"〉MethodsThe study had a parallel, placebo-controlled design in 25 steroid-naive nonsmoking atopic asthmatic subjects. After 2 weeks budesonide (BUD) or placebo (PLAC) pretreatment bronchoscopy was performed 2 days before (day −2) and 6 days after (day 6) RV16 inoculation (on days 0 and 1). Immunohistochemical staining for ICAM-1 was performed on snap-frozen bronchial biopsies. ICAM-1 staining intensity on the basal epithelial cells was scored semiquantitatively from 1 (weak) to 3 (intense). Similarly, epithelial intactness was noted (1 = basal cells only, 2 = basal and parabasal cells, 3 = intact epithelium).〈section xml:id="abs1-4"〉〈title type="main"〉ResultsICAM-1 scores were not significantly different between the groups at day −2 (P ≥ 0.08). Subsequent RV16 infection was associated with a trend towards an increase in ICAM-1 expression in the BUD-group (P = 0.07), whereas the increase was significant in the PLAC-group (P = 0.03). However, the increase was not significantly different between the groups (P = 0.74). Epithelial intactness score was not different between the groups before RV16 infection (P ≥ 0.07), and no significant changes were observed in either group (P ≥ 0.59). Moreover, ICAM-1 score did not correlate significantly with epithelium score in either group, at any time-point (P ≥ 0.27).〈section xml:id="abs1-5"〉〈title type="main"〉ConclusionWe conclude that an RV16 common cold in atopic asthmatic subjects is associated with increased ICAM-1 expression in the bronchial epithelium, which is not related to epithelial intactness. Glucocorticoid treatment does not appear to prevent the RV16-associated increased ICAM-1 expression. This suggests that other treatment modalities are required to protect against the spreading of infection during rhinovirus-induced exacerbations in asthma.Type of Medium: Electronic ResourceURL: -
4Latest Papers from Table of Contents or Articles in PressHao Cheng, Hongwen Xuan, Christopher D. Green, Yixing Han, Na Sun, Hongjie Shen, Joseph McDermott, David A. Bennett, Fei Lan, Jing-Dong J. Han
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-07-18Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
5Latest Papers from Table of Contents or Articles in PressLin, Y.-W., Yu, H. H., Zhao, J., Han, M.-L., Zhu, Y., Akter, J., Wickremasinghe, H., Walpola, H., Wirth, V., Rao, G. G., Forrest, A., Velkov, T., Li, J.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-05-26Publisher: The American Society for Microbiology (ASM)Print ISSN: 0066-4804Electronic ISSN: 1098-6596Topics: BiologyMedicinePublished by: -
6Latest Papers from Table of Contents or Articles in PressXu, B., Tian, Z., Wang, J., Han, H., Lee, T., Mei, Y.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-07Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
7Latest Papers from Table of Contents or Articles in PressHuang, S., Ge, X., Yu, J., Han, Z., Yin, Z., Li, Y., Chen, F., Wang, H., Zhang, J., Lei, P.
The Federation of American Societies for Experimental Biology (FASEB)
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: The Federation of American Societies for Experimental Biology (FASEB)Print ISSN: 0892-6638Electronic ISSN: 1530-6860Topics: BiologyPublished by: -
8Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-09-27Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: materials science, nanotechnologyPublished by: -
9Latest Papers from Table of Contents or Articles in PressLi, X., Shepard, H. M., Cowell, J. A., Zhao, C., Osgood, R. J., Rosengren, S., Blouw, B., Garrovillo, S. A., Pagel, M. D., Whatcott, C. J., Han, H., Von Hoff, D. D., Taverna, D. M., La; Barre, M. J., Maneval, D. C., Thompson, C. B.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-10-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
10Latest Papers from Table of Contents or Articles in PressBian, Z., Zhang, J., Li, M., Feng, Y., Wang, X., Zhang, J., Yao, S., Jin, G., Du, J., Han, W., Yin, Y., Huang, S., Fei, B., Zou, J., Huang, Z.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-10-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
11Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-12-11Publisher: Genetics Society of America (GSA)Electronic ISSN: 2160-1836Topics: BiologyPublished by: -
12Latest Papers from Table of Contents or Articles in PressY. M. Lin ; A. Valdes-Garcia ; S. J. Han ; D. B. Farmer ; I. Meric ; Y. Sun ; Y. Wu ; C. Dimitrakopoulos ; A. Grill ; P. Avouris ; K. A. Jenkins
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-06-11Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
13Latest Papers from Table of Contents or Articles in PressJ. Han ; E. Li ; L. Chen ; Y. Zhang ; F. Wei ; J. Liu ; H. Deng ; Y. Wang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-07-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Binding, Competitive ; COP-Coated Vesicles/chemistry/metabolism ; Homeostasis ; Insulin Resistance ; *Lipid Metabolism ; Lipogenesis ; Liver/*metabolism ; Male ; Mice ; Mice, Obese ; Obesity/metabolism ; Phosphorylation ; Protein Processing, Post-Translational ; Protein Transport ; Signal Transduction ; Sterol Regulatory Element Binding Protein 1/*metabolism ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors/deficiency/genetics/*metabolism ; Vesicular Transport Proteins/metabolismPublished by: -
14Latest Papers from Table of Contents or Articles in PressY. Li ; J. Han ; Y. Zhang ; F. Cao ; Z. Liu ; S. Li ; J. Wu ; C. Hu ; Y. Wang ; J. Shuai ; J. Chen ; L. Cao ; D. Li ; P. Shi ; C. Tian ; J. Zhang ; Y. Dou ; G. Li ; Y. Chen ; M. Lei
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-02-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
15Latest Papers from Table of Contents or Articles in PressGabi W. van Pelt, Tessa P. Sandberg, Hans Morreau, Hans Gelderblom, J. Han J.M. van Krieken, Rob A.E.M. Tollenaar, Wilma E. Mesker
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-02-20Publisher: Wiley-BlackwellPrint ISSN: 0309-0167Electronic ISSN: 1365-2559Topics: MedicinePublished by: -
16Latest Papers from Table of Contents or Articles in PressGao, X., Yuan, Y.-Y., Lin, Q.-F., Xu, J.-C., Wang, W.-Q., Qiao, Y.-H., Kang, D.-Y., Bai, D., Xin, F., Huang, S.-S., Qiu, S.-W., Guan, L.-P., Su, Y., Wang, G.-J., Han, M.-Y., Jiang, Y., Liu, H.-K., Dai, P.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-04-28Publisher: BMJ Publishing GroupPrint ISSN: 0022-2593Electronic ISSN: 1468-6244Topics: MedicineKeywords: Open accessPublished by: -
17Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-05-03Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: mathematical physics, pattern recognitionPublished by: -
18Latest Papers from Table of Contents or Articles in PressAnderson, S. N., Zynda, G. J., Song, J., Han, Z., Vaughn, M. W., Li, Q., Springer, N. M.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-06-01Publisher: Genetics Society of America (GSA)Electronic ISSN: 2160-1836Topics: BiologyPublished by: -
19Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-05-10Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
20Latest Papers from Table of Contents or Articles in PressH. D. Xie, R. Z. Huang, X. J. Han, X. Yan, H. H. Zhao, Z. Y. Xie, H. J. Liao, and T. Xiang
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-02-08Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Electronic structure and strongly correlated systemsPublished by: