Search Results - (Author, Cooperation:J. Gerlach)
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1Latest Papers from Table of Contents or Articles in PressJ. Quick ; N. J. Loman ; S. Duraffour ; J. T. Simpson ; E. Severi ; L. Cowley ; J. A. Bore ; R. Koundouno ; G. Dudas ; A. Mikhail ; N. Ouedraogo ; B. Afrough ; A. Bah ; J. H. Baum ; B. Becker-Ziaja ; J. P. Boettcher ; M. Cabeza-Cabrerizo ; A. Camino-Sanchez ; L. L. Carter ; J. Doerrbecker ; T. Enkirch ; I. Garcia-Dorival ; N. Hetzelt ; J. Hinzmann ; T. Holm ; L. E. Kafetzopoulou ; M. Koropogui ; A. Kosgey ; E. Kuisma ; C. H. Logue ; A. Mazzarelli ; S. Meisel ; M. Mertens ; J. Michel ; D. Ngabo ; K. Nitzsche ; E. Pallasch ; L. V. Patrono ; J. Portmann ; J. G. Repits ; N. Y. Rickett ; A. Sachse ; K. Singethan ; I. Vitoriano ; R. L. Yemanaberhan ; E. G. Zekeng ; T. Racine ; A. Bello ; A. A. Sall ; O. Faye ; N. Magassouba ; C. V. Williams ; V. Amburgey ; L. Winona ; E. Davis ; J. Gerlach ; F. Washington ; V. Monteil ; M. Jourdain ; M. Bererd ; A. Camara ; H. Somlare ; M. Gerard ; G. Bado ; B. Baillet ; D. Delaune ; K. Y. Nebie ; A. Diarra ; Y. Savane ; R. B. Pallawo ; G. J. Gutierrez ; N. Milhano ; I. Roger ; C. J. Williams ; F. Yattara ; K. Lewandowski ; J. Taylor ; P. Rachwal ; D. J. Turner ; G. Pollakis ; J. A. Hiscox ; D. A. Matthews ; M. K. O'Shea ; A. M. Johnston ; D. Wilson ; E. Hutley ; E. Smit ; A. Di Caro ; R. Wolfel ; K. Stoecker ; E. Fleischmann ; M. Gabriel ; S. A. Weller ; L. Koivogui ; B. Diallo ; S. Keita ; A. Rambaut ; P. Formenty ; S. Gunther ; M. W. Carroll
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-02-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aircraft ; Disease Outbreaks/statistics & numerical data ; Ebolavirus/classification/*genetics/pathogenicity ; *Epidemiological Monitoring ; Genome, Viral/*genetics ; Guinea/epidemiology ; Hemorrhagic Fever, Ebola/*epidemiology/*virology ; Humans ; Mutagenesis/genetics ; Mutation Rate ; Sequence Analysis, DNA/*instrumentation/*methods ; Time FactorsPublished by: -
2Articles: DFG German National LicensesZeitler, M. ; Gerlach, J. W. ; Kraus, T. ; Rauschenbach, B.
Woodbury, NY : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The effect of the film thickness on the evolution of texture of polycrystalline titanium nitride films grown by photon and ion beam assisted deposition has been investigated. The layers were deposited in high-vacuum on (111)Si with the N-ion energy constant at 2 keV and the incident ion/titanium flux ratio constant at 0.66 ions/atom. X-ray pole figure measurements show that the biaxial {001} texture is changed to the biaxial {111} texture with an increase of the film thickness. The texture evolution is explained by the existence of open channeling directions and the minimization of the elastic deformation energy. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesGerlach, J. W. ; Preckwinkel, U. ; Wengenmair, H. ; Kraus, T. ; Rauschenbach, B.
Woodbury, NY : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The biaxial alignment of TiN on Si(111) films prepared by nitrogen ion beam assisted deposition at room temperature was studied. By reactive deposition within a nitrogen environment a preferred {111} orientation was obtained the growing TiN crystallites. In contrast, a nitrogen ion bombardment perpendicular to the surface of the substrate during deposition causes an {001} alignment of the crystallites. A 55° ion beam incidence produces both {111}-orientation relative to the surface and {100}-orientation relative to the ion beam. This results in a totally fixed orientation of the crystallites. Simultaneous UV-light illumination during ion bombardment promotes a uniformly oriented growth. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesRANK, G. H. ; GERLACH, J. H. ; ROBERTSON, A. J. ; VAN HOEVEN, R. P.
[s.l.] : Nature Publishing Group
Published 1978Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] We used the procedure described by Fuhrmann et al.2 for the isolation of plasma membrane vesicles capable of galactose transport. A 5,000g pellet from mechanically disrupted cells was resuspended at 1 mg protein ml"1 in ice cold osmotic stabiliser (400mMKCl, lmMMgCl2, 20 mM tri-ethanolamine). The ...Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0165-0327Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0022-3956Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1435-2451Source: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Zeitpunkt and Reihenfolge der diagnostischen und therapeutischen Maßnahmen sind zu planen. Ziele sind Lebenserhaltung, Vermeidung von Früh- und Spätkomplikationen und — schäden, möglichst weitgehende Wiederherstellung der Funktionen des Gehirns, der Sinnesorgane (Augen, Geruchsorgan), der Luft-und Speisewege (Nase, Nasenrachenraum und Nebenhöhlen, Kiefer, Z'ähne, Gaumen, Zunge) und gutes kosmetisches Behandlungsergebnis. Der Zeitplan soll bei Beginn der klinischen Behandlung nach Durchführung der Notmanßnahmen am Unfallort aufgestellt werden. Sofort., Früh-und Spätmaßnahmen sind zu unterscheiden. Nach Durchführung der Sofortmaßnahmen wird über die Reihenfolge der Versorgung durch die verschiedenen Fachäzte entschieden und ihre Tätigkeit koordiniert. Jeder einzelne stellt für sein Fachgebiet einen Zeitplan der Maß nahmen auf, alle zusammen einen Gesamtzeitplan. Danmn wird auch entschieden, ob, wann und in welcher Weise eine operative Zusammenarbeit stafffindet. Sie kommt vor allem zwischen Neurochirurgen, Oto-Rhinologen und - seltener- Ophthalmologen in Betracht. Der Zeitplan muß in Anpassung an den Verlauf beweglich bleiben. Mehrfachverletzungen erfordern Einschaltung anderer Fachärzte.[/ab]Notes: Summary Time and sequence of diagnostic and therapeutic actions have to be planned carefull. The purpose is to conserve life, to prevent early and late complications as well as damages, to restore as far as possible functions of brain and sensory organs (eyes, olfactory organ), of breathing and food-passages (nose epipharynx, paranasal sinus, maxillae, teeth, palate, tongue) and, finally, to aim at a good cosmetic result. The plan should be formed at the beginning of clinical treatment, that is after first aid treatment at the place of the accident is already accomplished. Immediate means have to be distinguished form early and late ones. After the immediate actions have been taken, the questions, in what sequence the different specialists should start their treatment, has to be judged and settled. Actions of different specialists have to be coordinated. Each one has form a plan concerning his special field, all of them together should get to a common plan. At this point the decision has to be made wether there should be surgical team-work, and if so, when and how. This could particularly concern neurosurgeons, otorhinologists and, more rarely ophthalmologists. The plan has to be flexible, so that it may be adapted to change according to the course of the disease. In cases of multiple injuries, other consulting specialists are needed in addition.[/ab]Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1434-4726Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1432-1912Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1432-1904Source: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesGuleke, N. ; Felix, W. ; Zehrer, G. ; Schönbauer, L. ; Gerlach, J. ; Otto, E. ; Kroll, J. -W. ; Zülch, K. J. ; Kautzky, R. ; Röttgen, P. ; Sunder-Plaßmann, P. ; Schaltenbrandt, G. ; Klar, E. ; Bronisch, F. W. ; Loew, F.
Springer
Published 1950Staff ViewISSN: 1432-1459Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1432-1459Keywords: Temperature measurement ; Skin temperature ; Trigeminal neuralgiaSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Comparative measurements of cutaneous temperature were recorded with a contact-resistance thermometer and an infrared-ray measuring device. The test material consisted of 310 healthy volunteers and 37 patients, 16 with trigeminal neuralgia and 21 with L5 syndrome. The temperature curve usually proved to be symmetrical; at a few points the results are dependent on the method of measurement and can be explained by the different principles involved. The normal temperature curve showed the familiar dependence on environmental conditions; in the two small series of patients, raised cutaneous temperature was seen in the affected area in the group with trigeminal neuralgia, while the temperature was lower than normal in the affected area in patients with L5 syndrome. These results indicate local functional impairments of the antonomic nervous system in both these conditions.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0165-1781Keywords: parkinsonism ; tardive dyskinesia ; γ-Vinyl GABASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesBjørndal, N. ; Bjerre, M. ; Gerlach, J. ; Kristjansen, P. ; Magelund, G. ; Oestrich, I. H. ; Wæhrens, J.
Springer
Published 1980Staff ViewISSN: 1432-2072Keywords: Schizophrenia ; Haloperidol ; High dosage treatment ; ProlactinSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract In a 12-weeks double-blind study high dosage versus standard dosage haloperidol therapy was evaluated in 23 male, chronic schizophrenic inpatients. The patients were relatively treatment-resistant and, in spite of traditional neuroleptic medication, were characterized by a moderate to severe degree of illness. At the end of the trial the dose of haloperidol in the standard dosage group was 12–36 mg/day (mean 15), in the high dosage group 10–240 mg/day (mean 103). No significant difference in therapeutic effect was found between the two groups as measured by the Brief Psychiatric Rating Scale and global assessment. About half the patients in both groups improved during the trial. A greater incidence of side effects was noticed in the high dosage group than in the standard group, especially in the form of sedation (5 of 12 patients), aggressive episodes (three patients), muscular weakness and tendency to fall (two patients), and epileptic attacks (one patient). The incidence of extrapyramidal phenomena showed fewer differences between the two groups. In addition, the high dosage group showed a temporary rise in serum alkaline phosphatase and serum aspartate-aminotransferase. There was a positive correlation between the dose of haloperidol and serum haloperidol, and between the haloperidol dose of up to 80 mg/day and serum prolactin. At higher doses prolactin response leveled off. Neither serum haloperidol nor serum prolactin showed any correlation to clinical response. It is concluded (1) that very high doses of haloperidol in only a few cases show any therapeutic advantage over haloperidol in standard doses; (2) that high dosage treatment has a higher incidence of side effects; and (3) that the serum concentrations of a given neuroleptic and of prolactin are of very limited value in the monitoring of neuroleptic treatment.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesKorsgaard, S. ; Casey, D. E. ; Damgaard Pedersen, N. E. ; Jørgensen, A. ; Gerlach, J.
Springer
Published 1981Staff ViewISSN: 1432-2072Keywords: Anergic schizophrenia ; Vasopressin ; Lysine-8-vasopressin ; Video technique for blind evaluationSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Sixteen out of 19 patients suffering from chronic anergic schizophrenia completed a placebo-controlled crossover study with lysine-8-vasopressin (LVP), following a schedule of 1 week of placebo, 3 weeks of LVP, starting with 22.5 IU/day, gradually increased to 67.5 IU/day, and finally 4 weeks of placebo. The psychia state was evaluated with the Brief Psychiatric Rating Scale (BPRS), during weekly live interviews, and following videotaped BPRS interviews at the beginning and end of the LVP period, and at the end of the final placebo period. Symptoms of parkinsonism and tardive dyskinesia were also videotaped during a standardized examination at the same intervals. The videotapes were subsequently randomized and evaluated blindly. The results of the live interviews showed a significant (P〈0.05) decrease in the BPRS anergic factor after 2 and 3 weeks of LVP treatment, but there were no changes in any single item, other BPRS factors, or the BPRS total score. The results of the videotape evaluations showed that the BPRS thinking disorder factor was significantly (P〈0.05) decreased after 3 weeks of LVP, whereas the total BPRS score was unchanged. No consistent changes in parkinsonism or tardive dyskinesia were found. Although side effects were few, six patients became agitated or aggressive during the LVP treatment. The beneficial effect on thought disorder and anergia, but the absence of global effects on the schizophrenic syndrome, illustrates the need for further research with other vasopressin analogues. The advantages and disadvantages of live and videotaped psychiatric interviews are also discussed.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1432-2072Keywords: Tardive dyskinesia ; Parkinsonism ; Haloperidol ; Thioridazine ; Clozapine ; BiperidenSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract In a cross-over trial 16 elderly psychiatric patients with tardive dyskinesia were treated with thioridazine (median dose, 267.5 mg/day) for three months, followed by haloperidol (5.25 mg/day), haloperidol (5.25 mg/day) + biperiden (6 mg/day), thioridazine (267.5 mg/day), and clozapine (62.5 mg/day, only 7 patients), all for periods of 4 weeks with 4-week drug-free intervals. The tardive dyskinesia syndrome and the parkinsonism were evaluated blind according to a self-constructed rating scale and a modified Webster scale from weekly video-tape recordings. At the end of the treatment periods the hyperkinesia score was lower during haloperidol than during either thioridazine for 3 months (total score, 2.2 vs. 3.2, P〈0.05), thioridazine for 4 weeks (total score, 2.2 vs. 4.8, P〈0.02), or haloperidol + biperiden (score, 2.2 vs. 6.2, P〈0.01). Clozapine had no significant antihyperkinetic effect, but in one patient it exerted a clear antiparkinsonian effect. After withdrawal of the initial thioridazine treatment, the hyperkinesia score was lower than after the subsequent haloperidol treatment (6.5 vs. 9.0, P〈0.01), but after the second thioridazine period the hyperkinesia was of the same magnitude as after the preceding haloperidol periods. Biperiden increased the tardive dyskinesia syndrome during treatment, but did not significantly influence the syndrome after withdrawal of the treatment. It is concluded that (1) haloperidol (a strong antidopaminergic neuroleptic) has a more pronounced antihyperkinetic effect than thioridazine and clozapine (weaker antidopaminergic neuroleptics); (2) haloperidol might have a greater tendency to induce tardive dyskinesia than thioridazine; (3) administration of anticholinergics concomitant with neuroleptic drugs antagonizes the antihyperkinetic effect of haloperidol, but may not influence the intensity of tardive dyskinesia after withdrawal of the treatment.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1432-2072Keywords: Tardive dyskinesia ; Parkinsonism ; Cholinomimetics ; RS 86Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract RS 86, a specific muscarinic agonist, was evaluated in a blind, placebo-controlled, single-dose trial in 10 psychiatric patients with stable tardive dyskinesia (TD). RS 86, 0.5–4 mg orally, produced no significant effects in TD, although 4 mg caused a minimal aggravation in parkinsonism. Side effects of the highest dose (4 mg) included hypersalivation (eight patients), nausea (6), sweating (3), and vomiting (3). It is concluded that treatmetn with RS 86 and probably other cholinomimetics has no or only limited beneficial effect in TD.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0942-0940Source: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Summary During 34 neurosurgical procedures the temperatures of the dura and of the cerebral cortex were measured by means of infra-red thermometry; their behaviour in relationship to time after washing with physiological saline was observed. Under the given experimental conditions the cerebral cortex showed a mean initial temperature of 33.6° C, and the mean time required for the temperature to return to this initial level amounted to about 2 1/2 minutes. In order to maintain normal temperatures in the depths of the cerebral tissue during brain operations, washings with appropriate solutions are necessary with the best durations of irrigation.Abstract: Résumé Au cours de 34 procédés neuro-chirurgicaux, la température de la duremère et du cortex cérébral fut mesurée par les moyens de la thermométrie infra-rouge; leur comportement selon le temps écoulé après lavage au sérum salé physiologique fut observé. Sous des conditions expérimentales données, le cortex cérébral montrait une température initiale moyenne de 33,6° C, et le temps moyen nécessaire à la température pour retourner à ce taux initial se situait aux environs de 2 minutes et demi. Afin de maintenir une température normale dans les profondeurs du tissu cérébral durant les interventions cérébrales, des lavages avec des solutions appropriées sont nécessaires dans les meilleures conditions d'irrigation.Notes: Zusammenfassung Während 34 neurochirurgischer Eingriffe wurde die Temperatur von Dura- und Hirnoberfläche mittels Infrarot-Thermometrie und ihr Verhalten in Zeitabhängigkeit nach Spülung mit physiologischer Kochsalzlösung bestimmt. Unter den gegebenen Versuchsbedingungen zeigte die Hirnrinde einen Ausgangsmittelwert von 33,6° C, die durchschnittliche Rückgangszeit zur Ausgangstemperatur betrug etwa 2 1/2 Minuten. Zur Aufrechterhaltung der normalen Kerntemperatur des Hirngewebes bei Hirnoperationen sind Spülungen mit geeigneten Lösungen, am besten Dauerberieselungen, erforderlich.Type of Medium: Electronic ResourceURL: