Search Results - (Author, Cooperation:J. F. Davidson)
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1Latest Papers from Table of Contents or Articles in PressJ. M. Rothberg ; W. Hinz ; T. M. Rearick ; J. Schultz ; W. Mileski ; M. Davey ; J. H. Leamon ; K. Johnson ; M. J. Milgrew ; M. Edwards ; J. Hoon ; J. F. Simons ; D. Marran ; J. W. Myers ; J. F. Davidson ; A. Branting ; J. R. Nobile ; B. P. Puc ; D. Light ; T. A. Clark ; M. Huber ; J. T. Branciforte ; I. B. Stoner ; S. E. Cawley ; M. Lyons ; Y. Fu ; N. Homer ; M. Sedova ; X. Miao ; B. Reed ; J. Sabina ; E. Feierstein ; M. Schorn ; M. Alanjary ; E. Dimalanta ; D. Dressman ; R. Kasinskas ; T. Sokolsky ; J. A. Fidanza ; E. Namsaraev ; K. J. McKernan ; A. Williams ; G. T. Roth ; J. Bustillo
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Escherichia coli/genetics ; Genome, Bacterial/*genetics ; Genome, Human/*genetics ; Genomics/*instrumentation/*methods ; Humans ; Light ; Male ; Rhodopseudomonas/genetics ; *Semiconductors ; Sequence Analysis, DNA/*instrumentation/*methods ; Vibrio/geneticsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Multiple plasma cell tumours of the skin may, on rare occasions, precede clinical, radiological and laboratory evidence of systemic myelomatosis. A man presented with several plasma cell tumours of the skin but with no detectable evidence of the disseminated myelomatosis to which he succumbed 16 months later. Multiple cutaneous extra-medullary plasmacytomas should be regarded as a cutaneous expression of multiple myelomatosis.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0026-7074Topics: Classical StudiesURL: -
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ISSN: 0026-7074Topics: Classical StudiesNotes: MiscellaneaURL: -
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ISSN: 0026-7074Topics: Classical StudiesNotes: MiscellaneaURL: -
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ISSN: 0026-7074Topics: Classical StudiesURL: -
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ISSN: 0026-7074Topics: Classical StudiesNotes: MiscellaneaURL: -
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ISSN: 0026-7074Topics: Classical StudiesURL: -
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ISSN: 0026-7074Topics: Classical StudiesNotes: MiscellaneaURL: -
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ISSN: 0026-7074Topics: Classical StudiesNotes: MiscellaneaURL: -
11Articles: DFG German National LicensesChristopher, L. J. ; Crooks, J. ; Davidson, J. F. ; Erskine, Z. G. ; Gallon, S. C. ; Moir, D. C. ; Weir, R. D. ; Hunter, K. R.
Springer
Published 1977Staff ViewISSN: 1432-1041Keywords: Rauwolfia derivatives ; breast cancer ; multicentre studySource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMedicineNotes: Summary Studies reporting a suspected association between breast cancer and rauwolfia derivatives were first published in 1974 and more recent studies have produced conflicting results. A further study is described in which groups of investigators from Aberdeen, Dundee and London attempted to ascertain the previous exposure to rauwolfia derivatives of female patients discharged from hospital with a confirmed diagnosis of breast cancer. Their exposure as recorded in the hospital and general practitioners' records was compared with that in two control groups, matched by general practitioner, age, year of admission to hospital and marital state, the first comprising patients with a cancer other than breast cancer and the second, patients with a non-malignant disorder. For patients with breast cancer compared with those with a non-malignant disorder the overall estimate of the relative risk of breast cancer in patients exposed to rauwolfia derivatives is 0.94 (95 patients exposed). The occurrence of hypertension and use of hypotensive agents and prolactin stimulators was also noted. Possible sources of bias were examined and none appeared to be significant. The problems created by the multicentre approach are also discussed.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1432-1041Keywords: Drug therapy ; adverse effectsSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMedicineNotes: Summary Existing methods of detecting adverse drug reactions are reviewed and an information system whereby the total number of patients exposed to a drug and the total number of patients developing an adverse reaction can be ascertained is described. Its potential as a monitoring system was tested by investigating, in 204 patients identified as receiving α-methyldopa, the known association of haemolytic anaemia with that drug. — Patients remaining on α-methyldopa were repeatedly screened and in this series one patient had developed haemolytic anaemia and 10 patients had antibodies to α-methyldopa as evidenced by a positive direct antiglobulin test. Follow-up effectively determined the frequency of haemolytic anaemia which appeared to be a relatively small hazard and should not prejudice the use of the drug. This study has highlighted the difficulties in the adequate assessment of hypertension prior to commencing treatment and has shown that drug monitoring for adverse reactions may have an important role in the establishment of criteria for the more effective use of drugs.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1435-1528Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyPhysicsNotes: Summary Results are given for the flow of particles, and of the associated air, through orifice plates and shaped nozzles in the side of an air fluidised bed. These data, and other data published by previous workers, indicate that the solids flow can be predicted by treating the fluidised solids as an inviscid liquid and applyingBernoulli's theorem. This leads to a simple result, accurate enough for design purposesM=π r e 2 C D ϱ0 (2g H 0)1/2. For the orifice plates the discharge coefficientC D is about 0.5; for the shaped nozzles the discharge coefficient approaches unity for longer nozzles. Although these results indicate behaviour closely analogous to that of a liquid, detailed study of jet trajectories indicates a velocity coefficient of somewhat less than unity (of order 0.5–0.7) for orifice plates, associated with a contraction coefficient of about unity. The differences from liquid behaviour of the particle jet may be due to the associated air flow which has two components: 1. Air is entrained in the voids between the outgoing particles, the voidage fraction in the jet being somewhat greater than the voidage at incipient fluidisation. 2. Additional air percolates through the interstices, and its flow can be predicted approximately fromDarcy's law. The total efflux of air with the particle jet is markedly reduced by lengthening the shaped nozzles, because component [2] is reduced on account of the greater path length for percolating air.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0001-1541Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Experiments in which a liquid film runs over a vertical string of spheres surrounded by a concentric tube through which air is blown upward have shown that loading in a packed tower is due to the formation of standing waves on the liquid film. In the ball-and-tube system a wave is formed just below the equator of each ball, owing to the pressure gradient within the air stream as it accelerates through the narrowing gap between the ball and the tube. Interfacial shear and surface tension are of secondary importance. The similarity between the characteristics of the ball-and-tube system and those of the randomly packed tower suggests that loading in the latter system is also due to wave formation. With this concept of loading, a correlation has been dérived.Additional Material: 10 Ill.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0001-1541Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Kerosine or propane was injected near the base of a small, air-fluidized bed of sand at 940°C. The fraction of fuel burnt within the bed was determined from a heat balance, for various particle sizes, fluidizing velocities, and bed depths.Assuming the initial formation of a train of fuel vapor bubbles, theoretical analysis indicated two stages of combustion: (1) rapid consumption of the oxygen initially between fuel vapor bubbles; (2) slow consumption of oxygen initially outside the fuel vapor region by radial diffusion of oxygen and fuel vapor, analogous to a diffusion flame.Comparison of experiment with theory gave effective radial diffusion coefficients of the same order of magnitude as the molecular diffusion coefficient. It was inferred that combustion occurs largely by a diffusion flame within the bed, with diffusion through the particulate phase being the rate-controlling step. This explains why fuel distribution is so important in attaining efficient combustion.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0001-1541Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: This paper reviews the literature about fluidized combustion of char and volatiles from coal. While the rate of combustion of particles bigger than about 2 mm is mainly limited by the rate of diffusion of oxygen, there is usually an effect of chemical rate. As particle diameter decreases, the influence of chemical rate increases. Char particles are porous and combustion occurs in pores near their exterior. Char reactivity can be modelled by an effective pore area for combustion.At high bed temperatures (〉1,150 K), the rate of combustion of volatiles is limited by the rate of mixing of fuel and oxygen. At low bed temperatures (〈1,000 K), combustion reactions are inhibited by the inert particles in the bed.Type of Medium: Electronic ResourceURL: