Search Results - (Author, Cooperation:J. Edelmann)

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  1. 1
    Staff View
    Publication Date:
    2015-10-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cell Transformation, Neoplastic/genetics ; Clone Cells/metabolism/pathology ; DNA Copy Number Variations/genetics ; *Disease Progression ; *Evolution, Molecular ; Exome/genetics ; Genes, myc/genetics ; Humans ; Ikaros Transcription Factor/genetics ; Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis/*genetics/pathology/therapy ; MAP Kinase Signaling System/genetics ; Mutation/*genetics ; Neoplasm Recurrence, Local/*genetics ; Prognosis ; RNA Processing, Post-Transcriptional/genetics ; RNA Transport/genetics ; Ribosomal Proteins/genetics ; Treatment Outcome
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Gorbunov, A. A. ; Wolf, B. ; Edelmann, J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1089-7623
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Electrical Engineering, Measurement and Control Technology
    Notes:
    We propose to use silver tips for scanning tunneling microscopy (STM). Silver is the cheapest noble metal that is practically chemically inactive in the air environment. A simple reliable procedure of the tip preparation and resharpening is presented. The procedure is based on two-step electrochemical processing resulting in final tip curvature of less than 200 nm in radius as seen by an electron microscope. The tips show durability for at least a week of daily operation in an air STM.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Lessig, R. ; Edelmann, J.
    Springer
    Published 1998
    Staff View
    ISSN:
    1437-1596
    Keywords:
    Key words Short tandem repeat ; Y-chromosome ; Y-haplotype analysis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Notes:
    Abstract In order to apply a set of useful and high polymorphic Y-STRs in paternity testing, we performed a population genetic study from Saxony. The allele distributions of the systems DYS19, DYS385, DYS389I/II and DYS390 were investigated in a sample of 250 unrelated males from the area of Leipzig. PCR products were detected using native polyacrylamide gel electrophoresis as well as capillary electrophoresis and GenScan Software on the ABI Prism 310 DNA sequencer. Haplotype frequency data of 164 different types were obtained which show that these four systems are very useful for special cases of paternity and forensic stain analysis. In addition several confirmed father-son pairs were examined using the paternity cases of the institute. One mutation was found in the system DYS390 and sequencing data are presented.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Sonntag, J. ; Voigtmann, R. ; Edelmann, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1437-1596
    Keywords:
    GEDNAP IV ; GEDNAP V ; RFLP systems PCR systems ; Bloodstains
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Notes:
    Abstract In the collaborative exercise GEDNAP IV one EDTA blood sample (2 ml) and 5 bloodstains (0.5 ml on cotton) were investigated and in GEDNAP V, a total of 8 bloodstains (0.5 m1 on cotton), including 2 mixed bloodstains. DNA typing was carried out using the RFLP systems YNH24/Hinf I and MS43a/Hinf I and the PCR systems HLA DQα, D1S80, ApoB and YNZ22. In both exercises approximately 20 laboratories obtained results using the RFLP systems. Of the PCR systems, DIS80 was the most commonly used (14 labs in GEDNAP IV; 18 labs in GEDNAP V). The interlaboratory standard deviation for YNH24 in both exercises was approx. 0.6%, for MS43a 0.7–2.2% (GEDNAP IV) and 0.4–1.4% (GEDNAP V), depending on the fragment size. The fragment size calculation performed in each laboratory yielded a standard deviation twice that obtained when the fragment size calculation was performed centrally (IfR, Münster). In GEDNAP III, a system-specific corridor was developed to define the limits of deviation; this was modified for the present study by combining the fragment size ranges of YNH24 and MS43a. In both studies a subgroup of laboratories was involved in preliminary exercises using three PCR VNTRs and the system HLA DQα. Owing to the substantial variation in experience of the participating laboratories with PCR typing the results obtained in these two studies do not fulfil the basic quality criteria of the GEDNAP studies.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses