Search Results - (Author, Cooperation:J. Dunn)
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1Latest Papers from Table of Contents or Articles in PressNathanael D. Sallada, Kerri J. Dunn and Bryan W. Berger
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-01-10Publisher: American Chemical Society (ACS)Print ISSN: 0006-2960Electronic ISSN: 1520-4995Topics: BiologyChemistry and PharmacologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressNan, K., Kang, S. D., Li, K., Yu, K. J., Zhu, F., Wang, J., Dunn, A. C., Zhou, C., Xie, Z., Agne, M. T., Wang, H., Luan, H., Zhang, Y., Huang, Y., Snyder, G. J., Rogers, J. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-03Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
3Latest Papers from Table of Contents or Articles in PressN. Annaluru ; H. Muller ; L. A. Mitchell ; S. Ramalingam ; G. Stracquadanio ; S. M. Richardson ; J. S. Dymond ; Z. Kuang ; L. Z. Scheifele ; E. M. Cooper ; Y. Cai ; K. Zeller ; N. Agmon ; J. S. Han ; M. Hadjithomas ; J. Tullman ; K. Caravelli ; K. Cirelli ; Z. Guo ; V. London ; A. Yeluru ; S. Murugan ; K. Kandavelou ; N. Agier ; G. Fischer ; K. Yang ; J. A. Martin ; M. Bilgel ; P. Bohutski ; K. M. Boulier ; B. J. Capaldo ; J. Chang ; K. Charoen ; W. J. Choi ; P. Deng ; J. E. DiCarlo ; J. Doong ; J. Dunn ; J. I. Feinberg ; C. Fernandez ; C. E. Floria ; D. Gladowski ; P. Hadidi ; I. Ishizuka ; J. Jabbari ; C. Y. Lau ; P. A. Lee ; S. Li ; D. Lin ; M. E. Linder ; J. Ling ; J. Liu ; M. London ; H. Ma ; J. Mao ; J. E. McDade ; A. McMillan ; A. M. Moore ; W. C. Oh ; Y. Ouyang ; R. Patel ; M. Paul ; L. C. Paulsen ; J. Qiu ; A. Rhee ; M. G. Rubashkin ; I. Y. Soh ; N. E. Sotuyo ; V. Srinivas ; A. Suarez ; A. Wong ; R. Wong ; W. R. Xie ; Y. Xu ; A. T. Yu ; R. Koszul ; J. S. Bader ; J. D. Boeke ; S. Chandrasegaran
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; *Chromosomes, Fungal/genetics/metabolism ; DNA, Fungal/genetics ; Genes, Fungal ; Genetic Fitness ; Genome, Fungal ; Genomic Instability ; Introns ; Molecular Sequence Data ; Mutation ; Polymerase Chain Reaction ; RNA, Fungal/genetics ; RNA, Transfer/genetics ; Saccharomyces cerevisiae/cytology/*genetics/physiology ; Sequence Analysis, DNA ; Sequence Deletion ; Synthetic Biology/*methods ; Transformation, GeneticPublished by: -
4Latest Papers from Table of Contents or Articles in PressWoroniecka, K., Chongsathidkiet, P., Rhodin, K., Kemeny, H., Dechant, C., Farber, S. H., Elsamadicy, A. A., Cui, X., Koyama, S., Jackson, C., Hansen, L. J., Johanns, T. M., Sanchez-Perez, L., Chandramohan, V., Yu, Y.-R. A., Bigner, D. D., Giles, A., Healy, P., Dranoff, G., Weinhold, K. J., Dunn, G. P., Fecci, P. E.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-09-05Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
5Latest Papers from Table of Contents or Articles in PressS. J. Dunn ; G. Martello ; B. Yordanov ; S. Emmott ; A. G. Smith
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-06-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Culture Techniques ; Computational Biology ; Embryonic Stem Cells/*metabolism ; *Gene Expression Regulation ; *Gene Regulatory Networks ; Mice ; Pluripotent Stem Cells/*metabolism ; Transcription Factors/genetics/*metabolismPublished by: -
6Latest Papers from Table of Contents or Articles in PressN. Rohringer ; D. Ryan ; R. A. London ; M. Purvis ; F. Albert ; J. Dunn ; J. D. Bozek ; C. Bostedt ; A. Graf ; R. Hill ; S. P. Hau-Riege ; J. J. Rocca
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-01-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
7Articles: DFG German National LicensesStaff View
ISSN: 0173-0835Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyChemistry and PharmacologyAdditional Material: 11 Ill.Type of Medium: Electronic ResourceURL: -
8Latest Papers from Table of Contents or Articles in PressChambers, S. K., Hyde, M. K., Laurie, K., Legg, M., Frydenberg, M., Davis, I. D., Lowe, A., Dunn, J.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-02-18Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, OncologyPublished by: -
9Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-05-10Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: behaviour, developmental biology, ecologyPublished by: -
10Articles: DFG German National LicensesLa Fontaine, B. ; Baldis, H. A. ; Villeneuve, D. M. ; Dunn, J. ; Enright, G. D. ; Kieffer, J. C. ; Pépin, H. ; Rosen, M. D. ; Matthews, D. L. ; Maxon, S.
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Space–time-resolved Thomson scattering was used to characterize the electron and ion temperatures in laser produced plasmas of various atomic numbers (Z=6, 13, 32, 73, 92). A Nd:glass laser with intensity between 1013 and 5×1014 W/cm2 was used to produce plasmas of relevance to laser fusion and x-ray laser studies. A comparison of the electron temperature and density deduced from Thomson scattering, x-ray spectroscopy, and lasnex hydrocode simulations is presented.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesBarnsley, R. ; Abbey, A. ; Dunn, J. ; Lea, S. ; Peacock, N. J.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: This spectrometer was designed to give access to a wide range of Bragg angles and crystal focal lengths while using the Rowland circle radius as a free parameter. Stability is achieved using a rigid beam or "Rowland chord,'' which provides a reference axis for all the critical alignments, the chord length being variable between about 0.2 and 5 m. Crystals of size up to 100×30×0.5 mm can be accommodated in a novel four-pillar jig, (λ/δλ) is typically 104 in the wavelength range from 0.1 to 1.3 nm, depending on the crystal. Various detectors have been used, including photographic film, multiwire gas proportional counters and large area CCD detectors, the latter having a 2-D spatial resolution of 22.5 μm (1152×1242 pixels, 26×28 mm2), a quantum efficiency greater than 20% between 0.7 and 12 keV and an energy resolution of about 150 eV. By sacrificing energy resolution, a one-dimensional mode with on-chip binning allows ∼ms time resolution of spectra from high flux sources such as tokamaks and synchrotrons. Results presented include photographic spectra from tokamak, beam foil and laser produced sources, and CCD spectra from tokamak and standard electron-beam excitation laboratory sources.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesFinn, C.B. ; Dunn, J. ; Buxton, E.J. ; Luesley, D.M. ; Shafi, M.
238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
Published 1993Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A retrospective review of 373 patients with stage I invasive epithelial ovarian cancer was undertaken over a 5 year period to develop a model to characterize the patient at high risk. Actuarial 5-year survival was 70%. To identify factors with an independent effect on 5-year survival, a logistic regression analysis was performed. Adjuvant chemotherapy, histologic grade and peritoneal washings, were identified as independent variables. A model to determine the predictivity of survival was created using a learning sample (2/3 of the cases) and the model was then used to reclassify a validation sample (1/3 of the cases). Using all the independent variables, outcome was predicted correctly in 78% of cases. However the model failed to improve identification of those at risk of recurrence (specificity of 53%).Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesVan Geene, P. ; Varma, R. ; Dunn, J. ; Chan, K.K. ; Luesle, D.M.
Suite 500, 5th Floor, 238 Main Street, Cambridge Massachusetts 02142, USA : Blackwell Science Inc.
Published 1996Staff ViewISSN: 1525-1438Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Maximal cytoreductive surgery in advanced epithelial ovarian carcinoma (EOC) has become commonplace in management despite the inability of prospective trials to demonstrate a convincing improvement in long-term survival. Optimal cytoreduction is only possible in 23–77% of cases, perhaps due to differences in tumor biology. In a retrospective analysis of 219 women, we have investigated one possible variable in tumor biology, namely the pattern of intraperitoneal spread. Median survival in the study group was 15.2 months (CI: 13.2–17.3). One hundred women had predominantly localized bulky spread and 119 had seedling spread to the peritoneum. The number of optimally debulked patients in the two groups was not significantly different (P = 0.9). Fifteen patients with bulky disease, had complete macroscopic clearance. Residual disease and performance status were highly significant prognostic factors. On univariate analysis, patients with seedling spread had a significantly poorer prognosis. Multivariate analysis showed that if for like cases: stage, residual disease, performance status, age, histology and differentiation were compared, the tumors with bulky spread carried a better prognosis than those with seedling spread. It has been demonstrated in this analysis that the pattern of spread is an independent prognostic factor of clinical significance.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesShafi, M. I. ; Dunn, J. A. ; Chenoy, R. ; Buxton, E. J. ; Williams, C. ; Luesley, D. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objective To investigate the use of a digital imaging system for colposcopy, its use for image analysis and quantification of the colposcopic features that may predict histological outcome as defined by large loop excision of transformation zone.Design Prospective programme study of all patients undergoing colposcopy for cytological abnormalities.Setting Dudley Road Hospital, Birmingham.Subject Fifty consecutive patients having cytological and colposcopic abnormality treated with large loop excision of transformation zone formed the study group.Main outcome measures Pretreatment and colposcopic features correlated with histological diagnosis of excised transformation zone.Results Index cytology and current smoking status are the most important variables for prediction of histological diagnosis. Other important variables are focality of lesion, surface pattern, intercapillary distance and degree of acetowhiteness.Conclusion Digital imaging colposcopy allows image capture, processing and objective analysis. This methodology holds advantages for basic and clinical research, teaching, diagnostics and clinical audit. The system can act as a quality control tool for colposcopy units. This system should prove invaluable for further quantitative studies, for natural history studies and for those patients with deferred treatment of their cytological and colposcopic abnormalities. The statistical models described may be incorporated into the system and can aid the colposcopist in management of the woman with abnormal cervical cytology and colposcopic abnormality.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesShafi, M. I. ; Dunn, J. A. ; Buxton, E. J. ; Finn, C. B. ; Jordan, J. A. ; Luesley, D. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objectives To determine factors that may predict cytological outcome at 6 months following large loop excision of transformation zone (LLETZ) for cervical intra epithelial neoplasia (CIN) and to investigate the outcome in women with continuing cytological abnormality.Design Case controlled retrospective study.Setting Dudley Road Hospital, Birmingham and Midland Hospital for Women.Subjects Fifty-eight women with abnormal follow up cytology and a control group of 116 women.Main outcome measures The relation between pretreatment and treatment factors and cytological outcome, and the relation between cytology and histology in women who had biopsies for persistent adnormal cytology.Results Univariate and stepwise logistic regression analysis showed that the number of sectors of atypical transformation zone (lesion size) and the excision margin status of the large loop excision specimen are of prognostic importance for the prediction of cytological abnormality at the 6 month follow up visit. Sixteen women have undergone further cervical biopsy. Of the five cases of persistent CIN, four had cytological changes showing moderate or severe dyskaryosis. Of the 11 women with koilocytosis or normal histology, 10 had mild dyskaryosis or borderline changes on their follow up cytology.Conclusion Lesion size and excision margin status are important correlates of follow up cytology when treating patients for CIN with LLETZ. All women with abnormal cervical cytology at follow up should undergo colposcopic assessment. Excision biopsy is indicated if follow up cytology shows moderate or severe dyskaryosis, especially if still present 12 months after treatment.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesFINN, CATHERINE B. ; LUESLEY, D. M. ; BUXTON, E. J. ; BLACKLEDGE, G. R. ; KELLY, K. ; DUNN, J. A. ; WILSON, S.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objective To review the incidence of Stage I epithelial ovarian carcinoma in the West Midlands region and to identify prognostic factors that have a significant effect on survival.Design A retrospective review of all Stage I ovarian cancer patients registered from 1.1.80 to 31.12.84.Setting West Midlands Regional Cancer Registry.Population 457 patients with Stage I ovarian cancer—373 with epithelial ovarian carcinoma.Main outcome measures Survival at censor date of 30.6.89.Results 28% developed recurrent disease, and the overall 50-year survival of the group was 70%. Univariate analysis of all possible prognostic factors showed that stage, adjuvant chemotherapy, histological grade and type, surgical rupture of the tumour, intact capsule histologically, clinical finding of ascites and the performance of peritoneal washings were significantly associated with survival. Adequate surgical staging as defined by FIGO was not significantly associated with survival. A multivariate analysis based on the Cox proportional hazard model identified histological grade, adjuvant chemotherapy, patient age and peritoneal washings as having independent prognostic effects. Surprisingly adjuvant chemotherapy and peritoneal washings had negative effects on survival.Conclusions Although a retrospective review has limitations, it would appear that adequate surgical staging and adjuvant chemotherapy confer no benefit in terms of survival in Stage I disease.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesJayasundere, N. ; Smith, B. V. ; Dunn, J. R.
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: An analytic expression is presented for the piezoelectric d constant of a binary piezoelectric 0-3 connectivity composite. The expression is developed under the limiting assumption that the dielectric constant of the ceramic is much greater than the matrix. Predictions made using the theory compare very favorably with available experimental data. A 0-3/1-3 mixed connectivity model is also described for composites in which the average piezoceramic particle size is a significant fraction of the thickness of the composite.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesTischer, M. ; May, F. ; Baberschke, K. ; Hjortstam, O. ; Arvanitis, D. ; Dunn, J. Hunter ; Trygg, J. ; Johansson, B. ; Eriksson, O. ; Wills, J. M.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: By combining MCXD experiments with first principles electronic structure calculations, we demonstrate that the orbital contribution to magnetism can be strongly enhanced at surfaces. This effect is illustrated for Co grown on a Cu(100) surface. The MCXD measurements were performed using the SX 700 plane grating monochromators at BESSY. The Co films were evaporated and characterized in situ, for their cleanness, thickness (1.6–50 ML), and structural order. For a film thickness up to 2.2 ML, measurements of the ac MCXD susceptibility response at a fixed photon energy allowed one to measure the critical temperature, Tc, of the films and their critical properties were characterized in situ. For several samples the MCXD response as a function of the x-ray incidence angle was investigated as well. This allows one to quantify and correct saturation effects that can occur in the measurements. Data were taken in a temperature range between 40 and 350 K, and for many samples measurements were performed at several reduced temperatures, T/Tc. The first layer of Co on the Cu(100) surface shows an enhanced orbital moment, in contrast to the subsequent layers where the orbital moment is bulklike. The lowering of the symmetry, the enhanced spin moment, and the increased value of the density of states at the Fermi level are factors that combine to give the observed enhancements. © 1996 American Institute of Physics. [S0021-8979(96)679608-0]Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesHunter Dunn, J. ; Arvanitis, D. ; Mårtensson, N.
[S.l.] : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The attention that has been focused on the magnetic properties of Fe thin films is due to the presence of several magnetic phases the existence of which may be influenced by the preparation process and subsequent treatment. In particular, Fe grown on the (100) surface of Cu exhibits a crossover from in plane to perpendicular easy magnetization direction as the film thickness decreases below a critical threshold. Here we present an in situ characterization of this system by means of x-ray photoemission and photoabsorption experiments. These two spectroscopies combine to provide a powerful technique for depth profiling the magnetic response as a function of thickness from thin and ultrathin films. In addition photoabsorption measurements in conjunction with magnetic sun rules give access to orbital and spin magnetic moments. We find that for thin fct Fe on Cu(100) the spin moment increases from the bulk bcc value of 2.25 to 3.40 μB. This increase is linked to a relaxation in the interlayer distance and the decrease in coordination number at the surface. The orbital moment also shows an increase from 0.09 to 0.24 μB. This increase, coupled with the reorientation of the easy direction, allows a qualitative consideration of the anisotropy energy that governs this transition. ©1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objective To determine the survival data for the various tumour types of uterine sarcoma and determine the influence of various prognostic factors on survival.Design Retrospective analysis of all uterine sarcoma cases registered in the 15 year period 1967–1981.Setting West Midlands Regional Cancer Registry, serving a catchment area of 2.6 million women.Subjects 423 women registered as having a uterine sarcoma; 367 of these were associated with the two main histological types, leiomyosarcomas (LMS) and mixed mesodermal tumours (MMT).Main outcome measures Duration of survival was taken as the primary endpoint.Results The overall 5-year survival for uterine sarcomas in this series was 31%, with the major prognostic indicator being tumour stage. Survival for mixed mesodermal tumours is similar to other sarcomas despite a tendency towards less differentiation, wider dissemination and a greater age of the patient at diagnosis. Multivariate analysis shows that for cases with similar stage, age and grade, mixed mesodermal tumours have a better prognosis than leiomyosarcomas.Conclusions These results demonstrate the danger of considering each variable in isolation when the relation between variables can lead to spurious significance or lack of significance because of the imbalances in the numbers between groups of prognostic importance. This study underlines the need for an adequate inspection of the infra-abdominal contents at the time of hysterectomy for uterine fibroids.Type of Medium: Electronic ResourceURL: