Search Results - (Author, Cooperation:J. Chong)
-
1Latest Papers from Table of Contents or Articles in PressPerera, D., Tucker, J. W., Brahmbhatt, S., Helal, C. J., Chong, A., Farrell, W., Richardson, P., Sach, N. W.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-01-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: ChemistryPublished by: -
2Latest Papers from Table of Contents or Articles in PressZhou, J., Liu, M., Sun, H., Feng, Y., Xu, L., Chan, A. W. H., Tong, J. H., Wong, J., Chong, C. C. N., Lai, P. B. S., Wang, H. K.-S., Tsang, S.-W., Goodwin, T., Liu, R., Huang, L., Chen, Z., Sung, J. J., Chow, K. L., To, K. F., Cheng, A. S.-L.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-04-07Publisher: BMJ Publishing GroupPrint ISSN: 0017-5749Electronic ISSN: 1468-3288Topics: MedicineKeywords: GutPublished by: -
3Latest Papers from Table of Contents or Articles in PressGao, X. J., Chong, L. S., Kim, M. S., Elowitz, M. B.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-09-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Molecular BiologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressL. Wang ; Y. Zhou ; L. Xu ; R. Xiao ; X. Lu ; L. Chen ; J. Chong ; H. Li ; C. He ; X. D. Fu ; D. Wang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-07-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Crystallography, X-Ray ; Cytosine/*analogs & derivatives/chemistry/metabolism ; DNA Methylation ; DNA Repair ; Epigenesis, Genetic ; Hydrogen Bonding ; Kinetics ; RNA Polymerase II/*chemistry/*metabolism ; Saccharomyces cerevisiae/*enzymology/genetics/metabolism ; Substrate Specificity ; Templates, Genetic ; Thymine DNA Glycosylase/metabolism ; *Transcription Elongation, GeneticPublished by: -
5Latest Papers from Table of Contents or Articles in PressJ. J. Chong ; X. Yang ; C. W. Don ; E. Minami ; Y. W. Liu ; J. J. Weyers ; W. M. Mahoney ; B. Van Biber ; S. M. Cook ; N. J. Palpant ; J. A. Gantz ; J. A. Fugate ; V. Muskheli ; G. M. Gough ; K. W. Vogel ; C. A. Astley ; C. E. Hotchkiss ; A. Baldessari ; L. Pabon ; H. Reinecke ; E. A. Gill ; V. Nelson ; H. P. Kiem ; M. A. Laflamme ; C. E. Murry
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-04-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Arrhythmias, Cardiac/physiopathology ; Calcium/metabolism ; Cell Survival ; Coronary Vessels/physiology ; Cryopreservation ; Disease Models, Animal ; Electrocardiography ; Embryonic Stem Cells/*cytology ; *Heart ; Humans ; Macaca nemestrina ; Male ; Mice ; Myocardial Infarction/*pathology/*therapy ; Myocytes, Cardiac/*cytology ; *Regeneration ; Regenerative Medicine/methodsPublished by: -
6Latest Papers from Table of Contents or Articles in PressM. J. Hawrylycz ; E. S. Lein ; A. L. Guillozet-Bongaarts ; E. H. Shen ; L. Ng ; J. A. Miller ; L. N. van de Lagemaat ; K. A. Smith ; A. Ebbert ; Z. L. Riley ; C. Abajian ; C. F. Beckmann ; A. Bernard ; D. Bertagnolli ; A. F. Boe ; P. M. Cartagena ; M. M. Chakravarty ; M. Chapin ; J. Chong ; R. A. Dalley ; B. D. Daly ; C. Dang ; S. Datta ; N. Dee ; T. A. Dolbeare ; V. Faber ; D. Feng ; D. R. Fowler ; J. Goldy ; B. W. Gregor ; Z. Haradon ; D. R. Haynor ; J. G. Hohmann ; S. Horvath ; R. E. Howard ; A. Jeromin ; J. M. Jochim ; M. Kinnunen ; C. Lau ; E. T. Lazarz ; C. Lee ; T. A. Lemon ; L. Li ; Y. Li ; J. A. Morris ; C. C. Overly ; P. D. Parker ; S. E. Parry ; M. Reding ; J. J. Royall ; J. Schulkin ; P. A. Sequeira ; C. R. Slaughterbeck ; S. C. Smith ; A. J. Sodt ; S. M. Sunkin ; B. E. Swanson ; M. P. Vawter ; D. Williams ; P. Wohnoutka ; H. R. Zielke ; D. H. Geschwind ; P. R. Hof ; S. M. Smith ; C. Koch ; S. G. Grant ; A. R. Jones
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; *Anatomy, Artistic ; Animals ; *Atlases as Topic ; Brain/*anatomy & histology/cytology/*metabolism ; Calbindins ; Databases, Genetic ; Dopamine/metabolism ; *Gene Expression Profiling ; Health ; Hippocampus/cytology/metabolism ; Humans ; In Situ Hybridization ; Internet ; Macaca mulatta/anatomy & histology/genetics ; Male ; Mice ; Neocortex/anatomy & histology/cytology/metabolism ; Oligonucleotide Array Sequence Analysis ; Post-Synaptic Density/genetics ; RNA, Messenger/analysis/genetics ; S100 Calcium Binding Protein G/genetics ; Species Specificity ; Transcriptome/*geneticsPublished by: -
7Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Sixty patients in early labour were randomly allocated to one of three groups. The control group received intrathecal fentanyl 25 µg, the ropivacaine group received intrathecal fentanyl 25 µg and ropivacaine 2.5 mg while the bupivacaine group received intrathecal fentanyl 25 µg and bupivacaine 2.5 mg. The incidence of pruritus was 100% in controls, compared with 85% in the ropivacaine group (not significant) and 75% in the bupivacaine group (p = 0.003). The severity of pruritus was significantly less in the ropivacaine (p = 0.006) and bupivacaine (p = 0.001) groups. Most patients developed pruritus by 30 min. Pruritus above the abdomen was not reduced in patients receiving local anaesthetics. There were no significant differences in the mean pain visual analogue score, systolic blood pressure, maternal heart rate and upper level of reduced pin-prick sensation in the first 30 min. Intrathecal ropivacaine and, more so, intrathecal bupivacaine reduce the incidence and severity of pruritus from intrathecal fentanyl for labour analgesia.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We conducted a randomised, controlled study to investigate the effect of adding a background infusion to patient-controlled epidural analgesia for postoperative pain relief. Forty-two patients scheduled for elective lower abdominal gynaecological surgery received patient-controlled epidural analgesia postoperatively using a mixture of 0.2% ropivacaine and 2.0 μg.ml−1 fentanyl. Patients in group B (n = 20) were given a background infusion of 5 ml.h−1, whereas those in group N (n = 21) were not. There was no difference in pain scores or patient satisfaction scores between the two groups. Patients in group B had a higher total drug consumption (156.8 ± 34.8 ml vs. 89.5 ± 41.0 ml; p 〈 0.0001) and incidence of side-effects (71.4% vs. 30.0%; p = 0.007). Motor blockade during the 24-h study period was also greater in group B (median [range] area under the curve 7.5 [0.0–39.0] h vs. 3.0 [0.0–36.0] h; p = 0.035). We conclude that the addition of a background infusion to patient-controlled epidural anaesthesia is not recommended as it confers no additional benefits.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesGirard, J.E. ; Madhavan, K. ; McMorris, T.C. ; De Loof, A. ; Chong, J. ; Arunachalam, V. ; Schneiderman, H.A. ; Meinwald, J.
Amsterdam : ElsevierStaff ViewISSN: 0020-1790Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Keywords: asymmetric reduction ; enantiotopic group differentiation ; kinetic resolutionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesPhillips, Joel K. ; Chong, J. Michael ; Andersen, John F. ; Burkholder, Wendell E.
Springer
Published 1989Staff ViewISSN: 1570-7458Keywords: Aggregation pheromone ; sitophilate ; 1-ethylpropyl 2-methyl-3-hydroxypentanoate ; stereoisomers ; enantiomers ; Sitophilus granarius ; granary weevil ; Coleoptera ; CurculionidaeSource: Springer Online Journal Archives 1860-2000Topics: BiologyDescription / Table of Contents: Résumé S. granarius L. est un déprédateur important des grains stockés. Le (R*,S*)-1-éthylpropyl 2-méthyl-3-hydroxypentanoate a été identifié en 1987 comme le principal composé du sitophilate, la phéromone mâle d'agrégation de S. granarius. La composition énantiométrique du sitophilate a été déterminée par 3 méthodes: 1) tests biologiques des énantiomères synthétiques (2S,3R) et (2R,3S) du diastéréomère actif (R*,S*); 2) spectrométrie RMN 1H des esters Mosher dérivés de la phéromone naturelle et des sitophilates de synthèse (2S*,3R*)-et (2R*,3S*); 3) comparaison en capillarité GLC des temps de rétention des dérivés naturels de la phéromone et des 2 éniantiomères de synthèse. La combinaison des 3 méthodes confirme que le (2S,3R) énantiomère est la forme active du sitophilate. Le mâle produit 〉96% de l'énantiomère (2S,3R). Il n'y a pas eu attraction de S. granarius par le (2R,3S) sitophilate. S. oryzae L. et S. zeamais Motsch n'ont pas été attirés par le (2S,3R)-sitophilate. L'utilisation du (2S,3R)-1-éthylpropyl 2-méthyl-3-hydroxypentanoate dans les pièges devrait permettre une détection précoce de la présence de S. granarius dans des stocks de grains.Notes: Abstract The enantiomeric composition of sitophilate, the granary weevil [Sitophilus granarius (L.)] male-produced aggregation pheromone [(R*,S*)-1-ethylpropyl 2-methyl-3-hydroxypentanoate)], was determined by three methods: (1) bioassaying the synthetic (2S,3R) and (2R,3S) enantiomers of the active (R*,S*) diastereomer; (2) 1H NMR spectroscopy of Mosher ester derivatives of the natural pheromone and synthetic (2S,3R)-and (2R,3S)-sitophilate; and (3) capillary GLC comparisons of the retention times of derivatized natural pheromone and the two synthetic enantiomers. The combined methods confirmed the (2S,3R) enantiomer as the active form of sitophilate. Male granary weevils were shown to produce 〉96% (2S,3R)-sitophilate. No significant attraction of S. granarius by the (2R,3S) enantiomer was observed. Rice and maize weevils [S. oryzae (L.) and S. zeamais Motschulsky] were not attracted by (2S,3R)-sitophilate.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1432-1904Source: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1432-1904Source: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1432-119XSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Arabinogalactan-protein (AGP, “β-lectin”) was isolated from leek seeds, tested for specificity, conjugated with gold colloids, and used as a cytochemical probe to detect β-linked bound sugars in ultrathin sections of wheat leaves infected with a compatible race of stem rust fungus. Similar sections were probed with other gold-labeled lectins to detect specific sugars. AGP-gold detected β-glycosyl in all fungal walls and in the extrahaustorial matrix. Other lectin gold conjugates localized galactose in all fungal walls except in walls of the haustorial body. Limulus polyphemus lectin bound only to the outermost layer of intercellular hyphal walls of the fungus. Binding of these lectins was inhibited by their appropriate haptens and was diminished or abolished in specimens pretreated with protease, indicating that the target substances in the tissue were proteinaceous or that polysaccharides possessing affinity to the lectin probes had been removed by the enzyme from a proteinaceous matrix by passive escape. Bindig of Lotus tetragonolobus lectin was limited to the two outermost fungal wall layers but was not hapten-inhibitable. Limax flavus lectin, specific for sialic acids, had no affinity to any structure in the sections. In the fungus, the most complex structure was the outermost wall layer of intercellular hyphal cells; it had affinity to all lectins tried so far, except to Limax flavus lectin and to wheat germ lectin included in an earlier study. In the host, AGP and the galactose-specific lectins bound to the inner domain of the wall in areas not in contact with the fungus. At host cell penetration sites, affinity to these lectins often extended througout the host wall, confirming that it is modified at these sites. Pre-treatment with protease had no effect on lectin binding to the host wall. After protease treatment, host starch granules retained affinity to galactose-specific lectins, but lost affinity for AGP.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesChong, J. -M. ; Shiozawa, Y. ; Hayashi, Y. ; Funata, N. ; Takizawa, T. ; Koike, M. ; Fukayama, M.
Springer
Published 1996Staff ViewISSN: 1432-2307Keywords: Acinar cell carcinoma ; Fetal pancreas ; Electron microscopy ; Fibrillary inclusion ; Rough endoplasmic reticulumSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We report a case of pancreatic acinar cell carcinoma which contained a large number of pleomorphic inclusions with fibrillary internal structures and mature zymogen granules. To clarify the significance of fibrillary inclusions in the differentiation of acinar cells of the pancreas, we further investigated fetal pancreases (gestational weeks 16, 17, 19, 20 and 28). We found two types of inclusions: type A, corresponding to fibrillary inclusion of neoplastic acinar cells, was observed only in a 19-week fetus; type B showed a homogeneous density similar to that of zymogen granules. Type B was observed in all the fetuses after the 17th gestational week. Although the type A inclusion might be generated throught a different mechanism than the type B inclusion, the appearance of a large number of fibrillary inclusions in neoplastic acinar cells may represent a transient form of zymogen granule.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1432-2242Keywords: Polymerase chain reaction ; Disease resistance loci ; Oat DNA ; RAPD primers ; Rapid DNA extractionSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary The feasibility of identifying molecular markers linked to disease resistance genes in oats was investigated utilizing random primers in conjunction with polymerase chain reaction technology. A pair of near-isogenic oat lines were screened for polymorphic DNA fragments linked to the stem rust resistance gene Pg3. Two primers were identified which amplified DNA fragments that were polymorphic between the lines analyzed. One primer (ACOpR-2) was shown to be completely linked to the Pg3 locus; the other primer was not linked to either the ACOpR-2 or the Pg3 loci. This type of analysis, combined with rapid leaf disc DNA extraction techniques, offers an effective means of identifying useful molecular markers and of applying them to plant breeding selection strategies.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1615-6102Keywords: Concanavalin A ; Fungus cell surface antigens ; Microwave fixation ; Neoglycoprotein ; Wheat germ lectin ; Wheat stem rustSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary Wheat leaves infected with stem rust (Puccinia graminis tritici) were infiltrated with fixative, subjected to microwave irradiation, and sliced with a vibratome. The slices were probed with antibodies, lectins, or neoglycoproteins, and processed for electron microscopy, In tissue irradiated for 10 sec to 40°C, 45°C, or 50°C, the quality of structural preservation was indistinguishable from that in control tissue subjected to conventional fixation (3 h in fixative at room temperature). The best preservation of fungal antigenic cell surface material was achieved with 10 sec of microwave-induced heating to 45°C in the presence of fixative, followed by 10 min in fixative at room temperature. Under these conditions, twice as many antigenic sites were detected on the fungal surface than in non-irradiated (“power-off” control, or conventionally-fixed) tissue. The microwave fixation protocol with heating to 45°C was used in experiments to probe infected tissue with lectins or neoglycoproteins. Most of these probes had been labelled with biotin, and this label was detected with goat anti-biotin IgG and rabbit anti-goat IgG/gold. The gold markers were localized mainly at some distance outside the outer wall layer of hyphal cells, indirectly confirming the presence of unstained extramural material that had been detected in earlier work in freeze-substituted specimens. Of seven lectins, all with demonstrated ability to bind to cross sections of intercellular hyphal walls, only concanavalin A and wheat germ lectin bound to the fungal surface. Of four neoglycoproteins, α-D-glucosyland α-D-mannosyl-BSA bound to this surface, but only the binding of the glucosyl conjugate was inhibitable with hapten. We concluded that the surface composition of these cells is less complex than previously suggested from studies using post-embedding cytochemistry.Type of Medium: Electronic ResourceURL: