Search Results - (Author, Cooperation:J. C. Knight)

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  1. 1
    B. P. Fairfax ; P. Humburg ; S. Makino ; V. Naranbhai ; D. Wong ; E. Lau ; L. Jostins ; K. Plant ; R. Andrews ; C. McGee ; J. C. Knight
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-03-08
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult ; Antigens, CD14/immunology ; Aryl Hydrocarbon Hydroxylases/genetics ; Basic-Leucine Zipper Transcription Factors/genetics ; CARD Signaling Adaptor Proteins/genetics ; Chromosome Mapping ; Crohn Disease/epidemiology/*genetics ; Cytochrome P-450 CYP1B1 ; Female ; Gene Expression Regulation/*immunology ; *Genetic Predisposition to Disease ; Genetic Variation ; Genome-Wide Association Study ; Humans ; Immunity, Innate/*genetics ; Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics ; Interferon Regulatory Factor-2/genetics ; Interferon Regulatory Factors/genetics ; Interferon-gamma/pharmacology ; Male ; Middle Aged ; Monocytes/drug effects/*immunology ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; Receptors, Purinergic P2/genetics ; Young Adult
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Phillips, P. L. ; Knight, J. C. ; Mangan, B. J. ; Russell, P. St. J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1999
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Near-field optical microscopy is used to image the light propagating in a Si3N4-on-silica film with a strip of deeply etched submicron holes in the center. Fringe patterns created by interference between incident and diffracted guided modes are observed in the smooth waveguide surrounding the large air-hole photonic film. Observation of the fields in the photonic crystal regions indicates that out-of-plane scattering at the smooth/periodic transitions and leakage caused by grating coupling play major roles. The effects of different air-hole sizes and lattice pitches are also explored. © 1999 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.370135

    Articles: DFG German National Licenses
  3. 3
    Phillips, P. L. ; Knight, J. C. ; Pottage, J. M. ; Kakarantzas, G. ; Russell, P. St. J.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    To fully characterize photonic crystal guided wave optical devices, one needs to measure the spatial variation of both the phase and amplitude of the electromagnetic field. In this work, we simultaneously measure the intensity and phase in the near field of both propagating and evanescent fields by incorporating a scanning near-field optical microscope into one arm of a Mach–Zehnder interferometer. We demonstrate the technique by imaging the phase fronts of an evanescent wave formed by total internal reflection and by measuring the phase variation in the LP11 mode in an overmoded optical fiber. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.125812

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Photonic crystal fibres (PCFs) offer greatly enhanced design freedom compared to standard optical fibres. For example, they allow precise control of the chromatic dispersion (CD) profile—the frequency dependence of propagation speed—over a broad wavelength range. This permits studies of ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nature01798

    Articles: DFG German National Licenses
  5. 5
    Couny, F. ; Knight, J. C. ; Birks, T. A. ; Russell, P. St J. ; Benabid, F.

    [s.l.] : Macmillian Magazines Ltd.
    Published 2005
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Gas-phase materials are used in a variety of laser-based applications—for example, in high-precision frequency measurement, quantum optics and nonlinear optics. Their full potential has however not been realized because of the lack of a suitable technology for creating gas cells that ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nature03349

    Articles: DFG German National Licenses
  6. 6
    Knight, J. C. ; Whitehead, A. J. ; Page, T. F.
    Springer
    Published 1992
    Staff View
    ISSN:
    1573-4803
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract Ultra-low-load indentation (nanoindentation) experiments have been used to investigate the load-displacement characteristics of two types of hydrogenated carbon films (a “hard” and a “soft” version ∼230 and ∼210 nm thick, respectively) deposited from methane on to (1 0 0) single-crystal silicon wafers by a radio frequency plasma-assisted chemical vapour deposition process. Further, the technique was used to explore the changes in the properties of the films with heat treatment in vacuum at temperatures of up to 650°C. In all cases, the elastic and plastic properties of the films were compared at indentation loads in the range 0–60 mN, the higher loads causing indentor displacements greater than the thickness of the films. For the harder, stiffer coating, penetration resistance was found to decrease with increasing indenter displacement, reflecting the greater load-carrying role taken by the softer silicon with increasing applied load. However, for the softer coating, penetration resistance generally increased with displacement, perhaps reflecting progressive compaction of the coating in addition to the increasing role of the silicon. In both cases, heat treatment severely degraded the mechanical properties of the films due to thermally induced chemical changes and, in the case of the “hard” coating, relaxation of residual stresses. Scanning electron microscopy of both nanoindentations and low-load microhardness indentations clearly reveals the deformation mechanisms associated with contact stresses to include flow and fracture of the film and interfacial decohesion.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00545479

    Articles: DFG German National Licenses
  7. 7
    Knight, J. C. ; Wagh, Arun S. ; Reid, W. A.
    Springer
    Published 1986
    Staff View
    ISSN:
    1573-4803
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract This paper summarizes the development of engineering ceramics made from bauxite waste (“red mud”) produced in the alumina industry in Jamaica. Test specimens are fabricated from powders by sintering. For a particle size distribution of less than 75μm in the starting powders and firing temperatures in the range of 1000 to 1100° C various mechanical properties are measured. These include fracture toughness (K Ic), modulus of rupture (MOR), compression strength (σ c) and Brinell hardness. While apparent porosity varies between 40 and 48%, K Ic is found to vary between 0.39 and 0.68 MN m−3/2. The values are compared with those measured for commercial ceramic tiles and also with ceramics of magnesia and calcium zirconate. Within the fabrication temperature range studied the MOR ranges between 17.23 and 27.09 MN m−2, compressive strength between 42.0 and 83.9 MN m−2 and Brinell hardness between 26.2 and 59.9 kg mm−2. With the aid of scanning electron microscopy and a basic knowledge of the physicochemical properties of the mud an attempt is made to explain the high strength and toughness achieved. The ready availability of raw material and the relatively low firing temperatures required for suitable engineering products should keep the production costs low for “red mud ceramics”.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00547967

    Articles: DFG German National Licenses
  8. 8
    Knight, J. C. ; Knight, M. ; Smith, M. J.
    Springer
    Published 2000
    Staff View
    ISSN:
    1435-4373
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s100960000351

    Articles: DFG German National Licenses