Search Results - (Author, Cooperation:J. Behr)
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1Latest Papers from Table of Contents or Articles in PressTyler E. Culp, Yue-xiao Shen, Michael Geitner, Mou Paul, Abhishek Roy, Michael J. Behr, Steve Rosenberg, Junsi Gu, Manish Kumar, Enrique D. Gomez
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-08-29Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
2Latest Papers from Table of Contents or Articles in PressX. Gan ; O. Stegle ; J. Behr ; J. G. Steffen ; P. Drewe ; K. L. Hildebrand ; R. Lyngsoe ; S. J. Schultheiss ; E. J. Osborne ; V. T. Sreedharan ; A. Kahles ; R. Bohnert ; G. Jean ; P. Derwent ; P. Kersey ; E. J. Belfield ; N. P. Harberd ; E. Kemen ; C. Toomajian ; P. X. Kover ; R. M. Clark ; G. Ratsch ; R. Mott
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-08-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Arabidopsis/classification/*genetics ; Arabidopsis Proteins/genetics ; Base Sequence ; *Gene Expression Profiling ; Gene Expression Regulation, Plant/*genetics ; Genes, Plant/genetics ; Genome, Plant/*genetics ; Genomics ; Haplotypes/genetics ; INDEL Mutation/genetics ; Molecular Sequence Annotation ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Proteome/genetics ; Seedlings/genetics ; Sequence Analysis, DNA ; Transcription, Genetic/*geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressJ. M. Lorch ; C. U. Meteyer ; M. J. Behr ; J. G. Boyles ; P. M. Cryan ; A. C. Hicks ; A. E. Ballmann ; J. T. Coleman ; D. N. Redell ; D. M. Reeder ; D. S. Blehert
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-10-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Ascomycota/*pathogenicity ; Chiroptera/anatomy & histology/*microbiology ; Europe/epidemiology ; Mycoses/microbiology/mortality/transmission/*veterinary ; North America/epidemiology ; Nose/*microbiology/*pathology ; Survival Analysis ; Syndrome ; Wings, Animal/microbiology/pathologyPublished by: -
4Articles: DFG German National LicensesLoeffler, J. Ph. ; Barthel, F. ; Feltz, P. ; Behr, J. P. ; Sassone-Corsi, P. ; Feltz, A.
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: A simple and efficient transfection technique based on lipopolyamine-coated DNA that can be used for gene transfer in cerebellar granular neurons is described. Gene transfer is achieved by exposure of cells to a DNA/lipid complex obtained by simple mixing of lipopolyamine and plasmid DNA. This procedure may represent a general tool of physiological investigations in primary cells. We show that the promoters of the introduced chimera genes are regulated by their respective trans-acting factors and may be modulated via membrane receptors and second messengers. This procedure has no noticeable toxic effects, nor does it seem to interfere with complex physiological behavior like neuronal differentiation.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Intracellular recordings were performed to examine the perforant path projection from layer III of the entorhinal cortex to the subiculum in rat combined hippocampal–entorhinal cortex slices. Electrical stimulation in the medial entorhinal cortex layer III caused short latency combined excitatory and inhibitory synaptic responses in subicular cells.In the presence of the GABAA antagonist bicuculline and the GABAB antagonist CGP-55845 A inhibition was blocked and isolated AMPA- or NMDA receptor-mediated EPSPs could be elicited. After application of the non-NMDA antagonist NBQX and the NMDA antagonist APV excitatory responses were completely blocked indicating a glutamatergic input from the neurons of the medial entorhinal cortex layer III. By stimulation from a close (〈 0.2 mm) position in the presence of NBQX and APV and either CGP-55845 A or bicuculline we could record monosynaptic fast GABAA or slow GABAB receptor-mediated IPSPs, respectively.We compared synaptic responses in subicular cells induced by stimulation in the medial entorhinal cortex layer III with responses elicited by stimulation of afferent fibres in the alveus. The EPSPs of subicular cells induced by stimulation of alvear fibres could be significantly augmented by simultaneous activation of perforant path fibres originating in the medial entorhinal cortex layer III, while delayed activation of alvear fibres after stimulation of the perforant path resulted in a weak inhibition of the alveus evoked EPSPs.Thus, the perforant path projection activates monosynaptic excitation of subicular neurons. Therefore the entorhinal cortex does not only function as an important input structure of the hippocampal formation but is also able to modulate the hippocampal output via the entorhinal–subicular circuit.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesHEIN, R. ; BEHR, J. ; HÜNDGEN, M. ; HUNZELMANN, N. ; MEURER, M. ; BRAUN-FALCO, O. ; URBANSKI, A. ; KRIEG, T.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Numerous drugs have been recommended for the treatment of systemic sclerosis, but without any significant effect on the fibrotic stage of this disorder. Because recombinant gamma-interferon (γ-IFN) is a potent and selective inhibitor of fibroblast proliferation and collagen production by human dermal fibroblasts in vitro, we assessed the effects of γ-IFN treatment on the skin and on pulmonary function in patients with systemic sclerosis. Fourteen patients entered the study, and nine completed the 12-month trial. Fifty micrograms/day of γ-IFN was administered subcutaneously 3 days per week. At the end of the 12-month treatment period a significant improvement was observed in total skin score, and blood gas analysis showed a significant increase in Pa O2 during therapy with γ-interferon. Other clinical parameters (dysphagia, Raynaud's phenomenon, cardiac involvement) were not altered significantly. No serious adverse effects were noted. These results suggest a beneficial effect of γ-IFN on the cutaneous fibrotic abnormalities and on lung fibrosis in systemic sclerosis.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1434-601XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Zusammenfassung Für die Streuung positiv geladener Myonen von etwa 25 MeV an schweren Kernen wird der Einfluß eines Kernquadrupolmomentes auf die Streuverteilung berechnet. Unter der Voraussetzung, daß das zur kugelsymmetrischen Wechselwirkung hinzutretende Quadrupolpotential, sowie die Spin-Bahn-Kopplung als Störungen betrachtet werden dürfen, wird die Dirac-Gleichung durch ein Näherungsverfahren gelöst, das der Bornschen Rechenmethode nachgebildet ist, im Gegensatz zu dieser jedoch das zur kugelsymmetrischen Wechselwirkung gehörende Wellenfeld als Ausgangslösung benutzt. Die erhaltene Streuverteilung wird mit der in gewöhnlicher Bornscher Näherung berechneten verglichen.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1434-601XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Zusammenfassung Zur Berechnung der Streuung geladener Teilchen an Kernen endlicher Ausdehnung wird eine Erweiterung derBornschen Näherung angegeben. Da die Wechselwirkung der Stoßpartner über ein im Kernbereich modifiziertesCoulomb-Feld geschieht, wird als Ausgangsfunktion für die Näherung an Stelle der sonst benutzten ebenen Welle eineCoulomb-Eigenfunktion benutzt.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesErlinger, R. ; Rauh, G. ; Behr, J. ; Schumacher, U. ; Welsch, U. ; Zöllner, N.
Springer
Published 1991Staff ViewISSN: 1432-1440Keywords: Autoantibodies ; Pneumocytes type II ; Clara cells ; Pulmonary surfactant ; Pulmonary fibrosis ; Sarcoidosis ; Rheumatoid arthritisSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Several experimental findings suggest an association between interstitial lung diseases and autoantibodies. Antibodies against lung tissue including pneumocytes type II in patients suffering from idiopathic pulmonary fibrosis (IPF) were reported in recent years. In this investigation the serum of 103 persons (10 with IPF, 23 with M. Boeck, 18 with rheumatoid arthritis (RA) and 52 healthy controls) was examined for autoantibodies against pneumocytes type II and Clara cells by indirect immunofluorescence on human lung tissue. These antibodies against both cell types are an additional proof for common antigens in pneumocytes type II and Clara cells. The autoantibodies were present in similar frequency in the 4 groups (IPF: 20%, M. Boeck: 26.1%, RA: 22.2% and 23.1% of the healthy controls). So no significant association was found between the antibodies and the interstitial lung diseases. A role of the antibodies in the pathogenesis of the diseases, however, can not be excluded by this study. A possible role as parameter of development of interstitial lung diseases should be subject to further investigations in form of a prospective follow up study.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesBehr, J.-P. ; Bergdoll, M. ; Chevrier, B. ; Dumas, P. ; Lehn, J.-M. ; Moras, D.
Amsterdam : ElsevierStaff ViewISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0029-5582Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0029-5582Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesSchelling, G. ; Stoll, C. ; Vogelmeier, C. ; Hummel, T. ; Behr, J. ; Kapfhammer, H.-P. ; Rothenhäusler, H.-B. ; Haller, M. ; Durst, K. ; Krauseneck, T. ; Briegel, J.
Springer
Published 2000Staff ViewISSN: 1432-1238Keywords: Key words Acute respiratory distress syndrome ; Recovery ; Pulmonary function ; Outcome ; Sepsis ; Health-related quality of lifeSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Objective: We performed a follow-up cohort analysis in order to delineate the correlation between pulmonary function (PF) and health-related quality of life (HRQL) in patients after ARDS.¶Design: Follow-up cohort study.¶Setting: A 20-bed ICU of a university teaching hospital.¶Patients: A cohort of 50 long-term survivors of ARDS.¶Measurements and results: Measurements of PF (FVC, FEV1, TLC, DLCO) and HRQL (SF-36 Health Status Questionnaire) were made 5.5 years (median value) after discharge from the ICU. Impairments in PF (defined as PF results below 80 % of the predicted value) were frequent but generally mild. Twenty patients had a single PF impairment (with limitations in FEV1/FVC ratio in 12 patients being the most common), four patients had two (with DLCO and FEV1/FVC ratio impairment the most common) and three patients had pathologic results in three PF tests (FEV1/FVC ratio, TLC and capillary pO2 during exercise in one case, FVC, TLC and capillary pO2 during exercise in the second patient and FVC, TLC and DLCO in the third). Compared to normal controls, survivors of ARDS showed impairments in all SF-36 health dimensions (p 〈 0.001). Patients with multiple (〉 1) PF impairments described the lowest HRQL with major limitations in all SF-36 categories (p 〈 0.037) including physical and mental summary scores (36.5 vs 46.9, p = 0.037 and 31.3 vs 51.4, p = 0.003) when compared to patients with no or only one PF impairment.¶Conclusions: Long-term survivors of ARDS have a significant reduction in HRQL and the presence of multiple PF impairments is associated with maximal decrements in HRQL.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1432-2102Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: