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1M. Parker ; K. M. Mohankumar ; C. Punchihewa ; R. Weinlich ; J. D. Dalton ; Y. Li ; R. Lee ; R. G. Tatevossian ; T. N. Phoenix ; R. Thiruvenkatam ; E. White ; B. Tang ; W. Orisme ; K. Gupta ; M. Rusch ; X. Chen ; P. Nagahawhatte ; E. Hedlund ; D. Finkelstein ; G. Wu ; S. Shurtleff ; J. Easton ; K. Boggs ; D. Yergeau ; B. Vadodaria ; H. L. Mulder ; J. Becksfort ; P. Gupta ; R. Huether ; J. Ma ; G. Song ; A. Gajjar ; T. Merchant ; F. Boop ; A. A. Smith ; L. Ding ; C. Lu ; K. Ochoa ; D. Zhao ; R. S. Fulton ; L. L. Fulton ; E. R. Mardis ; R. K. Wilson ; J. R. Downing ; D. R. Green ; J. Zhang ; D. W. Ellison ; R. J. Gilbertson
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-02-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/genetics/metabolism ; Animals ; Base Sequence ; Brain Neoplasms/genetics/metabolism/pathology ; Cell Line ; Cell Nucleus/metabolism ; *Cell Transformation, Neoplastic/genetics ; Chromosomes, Human, Pair 11/genetics ; Ependymoma/*genetics/*metabolism/pathology ; Female ; Humans ; Mice ; Models, Genetic ; Molecular Sequence Data ; NF-kappa B/genetics/*metabolism ; Neural Stem Cells/metabolism/pathology ; Oncogene Proteins, Fusion/genetics/metabolism ; Phosphoproteins/genetics/metabolism ; Proteins/genetics/*metabolism ; *Signal Transduction ; Transcription Factor RelA/genetics/*metabolism ; Translocation, Genetic/geneticsPublished by: -
2G. Robinson ; M. Parker ; T. A. Kranenburg ; C. Lu ; X. Chen ; L. Ding ; T. N. Phoenix ; E. Hedlund ; L. Wei ; X. Zhu ; N. Chalhoub ; S. J. Baker ; R. Huether ; R. Kriwacki ; N. Curley ; R. Thiruvenkatam ; J. Wang ; G. Wu ; M. Rusch ; X. Hong ; J. Becksfort ; P. Gupta ; J. Ma ; J. Easton ; B. Vadodaria ; A. Onar-Thomas ; T. Lin ; S. Li ; S. Pounds ; S. Paugh ; D. Zhao ; D. Kawauchi ; M. F. Roussel ; D. Finkelstein ; D. W. Ellison ; C. C. Lau ; E. Bouffet ; T. Hassall ; S. Gururangan ; R. Cohn ; R. S. Fulton ; L. L. Fulton ; D. J. Dooling ; K. Ochoa ; A. Gajjar ; E. R. Mardis ; R. K. Wilson ; J. R. Downing ; J. Zhang ; R. J. Gilbertson
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CREB-Binding Protein/genetics ; Cadherins/genetics ; Cdh1 Proteins ; Cell Cycle Proteins/deficiency/genetics ; Cell Lineage ; Cerebellar Neoplasms/*classification/*genetics/pathology ; Child ; DEAD-box RNA Helicases/genetics ; DNA Copy Number Variations ; DNA Helicases/genetics ; DNA Mutational Analysis ; Disease Models, Animal ; Genome, Human/genetics ; Genomics ; Hedgehog Proteins/metabolism ; Histone Demethylases/genetics ; Histones/metabolism ; Humans ; Medulloblastoma/*classification/*genetics/pathology ; Methylation ; Mice ; Mutation/*genetics ; Nuclear Proteins/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Transcription Factors/genetics ; Wnt Proteins/metabolism ; beta Catenin/geneticsPublished by: -
3P. Ntziachristos ; A. Tsirigos ; G. G. Welstead ; T. Trimarchi ; S. Bakogianni ; L. Xu ; E. Loizou ; L. Holmfeldt ; A. Strikoudis ; B. King ; J. Mullenders ; J. Becksfort ; J. Nedjic ; E. Paietta ; M. S. Tallman ; J. M. Rowe ; G. Tonon ; T. Satoh ; L. Kruidenier ; R. Prinjha ; S. Akira ; P. Van Vlierberghe ; A. A. Ferrando ; R. Jaenisch ; C. G. Mullighan ; I. Aifantis
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Benzazepines/pharmacology ; Epigenesis, Genetic/drug effects ; Histone Demethylases/genetics/*metabolism ; Histones/chemistry/metabolism ; Jumonji Domain-Containing Histone Demethylases/antagonists & ; inhibitors/*metabolism ; Lysine/metabolism ; Methylation/drug effects ; Mice ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug ; therapy/*enzymology/genetics/pathology ; Pyrimidines/pharmacology ; Tumor Suppressor Proteins/genetics/metabolismPublished by: -
4J. Zhang ; L. Ding ; L. Holmfeldt ; G. Wu ; S. L. Heatley ; D. Payne-Turner ; J. Easton ; X. Chen ; J. Wang ; M. Rusch ; C. Lu ; S. C. Chen ; L. Wei ; J. R. Collins-Underwood ; J. Ma ; K. G. Roberts ; S. B. Pounds ; A. Ulyanov ; J. Becksfort ; P. Gupta ; R. Huether ; R. W. Kriwacki ; M. Parker ; D. J. McGoldrick ; D. Zhao ; D. Alford ; S. Espy ; K. C. Bobba ; G. Song ; D. Pei ; C. Cheng ; S. Roberts ; M. I. Barbato ; D. Campana ; E. Coustan-Smith ; S. A. Shurtleff ; S. C. Raimondi ; M. Kleppe ; J. Cools ; K. A. Shimano ; M. L. Hermiston ; S. Doulatov ; K. Eppert ; E. Laurenti ; F. Notta ; J. E. Dick ; G. Basso ; S. P. Hunger ; M. L. Loh ; M. Devidas ; B. Wood ; S. Winter ; K. P. Dunsmore ; R. S. Fulton ; L. L. Fulton ; X. Hong ; C. C. Harris ; D. J. Dooling ; K. Ochoa ; K. J. Johnson ; J. C. Obenauer ; W. E. Evans ; C. H. Pui ; C. W. Naeve ; T. J. Ley ; E. R. Mardis ; R. K. Wilson ; J. R. Downing ; C. G. Mullighan
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-01-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Age of Onset ; Child ; DNA Copy Number Variations/genetics ; Genes, ras/genetics ; Genetic Predisposition to Disease/*genetics ; Genome, Human/genetics ; Genomics ; Hematopoiesis/genetics ; Histones/metabolism ; Humans ; Janus Kinases/genetics/metabolism ; Leukemia, Myeloid, Acute/drug therapy/genetics/pathology ; Molecular Sequence Data ; Mutation/*genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy/*genetics/pathology ; Receptors, Interleukin-7/genetics ; Sequence Analysis, DNA ; Signal Transduction/genetics ; Stem Cells/metabolism/pathology ; T-Lymphocytes/metabolism/pathology ; Translocation, Genetic/geneticsPublished by: