Search Results - (Author, Cooperation:J. B. French)

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  1. 1
    J. B. French ; S. A. Jones ; H. Deng ; A. M. Pedley ; D. Kim ; C. Y. Chan ; H. Hu ; R. J. Pugh ; H. Zhao ; Y. Zhang ; T. J. Huang ; Y. Fang ; X. Zhuang ; S. J. Benkovic
    American Association for the Advancement of Science (AAAS)
    Published 2016
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    HeLa Cells ; Humans ; Microscopy ; Mitochondria/*metabolism/ultrastructure ; Purines/*metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    French, J. B. ; Darcie, T. E.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1986
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    In previous publications a new theoretical approach to ion transport in neutral gases, based on the integral Boltzmann equation, was reported. The method is applicable to determining the evolution of a source of ions which are electrostatically accelerated through a not necessarily uniform neutral gas target. This paper presents experimental corroboration for two gas target configurations; (1) spatially uniform and (2) free-jet expansion, for protonated dimethyl-sulfoxide ions and nitrogen gas. The theory was in best agreement for the free-jet target and both configurations were used to determine an ion–molecule hard-sphere cross section of 3.6±0.15 A(ring).
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Halemane, T. R. ; French, J. B.
    Springer
    Published 1982
    Staff View
    ISSN:
    1434-601X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Linear-energy weighted sum-rules (LEWSR) are calculated for isovector magnetic dipole transitions from the ground state in some (d s)-shell nuclei. It is found that the well-known Kurath sum rule is inadequate to explain the experimental transition strengths in these nuclei. A significant contribution to the sum-rule is seen to arise from the two-body part of the Hamiltonian. The calculations are made using the spectral distribution methods.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Lovett, A. M. ; Reid, N. M. ; Buckley, J. A. ; French, J. B. ; Cameron, D. M.

    Chichester : Wiley-Blackwell
    Published 1979
    Staff View
    ISSN:
    0306-042X
    Keywords:
    Chemistry ; Analytical Chemistry and Spectroscopy
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    A new technique is reported resulting in the direct, instantaneous analyses of trace compounds in breath. The analyses were performed using a commercial atmospheric pressure chemical ionization mass spectrometer (TAGA TM 2000 APCI mass spectrometer). A known flow of breath sample is introduced into the ionization region of the mass spectrometer. The study includes the measurement and monitoring in real-time, of breath ammonia during a 24 hour and a 48 hour period. The ammonia profiles indicate a personalized daily pattern associated with each subject. This method appears to be of potential value in routine detection and treatment of hyperammonemia patients. Results also show that it is possible to obtain instantaneous analyses of several naturally occurring metabolites and other substances on breath in the ppm to ppt range, suggesting a number of diagnostic research applications.
    Additional Material:
    9 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Dawson, P. H. ; French, J. B. ; Buckley, J. A. ; Douglas, D. J. ; Simmons, D.

    Chichester : Wiley-Blackwell
    Published 1982
    Staff View
    ISSN:
    0030-493X
    Keywords:
    Chemistry ; Analytical Chemistry and Spectroscopy
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Triple quadrupoles are becoming widely used in sequential mass spectrometry. The observed spectra are very dependent upon the choice of instrument parameters such as the gas target density, the mode of operation of the central quadrupole, and the direct current levels of the quadrupoles (rod-offsets) which determine the collision energy and the maximum mass resolutions in each analysing quadrupole. The influence of each of the instrument parameters is discussed with examples of experimental measurements of performance, and the optimum choice of modes of operation is determined.
    Additional Material:
    7 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Dawson, P. H. ; French, J. B. ; Buckley, J. A. ; Douglas, D. J. ; Simmons, D.

    Chichester : Wiley-Blackwell
    Published 1982
    Staff View
    ISSN:
    0030-493X
    Keywords:
    Chemistry ; Analytical Chemistry and Spectroscopy
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    A detailed exploration of the application of triple quadrupoles in sequential mass spectrometry has been carried out using dimethylmorpholinophosphoramidate as a case study of an ion of relatively high mass and complex structure. Both metastable ion decomposition and dissociation by low energy collision were examined. Variation of the basic instrument parameters allowed the investigation of the cross-section for dissociation as a function of collision energy, the change in fragmentation patterns with collision energy, the kinetic energy distributions of daughter ions and the overall kinetics of dissociation in a succession of ion decomposition sequences giving daughter and granddaughter ions. The daughter ions could also be produced in the source region and examined separately so that a genealogical tree could be established.
    Additional Material:
    12 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses