Search Results - (Author, Cooperation:J. A. Walker)
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1L. Carbone ; R. A. Harris ; S. Gnerre ; K. R. Veeramah ; B. Lorente-Galdos ; J. Huddleston ; T. J. Meyer ; J. Herrero ; C. Roos ; B. Aken ; F. Anaclerio ; N. Archidiacono ; C. Baker ; D. Barrell ; M. A. Batzer ; K. Beal ; A. Blancher ; C. L. Bohrson ; M. Brameier ; M. S. Campbell ; O. Capozzi ; C. Casola ; G. Chiatante ; A. Cree ; A. Damert ; P. J. de Jong ; L. Dumas ; M. Fernandez-Callejo ; P. Flicek ; N. V. Fuchs ; I. Gut ; M. Gut ; M. W. Hahn ; J. Hernandez-Rodriguez ; L. W. Hillier ; R. Hubley ; B. Ianc ; Z. Izsvak ; N. G. Jablonski ; L. M. Johnstone ; A. Karimpour-Fard ; M. K. Konkel ; D. Kostka ; N. H. Lazar ; S. L. Lee ; L. R. Lewis ; Y. Liu ; D. P. Locke ; S. Mallick ; F. L. Mendez ; M. Muffato ; L. V. Nazareth ; K. A. Nevonen ; M. O'Bleness ; C. Ochis ; D. T. Odom ; K. S. Pollard ; J. Quilez ; D. Reich ; M. Rocchi ; G. G. Schumann ; S. Searle ; J. M. Sikela ; G. Skollar ; A. Smit ; K. Sonmez ; B. ten Hallers ; E. Terhune ; G. W. Thomas ; B. Ullmer ; M. Ventura ; J. A. Walker ; J. D. Wall ; L. Walter ; M. C. Ward ; S. J. Wheelan ; C. W. Whelan ; S. White ; L. J. Wilhelm ; A. E. Woerner ; M. Yandell ; B. Zhu ; M. F. Hammer ; T. Marques-Bonet ; E. E. Eichler ; L. Fulton ; C. Fronick ; D. M. Muzny ; W. C. Warren ; K. C. Worley ; J. Rogers ; R. K. Wilson ; R. A. Gibbs
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-09-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Evolution, Molecular ; Genome/*genetics ; Hominidae/classification/genetics ; Humans ; Hylobates/*classification/*genetics ; *Karyotype ; Molecular Sequence Data ; *Phylogeny ; Retroelements/genetics ; Selection, Genetic ; Transcription Termination, GeneticPublished by: -
2P. H. Sudmant ; T. Rausch ; E. J. Gardner ; R. E. Handsaker ; A. Abyzov ; J. Huddleston ; Y. Zhang ; K. Ye ; G. Jun ; M. Hsi-Yang Fritz ; M. K. Konkel ; A. Malhotra ; A. M. Stutz ; X. Shi ; F. Paolo Casale ; J. Chen ; F. Hormozdiari ; G. Dayama ; K. Chen ; M. Malig ; M. J. Chaisson ; K. Walter ; S. Meiers ; S. Kashin ; E. Garrison ; A. Auton ; H. Y. Lam ; X. Jasmine Mu ; C. Alkan ; D. Antaki ; T. Bae ; E. Cerveira ; P. Chines ; Z. Chong ; L. Clarke ; E. Dal ; L. Ding ; S. Emery ; X. Fan ; M. Gujral ; F. Kahveci ; J. M. Kidd ; Y. Kong ; E. W. Lameijer ; S. McCarthy ; P. Flicek ; R. A. Gibbs ; G. Marth ; C. E. Mason ; A. Menelaou ; D. M. Muzny ; B. J. Nelson ; A. Noor ; N. F. Parrish ; M. Pendleton ; A. Quitadamo ; B. Raeder ; E. E. Schadt ; M. Romanovitch ; A. Schlattl ; R. Sebra ; A. A. Shabalin ; A. Untergasser ; J. A. Walker ; M. Wang ; F. Yu ; C. Zhang ; J. Zhang ; X. Zheng-Bradley ; W. Zhou ; T. Zichner ; J. Sebat ; M. A. Batzer ; S. A. McCarroll ; R. E. Mills ; M. B. Gerstein ; A. Bashir ; O. Stegle ; S. E. Devine ; C. Lee ; E. E. Eichler ; J. O. Korbel
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-10-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Genetic Predisposition to Disease ; Genetic Variation/*genetics ; Genetics, Medical ; Genetics, Population ; Genome, Human/*genetics ; Genome-Wide Association Study ; Genomics ; Genotype ; Haplotypes/genetics ; Homozygote ; Humans ; Molecular Sequence Data ; Mutation Rate ; *Physical Chromosome Mapping ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; Sequence Analysis, DNA ; Sequence Deletion/geneticsPublished by: -
3R. E. Mills ; K. Walter ; C. Stewart ; R. E. Handsaker ; K. Chen ; C. Alkan ; A. Abyzov ; S. C. Yoon ; K. Ye ; R. K. Cheetham ; A. Chinwalla ; D. F. Conrad ; Y. Fu ; F. Grubert ; I. Hajirasouliha ; F. Hormozdiari ; L. M. Iakoucheva ; Z. Iqbal ; S. Kang ; J. M. Kidd ; M. K. Konkel ; J. Korn ; E. Khurana ; D. Kural ; H. Y. Lam ; J. Leng ; R. Li ; Y. Li ; C. Y. Lin ; R. Luo ; X. J. Mu ; J. Nemesh ; H. E. Peckham ; T. Rausch ; A. Scally ; X. Shi ; M. P. Stromberg ; A. M. Stutz ; A. E. Urban ; J. A. Walker ; J. Wu ; Y. Zhang ; Z. D. Zhang ; M. A. Batzer ; L. Ding ; G. T. Marth ; G. McVean ; J. Sebat ; M. Snyder ; J. Wang ; E. E. Eichler ; M. B. Gerstein ; M. E. Hurles ; C. Lee ; S. A. McCarroll ; J. O. Korbel
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: DNA Copy Number Variations/*genetics ; Gene Duplication/genetics ; Genetic Predisposition to Disease/genetics ; *Genetics, Population ; Genome, Human/*genetics ; *Genomics ; Genotype ; Humans ; Mutagenesis, Insertional/genetics ; Reproducibility of Results ; Sequence Analysis, DNA ; Sequence Deletion/geneticsPublished by: -
4Bardill, J., Bader, A. C., Garrison, N. A., Bolnick, D. A., Raff, J. A., Walker, A., Malhi, R. S., the Summer internship for INdigenous peoples in Genomics (SING) Consortium
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, SociologyPublished by: -
5D. P. Locke ; L. W. Hillier ; W. C. Warren ; K. C. Worley ; L. V. Nazareth ; D. M. Muzny ; S. P. Yang ; Z. Wang ; A. T. Chinwalla ; P. Minx ; M. Mitreva ; L. Cook ; K. D. Delehaunty ; C. Fronick ; H. Schmidt ; L. A. Fulton ; R. S. Fulton ; J. O. Nelson ; V. Magrini ; C. Pohl ; T. A. Graves ; C. Markovic ; A. Cree ; H. H. Dinh ; J. Hume ; C. L. Kovar ; G. R. Fowler ; G. Lunter ; S. Meader ; A. Heger ; C. P. Ponting ; T. Marques-Bonet ; C. Alkan ; L. Chen ; Z. Cheng ; J. M. Kidd ; E. E. Eichler ; S. White ; S. Searle ; A. J. Vilella ; Y. Chen ; P. Flicek ; J. Ma ; B. Raney ; B. Suh ; R. Burhans ; J. Herrero ; D. Haussler ; R. Faria ; O. Fernando ; F. Darre ; D. Farre ; E. Gazave ; M. Oliva ; A. Navarro ; R. Roberto ; O. Capozzi ; N. Archidiacono ; G. Della Valle ; S. Purgato ; M. Rocchi ; M. K. Konkel ; J. A. Walker ; B. Ullmer ; M. A. Batzer ; A. F. Smit ; R. Hubley ; C. Casola ; D. R. Schrider ; M. W. Hahn ; V. Quesada ; X. S. Puente ; G. R. Ordonez ; C. Lopez-Otin ; T. Vinar ; B. Brejova ; A. Ratan ; R. S. Harris ; W. Miller ; C. Kosiol ; H. A. Lawson ; V. Taliwal ; A. L. Martins ; A. Siepel ; A. Roychoudhury ; X. Ma ; J. Degenhardt ; C. D. Bustamante ; R. N. Gutenkunst ; T. Mailund ; J. Y. Dutheil ; A. Hobolth ; M. H. Schierup ; O. A. Ryder ; Y. Yoshinaga ; P. J. de Jong ; G. M. Weinstock ; J. Rogers ; E. R. Mardis ; R. A. Gibbs ; R. K. Wilson
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-01-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Centromere/genetics ; Cerebrosides/metabolism ; Chromosomes ; Evolution, Molecular ; Female ; Gene Rearrangement/genetics ; Genetic Speciation ; *Genetic Variation ; Genetics, Population ; Genome/*genetics ; Humans ; Male ; Phylogeny ; Pongo abelii/*genetics ; Pongo pygmaeus/*genetics ; Population Density ; Population Dynamics ; Species SpecificityPublished by: -
6Dickinson, G. S., Levenson, E. A., Walker, J. A., Kearney, J. F., Alugupalli, K. R.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-08-07Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
7Staff View
Publication Date: 2018-09-14Publisher: American Physical Society (APS)Print ISSN: 1539-3755Electronic ISSN: 1550-2376Topics: PhysicsKeywords: Statistical PhysicsPublished by: -
8Pandya, K. D., Palomo-Caturla, I., Walker, J. A., K. Sandilya, V., Zhong, Z., Alugupalli, K. R.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-06-05Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
9M. Songvilay, E. E. Rodriguez, R. Lindsay, M. A. Green, H. C. Walker, J. A. Rodriguez-Rivera, and C. Stock
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-08-22Publisher: American Physical Society (APS)Print ISSN: 0031-9007Electronic ISSN: 1079-7114Topics: PhysicsKeywords: Condensed Matter: Electronic Properties, etc.Published by: -
10Staff View
ISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The phagocytosis of various strains of Actinomyces viscosus was studied using murine peritoneal macrophages and in vitro assay procedures. A. viscosus M100 was readily phagocytized when compared to controls using Staphylococcus epidermidis. The phagocytic uptake was enhanced by the addition of opsonic antibody and complement. The virulent (V) and avirulent (AV) strains of A. viscosus T14 were, however, refractory to phagocytosis. Indeed, the presence of specific antibody and complement had no enhancing effect on phagocytosis of these strains. Heat killed T14-V and T14-AV exhibited phagocytic indices similar to those of non-opsonized S. epidermidis. The inhibitory effect of A. viscosus T14 is dependent upon bacterial viability and does not alter the viability of the cultured macrophages. Since both T14-V and T14-AV were capable of blocking phagocytosis, the response does not appear dependent on the ascribed virulence factors.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1432-0673Keywords: simple fluid ; viscoelastic ; fading memory ; stability ; Liapunov function ; dynamical systemSource: Springer Online Journal Archives 1860-2000Topics: MathematicsPhysicsNotes: Abstract The nonlinear equations of motion for an incompressible simple fluid, occupying a fixed bounded container, are formulated on the basis of the “finitelinear” viscoelasticity theory for materials with fading memory; this formal boundary-initial value problem is then viewed as a nonlinear abstract evolution equation on a certain Hilbert space. It is shown that a linearized version of this evolution equation is associated with a linear dynamical system on this Hilbert space, and several results for stability and asymptotic behavior for this linearized problem are proved through the use of Liapunov stability methods. On the assumption that the original nonlinear evolution equation also is associated with some dynamical system on the same space, it is shown that the rest condition of the fluid is stable and all motions are bounded. The Liapunov function employed for this purpose can be interpreted as a mechanical energy function for the fluid.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] It was noticed10 that after a molecular sieve column was heated above the normal reactivation temperature of 300 C a partial separation of argon and oxygen resulted at a column temperature of 25 C. The operating parameters for optimum separation of argon and oxygen and the constancy of resolution ...Type of Medium: Electronic ResourceURL: -
14Walker, J. A. ; Carr, M. J. ; Patino, L. C. ; Johnson, C. M. ; Feigenson, M. D. ; Ward, R. L.
Springer
Published 1995Staff ViewISSN: 1432-0967Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesNotes: Abstract. Lavas erupted behind the volcanic front in southeastern Guatemala have many important distinctions from lavas erupted on the volcanic front. These include: generally higher MgO, Nb, Sr, TiO2, and rare earth element concentrations; higher La/Yb and Nb/Y ratios; and lower Ba/La, La/Nb, Ba/Zr and Zr/Nb ratios. These major and trace element distinctions are caused by reduced fractionation during ascent and storage in the crust, lower degrees of melting in the source, and greatly reduced contributions from the subducted Cocos plate in the source. In addition, because all of these important distinctions are even borne in lavas erupted within 20 km of the front, there is little apparent petrogenetic continuity between front and behind-the-front magmas. What little geochemical continuity exists is in radiogenic isotopes: 143Nd/144Nd falls across the arc, Pb isotopic ratios (except 206Pb/204Pb) rise across the arc, and 87Sr/86Sr rise across the arc after an initial discontinuity within 20 km of the front. These continuous across-arc changes in radiogenic isotopes are caused by increased contamination with older, more isotopically disparate rocks, away from the front. Once the effects of crustal contamination are removed, the remaining isotopic variability behind the front is non-systematic and reflects the inherent isotopic heterogeneity of the source, the mantle wedge. Geochemical disconnection in southeastern Guatemala suggests that behind-the-front magmas are produced by decompression melting near the top of the wedge, not by flux-dominated melting near the base of the wedge.Type of Medium: Electronic ResourceURL: -
15Walker, J. A. ; Carr, M. J. ; Patino, L. C. ; Johnson, C. M. ; Feigenson, M. D. ; Ward, R. L.
Springer
Published 1995Staff ViewISSN: 1432-0967Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesNotes: Abstract Lavas erupted behind the volcanic front in southeastern Guatemala have many important distinctions from lavas erupted on the volcanic front. These include: generally higher MgO, Nb, Sr, TiO2, and rare earth element concentrations; higher La/Yb and Nb/Y ratios; and lower Ba/La, La/Nb, Ba/Zr and Zr/Nb ratios. These major and trace element distinctions are caused by reduced fractionation during ascent and storage in the crust, lower degrees of melting in the source, and greatly reduced contributions from the subducted Cocos plate in the source. In addition, because all of these important distinctions are even borne in lavas erupted within 20 km of the front, there is little apparent petrogenetic continuity between front and behind-the-front magmas. What little geochemical continuity exists is in radiogenic isotopes: 143Nd/144Nd falls across the arc, Pb isotopic ratios (except 206Pb/204Pb) rise across the arc, and 87Sr/86Sr rise across the arc after an initial discontinuity within 20 km of the front. These continuous across-arc changes in radiogenic isotopes are caused by increased contamination with older, more isotopically disparate rocks, away from the front. Once the effects of crustal contamination are removed, the remaining isotopic variability behind the front is non-systematic and reflects the inherent isotopic heterogeneity of the source, the mantle wedge. Geochemical disconnection in southeastern Guatemala suggests that behind-the-front magmas are produced by decompression melting near the top of the wedge, not by flux-dominated melting near the base of the wedge.Type of Medium: Electronic ResourceURL: -
16Karen Bentley, P. ; Gates, Richard M. C. ; Lowe, Kenneth C. ; Pomerai, David I. ; Lucy Walker, J. A.
Springer
Published 1989Staff ViewISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary The effects of a non-ionic surfactant, Pluronic F-68, on growth of chick embryonic fibroblasts and hamster melanoma cellsin vitro have been studied. Low concentrations (0.05–0.1% w/v) of commercial grade Pluronic stimulated growth of both cell types whereas low concentrations of purified Pluronic inhibited fibroblast growth but strongly stimulated growth of melanoma cells. These observations suggest that Pluronic may have value for regulating growth of cell cultures.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1573-2878Keywords: Extremum principles ; necessary conditions ; sufficient conditions ; optimal controls ; lumped-parameter systems ; distributed-parameter systemsSource: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Abstract Extremum principles intended for use in optimal control are derived in the form of necessary conditions and sufficient conditions, formulated in general normed linear spaces. The method of application is illustrated by several examples involving optimal control problems, mathematical programming problems, lumped-parameter systems, and distributed-parameter systems. The basic theorems provide a unified approach which is applicable to a wide variety of problems in open-loop optimal control.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1573-2878Keywords: Feedback design ; Liapunov criteria ; targeting problemsSource: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Abstract We study the problem of designing targeting-type feedback control laws for systems with state and control constraints. A systematic approach to this problem is described in terms of a number of Liapunov-like criteria. This approach is presented in tutorial form and is illustrated by means of two examples having some background in the literature.Type of Medium: Electronic ResourceURL: -
19Besseris, G. J. ; Kiefer, J. H. ; Zhang, Q. ; Walker, J. A. ; Tsang, W.
New York, NY : Wiley-Blackwell
Published 1995Staff ViewISSN: 0538-8066Keywords: Chemistry ; Physical ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The thermal decomposition of 3,4-dihydro-2H-pyran (DHP, C5H8O) has been investigated by two methods: in shock waves with the laser-schlieren technique using mixtures of 5 and 10% DHP in krypton over 900-1500 K, 110-560 torr; in a flow tube having a reaction pressure 0.5 torr above atmospheric using the decomposition of allylethyl ether as an internal standard, and covering 663-773 K. The retro-Diels-Alder dissociation to the stable acrolein and ethylene is the dominant channel for all conditions. Precise rate constants (rms deviation of 10%) were obtained for this process over the indicated temperature ranges. Unimolecular falloff is evident in the shock-tube results, and RRKM calculations also predict a slight falloff at the lower temperatures. These RRKM calculations use a routine vibration model transition state and agree closely with the high-temperature data when 〈ΔE〉down is a fixed 400 cm-1. Arrhenius expressions for k∞ derived from the two measurements are in close accord and also consistent with most previous studies of this reaction. © 1995 John Wiley & Sons, Inc.Additional Material: 5 Ill.Type of Medium: Electronic ResourceURL: -
20Sidhu, S. S. ; Kiefer, J. H. ; Lifshitz, A. ; Tamburu, C. ; Walker, J. A. ; Tsang, W.
New York, NY : Wiley-Blackwell
Published 1991Staff ViewISSN: 0538-8066Keywords: Chemistry ; Physical ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Rate constants for the retro-Diels-Alder dissociation of 1,2,3,6-tetrahydropyridine, to 1,3-butadiene and methanimine, have been measured over 650-1450 K. To cover this range, three separate techniques were used at three laboratories: laser schlieren and single pulse shock tube methods, and a comparative rate flow system technique. The derived rate constants are extrapolated to the high-pressure limit with an RRKM model parameterized to fit the falloff observed in the laser-schlieren measurements. The resulting high-pressure rate constants show a reduction in activation energy of about 10 kcal/mol, comparing the isoelectronic cyclohexene, but little change in A-factor. There is an apparent increase in activation energy of 4 kcal/mol over the temperature range of these experiments, which is just outside probable error. Such a rise in activation energy is in marked contrast to the drop usually seen in simple bond fission, and may reflect a change from a concerted to a stepwise, biradical mechanism at high temperatures.Additional Material: 8 Ill.Type of Medium: Electronic ResourceURL: