Search Results - (Author, Cooperation:J. A. Stein)
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1Latest Papers from Table of Contents or Articles in PressW. E. Feeney ; I. Medina ; M. Somveille ; R. Heinsohn ; M. L. Hall ; R. A. Mulder ; J. A. Stein ; R. M. Kilner ; N. E. Langmore
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-12-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Africa, Southern ; *Aggression ; Animal Distribution ; Animals ; Australia ; *Biological Evolution ; *Breeding ; *Cooperative Behavior ; *Nesting Behavior ; Passeriformes/classification/*physiology ; Phylogeny ; Vocalization, AnimalPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2016-05-27Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Fisheries/*legislation & jurisprudence ; *FishesPublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] In view of the profound effect of severe hyperthyroidism on tumour growth and its response to radiation, it became of interest to investigate the turnover of thyroxine in animals bearing these tumours. The rate of deiodination of thyroxine was investigated by administration of a tracer quantity of ...Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesAdler, A. ; Stein, J. A. ; Goldfarb, A. J. ; Levy, E. ; Inbar, M. ; Altboim, I. ; Rozin, R. R. ; Teva, Z. ; Czernobilsky, B.
Springer
Published 1980Staff ViewISSN: 1432-0851Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Active specific immunization with autologous irradiated tumor cells (AITC) admixed with BCG was attempted in 49 stage III breast cancer patients whose median follow-up at present is 3 years. As a first immunizing procedure 41 patients received repeated intradermal inoculations and 8 had a single endolymphatic instillation (ELI). Skin response (SR) to AITC alone was induced after two to nine weekly immunizations. Eight of 41 patients with negative or weak responses were effectively reimmunized by ELI, as indicated by conversion and invigoration of SR. Following immunization, radiotherapy to breast and axilla was administered. Thereafter, fortnightly 5-FU and monthly boosters of AITC-BCG mixture were given for 2 years. Strength of response to AITC induced by active immunization was found to relate to subsequent disease recurrence, with 15% relapsing among the good responders and 53% among the weak and non-responders. Positive SR to AITC — once elicited — was steadily maintained in the majority of patients; its decline was associated with manifest disease recurrence. Conversion to AITC positivity in vivo following specific immunization was not detectable by the LMI assay. Lymphocyte stimulation (MLTI) by AITC in vitro was found in only 9 of 26 tested patients with positive in vivo SR to AITC. Cutaneous response to AITC appears to be the only parameter of antitumor response showing clinical correlation, while specific in vitro correlates of cell-mediated immunity were found unsuitable for monitoring patients undergoing specific immunotherapy. While in vivo PPD response was mainly unchanged or enhanced, in vitro lymphocyte stimulation by PPD and PHA showed a distinct decline at the time of relapse. The cumulative proportion of relapse among the immunotherapy patients at 3 years was 32% with mortality of 12% (13 relapsed, 5 died), both being significantly lower than reported results in stage III breast cancer without immunotherapy. It is concluded that specific immunization with AITC is feasible in most breast cancer patients with loco-regionally advanced disease and that this intervention is conducive to favorable modification of the course of their disease.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStein, J. A. ; Siletzki-Ciechanover, M. ; Gefel, A. ; Adler, A. ; Michaeli, D.
Springer
Published 1978Staff ViewISSN: 1432-0851Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesEl-Khatib, O. S. ; Lebwohl, O. ; Attia, A. A. ; Flood, C. A. ; Stein, J. A. ; Sweeting, J. G. ; Whitlock, R. T. ; Osserman, E. F. ; Holt, P. R.
Springer
Published 1978Staff ViewISSN: 1573-2568Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The serum levels of lysozyme, serum electrophoresis, and serum immunoglobulins were determined prospectively in 101 patients with ulcerative colitis, ulcerative proctitis, Crohn's disease, or nonclassifiable nonspecific inflammatory bowel disease. Although the mean serum lysozyme concentration of patients with Crohn's disease (10.5±6.8 μg/ml) and ulcerative colitis (9.6±4.1 μg/ml) performed by a standardized lysoplate method was significantly greater than normal controls (6.0±1.5 μg/ml), the results did not correlate with the diagnosis nor with the degree of disease activity. Individually separated protein fractions and serum immunoglobulins also did not correlate with the serum lysozyme levels. This study indicates that measurement of the level of serum lysozyme in individual patients is not helpful in determining the cause or degree of activity of non-specific inflammatory bowel disease.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesImhof, W. L. ; Spear, K. A. ; Hamilton, J. W. ; Higgins, B. R. ; Murphy, M. J. ; Pronko, J. G. ; Vondrak, R. R. ; McKenzie, D. L. ; Rice, C. J. ; Gorney, D. J. ; Roux, D. A. ; Williams, R. L. ; Stein, J. A. ; Bjordal, J. ; Stadsnes, J. ; Njoten, K. ; Rosenberg, T. J. ; Lutz, L. ; Detrick, D.
Springer
Published 1995Staff ViewISSN: 1572-9672Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The Polar Ionospheric X-ray Imaging Experiment (PIXIE) is an X-ray multiple-pinhole camera designed to image simultaneously an entire auroral region from high altitudes. It will be mounted on the despun platform of the POLAR spacecraft and will measure the spatial distribution and temporal variation of auroral X-ray emissions in the 2 to 60 keV energy range on the day side of the Earth as well as the night. PIXIE consists of two pinhole cameras integrated into one assembly, each equipped with an adjustable aperture plate that allows an optimum number of nonoverlapping images to be formed in the detector plane at each phase of the satellite's eccentric orbit. The aperture plates also allow the pinhole size to be adjusted so that the experimenter can trade off spatial resolution against instrument sensitivity. In the principal mode of operation, one aperture plate will be positioned for high spatial resolution and the other for high sensitivity. The detectors consist of four stacked multiwire position-sensitive proportional counters, two in each of two separate gas chambers. The front chamber operates in the 2–12 keV energy range and the rear chamber in the 10–60 keV range. All of the energy and position information for each telemetered X-ray event is available on the ground. This enables the experimenter to adjust the exposure timepostfacto so that energy spectra of each X-ray emitting region can be independently accumulated. From these data PIXIE will provide, for the first time, global images of precipitated energetic electron spectra, energy inputs, ionospheric electron densities, and upper atmospheric conductivities.Type of Medium: Electronic ResourceURL: