Search Results - (Author, Cooperation:I. Barber)
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1Latest Papers from Table of Contents or Articles in PressC. Cruchaga ; C. M. Karch ; S. C. Jin ; B. A. Benitez ; Y. Cai ; R. Guerreiro ; O. Harari ; J. Norton ; J. Budde ; S. Bertelsen ; A. T. Jeng ; B. Cooper ; T. Skorupa ; D. Carrell ; D. Levitch ; S. Hsu ; J. Choi ; M. Ryten ; J. Hardy ; D. Trabzuni ; M. E. Weale ; A. Ramasamy ; C. Smith ; C. Sassi ; J. Bras ; J. R. Gibbs ; D. G. Hernandez ; M. K. Lupton ; J. Powell ; P. Forabosco ; P. G. Ridge ; C. D. Corcoran ; J. T. Tschanz ; M. C. Norton ; R. G. Munger ; C. Schmutz ; M. Leary ; F. Y. Demirci ; M. N. Bamne ; X. Wang ; O. L. Lopez ; M. Ganguli ; C. Medway ; J. Turton ; J. Lord ; A. Braae ; I. Barber ; K. Brown ; P. Passmore ; D. Craig ; J. Johnston ; B. McGuinness ; S. Todd ; R. Heun ; H. Kolsch ; P. G. Kehoe ; N. M. Hooper ; E. R. Vardy ; D. M. Mann ; S. Pickering-Brown ; N. Kalsheker ; J. Lowe ; K. Morgan ; A. David Smith ; G. Wilcock ; D. Warden ; C. Holmes ; P. Pastor ; O. Lorenzo-Betancor ; Z. Brkanac ; E. Scott ; E. Topol ; E. Rogaeva ; A. B. Singleton ; M. I. Kamboh ; P. St George-Hyslop ; N. Cairns ; J. C. Morris ; J. S. Kauwe ; A. M. Goate
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-12-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: African Americans/genetics ; Age of Onset ; Aged ; Aged, 80 and over ; Alzheimer Disease/*genetics/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Brain/metabolism ; Case-Control Studies ; Europe/ethnology ; Exome/genetics ; Female ; Genetic Predisposition to Disease/*genetics ; Genetic Variation/*genetics ; Humans ; Male ; Peptide Fragments/metabolism ; Phospholipase D/deficiency/*genetics/metabolism ; Protein Processing, Post-Translational/genetics ; ProteolysisPublished by: -
2Articles: DFG German National LicensesBarber, I. ; Young, J. ; Morrison-Smith, E. ; Matthews, E.
Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc
Published 2003Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Teleost fish are commonly used as model species in laboratory studies of behaviour and ecology. In comparison to other groups of vertebrates used routinely in such studies, however, relatively little attention has been paid to their environmental requirements from a welfare perspective. Fish naturally inhabit a wide variety of aquatic habitats that differ enormously in the range of light environments they provide, and light regime has enormous potential to affect behaviour. Yet the level and quality of illumination (in terms of intensity and wavelength spectrum) provided in experimental studies of fish behaviour is generally designed to maximize ease of recording by the observer. In addition, display or home aquaria provide illumination that maximizes the ‘viewing pleasure’ of the observer, and specialist lighting tubes are available to stimulate rapid plant growth and to ‘show off’ the colours of fish, rather than to provide ‘natural’ light environments. Here we present the results of three studies designed to examine the effects of light intensity, wavelength spectrum and their interactions on the behaviour of a model species commonly used in behavioural studies, the three-spined stickleback Gasterosteus aculeatus. Our aims are to determine whether unnatural light environments, generated by manipulating light intensity and wavelength spectrum, affect behaviour in ways that may lead to concern for the welfare of fish as research animals or pets.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Many parasites rely on the predation of one host by another to be transmitted. Such parasites are expected to have evolved strategies of host manipulation that alter the susceptibility of current hosts to predation by suitable predators, and many examples of altered behaviour exist. For many parasites, however, a period of growth and development in each host is essential before they are ready to be transmitted. If changes in host behaviour are truly parasite adaptations, rather than side-effects of infection, then host behaviour change should only be predicted when the parasite is infective to the next host. This study documents the behaviour of individual three spined sticklebacks Gasterosteus aculeatus over a 16-week period following experimental infection with the common cestode parasite Schistocephalus solidus, which requires infected fish to be ingested by birds before it can attain sexual maturity. In addition to regularly monitoring shelter use and escape response behaviour of infected fish, we also used non-invasive morphometric techniques to estimate parasite size, and thus were able to link behaviour changes to the growth of the parasite in individual fish. The behaviour of experimentally infected sticklebacks deviated significantly from that of controls (sham-exposed) fish when the parasites they harboured approached an estimated weight of 100 mg. The results are discussed in the light of a further study, examining the relationship between parasite size and ultimate fecundity in the bird host.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesArnold, K. E. ; Adam, A. ; Orr, K. J. ; Griffiths, R. ; Barber, I.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: A molecular method of identifying sex in three-spined sticklebacks Gasterosteus aculeatus showed that adult males had a higher prevalence of dermal Glugea anomala cysts than adult females, and young-of-the-year had more than adults. At the end of the breeding season, as predicted, the adult sex ratio became female biased and there was a disproportionate increase in G. anomala parasitism in adult males.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Naturally formed shoals of adult Gobiusculus flavescens in a Swedish fjord ranged in size from a few individuals to several hundred fish and were sorted by body size. Shoal composition was highly dynamic and any particular group was unlikely to remain together for more than a few hours. Shoaling tendency of juveniles in laboratory experiments was high, and consistent preferences were demonstrated for numerically larger shoals. Large test fish preferred to associate with shoals composed of large, over shoals composed of small fish, whereas small test fish associated with both size classes equally. The ecological importance of shoaling in small shallow water fish is discussed, and possible mechanisms for the observed patterns are proposed.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: A non-invasive morphometric technique is presented which can be used to predict the infection status and the proportion of infected fish weight contributed by parasite tissue in three-spined sticklebacks Gasterosteus aculeatus infected with plerocercoids of Schistocephalus solidus (Cestoda: Pseudophyllidea)Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesWright, H. A. ; Wootton, R. J. ; Barber, I.
Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc
Published 2003Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Three-spined sticklebacks (Gasterosteus aculeatus) exhibit considerable inter-population variation in behaviour, morphology and life history characteristics. Such population-level variation can be generated directly by environmental characteristics of the water body they inhabit (e.g. temperature regimes, which directly influence growth rates) but local genetic adaptation is also important. By performing ‘common garden’ experiments, in which laboratory-bred individuals from separate populations are raised under standardized controlled laboratory conditions, it is possible to identify genetically-based population-level phenotype variation. Here we present the results of two studies, carried out using juvenile three-spined sticklebacks bred from parental stock from five geographically isolated UK populations and reared under standard laboratory (‘common garden’) conditions. Firstly we report the results of a study examining population-level variation in patterns of early growth, in which we tracked the growth of replicate groups of full-sibs from all five populations, from hatching to 126d. Secondly we report the results of an experimental behavioural study, designed to examine population-level variation in the exploratory or ‘boldness’ behaviour of laboratory-bred and reared juvenile three-spined sticklebacks from the same five populations. We discuss how adaptive genetically based patterns of behaviour and growth may co-vary across populations.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesGriffiths, R. ; Orr, K. L. ; Adam, A. ; Barber, I.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Two sex linked DNA markers are isolated in the three-spined stickleback Gasterosteus aculeatus and a sex identification test is developed.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesBarber, I. ; Arnott, S. A. ; Braithwaite, V. A. ; Andrew, J. ; Mullen, W. ; Huntingford, F. A.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The extent, corrected for body size, and intensity of nuptial coloration of breeding male three-spined sticklebacks Gasterosteus aculeatus L. from a Scottish freshwater population were highly variable but correlated, both in the field and after a period of nest-building in the laboratory. However, marked changes in coloration occurred between the field and the laboratory screenings and the coefficients of variation amongst males decreased. In general, intensity of coloration increased between the field and laboratory screenings, but changes in size-corrected extent were not consistently directional. For both indices, there was a negative relationship between the field value and amount by which colour changed between sampling sessions, with fish that were initially the dullest gaining most in colour. Size-corrected extent and (in particular) intensity of coloration in the field sample were associated positively with body condition measured post mortem and there was a negative, though non-significant, relationship between the extent of coloration and the proportion of white cells in the blood. No such associations were found for the laboratory colour screening. The concentration of astaxanthin in the lower jaw was related strongly and positively to both size-corrected extent and intensity of coloration at the laboratory screening and related negatively, though non-significantly, to proportional white cell counts. These data have implications both for the interpretation of previous laboratory studies and for the design of future experiments, and suggest that coloration is only a true indicator of male quality when measured in the field.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesBarber, I. ; Downey, L. C. ; Braithwaite, V. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1998Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: When choosing between shoals differing in Schistocephalus solidus infection status, uninfected test sticklebacks Gasterosteus aculeatus showed a preference for joining uninfected conspecifics when shoal sizes were equal, but reversed this preference when the relative size of the infected shoal was increased by a factor of 3. When given a choice between a shoal composed of size-matched minnows Phoxinus phoxinus and a shoal composed of the same number of all uninfected or all S. solidus-infected sticklebacks, test fish always preferred the sticklebacks, regardless of their infection status, over the minnow shoal. These observations suggest that species, parasite status and shoal size are all of importance when fish decide which shoal to join.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Experiments have shown thai infection by low intensities of the eye fluke affects the vision of three-spined stickleback when selecting prey, and also shortens the reactive distance to the prey. The results have consequences for the fitness of the individual, and also for the study of prey selection.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Male sand goby Pomatoschistus minutus dominance in competition over nest sites was associated with higher body condition but not with the intensity of infection with any individual parasite of six different species, nor with an overall index combining relative levels of infection by all parasites. Body condition was not related to the intensity of infection with any individual parasite nor with the index of total relative parasite load. In trials in which females spawned, they showed a tendency to choose dominant over subordinate males as mates, but did not consistently choose less parasitized males. Variation in the relative size of the dorsal fins of males was detected, and this related to numbers of the ectoparasitic monogenean Gyrodactylus sp., suggesting that at least some infections have phenotypic effects that could allow females to detect and avoid the most heavily infected males.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesPerigaud, C. ; Gosselin, G. ; Lefebvre, I. ; Girardet, J.-L. ; Benzaria, S. ; Barber, I. ; Imbach, J.-L.
Amsterdam : ElsevierStaff ViewISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0166-445XKeywords: Cadmium ; Daphnia ; SDASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesPruna, X. ; Ibañez, J. M. ; Serres, X. ; Garriga, V. ; Barber, I. ; Vera, J.
Springer
Published 2000Staff ViewISSN: 1432-1084Keywords: Key words: CT ; Antrochoanal polyp ; Pediatric populationSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract. Antrochoanal polyp (Killian polyp) is an infrequent, usually solitary, benign, slowly growing lesion that arises from the maxillary antrum and reaches the choana. These polyps have a discrete male predominance and are diagnosed usually between the third and the fifth decades of life. This report is based on three cases of antrochoanal polyp, occurring in the pediatric group, and the objective is to demonstrate their different CT characteristics, principal differential diagnoses, and potential complications. We emphasize that in all three cases of our series the growth of the polyp to the choana is through the accessory ostium.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesLimitations to colour-based sexual preferences in three-spined sticklebacks (Gasterosteus aculeatus)Staff View
ISSN: 1432-0762Keywords: Key words Sexual selection ; Stickleback ; Nuptial coloration ; Gasterosteus aculeatus ; CarotenoidsSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Female three-spined sticklebacks (Gasterosteus aculeatus) are suggested to select mates based on their red nuptial coloration, males with a redder display being more preferred. Although there are both laboratory and field data to support this view, there are also published accounts where females do not show a preference for the redder male. Here we report the results of a series of 19 trials where receptive gravid female three-spined sticklebacks were allowed to choose between two size-matched rival males. We used photographic and image analysis techniques to quantify male nuptial coloration to investigate how the magnitude of the colour difference between the two alternative males influenced female preferences. Using the amount of time a female spent oriented towards each male as a measure of his attractiveness to her, females were not always found to select the redder of the two presented males. We did, however, find that that the relative difference in coloration of the two males in each pair was important in determining the level of coloration-based preference, with females only selecting redder males consistently when the difference in coloration was sufficiently large.Type of Medium: Electronic ResourceURL: