ILSE | Search Results - (Author, Cooperation:I. A. Wilson)

1

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

N. A. Doria-Rose ; C. A. Schramm ; J. Gorman ; P. L. Moore ; J. N. Bhiman ; B. J. DeKosky ; M. J. Ernandes ; I. S. Georgiev ; H. J. Kim ; M. Pancera ; R. P. Staupe ; H. R. Altae-Tran ; R. T. Bailer ; E. T. Crooks ; A. Cupo ; A. Druz ; N. J. Garrett ; K. H. Hoi ; R. Kong ; M. K. Louder ; N. S. Longo ; K. McKee ; M. Nonyane ; S. O'Dell ; R. S. Roark ; R. S. Rudicell ; S. D. Schmidt ; D. J. Sheward ; C. Soto ; C. K. Wibmer ; Y. Yang ; Z. Zhang ; J. C. Mullikin ; J. M. Binley ; R. W. Sanders ; I. A. Wilson ; J. P. Moore ; A. B. Ward ; G. Georgiou ; C. Williamson ; S. S. Abdool Karim ; L. Morris ; P. D. Kwong ; L. Shapiro ; J. R. Mascola
Nature Publishing Group (NPG)
Published 2014

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Publication Date:	2014-03-05
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/chemistry/immunology ; Amino Acid Sequence ; Antibodies, Neutralizing/chemistry/genetics/immunology/isolation & purification ; Antibody Affinity/genetics/immunology ; Antigens, CD4/immunology/metabolism ; B-Lymphocytes/cytology/immunology/metabolism ; Binding Sites/immunology ; Cell Lineage ; Complementarity Determining Regions/chemistry/genetics/immunology ; Epitope Mapping ; Epitopes, B-Lymphocyte/chemistry/immunology ; Evolution, Molecular ; HIV Antibodies/chemistry/genetics/immunology/isolation & purification ; HIV Envelope Protein gp160/chemistry/immunology ; HIV Infections/immunology ; HIV-1/chemistry/immunology ; Humans ; Models, Molecular ; Molecular Sequence Data ; Neutralization Tests ; Protein Structure, Tertiary ; Somatic Hypermutation, Immunoglobulin/genetics
Published by:	http://www.nature.com/

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2

Computational design of proteins targeting the conserved stem region of influenza hemagglutinin

S. J. Fleishman ; T. A. Whitehead ; D. C. Ekiert ; C. Dreyfus ; J. E. Corn ; E. M. Strauch ; I. A. Wilson ; D. Baker
American Association for the Advancement of Science (AAAS)
Published 2011

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Publication Date:	2011-05-14
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Algorithms ; Amino Acid Sequence ; Binding Sites ; Computational Biology ; Computer Simulation ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry/metabolism ; Hydrogen Bonding ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Peptide Library ; Protein Binding ; Protein Conformation ; Protein Engineering ; Protein Interaction Domains and Motifs ; Protein Structure, Secondary ; Proteins/chemistry/genetics/metabolism ; Software
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

3

A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis

G. Bhabha ; J. Lee ; D. C. Ekiert ; J. Gam ; I. A. Wilson ; H. J. Dyson ; S. J. Benkovic ; P. E. Wright
American Association for the Advancement of Science (AAAS)
Published 2011

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Publication Date:	2011-04-09
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Biocatalysis ; Catalytic Domain ; Crystallography, X-Ray ; Escherichia coli/enzymology ; Folic Acid/chemistry ; Kinetics ; Models, Molecular ; Molecular Sequence Data ; Mutant Proteins/chemistry/metabolism ; NADP/chemistry ; Protein Conformation ; Tetrahydrofolate Dehydrogenase/chemistry/genetics/*metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

4

Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses

D. R. Burton ; P. Poignard ; R. L. Stanfield ; I. A. Wilson
American Association for the Advancement of Science (AAAS)
Published 2012

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Publication Date:	2012-07-17
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/immunology ; Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Antigenic Variation ; Drug Discovery ; HIV Antibodies/chemistry/immunology ; HIV Infections/immunology/prevention & control ; HIV-1/immunology/pathogenicity ; Hepacivirus/immunology ; Hepatitis C/immunology/prevention & control ; Humans ; Influenza Vaccines ; Influenza, Human/immunology/prevention & control ; Models, Molecular ; Orthomyxoviridae/*immunology ; env Gene Products, Human Immunodeficiency Virus/chemistry/immunology
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

5

Highly conserved protective epitopes on influenza B viruses

C. Dreyfus ; N. S. Laursen ; T. Kwaks ; D. Zuijdgeest ; R. Khayat ; D. C. Ekiert ; J. H. Lee ; Z. Metlagel ; M. V. Bujny ; M. Jongeneelen ; R. van der Vlugt ; M. Lamrani ; H. J. Korse ; E. Geelen ; O. Sahin ; M. Sieuwerts ; J. P. Brakenhoff ; R. Vogels ; O. T. Li ; L. L. Poon ; M. Peiris ; W. Koudstaal ; A. B. Ward ; I. A. Wilson ; J. Goudsmit ; R. H. Friesen
American Association for the Advancement of Science (AAAS)
Published 2012

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Publication Date:	2012-08-11
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Animals ; Antibodies, Monoclonal/chemistry/immunology ; Antibodies, Neutralizing/chemistry/immunology ; Conserved Sequence ; Hemagglutinin Glycoproteins, Influenza Virus/immunology ; Humans ; Immunodominant Epitopes/chemistry/immunology ; Influenza B virus/immunology ; Influenza Vaccines/immunology ; Mice ; Molecular Sequence Data ; Neutralization Tests ; Orthomyxoviridae Infections/prevention & control ; Protein Conformation
Published by:	http://www.aaas.org/

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6

A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield

R. Pejchal ; K. J. Doores ; L. M. Walker ; R. Khayat ; P. S. Huang ; S. K. Wang ; R. L. Stanfield ; J. P. Julien ; A. Ramos ; M. Crispin ; R. Depetris ; U. Katpally ; A. Marozsan ; A. Cupo ; S. Maloveste ; Y. Liu ; R. McBride ; Y. Ito ; R. W. Sanders ; C. Ogohara ; J. C. Paulson ; T. Feizi ; C. N. Scanlan ; C. H. Wong ; J. P. Moore ; W. C. Olson ; A. B. Ward ; P. Poignard ; W. R. Schief ; D. R. Burton ; I. A. Wilson
American Association for the Advancement of Science (AAAS)
Published 2011

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Publication Date:	2011-10-15
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Antibodies, Neutralizing/chemistry/genetics/immunology/metabolism ; Antibody Specificity ; Binding Sites, Antibody ; Carbohydrate Conformation ; Cell Line ; Crystallography, X-Ray ; Disaccharides/chemistry/metabolism ; Epitopes ; Glycosylation ; HIV Antibodies/chemistry/genetics/immunology/metabolism ; HIV Envelope Protein gp120/chemistry/immunology/metabolism ; HIV-1/immunology/physiology ; Humans ; Hydrogen Bonding ; Immunoglobulin Fab Fragments/chemistry/immunology/metabolism ; Mannose/chemistry/immunology/metabolism ; Mannosides/chemistry/metabolism ; Models, Molecular ; Mutation ; Oligosaccharides/chemistry/immunology/metabolism ; Polysaccharides/chemistry/immunology/metabolism ; Protein Conformation ; Protein Structure, Tertiary
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

7

Structural basis of steroid hormone perception by the receptor kinase BRI1

M. Hothorn ; Y. Belkhadir ; M. Dreux ; T. Dabi ; J. P. Noel ; I. A. Wilson ; J. Chory
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-06-15
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Arabidopsis/chemistry/metabolism ; Arabidopsis Proteins/chemistry/metabolism ; Binding Sites ; Brassinosteroids ; Cholestanols/chemistry/metabolism ; Crystallography, X-Ray ; Enzyme Activation ; Models, Molecular ; Molecular Sequence Data ; Plant Growth Regulators/chemistry/metabolism ; Protein Binding ; Protein Kinases/chemistry/metabolism ; Protein Multimerization ; Protein Structure, Tertiary ; Steroids, Heterocyclic/chemistry/metabolism ; Structure-Activity Relationship
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

8

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

J. S. McLellan ; M. Pancera ; C. Carrico ; J. Gorman ; J. P. Julien ; R. Khayat ; R. Louder ; R. Pejchal ; M. Sastry ; K. Dai ; S. O'Dell ; N. Patel ; S. Shahzad-ul-Hussan ; Y. Yang ; B. Zhang ; T. Zhou ; J. Zhu ; J. C. Boyington ; G. Y. Chuang ; D. Diwanji ; I. Georgiev ; Y. D. Kwon ; D. Lee ; M. K. Louder ; S. Moquin ; S. D. Schmidt ; Z. Y. Yang ; M. Bonsignori ; J. A. Crump ; S. H. Kapiga ; N. E. Sam ; B. F. Haynes ; D. R. Burton ; W. C. Koff ; L. M. Walker ; S. Phogat ; R. Wyatt ; J. Orwenyo ; L. X. Wang ; J. Arthos ; C. A. Bewley ; J. R. Mascola ; G. J. Nabel ; W. R. Schief ; A. B. Ward ; I. A. Wilson ; P. D. Kwong
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-11-25
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/chemistry/immunology ; Amino Acid Motifs ; Amino Acid Sequence ; Antibodies, Neutralizing/chemistry/immunology ; Antibody Affinity/immunology ; Antibody Specificity/immunology ; Antigen-Antibody Complex/chemistry/immunology ; Binding Sites, Antibody/immunology ; Conserved Sequence ; Crystallography, X-Ray ; Epitopes/chemistry/immunology ; Glycopeptides/chemistry/immunology ; Glycosylation ; HIV Antibodies/chemistry/immunology ; HIV Envelope Protein gp120/chemistry/immunology ; HIV-1/chemistry/*immunology ; Hydrogen Bonding ; Immune Evasion ; Models, Molecular ; Molecular Sequence Data ; Polysaccharides/chemistry/immunology ; Protein Structure, Quaternary ; Protein Structure, Tertiary
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

9

Broad neutralization coverage of HIV by multiple highly potent antibodies

L. M. Walker ; M. Huber ; K. J. Doores ; E. Falkowska ; R. Pejchal ; J. P. Julien ; S. K. Wang ; A. Ramos ; P. Y. Chan-Hui ; M. Moyle ; J. L. Mitcham ; P. W. Hammond ; O. A. Olsen ; P. Phung ; S. Fling ; C. H. Wong ; S. Phogat ; T. Wrin ; M. D. Simek ; W. C. Koff ; I. A. Wilson ; D. R. Burton ; P. Poignard
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-08-19
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/biosynthesis/immunology ; Antibodies, Monoclonal/immunology ; Antibodies, Neutralizing/immunology ; Cell Line ; Epitope Mapping ; Epitopes/chemistry/immunology ; Glycoproteins/chemistry/immunology ; Glycosylation ; HEK293 Cells ; HIV/classification/immunology/isolation & purification ; HIV Antibodies/immunology ; HIV Infections/immunology/therapy ; Human Immunodeficiency Virus Proteins/chemistry/immunology ; Humans ; Immune Sera/blood/immunology ; Molecular Sequence Data ; Neutralization Tests
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

10

Cross-neutralization of influenza A viruses mediated by a single antibody loop

D. C. Ekiert ; A. K. Kashyap ; J. Steel ; A. Rubrum ; G. Bhabha ; R. Khayat ; J. H. Lee ; M. A. Dillon ; R. E. O'Neil ; A. M. Faynboym ; M. Horowitz ; L. Horowitz ; A. B. Ward ; P. Palese ; R. Webby ; R. A. Lerner ; R. R. Bhatt ; I. A. Wilson
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-09-18
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Animals ; Antibodies, Neutralizing/chemistry/genetics/immunology ; Antibodies, Viral/chemistry/genetics/immunology ; Antibody Specificity/genetics/immunology ; Antigens, Viral/chemistry/immunology ; Binding Sites ; Complementarity Determining Regions/chemistry/genetics/immunology ; Conserved Sequence ; Cross Reactions/genetics/immunology ; Crystallography, X-Ray ; Enzyme-Linked Immunosorbent Assay ; Epitopes/chemistry/immunology ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry/immunology ; Influenza A Virus, H1N1 Subtype/chemistry/immunology ; Influenza A Virus, H3N2 Subtype/chemistry/immunology ; Influenza A virus/chemistry/classification/*immunology ; Influenza Vaccines/immunology ; Mice ; Models, Molecular ; Molecular Sequence Data ; Mutation/genetics ; Orthomyxoviridae Infections/immunology/prevention & control/virology ; Protein Conformation
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

11

A highly conserved neutralizing epitope on group 2 influenza A viruses

D. C. Ekiert ; R. H. Friesen ; G. Bhabha ; T. Kwaks ; M. Jongeneelen ; W. Yu ; C. Ophorst ; F. Cox ; H. J. Korse ; B. Brandenburg ; R. Vogels ; J. P. Brakenhoff ; R. Kompier ; M. H. Koldijk ; L. A. Cornelissen ; L. L. Poon ; M. Peiris ; W. Koudstaal ; I. A. Wilson ; J. Goudsmit
American Association for the Advancement of Science (AAAS)
Published 2011

Staff View

Publication Date:	2011-07-09
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Animals ; Antibodies, Monoclonal/immunology/isolation & purification ; Antibodies, Neutralizing/immunology/isolation & purification ; Antibodies, Viral/immunology/isolation & purification ; Antibody Specificity ; Antigens, Viral/chemistry/genetics/immunology ; Binding Sites, Antibody ; Conserved Sequence ; Crystallography, X-Ray ; Epitopes/immunology ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry/genetics/immunology ; Humans ; Influenza A Virus, H3N2 Subtype/immunology ; Influenza A Virus, H7N7 Subtype/genetics/immunology ; Influenza A virus/immunology ; Influenza Vaccines/immunology ; Influenza, Human/immunology/prevention & control/therapy ; Mice ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Neutralization Tests ; Orthomyxoviridae Infections/immunology/prevention & control ; Protein Conformation
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

12

Rational HIV immunogen design to target specific germline B cell receptors

J. Jardine ; J. P. Julien ; S. Menis ; T. Ota ; O. Kalyuzhniy ; A. McGuire ; D. Sok ; P. S. Huang ; S. MacPherson ; M. Jones ; T. Nieusma ; J. Mathison ; D. Baker ; A. B. Ward ; D. R. Burton ; L. Stamatatos ; D. Nemazee ; I. A. Wilson ; W. R. Schief
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-03-30
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/chemistry/genetics/immunology ; Amino Acid Sequence ; Animals ; Antibodies, Neutralizing/immunology ; Antigens, CD4/immunology ; B-Lymphocytes/immunology ; Crystallography, X-Ray ; DNA Mutational Analysis ; Germ Cells/immunology ; HIV Envelope Protein gp120/chemistry/genetics/immunology ; HIV Infections/prevention & control ; HIV-1/immunology ; Humans ; Macaca ; Mice ; Models, Animal ; Molecular Sequence Data ; Nanoparticles ; Protein Engineering ; Protein Structure, Tertiary ; Receptors, Antigen, B-Cell/immunology
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

13

Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer

D. Lyumkis ; J. P. Julien ; N. de Val ; A. Cupo ; C. S. Potter ; P. J. Klasse ; D. R. Burton ; R. W. Sanders ; J. P. Moore ; B. Carragher ; I. A. Wilson ; A. B. Ward
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-11-02
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/chemistry/immunology ; Antibodies, Neutralizing/chemistry ; Antibodies, Viral/chemistry ; Antigens, CD4/chemistry/immunology ; Binding Sites ; Cryoelectron Microscopy ; Glycosylation ; Immunodominant Epitopes/chemistry/immunology ; Models, Molecular ; Polysaccharides/chemistry ; Protein Multimerization ; Protein Structure, Quaternary ; Protein Structure, Tertiary ; env Gene Products, Human Immunodeficiency Virus/*chemistry/immunology
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

14

Preferential recognition of avian-like receptors in human influenza A H7N9 viruses

R. Xu ; R. P. de Vries ; X. Zhu ; C. M. Nycholat ; R. McBride ; W. Yu ; J. C. Paulson ; I. A. Wilson
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-12-07
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Animals ; Binding Sites ; Birds ; Carbohydrate Conformation ; Crystallography, X-Ray ; Hemagglutinin Glycoproteins, Influenza Virus/chemistry/metabolism ; Humans ; Influenza A Virus, H7N9 Subtype/metabolism/pathogenicity ; Influenza in Birds/transmission/virology ; Influenza, Human/transmission/virology ; Ligands ; Microarray Analysis ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Polysaccharides/chemistry/metabolism ; Receptors, Virus/chemistry/metabolism ; Recombinant Proteins/chemistry/metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

15

Hepatitis C virus E2 envelope glycoprotein core structure

L. Kong ; E. Giang ; T. Nieusma ; R. U. Kadam ; K. E. Cogburn ; Y. Hua ; X. Dai ; R. L. Stanfield ; D. R. Burton ; A. B. Ward ; I. A. Wilson ; M. Law
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-11-30
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Antibodies, Neutralizing/chemistry ; Antigens, CD81/chemistry ; Antiviral Agents/chemistry ; Binding Sites ; Crystallography, X-Ray ; Drug Design ; Epitopes/chemistry/genetics ; Humans ; Immunoglobulin Fab Fragments/chemistry ; Mutagenesis, Site-Directed ; Protein Folding ; Protein Structure, Tertiary ; Viral Envelope Proteins/*chemistry/immunology ; Viral Hepatitis Vaccines/chemistry/immunology
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

16

Complement is activated by IgG hexamers assembled at the cell surface

C. A. Diebolder ; F. J. Beurskens ; R. N. de Jong ; R. I. Koning ; K. Strumane ; M. A. Lindorfer ; M. Voorhorst ; D. Ugurlar ; S. Rosati ; A. J. Heck ; J. G. van de Winkel ; I. A. Wilson ; A. J. Koster ; R. P. Taylor ; E. O. Saphire ; D. R. Burton ; J. Schuurman ; P. Gros ; P. W. Parren
American Association for the Advancement of Science (AAAS)
Published 2014

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Publication Date:	2014-03-15
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Cell Membrane/immunology ; Complement Activation ; Complement C1/immunology ; Humans ; Immunoglobulin Fab Fragments/chemistry/immunology ; Immunoglobulin G/chemistry/immunology ; Liposomes ; Protein Conformation ; Protein Multimerization
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

17

Mechanism of activation of protein kinase JAK2 by the growth hormone receptor

A. J. Brooks ; W. Dai ; M. L. O'Mara ; D. Abankwa ; Y. Chhabra ; R. A. Pelekanos ; O. Gardon ; K. A. Tunny ; K. M. Blucher ; C. J. Morton ; M. W. Parker ; E. Sierecki ; Y. Gambin ; G. A. Gomez ; K. Alexandrov ; I. A. Wilson ; M. Doxastakis ; A. E. Mark ; M. J. Waters
American Association for the Advancement of Science (AAAS)
Published 2014

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Publication Date:	2014-05-17
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Motifs ; Amino Acid Sequence ; Cysteine/chemistry ; Enzyme Activation ; HEK293 Cells ; Humans ; Janus Kinase 2/antagonists & inhibitors/chemistry/metabolism ; Models, Molecular ; Molecular Sequence Data ; Mutation ; Protein Multimerization ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Receptors, Somatotropin/chemistry/genetics/metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

18

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

R. W. Sanders ; M. J. van Gils ; R. Derking ; D. Sok ; T. J. Ketas ; J. A. Burger ; G. Ozorowski ; A. Cupo ; C. Simonich ; L. Goo ; H. Arendt ; H. J. Kim ; J. H. Lee ; P. Pugach ; M. Williams ; G. Debnath ; B. Moldt ; M. J. van Breemen ; G. Isik ; M. Medina-Ramirez ; J. W. Back ; W. C. Koff ; J. P. Julien ; E. G. Rakasz ; M. S. Seaman ; M. Guttman ; K. K. Lee ; P. J. Klasse ; C. LaBranche ; W. R. Schief ; I. A. Wilson ; J. Overbaugh ; D. R. Burton ; A. B. Ward ; D. C. Montefiori ; H. Dean ; J. P. Moore
American Association for the Advancement of Science (AAAS)
Published 2015

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Publication Date:	2015-06-20
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/immunology ; Animals ; Antibodies, Neutralizing/immunology ; Cross Reactions ; Epitopes/immunology ; HIV Antibodies/immunology ; HIV Infections/prevention & control ; HIV-1/immunology ; Humans ; Macaca ; Protein Engineering ; Protein Multimerization ; Rabbits ; Recombinant Proteins/chemistry/genetics/immunology ; env Gene Products, Human Immunodeficiency Virus/chemistry/genetics/immunology
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

19

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

J. G. Jardine ; D. W. Kulp ; C. Havenar-Daughton ; A. Sarkar ; B. Briney ; D. Sok ; F. Sesterhenn ; J. Ereno-Orbea ; O. Kalyuzhniy ; I. Deresa ; X. Hu ; S. Spencer ; M. Jones ; E. Georgeson ; Y. Adachi ; M. Kubitz ; A. C. deCamp ; J. P. Julien ; I. A. Wilson ; D. R. Burton ; S. Crotty ; W. R. Schief
American Association for the Advancement of Science (AAAS)
Published 2016

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Publication Date:	2016-03-26
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	AIDS Vaccines/immunology ; Amino Acid Sequence ; Antibodies, Monoclonal/chemistry/immunology/isolation & purification ; Antibodies, Neutralizing/chemistry/immunology/isolation & purification ; Antibody Affinity ; B-Lymphocytes/immunology ; Cell Separation ; Combinatorial Chemistry Techniques ; Epitopes, B-Lymphocyte/chemistry/genetics/immunology ; Germ Cells/immunology ; HIV Antibodies/chemistry/immunology/isolation & purification ; HIV-1/immunology ; Humans ; Molecular Sequence Data ; Mutation ; Peptide Library ; Precursor Cells, B-Lymphoid/immunology ; Protein Conformation
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

20

Structural basis of TLR5-flagellin recognition and signaling

S. I. Yoon ; O. Kurnasov ; V. Natarajan ; M. Hong ; A. V. Gudkov ; A. L. Osterman ; I. A. Wilson
American Association for the Advancement of Science (AAAS)
Published 2012

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Publication Date:	2012-02-22
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Animals ; Crystallography, X-Ray ; Dimerization ; Flagellin/chemistry/metabolism ; Models, Molecular ; Mutagenesis ; Protein Conformation ; Salmonella enterica ; Signal Transduction ; Structure-Activity Relationship ; Toll-Like Receptor 5/chemistry/genetics/metabolism ; Zebrafish ; Zebrafish Proteins/chemistry/genetics/metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

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