Search Results - (Author, Cooperation:Habs)
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1Articles: DFG German National LicensesStaff View
ISSN: 1432-1335Keywords: Di(N-nitroso)perhydropyrimidine ; Carcinogenicity in rats ; Squamous-cell carcinomas of the paranasal sinusSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary We administered 0.07 (group I), 0.2 (group II), and 0.7 (group III) mg/kg body wt. di(N-nitroso)perhydropyrimidine (DNPP) intraperitoneally to male Sprague-Dawley rats once a week for life. DNPP treatment resulted in reduced survival times according to a dose-related pattern. Median survival times from the beginning of the experiment were 888 days in controls, 482 days in group I, 463 days in group II, and 122 days in group III. DNPP induced squamous-cell carcinomas of the paranasal sinus. No treatment-related tumors were seen in the 40 rats treated with the lowest dose of DNPP.Type of Medium: Electronic ResourceURL: -
2Articles: DFG German National LicensesStaff View
ISSN: 1432-1335Source: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung 20 Wochen wurde Diäthylnitrosamin (DEN) oral 5 x wöchentlich in einer Einzeldosis (d) von 3 mg/kg Körpergewicht an 250 weibliche Wistar-Ratten verabreicht. Nach ∼150 Tagen wurde bei allen Tieren eine Probelaparotomie durchgeführt. Danach erfolgte eine Einteilung in 4 Erkrankungsstadien entsprechend dem Inspektionsbefund der Leber, wobei das Ausmaß der Tumorbildung als Kriterium verwendet wurde. Die Auswirkungen einer Kombinationstherapie mit unterschiedlichen äquitoxischen Dosierungen von Adriamycin (Adm), Methotrexat (Mtx), 5-Fluorouracil (5-FU) und Cyclophosphamid (CP) auf Ratten mit chemisch induzierten Lebertumoren wurden untersucht. Ein Nutzen der Therapie konnte nicht festgestellt werden. Ein hemmender Einfluß der medikamentösen Therapie auf die Entwicklung der Lebertumoren, auf die Häufigkeit an Metastasen und auf das Auftreten von Tumoren anderer Organe ließ sich nicht zeigen. Die Parallelen dieser experimentellen Ergebnisse zur Klinik werden diskutiert.Notes: Summary Diethylnitrosamine (DEN) was applied orally to a total of 250 female Wistar rats in a single dose (d) of 3 mg/kg body weight 5 times a week for a duration of 20 weeks. After ∼ 150 days exploratory laparotomy was performed to all animals. By inspection of the liver they were divided into 4 stages of disease according to the extent of cancer formation. The reaction of rats with DEN induced liver tumors was tested using a 4-drug combination chemotherapy with different equitoxic doses of Adriamycin (Adm), Methotrexate (Mtx), 5-Fluorouracil (5-FU) and Cyclophosphamide (CP). No benifit of drug treatment could be noted. In drug treated animals no decrease in the development of the liver tumors, in the frequency of metastases nor in the frequency of tumors of other origin could be demonstrated. The parallels of chemotherapy in chemically induced liver cancer to clinical experience are discussed.Type of Medium: Electronic ResourceURL: -
3FIS Bildung LiteraturdatenbankStaff View
Type of Medium: articlePublication Date: 1998Keywords: Unterrichtspraxis ; Psychosomatik ; Homosexualität ; Sexualerziehung ; Sexualkunde ; Homosexueller ; LesbierinIn: Erziehung heute, (1998) H. 1, S. 43-45, 1022-2294Language: German -
4FIS Bildung LiteraturdatenbankStaff View
Type of Medium: articlePublication Date: 1990Keywords: Umweltschutz ; Energiewirtschaft ; Ausbildungsplatzangebot ; Deutschland-BRD ; StuttgartIn: Moderne Metalltechnik, Bd. 4 (1990) H. 8, S. 6-9, 0933-88101864-3515Language: German -
5Articles: DFG German National LicensesBongers, H. ; Gross, M. ; Habs, D. ; Maier, H. J. ; Sieber, T. ; Thirolf, P. G.
[S.l.] : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: At the new Munich high flux reactor FRM-II, the Munich Accelerator for Fission Fragments (MAFF) is under development. The main objective will be the production and study of new very heavy elements (Z〉100). To obtain this goal, intense beams of neutron rich isotopes (70〈A〈160) are required. Thermal neutron induced fission is considered the most suitable method to produce these isotopes due to the large fission cross section and high thermal neutron flux (〉1014 n/s*cm2) available at the new reactor. The target ion source design is based on the ANUBIS source at OSIRIS in Studvik, optimized for very high neutron fluxes. Using 1 g of 235U diluted in a graphite target, intensities of several 1011 ions/s for 91Kr, 132Sn, or 144Cs, e.g., are expected after mass separation. These singly charged ions will be charge bred in an electron cyclotron resonance ion source and then injected into the MAFF-LINAC to reach the energies at the Coulomb barrier. The production of intense ion beams of neutron rich isotopes by thermal neutron induced fission, the development of the target ion source, and the development of the fission target will be presented. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] By freezing out the motion between particles in a high-energy storage ring, it should be possible to create threads of ions, offering research opportunities beyond the realm of standard accelerator physics. The usual heating due to intra-beam collisions should completely vanish, giving rise to a ...Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0029-554XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesKramp, J. ; Habs, D. ; Kroth, R. ; Music, M. ; Schirmer, J. ; Schwalm, D. ; Broude, C.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Keywords: Nuclear reactionsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National Licensesvon Busch, H. ; Thirolf, P. ; Ender, C. ; Habs, D. ; Kock, F. ; Schulze, T. ; Schwalm, D.
Amsterdam : ElsevierStaff ViewISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesRebel, H. ; Schweimer, G.W. ; Schatz, G. ; Specht, J. ; Lohken, R. ; Hauser, G. ; Habs, D. ; Klewe-Nebenius, H.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Keywords: Nuclear reactionsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0370-2693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesDahlinger, M. ; Kankeleit, E. ; Habs, D. ; Schwalm, D. ; Schwartz, B. ; Simon, R.S. ; Burrows, J.D. ; Butler, P.A.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Keywords: Nuclear reactionsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesHennerici, W. ; Metag, V. ; Hennrich, H.J. ; Repnow, R. ; Wahl, W. ; Habs, D. ; Helmer, K. ; Helmolt, U.v. ; Kolb, B. ; Pelte, D. ; Schwalm, D. ; Heyng, H.W. ; Albrecht, R. ; Simon, R.S.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesHimmele, G. ; Backe, H. ; Butler, P.A. ; Habs, D. ; Metag, V. ; Specht, H.J. ; Wilhelmy, J.B.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Keywords: Nuclear reactionsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesMetag, V. ; Fischer, R.D. ; Kuhn, W. ; Muhlhans, R. ; Novotny, R. ; Habs, D. ; Helmolt, U.v. ; Heyng, H.W. ; Lazzarini, A. ; Kolb, B. ; Pelte, D. ; Schwalm, D. ; Adelberger, E. ; Jaeschke, E. ; Himmele, G. ; Hennrich, H.J. ; Albrecht, R. ; Kroth, R. ; Repnow, R. ; Simon, R.S. ; Hennerici, W. ; Wahl, W.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesWisshak, K. ; Klewe-Nebenius, H. ; Habs, D. ; Faust, H. ; Nowicki, G. ; Rebel, H.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Keywords: Nuclear reaction ; RadioactivitySource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: