Search Results - (Author, Cooperation:H. Y. Chang)
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1Staff View
Publication Date: 2015-01-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: CRISPR-Cas Systems/*genetics ; Genetic Engineering/*methods ; Genome, Human/*genetics ; Humans ; Melanoma/*genetics ; Transcriptional Activation/*geneticsPublished by: -
2J. D. Buenrostro ; B. Wu ; U. M. Litzenburger ; D. Ruff ; M. L. Gonzales ; M. P. Snyder ; H. Y. Chang ; W. J. Greenleaf
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Compartmentation ; Cell Cycle/genetics ; Cell Line ; Cells/classification/*metabolism ; Chromatin/*genetics/*metabolism ; DNA/genetics/metabolism ; Epigenesis, Genetic ; *Epigenomics ; Genome, Human/genetics ; Humans ; Microfluidics ; Signal Transduction ; Single-Cell Analysis/*methods ; Transcription Factors/metabolism ; Transposases/metabolismPublished by: -
3E. J. Grow ; R. A. Flynn ; S. L. Chavez ; N. L. Bayless ; M. Wossidlo ; D. J. Wesche ; L. Martin ; C. B. Ware ; C. A. Blish ; H. Y. Chang ; R. A. Pera ; J. Wysocka
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Antigens, Differentiation/metabolism ; Blastocyst/cytology/metabolism/*virology ; Cell Line ; DNA Methylation ; Endogenous Retroviruses/genetics/*metabolism ; Female ; Gene Products, gag/metabolism ; Humans ; Male ; Octamer Transcription Factor-3/metabolism ; Open Reading Frames/genetics ; Pluripotent Stem Cells/cytology/metabolism/*virology ; RNA, Messenger/genetics/metabolism ; Ribosomes/genetics/metabolism ; Terminal Repeat Sequences/genetics ; Transcription, Genetic/genetics ; Transcriptional Activation ; Viral Envelope Proteins/genetics/metabolism ; *Virus ActivationPublished by: -
4E. Calo ; R. A. Flynn ; L. Martin ; R. C. Spitale ; H. Y. Chang ; J. Wysocka
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Chromatin/genetics/metabolism ; DEAD-box RNA Helicases/*metabolism ; Genes, rRNA/*genetics ; Humans ; Positive Transcriptional Elongation Factor B/metabolism ; Protein Binding ; RNA Polymerase I/metabolism ; RNA Polymerase II/metabolism ; *RNA Processing, Post-Transcriptional ; RNA, Ribosomal/*biosynthesis/genetics/*metabolism ; RNA, Small Nucleolar/genetics/metabolism ; RNA-Binding Proteins/metabolism ; Ribonucleoproteins, Small Nuclear/chemistry/metabolism ; *Transcription, GeneticPublished by: -
5W. Huang ; B. Thomas ; R. A. Flynn ; S. J. Gavzy ; L. Wu ; S. V. Kim ; J. A. Hall ; E. R. Miraldi ; C. P. Ng ; F. Rigo ; S. Meadows ; N. R. Montoya ; N. G. Herrera ; A. I. Domingos ; F. Rastinejad ; R. M. Myers ; F. V. Fuller-Pace ; R. Bonneau ; H. Y. Chang ; O. Acuto ; D. R. Littman
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
6K. C. Wang ; Y. W. Yang ; B. Liu ; A. Sanyal ; R. Corces-Zimmerman ; Y. Chen ; B. R. Lajoie ; A. Protacio ; R. A. Flynn ; R. A. Gupta ; J. Wysocka ; M. Lei ; J. Dekker ; J. A. Helms ; H. Y. Chang
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-03-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Line ; Cells, Cultured ; Chromatin/*genetics/metabolism ; DNA, Intergenic/genetics ; Embryo, Mammalian/metabolism ; Fibroblasts/metabolism ; Gene Expression Regulation, Developmental/*genetics ; Gene Knockdown Techniques ; Genes, Homeobox/*genetics ; Histone-Lysine N-Methyltransferase/metabolism ; Histones/chemistry/metabolism ; Humans ; Lysine/metabolism ; Methylation ; Mice ; Molecular Sequence Data ; Multigene Family/genetics ; Organ Specificity ; RNA, Untranslated/*genetics ; Transcription, GeneticPublished by: -
7R. C. Spitale ; R. A. Flynn ; Q. C. Zhang ; P. Crisalli ; B. Lee ; J. W. Jung ; H. Y. Kuchelmeister ; P. J. Batista ; E. A. Torre ; E. T. Kool ; H. Y. Chang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-09-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
8Staff View
Publication Date: 2013-08-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Humans ; Male ; RNA, Long Noncoding/*genetics ; Receptors, Androgen/*metabolism ; Transcriptional Activation/*genetics ; Up-Regulation/*geneticsPublished by: -
9M. Kretz ; Z. Siprashvili ; C. Chu ; D. E. Webster ; A. Zehnder ; K. Qu ; C. S. Lee ; R. J. Flockhart ; A. F. Groff ; J. Chow ; D. Johnston ; G. E. Kim ; R. C. Spitale ; R. A. Flynn ; G. X. Zheng ; S. Aiyer ; A. Raj ; J. L. Rinn ; H. Y. Chang ; P. A. Khavari
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Cell Differentiation/*genetics ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Epidermis/*cytology/*metabolism ; Gene Expression Regulation ; High-Throughput Screening Assays ; Humans ; Keratinocytes ; Mutation ; Nucleotide Motifs/genetics ; Protein Binding ; RNA Stability/genetics ; RNA, Long Noncoding/*genetics/*metabolism ; RNA, Messenger/genetics/metabolism ; RNA-Binding Proteins/metabolism ; Skin Diseases/geneticsPublished by: -
10Y. Wan ; K. Qu ; Q. C. Zhang ; R. A. Flynn ; O. Manor ; Z. Ouyang ; J. Zhang ; R. C. Spitale ; M. P. Snyder ; E. Segal ; H. Y. Chang
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-01-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 3' Untranslated Regions/genetics ; Base Sequence ; Binding Sites ; Child ; Female ; Gene Expression Regulation/genetics ; Genome, Human/genetics ; Humans ; Male ; MicroRNAs/chemistry/genetics/metabolism ; *Nucleic Acid Conformation ; Open Reading Frames/genetics ; Point Mutation/genetics ; RNA/*chemistry/*genetics/metabolism ; RNA Splice Sites/genetics ; RNA-Binding Proteins/metabolism ; Transcriptome/*geneticsPublished by: -
11Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargoA. Mateja ; M. Paduch ; H. Y. Chang ; A. Szydlowska ; A. A. Kossiakoff ; R. S. Hegde ; R. J. Keenan
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-03-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine Triphosphatases/*chemistry/metabolism ; Crystallography, X-Ray ; Cytosol/enzymology ; Guanine Nucleotide Exchange Factors/*chemistry/metabolism ; Hydrophobic and Hydrophilic Interactions ; Membrane Proteins/*chemistry/metabolism ; Molecular Chaperones/chemistry/metabolism ; Multiprotein Complexes/chemistry/metabolism ; Protein Multimerization ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein Transport ; Saccharomyces cerevisiae Proteins/*chemistry/metabolismPublished by: -
12R. C. Spitale ; R. A. Flynn ; Q. C. Zhang ; P. Crisalli ; B. Lee ; J. W. Jung ; H. Y. Kuchelmeister ; P. J. Batista ; E. A. Torre ; E. T. Kool ; H. Y. Chang
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acylation ; Adenosine/analogs & derivatives ; Animals ; Binding Sites ; Cell Survival ; Click Chemistry ; Computational Biology ; Embryonic Stem Cells/cytology/metabolism ; *Gene Expression Regulation/genetics ; Genome/genetics ; Mice ; Models, Molecular ; *Nucleic Acid Conformation ; Protein Biosynthesis/genetics ; RNA/*chemistry/classification/*genetics/metabolism ; RNA-Binding Proteins/metabolism ; Regulatory Sequences, Ribonucleic Acid/genetics ; Ribosomes/metabolism ; Transcriptome/geneticsPublished by: -
13S. Cheloufi ; U. Elling ; B. Hopfgartner ; Y. L. Jung ; J. Murn ; M. Ninova ; M. Hubmann ; A. I. Badeaux ; C. Euong Ang ; D. Tenen ; D. J. Wesche ; N. Abazova ; M. Hogue ; N. Tasdemir ; J. Brumbaugh ; P. Rathert ; J. Jude ; F. Ferrari ; A. Blanco ; M. Fellner ; D. Wenzel ; M. Zinner ; S. E. Vidal ; O. Bell ; M. Stadtfeld ; H. Y. Chang ; G. Almouzni ; S. W. Lowe ; J. Rinn ; M. Wernig ; A. Aravin ; Y. Shi ; P. J. Park ; J. M. Penninger ; J. Zuber ; K. Hochedlinger
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-12-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cells, Cultured ; Cellular Reprogramming/*genetics ; Chromatin/metabolism ; Chromatin Assembly Factor-1/antagonists & inhibitors/genetics/*metabolism ; Gene Expression Regulation/genetics ; Heterochromatin/metabolism ; Mice ; Nucleosomes/metabolism ; RNA Interference ; Transduction, GeneticPublished by: -
14W. Huang ; B. Thomas ; R. A. Flynn ; S. J. Gavzy ; L. Wu ; S. V. Kim ; J. A. Hall ; E. R. Miraldi ; C. P. Ng ; F. W. Rigo ; S. Meadows ; N. R. Montoya ; N. G. Herrera ; A. I. Domingos ; F. Rastinejad ; R. M. Myers ; F. V. Fuller-Pace ; R. Bonneau ; H. Y. Chang ; O. Acuto ; D. R. Littman
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-12-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Chromatin/genetics/metabolism ; DEAD-box RNA Helicases/genetics/*metabolism ; Female ; Gene Expression Regulation/genetics ; Hair/abnormalities ; Hirschsprung Disease/genetics ; Humans ; Immunologic Deficiency Syndromes/genetics ; Inflammation/immunology/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mutation/genetics ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; Organ Specificity ; Osteochondrodysplasias/congenital/genetics ; Protein Binding ; RNA, Long Noncoding/genetics/*metabolism ; Th17 Cells/*immunology/*metabolism ; Transcription, Genetic/geneticsPublished by: -
15Staff View
Publication Date: 2018-10-19Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
16Staff View
Publication Date: 2018-10-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Medicine, Diseases, Online OnlyPublished by: -
17Bai, K. H. ; Hong, J. I. ; You, S. J. ; Choi, C. K. ; Chang, H. Y.
[S.l.] : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Plasma parameter variations as a function of a mixing ratio in an electron temperature control system using a grid are investigated. Under the grid, the electron temperature, as well as electron density, is a strong function of a mixing ratio. The electron temperature decreases with a mixing ratio of molecular gases (O2 and CF4), and the large inelastic cross section of molecular gas is the reason for the decrease in the electron temperature. When the length of sheath around the grid wires is comparable to the space between the grid wires, only 10% mixing of CF4 decreases the electron temperature to 0.8 eV in 10 mTorr Ar/CF4 plasma. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
18Bai, K. H. ; Hong, J. I. ; You, S. J. ; Chang, H. Y.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: In this paper we investigate the effects of substrate bias voltage on plasma parameters in temperature control using a grid system in inductively coupled plasma. Electron temperature can be controlled from 2.5 eV to 0.5 eV at 1 mTorr Ar plasma using grid bias voltage, and the electron temperature is a strong function of substrate bias voltage. The main control parameter determining the electron temperature is the potential difference between grid-biased voltage and the plasma potential in the temperature controlled region (ΔφII,g). When substrate bias voltage is negative, plasma parameters do not vary with substrate bias voltage due to constant ΔφII,g © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Chung, Chin Wook ; You, K.-I. ; Seo, S. H. ; Kim, S. S. ; Chang, H. Y.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The electron energy distribution functions (EEDFs) are measured by a rf compensated Langmuir probe in a solenoidal inductive reactor at various frequencies and at 2 mTorr of argon. The frequency dependence of the electron energy distribution function is clearly observed. The energy diffusion coefficients against the applied frequencies are calculated from the nonlocal heating theory. It is found that the bounce resonance electrons determine the energy diffusion coefficient shape and the electron energy distribution function at the bounce resonance energy in the energy diffusion coefficient begins to flatten. The exact bounce resonance condition in solenoidal inductive discharge is presented. It is reported that the frequency dependence of the EEDFs is mainly due to the electron bounce resonance in a finite-size solenoidal inductive discharge. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
20Bai, K. H. ; Hong, J. I. ; Chung, C. W. ; Kim, S. S. ; Chang, H. Y.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Pressure and He mixing effects on plasma parameters in electron temperature control using a grid system are investigated. Electron temperature is higher in lower pressure, when the electron temperature is high and not controlled. Electron density can be increased by about three times by decreasing the source gas pressure from 20 to 1 mTorr, and by about two times by He mixing in the temperature controlled region (diffusion region), while the electron density is decreased in the source region. This electron density increase is mainly due to the increase of the high energy electron population, and the measured electron energy distribution functions clearly show this. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: