Search Results - (Author, Cooperation:H. Schroeder)
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1Liu, T., Zhang, M., Terry, M. H., Schroeder, H., Wilson, S. M., Power, G. G., Li, Q., Tipple, T. E., Borchardt, D., Blood, A. B.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-03-31Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0026-895XElectronic ISSN: 1521-0111Topics: Chemistry and PharmacologyMedicinePublished by: -
2F. Biermann ; K. Abbott ; S. Andresen ; K. Backstrand ; S. Bernstein ; M. M. Betsill ; H. Bulkeley ; B. Cashore ; J. Clapp ; C. Folke ; A. Gupta ; J. Gupta ; P. M. Haas ; A. Jordan ; N. Kanie ; T. Kluvankova-Oravska ; L. Lebel ; D. Liverman ; J. Meadowcroft ; R. B. Mitchell ; P. Newell ; S. Oberthur ; L. Olsson ; P. Pattberg ; R. Sanchez-Rodriguez ; H. Schroeder ; A. Underdal ; S. C. Vieira ; C. Vogel ; O. R. Young ; A. Brock ; R. Zondervan
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-03-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Conservation of Natural Resources ; *Environment ; *Government ; *International Cooperation ; Policy ; Technology ; *United NationsPublished by: -
3M. E. Allentoft ; M. Sikora ; K. G. Sjogren ; S. Rasmussen ; M. Rasmussen ; J. Stenderup ; P. B. Damgaard ; H. Schroeder ; T. Ahlstrom ; L. Vinner ; A. S. Malaspinas ; A. Margaryan ; T. Higham ; D. Chivall ; N. Lynnerup ; L. Harvig ; J. Baron ; P. Della Casa ; P. Dabrowski ; P. R. Duffy ; A. V. Ebel ; A. Epimakhov ; K. Frei ; M. Furmanek ; T. Gralak ; A. Gromov ; S. Gronkiewicz ; G. Grupe ; T. Hajdu ; R. Jarysz ; V. Khartanovich ; A. Khokhlov ; V. Kiss ; J. Kolar ; A. Kriiska ; I. Lasak ; C. Longhi ; G. McGlynn ; A. Merkevicius ; I. Merkyte ; M. Metspalu ; R. Mkrtchyan ; V. Moiseyev ; L. Paja ; G. Palfi ; D. Pokutta ; L. Pospieszny ; T. D. Price ; L. Saag ; M. Sablin ; N. Shishlina ; V. Smrcka ; V. I. Soenov ; V. Szeverenyi ; G. Toth ; S. V. Trifanova ; L. Varul ; M. Vicze ; L. Yepiskoposyan ; V. Zhitenev ; L. Orlando ; T. Sicheritz-Ponten ; S. Brunak ; R. Nielsen ; K. Kristiansen ; E. Willerslev
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-06-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Archaeology/methods ; Asia/ethnology ; Asian Continental Ancestry Group/*genetics ; Cultural Evolution/*history ; DNA/genetics/isolation & purification ; Europe/ethnology ; European Continental Ancestry Group/*genetics ; *Fossils ; Gene Frequency/genetics ; Genetics, Population ; Genome, Human/*genetics ; *Genomics ; History, Ancient ; Human Migration/history ; Humans ; Lactose Intolerance/genetics ; Language/*history ; Polymorphism, Single Nucleotide/genetics ; Skin Pigmentation/geneticsPublished by: -
4Staff View
ISSN: 1434-0879Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0044-2313Keywords: Chemistry ; Inorganic ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: The reactions of anhydrous HBr gas with Pb3(PO4)2, Pb(NO3)2 and PbCO3 yield no addition compounds of IIBr, as found by earlier investigators in the case of the phosphate, but lead bromide (besides other reaction products) which is easily characterized by means of powder diagrams.Notes: Bei der Einwirkung von trockenem Bromwasserstoff auf Pb3(PO4)2, Pb(NO3)2 oder PbCO3 entsteht, wie Debye-Scherrer-Aufnahmen zeigen, Bleibromid. Der Befund steht im Gegensatz zu den Ergebnissen anderer Untersuchungen, denen zufolge HBr an Bleiphosphat und einige andere Bleisalze unter Bildung von Anlagerungskomplexen addiert werden soll.Type of Medium: Electronic ResourceURL: -
6Betz, J. [Verfasser] ; Schmidt-Hackenberg, Brigitte [Verfasser] ; Schröder, H. [Verfasser]
Published 1996Staff ViewType of Medium: articlePublication Date: 1996Keywords: Persönlichkeitsmerkmal ; Berufliche Qualifikation ; Industriekaufmann ; Mechaniker ; Quantitative Angaben ; AusbilderIn: Wirtschaft und Berufserziehung, Bd. 48 (1996) H. 1, S. 11-16, 0341-339XLanguage: German -
7Probleme und Ergebnisse psychologischer Forschung. : Textband zu aktuellen Forschungsprojekten:1 ff.Staff View
Type of Medium: bookPublication Date: 1980Keywords: Psychologische Forschung ; Allgemeine Psychologie ; Persönlichkeitspsychologie ; Pädagogische Psychologie ; Sozialpsychologie ; ExperimentLanguage: GermanNote: 1. 1980. 96 S. - 2. 1981. 104 S. - 3. 1982. 124 S. -
8Staff View
Publication Date: 2018-06-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Anthropology, Online OnlyPublished by: -
9Shan, Y., Guan, D., Hubacek, K., Zheng, B., Davis, S. J., Jia, L., Liu, J., Liu, Z., Fromer, N., Mi, Z., Meng, J., Deng, X., Li, Y., Lin, J., Schroeder, H., Weisz, H., Schellnhuber, H. J.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-28Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
10Staff View
Publication Date: 2018-12-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Anthropology, Genetics, Online OnlyPublished by: -
11Aronica, E. ; Frey, U. ; Wagner, M. ; Schroeder, H. ; Krug, M. ; Ruthrich, H. ; Catania, M. V. ; Nicoletti, F. ; Reymann, K. G.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Stimulation of [3H]inositol monophosphate 〈[3H]InsP) formation by ibotenate or trans-1-aminocyclopentyl-l, 3-dicarboxylic acid (t-ACPD) in rat hippocampal slices was enhanced after tetanic stimulation of die Schaffer collaterals projecting to the CA1 region (in vitro) or the perforant pathway projecting to the dentate gyms (in freely moving animals). This effect was observed 5 h (but not 2 h) after long-term potentiation (LTP) induction and was abolished if tetanic stimulation was performed in the presence of specific antagonists of N-methyl-D-aspartate receptors. The delayed increase in excitatory amino acid-induced polyphosphoinositide (PPI) hydrolysis was accompanied by an enhanced responsiveness to norepinephrine, whereas the basal and carbamylcholine-stimulated [3H]InsP formation were unchanged. These results suggest that an increased activity of „metabotropic” glutamate receptors may contribute to the synaptic mechanisms enabling the late expression and or maintenance of LTP. Accordingly, LTP decayed more rapidly (within 5 h) in rats repeatedly injected with LiCl (60–120 mg/kg, i.p., for 10 days), a treatment that led to a reduced efficacy of ibotenate and norepinephrine in stimulating PPI hydrolysis in hippocampal slices.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A novel magnetostriction measurement tool is developed for a thin soft-magnetic film on a nonmagnetostrictive substrate. The sensitivity is at least an order of magnitude better than prior art, and is adequate to measure a magnetostriction coefficient as small as 10−7–10−8 for a film as thin as 30 nm on a glass wafer of thickness 200 μm. To make a measurement, the sample wafer in the form of a rectangle is clamped near an edge, and a saturating rotating magnetic field of constant amplitude is applied in its plane; this rotating field causes the film to expand/contract in the direction of magnetization for a positive/negative magnetostriction coefficient and results in a periodic "warpage'' of the sample at a frequency that is twice the rotation frequency of the field. A continuous helium-neon laser beam incident on the sample is used to sense this small periodic warpage. The reflected laser beam is detected by a position sensor; its output is normalized to the laser beam intensity to account for intensity fluctuation effects, and then fed to a phase-sensitive lock-in amplifier that is referenced to twice the field rotation frequency. This tool has been developed, characterized, optimized for noise reduction by suitable selection of frequencies and suspension techniques, and applied to measure the saturated magnetostriction coefficients of ultrathin soft-magnetic Permalloy-based films.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Moisture adsorbed on a gold, copper, or silicon surface in atmospheric conditions can be detected by using a pulsed laser-induced heating of the surface (transient temperature rise (approximately-less-than)100 °C), and a continuous probe laser beam parallel to the surface to detect the transient refractive-index changes. The probe deflection signal can be interpreted as due to a compression pulse (produced by the heating and moisture desorption at the sample surface), followed by a rarefraction (produced by cooling and diffusional moisture readsorption). Using this interpretation of the transient probe deflection signal, the amount of moisture adsorbed at the samples for various surface temperatures and absolute moisture content in an ambient gas (e.g., nitrogen) can be monitored.Type of Medium: Electronic ResourceURL: -
14Oltman, Philip K. ; Goodenough, Donald R. ; Koulack, David ; Maclin, Edward ; Schroeder, H. Robert ; Flannagan, Michael J.
Oxford, UK : Blackwell Publishing Ltd
Published 1977Staff ViewISSN: 1469-8986Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: A recently-proposed model of dream recall phenomena (Koulack & Goodenough, 1976) assumes a short-term memory store which functions during sleep, and from which either dreams or externally-delivered stimuli can be retrieved if the subject is awakened during the life of the short-term trace. To test this assumption, two experiments were designed to examine short-term memory for auditory stimuli over intervals of uninterrupted stage-2 sleep. A random series of single-digit numbers was presented at the rate of one every 30 sec throughout the night, at an intensity slightly above normal conversational levels. Subjects habituated to the sound and did not awaken spontaneously. Experimental awakenings took place either at 1 sec (Experiment 1) or at 1, 5, or 10 sec (Experiment 2) after selected target stimuli, and the subjects were asked to recall which number they had heard. Significant recall was obtained over intervals of up to 10 sec, and the likelihood of recall was inversely related to reaction times to the awakening stimulus. Repeating the target numbers at 30-sec intervals increased EEG alpha activity and K-complex amplitude, suggesting that some form of trace persists for at least 30 sec.Type of Medium: Electronic ResourceURL: -
15Weber, A. ; Schröder, H. ; Thalberg, K. ; Marz, L.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Phospholipase A2 (E.C. 3.1.1.4.) is a major allergen of honey bee venom. It exists in a glycosylated and an unglycosylated variant. Both forms and the glycopeptide isolated after exhaustive proteolytic digestion were tested in RAST and RAST inhibition studies. IgE from 11 of 14 bee venom allergy sera exhibited significantly higher, and in two cases exclusive, affinity towards glycosylated phospholipase. In RAST inhibition experiments using phospholipase coupled to discs five of the sera were completely inhibited by glycopeptide at 0.1 mg/ml; four sera were partially inhibited and two sera could not be inhibited. Glycoasparagine, lacking all amino acids except the carbohydrate-linking asparagine, inhibits IgE-binding to glycopeptide discs up to 100%. These data clearly demonstrate that an oligosaccharide of a structural type frequently found in glycoproteins can represent an epitope which is recognized by IgE antibodies from allergic patients, which are specifically directed against the parent glycoprotein.Type of Medium: Electronic ResourceURL: -
16Rlfsen, W. ; Schröder, H. ; Tibell, C. ; Tibell, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Cat flea sensitivity is considered one of the most important skin diseases in cats and dogs. Cat fleas, however, are also a growing allergen problem for humans. Cat flea-specific IgE antibodies were studied in serum samples from 70 patients with suspected cat allergy, using RAST-based techniques and the nitrocellulose immunoblotting method. Results from RAST studies, using cat and cat flea as allergosorbents, showed that 46% of the patients were RAST positive against both cat and cat flea. 9 % of the patients were RAST positive only against the cat flea. The nitrocellulose immunoblotting experiments were in agreement with the RAST results showing specific IgE to cat flea. The results indicate that some cat-allergic patients have specific IgE both towards cat and cat flea but also that some of the patients with suspected cat allergy might have specific IgE towards the cat flea and not the cat. RAST-inhibition and immunoblotting experiments also indicate that the allergen composition of cat flea extract differs from that of cat extract, even if common allergens have been detected, leading to cross-reactivity in some sera.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The optical dissociation of I2 can be markedly suppressed, if the I2 molecule is weakly bound to one or more rare-gas (Rg) atoms (cage effect). A classical simulation of this process gives a fast disappearance of the cage effect and of the fluorescence intensity, as soon as the optical excitation energy Eω exceeds the dissociation energy of I2 by a certain amount of energy, which is controlled by the binding energy of I–Rgn in the ground state. For lower Eω the van der Waals potential between I2 and Rgn is strong enough in the asymptotic region to prevent the separating iodine atoms from dissociating. The oscillating I atoms can then transfer part of their vibrational energy to the Rg motion till the rare-gas atoms are evaporated. This mechanism gives a fluorescence spectrum of I2 with a cutoff at higher vibrational energies—smeared out only by the thermal excitation of the ground-state complex. The dependence of the spectrum on temperature and potential parameters has been investigated. At high excitation energies Eω a spectrum with an isolated peak can occur, if the van der Waals binding energy is increased or if more than one rare-gas atom is bound to I2. Other mechanisms which could result in a cage effect at higher Eω require a hard collision between an I and a rare-gas atom immediately after excitation. This is possible at high temperatures or for a linear conformation I–I–Rg. For an extended range of photon energies the simulations gave high yields of I–Rgn fragments from a I2–Rgn beam. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
19Kompa, K. L. ; Lamprecht, H. ; Schröder, H. ; Puretzky, A. A. ; Tyakht, V. V.
College Park, Md. : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The visible luminescence induced in the OsO4 molecule by the action of CO2-laser radiation was studied in a wide range of laser fluences (2–1000 J/cm2). A novel approach consisting in separating successive dissociation and fluence was developed experimentally to study the visible emission induced by multiple-photon excitation (MPE) in an IR-laser field. Three different luminescence stages with definite fluence thresholds were found in MPE of the OsO4 molecule. The luminescence spectra and the velocities of the luminescent species were measured at each stage. A theoretical model is proposed which explains the observed three-stage emission in OsO4 by the following sequence of processes taking place during the IR-laser pulse: inverse electronic relaxation (IER)–multiple-photon dissociation (MPD) of the parent molecule (OsO4–first stage)—IER–MPD of the primary fragment (OsO3-second stage)—IER–MPD of the secondary fragment (OsO2-third stage).Type of Medium: Electronic ResourceURL: -
20Wevers, A. ; Monteggia, L. ; Nowacki, S. ; Bloch, W. ; Schütz, U. ; Lindstrom, J. ; Pereira, E. F. R. ; Eisenberg, H. ; Giacobini, E. ; De Vos, R. A. I. ; Steur, E. N. H. Jansen ; Maelicke, A. ; Albuquerque, E. X. ; Schröder, H.
Oxford, UK : Blackwell Science Ltd
Published 1999Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Impairment of cholinergic transmission and decreased numbers of nicotinic binding sites are well-known features accompanying the cognitive dysfunction seen in Alzheimer’s disease (AD). In order to elucidate the underlying cause of this cholinoceptive dysfunction, the expression of two pharmacologically different nicotinic acetylcholine receptor (nAChR) subunits (α4, α7) was studied in the cerebral cortex of Alzheimer patients as compared to controls. Patch-clamp recordings of 14 dissociated neurons of control cortices showed responses suggesting the existence of α4- and α7-containing functional nAChRs in the human cortex. In cortices of Alzheimer patients and controls, the pattern of distribution and the number of α4 and α7 mRNA-expressing neurons were similar, whereas at the protein level a decrease in the density of α4- and α7-expressing neurons of ≈ 30% was observed in Alzheimer patients. The histotopographical correlation of nAChR expression with accompanying pathological changes, e.g. accumulation of hyperphosphorylated-tau (HP-tau) protein and β-amyloid showed that neurons in the vicinity of β-amyloid plaques bore both nAChR transcripts. Neurons heavily labelled for HP-tau, however, expressed little or no α4 and α7 mRNA. These results point to an impaired synthesis of nAChRs on the protein level as a possible cause of the cholinoceptive deficit in AD. Further investigations need to elucidate whether interactions of HP-tau with nAChR mRNA, or alterations in the quality of α4 and α7 transcripts give rise to decreased protein expression at the level of individual neurons.Type of Medium: Electronic ResourceURL: