Search Results - (Author, Cooperation:H. Qiao)

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  1. 1
    Staff View
    Publication Date:
    2018-04-05
    Publisher:
    The American Society for Pharmacology and Experimental Therapeutics
    Print ISSN:
    0022-3565
    Electronic ISSN:
    1521-0103
    Topics:
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
    Staff View
    Publication Date:
    2018-07-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Geochemistry, Geophysics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-04-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Chemistry
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Wu, H., Liu, J., Miao, S., Zhao, Y., Zhu, H., Qiao, M., Saris, P. E. J., Qiao, J.
    The American Society for Microbiology (ASM)
    Published 2018
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0099-2240
    Electronic ISSN:
    1098-5336
    Topics:
    Biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    H. Qiao ; Z. Shen ; S. S. Huang ; R. J. Schmitz ; M. A. Urich ; S. P. Briggs ; J. R. Ecker
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-09-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Active Transport, Cell Nucleus ; Arabidopsis/drug effects/*metabolism ; Arabidopsis Proteins/genetics/*metabolism ; Cell Nucleus/*metabolism ; Endoplasmic Reticulum/*metabolism ; Ethylenes/*metabolism/pharmacology ; Gases/metabolism/pharmacology ; Mutation ; Nuclear Localization Signals/genetics/metabolism ; Phosphorylation ; Protein Kinases/metabolism ; Proteolysis ; Receptors, Cell Surface/genetics/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2018-11-23
    Publisher:
    American Society of Hematology (ASH)
    Print ISSN:
    0006-4971
    Electronic ISSN:
    1528-0020
    Topics:
    Biology
    Medicine
    Keywords:
    Lymphoid Neoplasia, Clinical Trials and Observations
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Xu, C., Gao, J., Zhang, H.-F., Gao, N., Guo, Y.-y., Fang, Y., Wen, Q., Qiao, H.-L.
    The American Society for Pharmacology and Experimental Therapeutics (ASPET)
    Published 2018
    Staff View
    Publication Date:
    2018-08-07
    Publisher:
    The American Society for Pharmacology and Experimental Therapeutics (ASPET)
    Print ISSN:
    0090-9556
    Electronic ISSN:
    1521-009X
    Topics:
    Chemistry and Pharmacology
    Medicine
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Staff View
    Publication Date:
    2018-11-16
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1050-2947
    Electronic ISSN:
    1094-1622
    Topics:
    Physics
    Keywords:
    Fundamental concepts
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Qiao, H.-L. ; Yang, J. ; Zhang, Y.-W.

    Oxford, UK : Munksgaard International Publishers
    Published 2005
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background:  Excessive production of interleukin (IL)-4, IL-13 and interferon (IFN)-γ is thought to be important in the development of allergic disease and atopy. Several investigators have linked the IL-4 and IL-4R genes to allergic disease and atopy. The aim of this study is to further explore the mechanism of penicillins allergy and evaluate the possible role of the IL-4 C-589T and IL-4RαQ576R polymorphisms in modulating the allergic responses to penicillins.Methods:  Radioallergosorbent test (RAST) was used to detect eight kinds of specific immunoglobulin E (IgE) to penicillins in serum. Serum levels of IL-4, IL-13 and IFN-γ were measured by using enzyme-linked immunosorbent assay (ELISA). The IL-4 C-589T and IL-4RαQ576R polymorphisms were genotyped by polymerase chain reaction restriction fragment length polymorphism (PCR–RFLP).Results:  Compared with control subjects, there were significantly higher levels of IL-4, IL-13 and IFN-γ in allergic patients with positive specific IgE (P 〈 0.01), and the lower levels of IL-4 and IFN-γ were observed in allergic patients with negative specific IgE (P 〈 0.05). We found a growing trend of IL-4 and IL-13 levels with the kind increasing of positive specific IgE, and even there were significant correlations between the three kinds of cytokines and many kinds of specific IgE (P 〈 0.05). The IL-4Rα*Q576 allele was significantly increased in patients with penicillins allergy compared with control subjects (P 〈 0.01). Furthermore, the allele was strongly associated with increased serum-specific benzylpenicilloyl (BPO)-, phenoxomethylpenicillanyl (PVA)- or ampicillanyl (APA)-IgE levels in patients with positive specific IgE (P 〈 0.05).Conclusions:  These data suggest that IL-4, IL-13 and IFN-γ play an important roles in penicillins allergy. The IL-4RαQ576R polymorphism may involve in the development of penicillins allergy, and through modulating specific serum IgE levels.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Qiao, H. ; Jackson, K.W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0584-8547
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Qiao, H. ; Jackson, K.W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0584-8547
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Qiao, H. ; Mahmood, T.M. ; Jackson, K.W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0584-8547
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Qiao, H. ; Xu, Z.Z. ; Zhang, K.M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0749-6036
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Qiao, H.-L. ; Yang, J. ; Zhang, Y.-W.

    Oxford, UK : Munksgaard International Publishers
    Published 2004
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background:  Numerous studies have suggested that both genetic and environmental influences are involved in the pathogenesis of allergic disease and atopy. The objective of this investigation is to elucidate the underlying mechanism of penicillins allergy and improve the diagnostic methods.Methods:  Radioallergosorbent test was used to examine eight kinds of specific IgE antibodies, which included four kinds of major and minor antigenic determinants, respectively, in the sera of 448 patients with penicillins allergy and 101 healthy subjects. A restriction endonuclease fragment length polymorphism of a polymerase chain reaction product was used for analysis of the FcɛRIβ polymorphism.Results:  The positive rate of specific IgE in 448 patients was 58.26% (261), in which 37.28% (167) patients had positive IgE to major antigenic determinants and 47.09% (211) patients had positive IgE to minor antigenic determinants. Of the 179 patients with allergic history, 70.83% (17/24) patients had positive antibodies within 30 days, while 45.28% (24/53) had positive antibodies after 5 years. The positive reaction degree of skin test was absolutely correlated with specific IgE (P = 0.047). Among patients with positive specific IgE, significant differences of E237G genotype were observed between patients with positive benzylpenicillanyl (BPA)-, phenoxomethylpenicilloyl (PVO)- or ampicilloyl (APO)-IgE and control group (P = 0.015, 0.015, and 0.008, respectively). There were significant differences in E237G genotype between positive and negative BPA-, PVO- as well as APO-IgE patients (P = 0.014, 0.02, and 0.011, respectively).Conclusions:  The patients with penicillins allergy have positive specific IgE not only to major antigenic determinants but also to minor antigenic determinants. The E237G variant of the FcɛRIβ gene is involved in the development of penicillins allergy through the process for the production of specific IgE antibodies.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses