Search Results - (Author, Cooperation:H. Qiao)
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1Gao, J., Wang, Z., Wang, G.-J., Zhang, H.-X., Gao, N., Wang, J., Wang, C.-E., Chang, Z., Fang, Y., Zhang, Y.-F., Zhou, J., Jin, H., Qiao, H.-L.
The American Society for Pharmacology and Experimental Therapeutics
Published 2018Staff ViewPublication Date: 2018-04-05Publisher: The American Society for Pharmacology and Experimental TherapeuticsPrint ISSN: 0022-3565Electronic ISSN: 1521-0103Topics: MedicinePublished by: -
2H. Lin, D. Calvet, L. Chen, X. Chen, T. Dafni, C. Fu, J. Galan, K. Han, S. Hu, Y. Huo, I.G. Irastorza, X. Ji, X. Li, X. Li, J. Liu, H. Mirallas, D. Neyret, K. Ni, H. Qiao, X. Ren, Sh. Wang, Si. Wang, Y. Yang, Y. Yuan, T. Zhang and L. Zhao
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-06-19Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
3Yao, L., Garmash, O., Bianchi, F., Zheng, J., Yan, C., Kontkanen, J., Junninen, H., Mazon, S. B., Ehn, M., Paasonen, P., Sipilä, M., Wang, M., Wang, X., Xiao, S., Chen, H., Lu, Y., Zhang, B., Wang, D., Fu, Q., Geng, F., Li, L., Wang, H., Qiao, L., Yang, X., Chen, J., Kerminen, V.-M., Petäjä, T., Worsnop, D. R., Kulmala, M., Wang, L.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-07-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Geochemistry, GeophysicsPublished by: -
4Merchant, R. R., Edwards, J. T., Qin, T., Kruszyk, M. M., Bi, C., Che, G., Bao, D.-H., Qiao, W., Sun, L., Collins, M. R., Fadeyi, O. O., Gallego, G. M., Mousseau, J. J., Nuhant, P., Baran, P. S.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: ChemistryPublished by: -
5Wu, H., Liu, J., Miao, S., Zhao, Y., Zhu, H., Qiao, M., Saris, P. E. J., Qiao, J.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-03-06Publisher: The American Society for Microbiology (ASM)Print ISSN: 0099-2240Electronic ISSN: 1098-5336Topics: BiologyPublished by: -
6H. Qiao ; Z. Shen ; S. S. Huang ; R. J. Schmitz ; M. A. Urich ; S. P. Briggs ; J. R. Ecker
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-09-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Active Transport, Cell Nucleus ; Arabidopsis/drug effects/*metabolism ; Arabidopsis Proteins/genetics/*metabolism ; Cell Nucleus/*metabolism ; Endoplasmic Reticulum/*metabolism ; Ethylenes/*metabolism/pharmacology ; Gases/metabolism/pharmacology ; Mutation ; Nuclear Localization Signals/genetics/metabolism ; Phosphorylation ; Protein Kinases/metabolism ; Proteolysis ; Receptors, Cell Surface/genetics/*metabolismPublished by: -
7Chen, L. S., Bose, P., Cruz, N. D., Jiang, Y., Wu, Q., Thompson, P. A., Feng, S., Kroll, M. H., Qiao, W., Huang, X., Jain, N., Wierda, W. G., Keating, M. J., Gandhi, V.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-11-23Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid Neoplasia, Clinical Trials and ObservationsPublished by: -
8Fang, H., Zhao, X., Yang, H., Sun, P., Li, Y., Jiang, K., Li, P., Jiao, M., Liu, M., Qiao, H., Wu, Q.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-01-28Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Public healthPublished by: -
9Xu, C., Gao, J., Zhang, H.-F., Gao, N., Guo, Y.-y., Fang, Y., Wen, Q., Qiao, H.-L.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-08-07Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0090-9556Electronic ISSN: 1521-009XTopics: Chemistry and PharmacologyMedicinePublished by: -
10X. B. Li, B. Qiao, H. X. Chang, H. He, W. P. Yao, X. F. Shen, J. Wang, Y. Xie, C. L. Zhong, C. T. Zhou, S. P. Zhu, and X. T. He
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-11-16Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Fundamental conceptsPublished by: -
11Qiao, H.-L. ; Yang, J. ; Zhang, Y.-W.
Oxford, UK : Munksgaard International Publishers
Published 2005Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: Excessive production of interleukin (IL)-4, IL-13 and interferon (IFN)-γ is thought to be important in the development of allergic disease and atopy. Several investigators have linked the IL-4 and IL-4R genes to allergic disease and atopy. The aim of this study is to further explore the mechanism of penicillins allergy and evaluate the possible role of the IL-4 C-589T and IL-4RαQ576R polymorphisms in modulating the allergic responses to penicillins.Methods: Radioallergosorbent test (RAST) was used to detect eight kinds of specific immunoglobulin E (IgE) to penicillins in serum. Serum levels of IL-4, IL-13 and IFN-γ were measured by using enzyme-linked immunosorbent assay (ELISA). The IL-4 C-589T and IL-4RαQ576R polymorphisms were genotyped by polymerase chain reaction restriction fragment length polymorphism (PCR–RFLP).Results: Compared with control subjects, there were significantly higher levels of IL-4, IL-13 and IFN-γ in allergic patients with positive specific IgE (P 〈 0.01), and the lower levels of IL-4 and IFN-γ were observed in allergic patients with negative specific IgE (P 〈 0.05). We found a growing trend of IL-4 and IL-13 levels with the kind increasing of positive specific IgE, and even there were significant correlations between the three kinds of cytokines and many kinds of specific IgE (P 〈 0.05). The IL-4Rα*Q576 allele was significantly increased in patients with penicillins allergy compared with control subjects (P 〈 0.01). Furthermore, the allele was strongly associated with increased serum-specific benzylpenicilloyl (BPO)-, phenoxomethylpenicillanyl (PVA)- or ampicillanyl (APA)-IgE levels in patients with positive specific IgE (P 〈 0.05).Conclusions: These data suggest that IL-4, IL-13 and IFN-γ play an important roles in penicillins allergy. The IL-4RαQ576R polymorphism may involve in the development of penicillins allergy, and through modulating specific serum IgE levels.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0584-8547Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0584-8547Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0584-8547Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0749-6036Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsType of Medium: Electronic ResourceURL: -
16Qiao, H.-L. ; Yang, J. ; Zhang, Y.-W.
Oxford, UK : Munksgaard International Publishers
Published 2004Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: Numerous studies have suggested that both genetic and environmental influences are involved in the pathogenesis of allergic disease and atopy. The objective of this investigation is to elucidate the underlying mechanism of penicillins allergy and improve the diagnostic methods.Methods: Radioallergosorbent test was used to examine eight kinds of specific IgE antibodies, which included four kinds of major and minor antigenic determinants, respectively, in the sera of 448 patients with penicillins allergy and 101 healthy subjects. A restriction endonuclease fragment length polymorphism of a polymerase chain reaction product was used for analysis of the FcɛRIβ polymorphism.Results: The positive rate of specific IgE in 448 patients was 58.26% (261), in which 37.28% (167) patients had positive IgE to major antigenic determinants and 47.09% (211) patients had positive IgE to minor antigenic determinants. Of the 179 patients with allergic history, 70.83% (17/24) patients had positive antibodies within 30 days, while 45.28% (24/53) had positive antibodies after 5 years. The positive reaction degree of skin test was absolutely correlated with specific IgE (P = 0.047). Among patients with positive specific IgE, significant differences of E237G genotype were observed between patients with positive benzylpenicillanyl (BPA)-, phenoxomethylpenicilloyl (PVO)- or ampicilloyl (APO)-IgE and control group (P = 0.015, 0.015, and 0.008, respectively). There were significant differences in E237G genotype between positive and negative BPA-, PVO- as well as APO-IgE patients (P = 0.014, 0.02, and 0.011, respectively).Conclusions: The patients with penicillins allergy have positive specific IgE not only to major antigenic determinants but also to minor antigenic determinants. The E237G variant of the FcɛRIβ gene is involved in the development of penicillins allergy through the process for the production of specific IgE antibodies.Type of Medium: Electronic ResourceURL: