Search Results - (Author, Cooperation:H. Molina)
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1A. Hoshino ; B. Costa-Silva ; T. L. Shen ; G. Rodrigues ; A. Hashimoto ; M. Tesic Mark ; H. Molina ; S. Kohsaka ; A. Di Giannatale ; S. Ceder ; S. Singh ; C. Williams ; N. Soplop ; K. Uryu ; L. Pharmer ; T. King ; L. Bojmar ; A. E. Davies ; Y. Ararso ; T. Zhang ; H. Zhang ; J. Hernandez ; J. M. Weiss ; V. D. Dumont-Cole ; K. Kramer ; L. H. Wexler ; A. Narendran ; G. K. Schwartz ; J. H. Healey ; P. Sandstrom ; K. J. Labori ; E. H. Kure ; P. M. Grandgenett ; M. A. Hollingsworth ; M. de Sousa ; S. Kaur ; M. Jain ; K. Mallya ; S. K. Batra ; W. R. Jarnagin ; M. S. Brady ; O. Fodstad ; V. Muller ; K. Pantel ; A. J. Minn ; M. J. Bissell ; B. A. Garcia ; Y. Kang ; V. K. Rajasekhar ; C. M. Ghajar ; I. Matei ; H. Peinado ; J. Bromberg ; D. Lyden
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-11-03Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biomarkers/metabolism ; Brain/cytology/*metabolism ; Cell Line, Tumor ; Endothelial Cells/cytology/metabolism ; Epithelial Cells/cytology/metabolism ; Exosomes/*metabolism ; Female ; Fibroblasts/cytology/metabolism ; Genes, src ; Humans ; Integrin alpha6beta1/metabolism ; Integrin alpha6beta4/antagonists & inhibitors/metabolism ; Integrin beta Chains/metabolism ; Integrin beta4/metabolism ; Integrins/antagonists & inhibitors/*metabolism ; Kupffer Cells/cytology/metabolism ; Liver/cytology/*metabolism ; Lung/cytology/*metabolism ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis/*pathology/*prevention & control ; Organ Specificity ; Phosphorylation ; Receptors, Vitronectin/antagonists & inhibitors/metabolism ; S100 Proteins/genetics ; *TropismPublished by: -
2Staff View
ISSN: 0191-491XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: EducationType of Medium: Electronic ResourceURL: -
3Fernandez, C.I. ; Bergado, J. ; De La Cuetara, K. ; Nunez, N. ; Castellanos, O. ; Gonzalez, O. ; Torres, A. ; Macias, R. ; Molina, H. ; Alvarez, L.
Amsterdam : ElsevierStaff ViewISSN: 0167-4943Keywords: cognitive impairments ; hippocampus ; memory ; septal graftsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
4Fernandez, C. ; De La Cuetara, K. ; Castellanos, O. ; Gonzalez, O. ; Nunez, N. ; Alvarez, L. ; Macias, R. ; Torres, A. ; Molina, H. ; Soto, J. ; Pernas, R. ; Soler, W.
Amsterdam : ElsevierStaff ViewISSN: 0167-4943Keywords: age-dependent motor disability ; dopaminergic cells ; neurotransplantation ; sensorimotor coordination ; striatumSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0346-251XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesType of Medium: Electronic ResourceURL: -
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ISSN: 0346-251XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0346-251XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesType of Medium: Electronic ResourceURL: -
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ISSN: 1432-0533Keywords: Choroid plexus papilloma ; GFAP ; Immunoperoxidase ; Ependymal differentiation ; Infancy and childhoodSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Rubinstein and Brucher [18] tested 22 choroid plexus papillomas for the presence of glial fibrillary acidic protein (GFAP), using the immunoperoxidase technique and obtained focal positive results in nine cases, all of which were adults (19–66 years of age). They recommended performing a similar study in children with a view to determining the incidence of “ependymal differentiation”. Here we report an immunoperoxidase study of 32 cases (1 month to 14 years of age) of choroid plexus tumors in infancy and childhood tested for GFAP. Nineteen cases were classified as benign papillomas and 13 as malignant (four of which included benign areas). The most frequent site [15] was the lateral ventricle (22 cases). Next came the fourth ventricle (six cases), then the third ventricle (three cases), and lastly the pontocerebellar angle (one case). We found positive results focally in epithelial tumor cells in 11 of the 32 cases (34.3%). Nine were benign and two were maligant with areas of benign or differentiated papilloma. Positive cells were present in these areas. GFAP-positive cells were classified in two groups according to their location. Type 1 cells were located in the epithelium Some of them were small rounded in contact with the basement membrane, without reaching the surface; others were elongated and columnar, some extending into processes that reached the basement membrane or the vessel walls in the stroma of the papillae. Type 2 cells were observed in the stroma of the papillae; these were elongated and stained strongly. An interesting feature in five positive cases was the observation of nodes formed by Type 2 (stromal) cells and fibrils associated with Type 1 cells in the overlying epithelium. Our finding that glial differentiation in choroid plexus papilloma epithelial cells is as frequent in children as it had been reported to be in adults, does not support the idea of a greater capability of divergent differentiation in infancy and childhood.Type of Medium: Electronic ResourceURL: -
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ISSN: 1432-0533Keywords: Brain ; Cerebellum ; Infancy ; RhabdomyosarcomaSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Tumors of the central nervous system (CNS) composed of pure mesenchymal derivatives with both embryonal and mature striated muscle cells devoid of neuroblastic elements should be considered rhabdomyosarcomas. Some 13 cases have been reported, and here we study four additional cases in infancy under 3 years of age which represent 0.82% of 483 intracranial tumors studied by us at the Children's Hospital in the last 12 years. Two cases were localized in the temporal lobes, and two were in the cerebellar vermis. All of them were typical embryonal rhabdomyosarcomas at various stages of differentiation including undifferentiated mesenchymal cells, embryonal cells, and rhabdomyoblasts. Tumor cells achieved a higher degree of differentiation in the cerebellum, as shown by readily detectable immature muscle fibers which were consistently absent in tumors involving the brain. Myoglobin [peroxidase-antiper-oxidase (PAP) techniquel was positive throughout in rhabdomyoblasts and in immature muscle cells, whereas glial fibrillary acidic protein was negative in all four tumors. In spite of the well differentiated appearance of the cerebellar tumors, their behavior was highly malignant with extensive infiltration of brainstem leptomeninges in one case, and all patients survived for only a short time after surgery. These tumors may be observed in the midline structures of the posterior fossa and in the brain, but we suspect their true incidence might be higher if immunohistochemical techniques were applied.Type of Medium: Electronic ResourceURL: