Search Results - (Author, Cooperation:H. Matsushita)
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1Latest Papers from Table of Contents or Articles in PressH. Matsushita ; M. D. Vesely ; D. C. Koboldt ; C. G. Rickert ; R. Uppaluri ; V. J. Magrini ; C. D. Arthur ; J. M. White ; Y. S. Chen ; L. K. Shea ; J. Hundal ; M. C. Wendl ; R. Demeter ; T. Wylie ; J. P. Allison ; M. J. Smyth ; L. J. Old ; E. R. Mardis ; R. D. Schreiber
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-02-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Algorithms ; Animals ; Carrier Proteins/genetics/immunology ; DNA-Binding Proteins/deficiency/genetics ; Exome/*genetics/*immunology ; Histocompatibility Antigens Class I/immunology ; Humans ; Immunologic Surveillance/*immunology ; Male ; Methylcholanthrene ; Mice ; Microfilament Proteins/genetics/immunology ; Models, Immunological ; Neoplasms/chemically induced/*genetics/*immunology/pathology ; Reproducibility of Results ; Sarcoma/chemically induced/genetics/immunology/pathology ; T-Lymphocytes/*immunologyPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0165-1161Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesKitagawa, A. ; Yamada, S. ; Muramatsu, M. ; Ogawa, H. ; Sato, Y. ; Torikoshi, M. ; Yoshizawa, J. ; Sekiguchi, M. ; Hattori, T. ; Honda, Y. ; Kimura, T. ; Kobayashi, C. ; Matsushita, H. ; Okada, T. ; Sakamoto, H. ; Shibuya, S. ; Yamamoto, M. ; Sawada, K.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The Heavy Ion Medical Accelerator in Chiba (HIMAC) at National Institute of Radiological Sciences (NIRS) is the first heavy-ion accelerator complex dedicated to cancer therapy. HIMAC is equipped with two kinds of ion sources. The PIG ion source is an indirectly heated cathode type, which is operated with a very low-duty factor. The ECR ion source has a single closed ECR zone with 10 GHz microwaves. Both sources realize good stability and reproducibility with easy operation, and satisfy the requirements for radiotherapy. They have been successfully used for clinical trials since June of 1994, and several tens of cancer patients have already been treated with 290–400 MeV/u carbon beams. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesKitagawa, A. ; Yamada, S. ; Kohno, T. ; Murakami, T. ; Muramatsu, M. ; Noda, K. ; Ogawa, H. ; Sato, Y. ; Yamada, T. ; Yoshizawa, J. ; Fu, S. ; Sekiguchi, M. ; Ohshiro, Y. ; Hattori, T. ; Shibuya, S. ; Matsushita, H. ; Sawada, K. ; Morishita, O.
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The development of an electron cyclotron resonance ion source for the heavy ion medical accelerator in Chiba (HIMAC) injector is reported. The HIMAC is a heavy ion medical accelerator for cancer therapy. The electron cyclotron resonance (ECR) ion source is expected to provide a long lifetime, easy operation, and easy maintenance for medical use. The NIRS-ECR ion source has a single closed ECR stage, and a microwave frequency of 10 GHz is applied. Under the present performance, the output electrical currents of the ions are 2500 eμA for He1+, 300 eμA for C2+, 480 eμA for Ne3+, and 110 eμA for Ar6+. Stability of the intensity is better than 2%. The transmission efficiency through a low-energy beam-transport line with an acceptance of 200 πmm mrad is more than 70%; the typical 50% and 90% emittances of the injection beam with 8 keV/u are 20 and 80 πmm mrad, respectively. These performances satisfy the requirements for radiotherapy.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesXu, J. Z. ; Matsuo, M. ; Kamiyama, N. ; Matsushita, H. ; Sakai, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A distribution-analyzing latex immunoassay (DALIA), based on the agglutination of latex particles coupled with mite or wheat allergen, was developed to determine allergen-specific IgG in human sera. The immune complex between chemically coupled-allergen latex and specific IgG was agglutinated specifically and efficiently by employing an IgM-type monoclonal second antibody with strong amplification activity. The extent of agglutination was evaluated by determining the relative ratio of volumes (RV) of agglutinates to residual nonagglutinating particles with a particle counter. This method exhibited a high sensitivity (detection limit ≤ 5 munits/ml) in the determination of allergen-specific IgG, and no influence of inhibitory factors such as competitive antibodies (specific-IgA, -IgM) and nonspecific IgG (≤320 mg/ml) was observed. The concentrations of specific IgG against mite allergen in the sera of 130 allergy patients with atopic dermatitis and 52 normal subjects were 22.3 ± 12.3 and 16.5 ±4.2 units/ml, respectively, and the concentrations of specific IgG against wheat allergen in the same two groups were 5.4 ± 4.2 and 2.1 ± 2.2 units/ml, respectively. The coefficients of variation of intra- and interassay ranged from 3.4% to 11.2% in both cases. The present method is an excellent homogeneous immunoassay which may be used as a routine assay that can measure 50 samples per hour without prior treatment.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesMIZUTANI, T. ; YOSHIMURA, K. ; MATSUSHITA, H. ; SHIOZAWA, R. ; HARA, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Systemic necrotizing vasculitis involving cerebral blood vessels is described in a 30-year-old man with rheumatic heart disease and subacute bacterial endocarditis. Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission. The fever resolved with antibiotic therapy on the third hospital day but he then developed hemiplegia and multifocal seizures. The seizures progressed to uncontrollable status epilepticus accompanied by congestive heart failure and the patient died 20 d after admission. At autopsy, exudative and necrotizing vasculitis involving medium- to small-sized arteries was seen in the brain, the heart and the skeletal muscles. Rheumatic myocarditis and endocarditis and old rheumatic mitral valve deformities were also present. In addition, verrucous endocarditis in the mitral valve and Löhlein's focal glomerulonephritis were noted. We discuss the possible mechanism of the systemic necrotizing vasculitis in relation to rheumatic fever.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesOhbayashi, A. ; Hiraga, T. ; Okubo, M. ; Murase, T. ; Matsushita, H. ; Hara, M.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesFurukawa, M. ; Kodera, Y. ; Uemura, T. ; Hiroto, M. ; Matsushima, A. ; Kuno, H. ; Matsushita, H. ; Inada, Y.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesMatsumoto, K. ; Ebata, T. ; Koseki, K. ; Okano, K. ; Kawakami, H. ; Matsushita, H.
Amsterdam : ElsevierStaff ViewISSN: 0008-6215Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0009-8981Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesKajihara, Y. ; Koseki, K. ; Ebata, T. ; Kodama, H. ; Matsushita, H. ; Hashimoto, H.
Amsterdam : ElsevierStaff ViewISSN: 0008-6215Keywords: CMP-Neu5Ac ; CMP-[α-Neu5Ac-(2 -〉 8)-Neu5Ac] ; CMP-neuramic acid ; CMP-neuramic acid dimer, Synthesis ; Neuraminic acidSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0016-6480Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Keywords: (mdx mouse) ; Enzyme activity ; Muscular dystrophy ; Protease ; Trypsin-like enzymeSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesKoseki, K. ; Ebata, T. ; Kadokura, T. ; Kawakami, H. ; Ono, M. ; Matsushita, H.
Amsterdam : ElsevierStaff ViewISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0031-9422Keywords: Berberidaceae ; Epimedium sagittatum ; ionone derivative ; lignan ; phenylpropanoid.Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesKanazawa, H. ; Kurihara, N. ; Hirata, K. ; Fujiwara, H. ; Matsushita, H. ; Takeda, T.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: