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1C. Y. Lin ; S. Erkek ; Y. Tong ; L. Yin ; A. J. Federation ; M. Zapatka ; P. Haldipur ; D. Kawauchi ; T. Risch ; H. J. Warnatz ; B. C. Worst ; B. Ju ; B. A. Orr ; R. Zeid ; D. R. Polaski ; M. Segura-Wang ; S. M. Waszak ; D. T. Jones ; M. Kool ; V. Hovestadt ; I. Buchhalter ; L. Sieber ; P. Johann ; L. Chavez ; S. Groschel ; M. Ryzhova ; A. Korshunov ; W. Chen ; V. V. Chizhikov ; K. J. Millen ; V. Amstislavskiy ; H. Lehrach ; M. L. Yaspo ; R. Eils ; P. Lichter ; J. O. Korbel ; S. M. Pfister ; J. E. Bradner ; P. A. Northcott
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cerebellar Neoplasms/classification/*genetics/*pathology ; Enhancer Elements, Genetic/*genetics ; Female ; Gene Expression Regulation, Neoplastic/*genetics ; Gene Regulatory Networks/genetics ; Genes, Neoplasm/genetics ; Genes, Reporter/genetics ; Humans ; Male ; Medulloblastoma/*classification/genetics/*pathology ; Mice ; Reproducibility of Results ; Transcription Factors/*metabolism ; Zebrafish/geneticsPublished by: -
2J. C. Dohm ; A. E. Minoche ; D. Holtgrawe ; S. Capella-Gutierrez ; F. Zakrzewski ; H. Tafer ; O. Rupp ; T. R. Sorensen ; R. Stracke ; R. Reinhardt ; A. Goesmann ; T. Kraft ; B. Schulz ; P. F. Stadler ; T. Schmidt ; T. Gabaldon ; H. Lehrach ; B. Weisshaar ; H. Himmelbauer
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-12-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Beta vulgaris/*genetics ; Biofuels/supply & distribution ; Carbohydrate Metabolism ; Chromosomes, Plant/genetics ; Crops, Agricultural/*genetics ; Ethanol/metabolism ; Genome, Plant/*genetics ; Genomics ; In Situ Hybridization, Fluorescence ; Molecular Sequence Data ; Phylogeny ; Sequence Analysis, DNA ; Spinacia oleracea/geneticsPublished by: -
3V. Hovestadt ; D. T. Jones ; S. Picelli ; W. Wang ; M. Kool ; P. A. Northcott ; M. Sultan ; K. Stachurski ; M. Ryzhova ; H. J. Warnatz ; M. Ralser ; S. Brun ; J. Bunt ; N. Jager ; K. Kleinheinz ; S. Erkek ; U. D. Weber ; C. C. Bartholomae ; C. von Kalle ; C. Lawerenz ; J. Eils ; J. Koster ; R. Versteeg ; T. Milde ; O. Witt ; S. Schmidt ; S. Wolf ; T. Pietsch ; S. Rutkowski ; W. Scheurlen ; M. D. Taylor ; B. Brors ; J. Felsberg ; G. Reifenberger ; A. Borkhardt ; H. Lehrach ; R. J. Wechsler-Reya ; R. Eils ; M. L. Yaspo ; P. Landgraf ; A. Korshunov ; M. Zapatka ; B. Radlwimmer ; S. M. Pfister ; P. Lichter
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-05-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Binding Sites ; Cell Line, Tumor ; Chromatin/genetics/metabolism ; Chromatin Immunoprecipitation ; DNA Methylation/*genetics ; Female ; *Gene Expression Regulation, Neoplastic ; *Gene Silencing ; Genome/genetics ; Histones/metabolism ; Humans ; Medulloblastoma/*genetics/pathology ; Mice ; Promoter Regions, Genetic/genetics ; RNA-Binding Proteins/genetics ; Sequence Analysis, DNA/*methods ; Transcription Factors/metabolism ; Transcription, GeneticPublished by: -
4F. Odoardi ; C. Sie ; K. Streyl ; V. K. Ulaganathan ; C. Schlager ; D. Lodygin ; K. Heckelsmiller ; W. Nietfeld ; J. Ellwart ; W. E. Klinkert ; C. Lottaz ; M. Nosov ; V. Brinkmann ; R. Spang ; H. Lehrach ; M. Vingron ; H. Wekerle ; C. Flugel-Koch ; A. Flugel
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-08-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adoptive Transfer ; Animals ; Autoimmunity/immunology ; Blood-Brain Barrier/immunology ; Brain/cytology/immunology/*pathology ; Cell Adhesion Molecules, Neuronal/metabolism ; *Cell Movement ; Cerebrovascular Circulation ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/*immunology/*pathology ; Gene Expression Profiling ; Immunologic Memory ; Lung/cytology/immunology/*pathology ; Lymphocyte Activation ; Myelin Sheath/immunology ; Nerve Growth Factors/metabolism ; Rats ; Rats, Inbred Lew ; T-Lymphocytes/cytology/immunology/metabolism/*pathologyPublished by: -
5T. Lappalainen ; M. Sammeth ; M. R. Friedlander ; P. A. t Hoen ; J. Monlong ; M. A. Rivas ; M. Gonzalez-Porta ; N. Kurbatova ; T. Griebel ; P. G. Ferreira ; M. Barann ; T. Wieland ; L. Greger ; M. van Iterson ; J. Almlof ; P. Ribeca ; I. Pulyakhina ; D. Esser ; T. Giger ; A. Tikhonov ; M. Sultan ; G. Bertier ; D. G. MacArthur ; M. Lek ; E. Lizano ; H. P. Buermans ; I. Padioleau ; T. Schwarzmayr ; O. Karlberg ; H. Ongen ; H. Kilpinen ; S. Beltran ; M. Gut ; K. Kahlem ; V. Amstislavskiy ; O. Stegle ; M. Pirinen ; S. B. Montgomery ; P. Donnelly ; M. I. McCarthy ; P. Flicek ; T. M. Strom ; H. Lehrach ; S. Schreiber ; R. Sudbrak ; A. Carracedo ; S. E. Antonarakis ; R. Hasler ; A. C. Syvanen ; G. J. van Ommen ; A. Brazma ; T. Meitinger ; P. Rosenstiel ; R. Guigo ; I. G. Gut ; X. Estivill ; E. T. Dermitzakis
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-09-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Line, Transformed ; Exons/genetics ; Gene Expression Profiling ; Genetic Variation/*genetics ; Genome, Human/*genetics ; *High-Throughput Nucleotide Sequencing ; Humans ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; RNA, Messenger/analysis/genetics ; *Sequence Analysis, RNA ; Transcriptome/*geneticsPublished by: -
6D. T. Jones ; N. Jager ; M. Kool ; T. Zichner ; B. Hutter ; M. Sultan ; Y. J. Cho ; T. J. Pugh ; V. Hovestadt ; A. M. Stutz ; T. Rausch ; H. J. Warnatz ; M. Ryzhova ; S. Bender ; D. Sturm ; S. Pleier ; H. Cin ; E. Pfaff ; L. Sieber ; A. Wittmann ; M. Remke ; H. Witt ; S. Hutter ; T. Tzaridis ; J. Weischenfeldt ; B. Raeder ; M. Avci ; V. Amstislavskiy ; M. Zapatka ; U. D. Weber ; Q. Wang ; B. Lasitschka ; C. C. Bartholomae ; M. Schmidt ; C. von Kalle ; V. Ast ; C. Lawerenz ; J. Eils ; R. Kabbe ; V. Benes ; P. van Sluis ; J. Koster ; R. Volckmann ; D. Shih ; M. J. Betts ; R. B. Russell ; S. Coco ; G. P. Tonini ; U. Schuller ; V. Hans ; N. Graf ; Y. J. Kim ; C. Monoranu ; W. Roggendorf ; A. Unterberg ; C. Herold-Mende ; T. Milde ; A. E. Kulozik ; A. von Deimling ; O. Witt ; E. Maass ; J. Rossler ; M. Ebinger ; M. U. Schuhmann ; M. C. Fruhwald ; M. Hasselblatt ; N. Jabado ; S. Rutkowski ; A. O. von Bueren ; D. Williamson ; S. C. Clifford ; M. G. McCabe ; V. P. Collins ; S. Wolf ; S. Wiemann ; H. Lehrach ; B. Brors ; W. Scheurlen ; J. Felsberg ; G. Reifenberger ; P. A. Northcott ; M. D. Taylor ; M. Meyerson ; S. L. Pomeroy ; M. L. Yaspo ; J. O. Korbel ; A. Korshunov ; R. Eils ; S. M. Pfister ; P. Lichter
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-27Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/genetics ; Amino Acid Sequence ; Cell Transformation, Neoplastic ; Cerebellar Neoplasms/classification/diagnosis/*genetics/pathology ; Child ; Chromatin/metabolism ; Chromosomes, Human/genetics ; DEAD-box RNA Helicases/genetics ; DNA Helicases/genetics ; DNA-Binding Proteins/genetics ; Genome, Human/*genetics ; Genomics ; Hedgehog Proteins/metabolism ; High-Throughput Nucleotide Sequencing ; Histone Demethylases/genetics ; Humans ; Medulloblastoma/classification/diagnosis/*genetics/pathology ; Methylation ; Mutation/genetics ; Mutation Rate ; Neoplasm Proteins/genetics ; Nuclear Proteins/genetics ; Oncogene Proteins, Fusion/genetics ; Phosphoprotein Phosphatases/genetics ; Polyploidy ; Receptors, Cell Surface/genetics ; Sequence Analysis, RNA ; Signal Transduction ; T-Box Domain Proteins/genetics ; Transcription Factors/genetics ; Wnt Proteins/metabolism ; beta Catenin/geneticsPublished by: -
7Taylor, S.A.M. ; Snell, R.G. ; Buckler, A. ; Ambrose, C. ; Duyao, M. ; Church, D. ; Lin, C.S. ; Altherr, M. ; Bates, G.P. ; Groot, N. ; Barnes, G. ; Shaw, D.J. ; Lehrach, H. ; Wasmuth, J.J. ; Harper, P.S. ; Housman, D.E. ; MacDonald, M.E. ; Gusella, J.F.
[s.l.] : Nature Publishing Group
Published 1992Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] We have applied the technique of exon amplification to the isolation of genes from the chromosome 4p16.3 Huntington's disease (HD) candidate region. Exons recovered from cosmid Y24 identified cDNA clones corresponding to the α–subunit of adducin, a calmodulin–binding protein that ...Type of Medium: Electronic ResourceURL: -
8Bates, G. P. ; Valdes, J. ; Hummerich, H. ; Baxendale, S. ; Le Paslier, D. L. ; Monaco, A. P. ; Tagle, D. ; MacDonald, M. E. ; Altherr, M. ; Ross, M. ; Brownstein, B. H. ; Bentley, D. ; Wasmuth, J. J. ; Gusella, J. F. ; Cohen, D. ; Collins, F. ; Lehrach, H.
[s.l.] : Nature Publishing Group
Published 1992Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] The Huntington's disease (HD) gene has been localized by recombination events to a region covering 2.2 megabases (Mb) DNA within chromosome 4p16.3. We have screened three yeast artificial chromosome (YAC) libraries in order to isolate and characterize 44 YAC clones mapping to this region. ...Type of Medium: Electronic ResourceURL: -
9McCombie, W.R. ; Martin-Gallardo, A. ; Gocayne, J.D. ; FitzGerald, M. ; Dubnick, M. ; Kelley, J.M. ; Castilla, L. ; Liu, L.I. ; Wallace, S. ; Trapp, S. ; Tagle, D. ; Whaley, W.L. ; Cheng, S. ; Gusella, J. ; Frischauf, A.-M. ; Poustka, A. ; Lehrach, H. ; Collins, F. S. ; Kerlavage, A. R. ; Fields, C. ; Venter, J.C.
[s.l.] : Nature Publishing Group
Published 1992Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] The sequences of three cosmids (90 kilobases) from the Huntington's disease region in chromosome 4p16.3 have been determined. A 30,837 base overlap of DNA sequenced from two individuals was found to contain 72 DNA sequence polymorphisms, an average of 2.3 polymorphisms per kilobase (kb). The ...Type of Medium: Electronic ResourceURL: -
10Watanabe, H. ; Fujiyama, A. ; Hattori, M. ; Taylor, T. D. ; Toyoda, A. ; Kuroki, Y. ; Noguchi, H. ; BenKahla, A. ; Lehrach, H. ; Sudbrak, R. ; Kube, M. ; Taenzer, S. ; Galgoczy, P. ; Platzer, M. ; Scharfe, M. ; Nordsiek, G. ; Blöcker, H. ; Hellmann, I. ; Khaitovich, P. ; Pääbo, S. ; Reinhardt, R. ; Zheng, H.-J. ; Zhang, X.-L. ; Zhu, G.-F. ; Wang, B.-F.
[s.l.] : Macmillian Magazines Ltd.
Published 2004Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Human–chimpanzee comparative genome research is essential for narrowing down genetic changes involved in the acquisition of unique human features, such as highly developed cognitive functions, bipedalism or the use of complex language. Here, we report the high-quality DNA sequence of 33.3 ...Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0378-1119Keywords: Bacteriophage λ ; M13 origin ; polylinker ; recombinant DNA ; subcloning ; vectorSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0378-1119Keywords: Linking library ; cosmids ; recombinant DNA toolsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0378-1119Keywords: Recombinant DNA ; cos sequence ; oligonucleotide probe ; partial digestion ; λEMBL3Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
14Rackwitz, H.R. ; Zehetner, G. ; Murialdo, H. ; Delius, H. ; Chai, J.H. ; Poustka, A. ; Frischauf, A. ; Lehrach, H.
Amsterdam : ElsevierStaff ViewISSN: 0378-1119Keywords: Recombinant DNA ; Ter-mediated cleavage ; restriction mappingSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0378-1119Keywords: Bam5 family ; Recombinant DNA ; cytoskeletal actin ; multi-gene family ; nucleotide sequence ; λ genomic librarySource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0378-1119Keywords: NotI sites ; Recombinant DNA ; bacteriophage λ ; chromosome walking ; cloning techniques ; non-homology to pUC plasmidsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
18Youngman, S. ; Sarfarazi, M. ; Bucan, M. ; MacDonald, M. ; Smith, B. ; Zimmer, M. ; Gilliam, C. ; Frischauf, A.-M. ; Shaw, D.J. ; Lehrach, H. ; Gusella, J.F. ; Wasmuth, J.J. ; Harper, P.S.
Amsterdam : ElsevierStaff ViewISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
19Cheng, S.V. ; Martin, G.R. ; Nadeau, J.H. ; Haines, J.L. ; Bucan, M. ; Kozak, C.A. ; MacDonald, M.E. ; Lockyer, J.L. ; Ledley, F.D. ; Lehrach, H. ; Gusella, J.F. ; Woo, S.L.C. ; Gilliam, T.C.
Amsterdam : ElsevierStaff ViewISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: