Search Results - (Author, Cooperation:H. Kanki)
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1K. Ishizuka ; A. Kamiya ; E. C. Oh ; H. Kanki ; S. Seshadri ; J. F. Robinson ; H. Murdoch ; A. J. Dunlop ; K. Kubo ; K. Furukori ; B. Huang ; M. Zeledon ; A. Hayashi-Takagi ; H. Okano ; K. Nakajima ; M. D. Houslay ; N. Katsanis ; A. Sawa
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-04-08Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; COS Cells ; Cell Movement/genetics ; Cell Proliferation ; Cercopithecus aethiops ; Cerebral Cortex/cytology/*embryology/physiology ; Gene Knockdown Techniques ; Glycogen Synthase Kinase 3/metabolism ; HEK293 Cells ; Humans ; Mice ; Microtubule-Associated Proteins/genetics/metabolism ; *Nerve Tissue Proteins/genetics/metabolism ; Neurons/*cytology/metabolism/*physiology ; PC12 Cells ; Phosphorylation ; Protein Binding ; Rats ; Signal Transduction ; Stem Cells/*cytology ; Wnt Proteins/metabolism ; beta Catenin/metabolismPublished by: -
2Yoshizaki, Y. ; Kanki, H. ; Ueda, T. ; Ichihashi, M. ; Ueda, M.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
3Kamitsuji, H. ; Tani, K. ; Yasui, M. ; Taniguchi, A. ; Taira, K. ; Tsukada, S. ; Iida, Y. ; Kanki, H. ; Fukui, H.
Springer
Published 1987Staff ViewISSN: 1432-1076Keywords: Henoch-Schönlein purpura ; Factor XIII ; Substitution therapy ; Blood coagulation ; Allergic vasculitisSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Determination of coagulation Factor XIII (F XIII)-related parameters in 21 patients with Henoch-Schönlein purpura documented a significant decrease of F XIII activity as well as of the F XIII-related antigenic determinants. Subgroup analysis with regard to the clinical symptoms showed an even further decrease of these parameters in patients with gastrointestinal complications. Stimulated by these findings a substitution therapy with a F XIII concentrate was initiated in those patients whose F XIII activity in plasma remained low and who developed severe abdominal pain accompanied by persisting gastrointestinal bleeding. This therapeutic approach not only corrected the laboratory data, but more important led to a cessation of pain and bleeding. A rapid decrease of F XIII levels after transfusion below 40 U/ml was indicative of relapse of abdominal symptoms, while increasing values were associated with the recovery of the patients. In conclusion: F XIII activity determinations appear to have a predictive value in patients with Henoch-Schönlein purpura, and the administration of F XIII concentrates may contribute to the improvement of gastrointestinal complications.Type of Medium: Electronic ResourceURL: