Search Results - (Author, Cooperation:H. Huynh)

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  1. 1
    Staff View
    Publication Date:
    2018-09-27
    Publisher:
    Nature Publishing Group (NPG)
    Electronic ISSN:
    2041-1723
    Topics:
    Biology
    Chemistry and Pharmacology
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Base Sequence ; Bone Neoplasms/genetics/pathology/*prevention & control/*secondary ; Bone Resorption/drug therapy/genetics ; Cell Differentiation/drug effects/*genetics ; Cell Line, Tumor ; Disease Models, Animal ; Female ; Gene Deletion ; Homeodomain Proteins/antagonists & inhibitors/genetics/metabolism ; Humans ; Male ; Mammary Neoplasms, Animal/pathology ; Mice ; Mice, Transgenic ; MicroRNAs/*genetics/pharmacology/therapeutic use ; Neoplasm Transplantation ; Organ Size/drug effects ; Osteoclasts/drug effects/*pathology ; Osteoporosis/genetics/pathology/*prevention & control ; Ovariectomy ; Repressor Proteins/antagonists & inhibitors/*deficiency/genetics/metabolism ; Skin Neoplasms/pathology ; Transgenes ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    J. Zheng ; M. Umikawa ; C. Cui ; J. Li ; X. Chen ; C. Zhang ; H. Huynh ; X. Kang ; R. Silvany ; X. Wan ; J. Ye ; A. P. Canto ; S. H. Chen ; H. Y. Wang ; E. S. Ward ; C. C. Zhang
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Differentiation ; Cell Division ; Cells, Cultured ; Disease Models, Animal ; Fetal Blood/cytology/metabolism ; HEK293 Cells ; Hematopoietic Stem Cells/*cytology/*metabolism ; Humans ; Leukemia/*metabolism/*pathology ; Membrane Glycoproteins/genetics/*metabolism ; Mice ; Myeloid-Lymphoid Leukemia Protein ; Receptors, Immunologic/genetics/*metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Huynh, H. ; Luk, S. L. ; Singh, R. ; Pavuluri, M. ; Mathai, J.

    Oxford, UK and Boston, USA : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1475-3588
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Psychology
    Notes:
    Many studies have demonstrated the short-term efficacy of stimulant drugs in decreasing the symptoms of Attention Deficit Hyperactivity Disorder (ADHD). However, long-term studies have not shown a similar effect. In this study, we report an audit of the medium-term outcome of 50 children with ADHD referred to a mental health service and treated with stimulants for at least 6 months. A poor outcome group was identified consisting of 30% of the children. As a group, they received a significantly higher dose of stimulant. More studies, with prospective design, are required to examine the medium-term outcome of children with ADHD on medication.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/1475-3588.00252

    Articles: DFG German National Licenses
  5. 5
    Phan, T.T. ; See, P. ; Tran, E. ; Nguyen, T.T.T. ; Chan, S.Y. ; Lee, S.T. ; Huynh, H.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary Background Keloids are characterized by abnormal proliferation of fibroblasts and overproduction of collagen. Insulin-like growth factor (IGF)-I is mitogenic for fibroblasts and a stimulatory factor for collagen synthesis. Objectives We have assessed the in vitro effects of quercetin on proliferation, collagen synthesis and the expression of the IGF system in keloid-derived fibroblasts. Methods Fibroblasts were isolated from earlobe keloids and exposed to quercetin at different concentrations. The inhibitory effects of quercetin on fibroblast proliferation were assayed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, Western and Northern blot analyses. Results Quercetin inhibited keloid fibroblast (KF) proliferation in a dose-dependent manner. Significant growth inhibition was observed on day 2 of culture. The dose required for 50% growth inhibition was approximately 25 µg mL−1. Collagen 1 expression was significantly decreased while collagen 3 was almost undetectable following quercetin treatment. Basal levels of IGF-I receptor (IGF-IR) β subunits, p85 subunit of phosphatidylinositol 3-kinase, c-Raf, phospho-Raf-1, phospho-MEK 1/2, phospho-mitogen-activated protein kinase, phospho-Elk-1 and phospho-Akt-1 were significantly reduced when KF cells were exposed to quercetin for 24 h. Blocking IGF-IR activity with IGF-IR antibody or neutralizing endogenous IGF-I activity with IGF-I antibody led to significant growth inhibition suggesting the role of IGF-I in regulation of KF proliferation. Conclusions Because the IGF system plays an important part in fibroblast cell proliferation and collagen production, the described activities of quercetin on the IGF system and collagen expression may provide a novel approach for the use of quercetin in treatment and/or prevention of hypertrophic scar and keloid.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2133.2003.05174.x

    Articles: DFG German National Licenses
  6. 6
    Huynh, H. ; Pollak, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1994.2175

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/geno.1993.1487

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0162-0134
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0162-0134(92)84137-C

    Articles: DFG German National Licenses
  9. 9
    Raghavan, D ; Huynh, H ; Ferraris, C. F
    Springer
    Published 1998
    Staff View
    ISSN:
    1573-4803
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract The workability and mechanical properties of mortar containing shredded automobile and truck tyres were evaluated. Two different shapes of rubber particles were used as constituents of mortar: (1) granules about 2 mm in diameter, and (2) shreds having two sizes which were, nominally, 5.5 mm×1.2 mm and 10.8 mm×1.8 mm (length×diameter). As expected, the geometry of the rubber particles influenced the fracture behaviour of rubber-containing mortar. The addition of rubber led to a decrease in flexural strength and plastic shrinkage cracking of mortar. The crack width and crack length due to plastic shrinkage were reduced for mortar containing the 10.8×1.8 mm rubber shreds compared with a mortar without shreds. The rheological properties of the mortar containing rubber shreds were comparable to those of a mortar without rubber and yielded lower plastic viscosity than a mortar containing 25.4 mm×15 μm (length×diameter) polypropylene fibres. The alkaline stability of rubber in mortar was also evaluated by immersing rubber shreds in NaOH and Ca(OH)2 solutions for 4 mon and the results showed that there is less than 20% change in stress and strain value. The findings of the research suggest that automobile and truck tyres can be recycled by shredding and incorporating them into mortar and probably concrete for certain infrastructural applications. © 1998 Chapman & Hall
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1004372414475

    Articles: DFG German National Licenses